Interactions on record — worth a quick check against your medications. Based on 1 of 2 ingredients. Check your meds →
Dietary supplement

Baby Probiotic Drops Ingredients & Drug Interactions

by Culturelle Baby

Baby Probiotic Drops label
See full label image
Liquid Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 30, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Baby Probiotic Drops against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Baby Probiotic Drops is a dietary supplement by Culturelle Baby with 2 active ingredients. Its ingredients are commonly taken for digestive health and regularity, constipation relief, immune support.Based on those ingredients, 182 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Bifidobacterium animalis subsp. lactis. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Baby Probiotic Drops by Culturelle Baby

Ask about any prescription or over-the-counter medication and we check it for interactions with Baby Probiotic Drops by Culturelle Baby — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Baby Probiotic Drops by Culturelle Baby

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 16, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 2 active ingredients.
  • “Proprietary Blend Total Cultures” is a proprietary blend — the label doesn't break down how much of each component you get.

Culturelle Baby contains two active probiotic ingredients: Bifidobacterium animalis subsp. lactis and Lactobacillus rhamnosus GG. These are live, beneficial bacteria meant to support digestive and immune health in infants.

The product also contains inactive ingredients—rice bran oil, carnauba wax, sucrose, maltodextrin, and sodium ascorbate—that serve as carriers and preservatives for the live cultures.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: Digestive health and gut microbiome balance for infants.
  • We looked for evidence on: Antibiotic-associated diarrhea, Colic, Constipation, Malnourishment-related diarrhea, Necrotizing enterocolitis (NEC), Rotaviral diarrhea — and 3 related terms.
  • The strongest evidence on file: Bifidobacterium Animalis Subsp. Lactis is rated "Possibly Effective" for Constipation (Natural Medicines).
  • Also on file: Bifidobacterium Animalis Subsp. Lactis is rated "Possibly Effective" for Colic.
  • Also on file: Bifidobacterium Animalis Subsp. Lactis is rated "Insufficient Reliable Evidence To Rate" for Antibiotic-associated diarrhea, Malnourishment-related diarrhea, Necrotizing enterocolitis (NEC), Rotaviral diarrhea.

The data we hold shows that Bifidobacterium animalis subsp. lactis is possibly effective for respiratory tract infections, irritable bowel syndrome (IBS), and constipation. That means some research suggests it may help, but the evidence isn't conclusive yet.

We don't have effectiveness ratings for Lactobacillus rhamnosus GG in our data, so we can't speak to what it does.

The evidence, ingredient by ingredient Bifidobacterium Animalis Subsp. Lactis

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Bifidobacterium animalis subsp. lactis is generally well tolerated by most healthy people when taken as directed. The most commonly reported side effect is diarrhea.

Bloating, flatulence, stomach discomfort, and abdominal pain have been reported rarely. Very rarely, there's a theoretical concern that probiotics might cause infection in some people, though this is uncommon.

Since evidence in infants is limited, it's worth discussing this product with your pediatrician before starting. We don't have pregnancy or breastfeeding safety data on file for these ingredients.

Side effects, ingredient by ingredient Bifidobacterium Animalis Subsp. Lactis

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Bifidobacterium Animalis Subsp. Lactis.
  • The most serious interaction on file is rated Moderate.
  • For scale: 182 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If your baby takes antibiotic drugs, check the timing with your pharmacist—antibiotics can reduce how well this probiotic works if taken at the same time. Altogether, these interactions span 182 individual medications, so run your child's complete medication list through the checker on this page before starting.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Culturelle Baby Probiotic Drops may be worth considering if your pediatrician recommends probiotics for your infant's digestion or immune support. The main thing to watch: if your baby is on antibiotics, space out the doses to keep the antibiotics from killing the live cultures.

Talk with your pediatrician or pharmacist before starting, especially if your baby has any underlying health concerns or is taking other medications.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Apr 23, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Baby Probiotic Drops, straight from the product label.

