B2 100 mg Ingredients & Drug Interactions
by Natural Grocers by Vitamin Cottage
What is this page for?
First and foremost: checking B2 100 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
B2 100 mg is a dietary supplement by Natural Grocers by Vitamin Cottage with 1 active ingredient. Its ingredients are commonly taken for riboflavin deficiency, migraine prevention, general energy and metabolism support.Based on those ingredients, 20 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Vitamin B2. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against B2 100 mg by Natural Grocers by Vitamin Cottage
Ask about any prescription or over-the-counter medication and we check it for interactions with B2 100 mg by Natural Grocers by Vitamin Cottage — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of B2 100 mg by Natural Grocers by Vitamin Cottage
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains one active ingredient: vitamin B2 (riboflavin), a B vitamin at 100 mg per capsule. The inactive ingredients are microcrystalline cellulose, silica, rice bran, and the capsule itself.
Does it work?
Couldn't assess
The product facts we hold do not include effectiveness ratings for vitamin B2, so the evidence we've documented doesn't establish whether this dose works for any particular purpose.
How safe is it?
Well-documented data
Riboflavin is generally well tolerated. The most common side effects are dose-related nausea and bright yellow urine; a small number of people have reported diarrhea or increased urination at higher doses.
Excess riboflavin is removed through your urine, making it very safe overall. For pregnancy and breastfeeding: riboflavin is needed during both and is rated likely safe at recommended amounts.
If you're pregnant or breastfeeding and thinking about a high-dose supplement like this, check with your doctor or pharmacist first.
Meds to double-check
Moderate interaction found
If you take tetracycline antibiotics, check with your doctor or pharmacist before using this product — riboflavin may reduce how well the antibiotic works.
The bottom line
Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
If you take tetracycline antibiotics (like doxycycline for acne or infection), talk to your doctor or pharmacist before starting this supplement — the B2 may interfere with the antibiotic's strength. Otherwise, riboflavin is generally well tolerated at this dose.
Your own healthcare provider can tell you whether this product fits your needs.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Oct 22, 2021.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about B2 100 mg, straight from the product label.
| Brand | Natural Grocers by Vitamin Cottage |
|---|---|
| Barcode (UPC) | 849327003208 |
| Net contents | 90 Vegetarian Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Oct 22, 2021 |
| DSLD ID | 256904 |
| Product type | Vitamin |
| Supplement form | Capsule |
| Dietary claims / uses | Nutrient, All Other, Structure/Function |
| Intended target group(s) | Vegetarian, Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for B2 100 mg by Natural Grocers by Vitamin Cottage, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Vitamin B2 | 100 mg | 7692% |
Other ingredients: Microcrystalline Cellulose, Capsule, Silica, Rice Bran
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements
Our unique story It was 1955 when Margaret and Philip Isely started Natural Grocers with $200 and a dream to make healthy living attainable for everyone. Now this family legacy is evolving with Natural Grocers Brand supplements, bringing you premium quality products at Always Affordable prices.
Formulation
We only put our name on formulas that meet our unrivaled quality standards, and we continue raising the bar on these standards without raising the bar on your budget. Our supplements are GMP (Good Manufacturing Practices) certified, ingredient verified, screened for heavy metals, and formulated without questionable fillers, artificial colors, sweeteners, flavors, and other problematic ingredients. We scrutinize every detail, so you don't have to, because we are, and always have been, your Original good4u Grocers. To your health, - The Isely Family
Our supplements are GMP (Good Manufacturing Practices) certified, ingredient verified, screened for heavy metals, and formulated without questionable fillers, artificial colors, sweeteners, flavors, and other problematic ingredients.
Metabolism support
Gluten free
Vegetarian
BPA Free
Contains no: Sugar, salt, dairy, yeast, wheat, gluten, corn, soy, preservatives, magnesium stearate, artificial colors or flavors.
Seals/Symbols
GMP Good Manufacturing Practice
Made in USA
FDA Statement of Identity
Dietary Supplement
Suggested/Recommended/Usage/Directions
Suggested use: As a dietary supplement, adults take one (1) vegetarian capsule daily, or as directed by a health care professional.
Storage
Store in a cool, dry place and away from direct light.
Precautions
Caution: As with any supplement, consult your healthcare practitioner before using this product, especially if you are pregnant, nursing, or are under medical supervision for any reason.
Keep out of reach of children.
For serious adverse event reporting call (877) 455-2826.
FDA Disclaimer Statement
This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
B2 100 mg by Natural Grocers by Vitamin Cottage label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in B2 100 mg by Natural Grocers by Vitamin Cottage
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 Vegetarian Capsule(s) Dosage formCapsule Servings per container90 Amounts shown are per serving.
Vitamin B2
Interacts with20 drugs
Riboflavin (vitamin B2) is an essential nutrient your body needs to turn food into energy and to keep skin, eyes, and nerves healthy. It is generally...
Vitamin B2 monograph & interactionsOther (inactive) ingredients: Microcrystalline Cellulose, Capsule, Silica, Rice Bran. These complete the product’s ingredient list but are not active constituents.
B2 100 mg by Natural Grocers by Vitamin Cottage Drug Interactions
HelloPharmacist Interaction Report
Natural Grocers' B2 100 mg contains one active ingredient — vitamin B2 (riboflavin) — which has documented interactions with tetracycline antibiotics.
Lab research suggests riboflavin may weaken how well these antibiotics work, though this hasn't been confirmed in actual patients yet; the interaction is rated Moderate.
Read the full breakdown — every affected drug type, severity by severity
Tetracycline antibiotics (like doxycycline and minocycline) are the main concern. If you take one of these, check with your doctor or pharmacist before adding this supplement — they may need to adjust your timing or dosing to keep the antibiotic effective.
Altogether, these interactions span 20 individual medications. No other interactions are documented for riboflavin in our data.
Use the medication checker on this page to confirm your exact prescriptions before you start.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against B2 100 mg?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in B2 100 mg interact with 20 drugs. Click any drug to see the details.
1 of the 1 ingredient in B2 100 mg interact with drugs. Each result below shows which ingredient is responsible. Vitamin B2
Amphotericin, TetracyclineMysteclin-F
How Amphotericin, Tetracycline interacts with B2 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Vitamin B2Tetracycline Antibiotics Moderate
Interaction Summary
Theoretically, taking riboflavin with tetracycline antibiotics may decrease the potency of these antibiotics.
Read the full Vitamin B2 + Amphotericin, Tetracycline interactionBismuth Subsalicylate, Metronidazole, TetracyclineHelidac
How Bismuth Subsalicylate, Metronidazole, Tetracycline interacts with B2 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Vitamin B2Tetracycline Antibiotics Moderate
Interaction Summary
Theoretically, taking riboflavin with tetracycline antibiotics may decrease the potency of these antibiotics.
Read the full Vitamin B2 + Bismuth Subsalicylate, Metronidazole, Tetracycline interactionChlortetracyclineAureomycin
How Chlortetracycline interacts with B2 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Vitamin B2Tetracycline Antibiotics Moderate
Interaction Summary
Theoretically, taking riboflavin with tetracycline antibiotics may decrease the potency of these antibiotics.
Read the full Vitamin B2 + Chlortetracycline interactionDemeclocyclineDeclomycin
How Demeclocycline interacts with B2 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Vitamin B2Tetracycline Antibiotics Moderate
Interaction Summary
Theoretically, taking riboflavin with tetracycline antibiotics may decrease the potency of these antibiotics.
Read the full Vitamin B2 + Demeclocycline interactionDoripenemDoribax
How Doripenem interacts with B2 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Vitamin B2Tetracycline Antibiotics Moderate
Interaction Summary
Theoretically, taking riboflavin with tetracycline antibiotics may decrease the potency of these antibiotics.