Brand Culturelle Baby
Barcode (UPC) 049100400655
Net contents 0.3 Fluid Ounce(s); 9 mL
Market status On market
Date entered into DSLD Apr 23, 2020
DSLD ID 218195
Product type Non-nutrient/non-botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Infants/Baby (0 - 1 Year), Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Baby Probiotic Drops by Culturelle Baby, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Infants
Minimum serving Sizes:
5 Drop(s)
Maximum serving Sizes:
5 Drop(s)
Servings per container
30
UPC/BARCODE
049100400655
IngredientAmount% DV
Calories0 Calorie(s)--
Total Carbohydrates0 Gram(s)--
Added Sugars0 Gram(s)--
Total Sugars0 Gram(s)--
Lactobacillus rhamnosus GG0 NP--
Proprietary Blend Total Cultures0 NP--
Bifidobacterium animalis subsp. lactis0 NP--

Other ingredients: Rice Bran Oil, Carnauba Wax, Sucrose, Maltodextrin, Sodium Ascorbate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Precautions

Warning: Keep out of reach of children.

Inform a healthcare professional before starting any dietary supplement, particularly if there is a known immune-compromised condition.

If your infant develops an allergic reaction such as a rash, itching, wheezing or hives, discontinue use and call your doctor. When first taking a probiotic your baby's gut microbiom adjusts. Your baby may experience minor bloating, gas or intestinal gurgling which should subside with continued use. Consult your healthcare professional if symptoms continue after two weeks.

For questions, concerns or to report an adverse event, please call (800) 722-3476.

Tamper Evident: Do not use if bottle or dropper appears to be opened.

While there are no dairy-derived ingredients in this product, it is produced in a facility that also handles dairy ingredients.

Formulation

Contains none of the following: artificial dyes, preservatives, dairy, sugar, lactose, milk, yeast, soy or gluten.

Meets the FDA's guidelines for gluten-free.

Supports healthy development

Helps develop a healthy digestive system for better nutrient absorption Helps promote the development of a healthy immune system Supplements the good bacteria found in breast milk

Helps support a healthy immune system. Supplements good bacteria.

Storage

Storage Instructions: Store Culturelle in a cool, dry place away from direct sunlight. Guaranteed potency through date on box when stored as directed.

General Statements

For children over 1 year: Take Culturelle Baby Grow + Thrive Packets as directed on the package.

#1 Pediatrician recommended brand Based on a 2018 survey among pediatricians recommending a probiotic brand.

Formula

Contains sucrose which adds a dietarily insignificant amount of sugar. Not a reduced calorie food.

Probiotics

0-12 months

Help build a strong foundation for your baby with Culturelle Baby Probiotic Drops. Baby's first year is a critical period for the development of good bacteria that will shape their lifelong health. Give them safe and gentle Culturelle Baby Probiotic Drops with ingredients to help support this important phase in healthy development.

Contains the most clinically studied probiotic in infants, lacobacillus rhamnosus GG, to help support a healthy digestive and immune system. Based on the number of lactobacillus rhamnosus GGstudies, as of January 2018.

FDA Statement of Identity

Probiotic Supplement

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Suggested/Recommended/Usage/Directions

Directions for 0-12 Months: Use 5 drops once a day. Dispense directly into baby's mouth, bottle or while breastfeeding. Shake well before use. Before first use, replace cap with dropper and discard original cap. Washing of dropper in between use is not recommended. Once opened, use within 60 days.

Brand IP Statement(s)

Patent pending. Culturelle is a trademark of DSM. LGG, LGG logo and BB-12 are trademarks of Chr. Hansen A/S.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Baby Probiotic Drops by Culturelle Baby label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Baby Probiotic Drops label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Baby Probiotic Drops by Culturelle Baby

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size5 Drop(s) Dosage formLiquid Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Proprietary Blend Total Cultures

0 NP per serving

Other (inactive) ingredients: Rice Bran Oil, Carnauba Wax, Sucrose, Maltodextrin, Sodium Ascorbate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Baby Probiotic Drops by