Read the full Vitamin B2 + Doripenem interactionDoxycyclineDoryx, Doxy, Doxy-D, Doxycin, Doxycycline Injection, Doxylin +6 more
How Doxycycline interacts with B2 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Vitamin B2Tetracycline Antibiotics Moderate
Interaction Summary
Theoretically, taking riboflavin with tetracycline antibiotics may decrease the potency of these antibiotics.
Read the full Vitamin B2 + Doxycycline interactionDoxycycline HyclateActiclate, Acticlate Cap, Lymepak
How Doxycycline Hyclate interacts with B2 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Vitamin B2Tetracycline Antibiotics Moderate
Interaction Summary
Theoretically, taking riboflavin with tetracycline antibiotics may decrease the potency of these antibiotics.
Read the full Vitamin B2 + Doxycycline Hyclate interactionDoxycycline MonohydrateErfacea
How Doxycycline Monohydrate interacts with B2 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Vitamin B2Tetracycline Antibiotics Moderate
Interaction Summary
Theoretically, taking riboflavin with tetracycline antibiotics may decrease the potency of these antibiotics.
Read the full Vitamin B2 + Doxycycline Monohydrate interactionDoxycylineDoxychel
How Doxycyline interacts with B2 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Vitamin B2Tetracycline Antibiotics Moderate
Interaction Summary
Theoretically, taking riboflavin with tetracycline antibiotics may decrease the potency of these antibiotics.
Read the full Vitamin B2 + Doxycyline interactionEravacyclineXerava
How Eravacycline interacts with B2 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Vitamin B2Tetracycline Antibiotics Moderate
Interaction Summary
Theoretically, taking riboflavin with tetracycline antibiotics may decrease the potency of these antibiotics.
Read the full Vitamin B2 + Eravacycline interactionMetronidazole, Tetracyline, Bismuth Subcitrate PotassiumPylera
How Metronidazole, Tetracyline, Bismuth Subcitrate Potassium interacts with B2 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Vitamin B2Tetracycline Antibiotics Moderate
Interaction Summary
Theoretically, taking riboflavin with tetracycline antibiotics may decrease the potency of these antibiotics.
Read the full Vitamin B2 + Metronidazole, Tetracyline, Bismuth Subcitrate Potassium interactionMinocyclineAcnamino MR, Aknemin, Amzeeq, Arestin Miscrosperes, Dynacin, Minocin +6 more
How Minocycline interacts with B2 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Vitamin B2Tetracycline Antibiotics Moderate
Interaction Summary
Theoretically, taking riboflavin with tetracycline antibiotics may decrease the potency of these antibiotics.
Read the full Vitamin B2 + Minocycline interactionMinocycline HydrochlorideMinolira, Ximino
How Minocycline Hydrochloride interacts with B2 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Vitamin B2Tetracycline Antibiotics Moderate
Interaction Summary
Theoretically, taking riboflavin with tetracycline antibiotics may decrease the potency of these antibiotics.
Read the full Vitamin B2 + Minocycline Hydrochloride interactionOmadacycline (iv)Nuzyra
How Omadacycline (iv) interacts with B2 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Vitamin B2Tetracycline Antibiotics Moderate
Interaction Summary
Theoretically, taking riboflavin with tetracycline antibiotics may decrease the potency of these antibiotics.
Read the full Vitamin B2 + Omadacycline (iv) interactionOmadacycline (oral)Nuzyra
How Omadacycline (oral) interacts with B2 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Vitamin B2Tetracycline Antibiotics Moderate
Interaction Summary
Theoretically, taking riboflavin with tetracycline antibiotics may decrease the potency of these antibiotics.
Read the full Vitamin B2 + Omadacycline (oral) interactionOxytetracyclineTerramycin
How Oxytetracycline interacts with B2 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Vitamin B2Tetracycline Antibiotics Moderate
Interaction Summary
Theoretically, taking riboflavin with tetracycline antibiotics may decrease the potency of these antibiotics.
Read the full Vitamin B2 + Oxytetracycline interactionOxytetracycline, Phenazopyridine, SulfamethizoleUrobiotic
How Oxytetracycline, Phenazopyridine, Sulfamethizole interacts with B2 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Vitamin B2Tetracycline Antibiotics Moderate
Interaction Summary
Theoretically, taking riboflavin with tetracycline antibiotics may decrease the potency of these antibiotics.
Read the full Vitamin B2 + Oxytetracycline, Phenazopyridine, Sulfamethizole interactionRetapamulinAltabax, Altargo
How Retapamulin interacts with B2 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Vitamin B2Tetracycline Antibiotics Moderate
Interaction Summary
Theoretically, taking riboflavin with tetracycline antibiotics may decrease the potency of these antibiotics.
Read the full Vitamin B2 + Retapamulin interactionTetracyclineAchromycin, Achromycin V, Nor-Tet, Robitet, Sumycin, Sumycin 250 +6 more
How Tetracycline interacts with B2 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Vitamin B2Tetracycline Antibiotics Moderate
Interaction Summary
Theoretically, taking riboflavin with tetracycline antibiotics may decrease the potency of these antibiotics.
Read the full Vitamin B2 + Tetracycline interactionTigecyclineTygacil
How Tigecycline interacts with B2 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Vitamin B2Tetracycline Antibiotics Moderate
Interaction Summary
Theoretically, taking riboflavin with tetracycline antibiotics may decrease the potency of these antibiotics.
Read the full Vitamin B2 + Tigecycline interactionEach ingredient & the kinds of drugs it affects
For each ingredient in B2 100 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Vitamin B2
Tetracycline Antibiotics
Theoretically, taking riboflavin with tetracycline antibiotics may decrease the potency of these antibiotics.
In vitro research suggests that riboflavin may inhibit the potency of tetracycline antibiotics. It is not clear if this effect is clinically significant, as this interaction has not been reported in humans.
Brand information
Manufacturer and brand details for B2 100 mg, from the product label.
Natural Grocers by Vitamin Cottage
See all Natural Grocers by Vitamin Cottage products- Name
- Vitamin Cottage Natural Food Markets, Inc.
- City
- Lakewood
- State
- CO
- ZipCode
- 80228
- Phone Number
- 877-455-2826
- Web Address
- www.naturalgrocers.com
B2 100 mg by Natural Grocers by Vitamin Cottage: Common Questions
Does B2 100 mg by Natural Grocers by Vitamin Cottage interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Will this cause nausea or upset my stomach?
Will my urine turn bright yellow?
Is it safe to take while pregnant or breastfeeding?
I take doxycycline for acne — can I use this?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if B2 100 mg is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind B2 100 mg’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
B2 100 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 5 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Riboflavin 5 references
- Schoenen J, Jacquy J, Lenaerts M. Effectiveness of high-dose riboflavin in migraine prophylaxis. A randomized controlled trial. Neurology 1998;50:466-70. PubMed
- Yates AA, Schlicker SA, Suitor CW. Dietary reference intakes: The new basis for recommendations for calcium and related nutrients, B vitamins, and choline. J Am Diet Assoc 1998;98:699-706. PubMed
- Leeson LJ, Weidenheimer JF. Stability of tetracycline and riboflavin. J Pharm Sci. 1969;58(3):355-7. PubMed
- MacLennan, S. C., Wade, F. M., Forrest, K. M., Ratanayake, P. D., Fagan, E., and Antony, J. High-dose riboflavin for migraine prophylaxis in children: a double-blind, randomized, placebo-controlled trial. J Child Neurol. 2008;23(11):1300-1304.
- Dietary reference intakes (DRIs): estimated average requirements. Food and Nutrition Board, Institute of Medicine, National Academics. https://www.nal.usda.gov/sites/default/files/fnic_uploads//recommended_intakes_individuals.pdf Accessed July 24, 2017.
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC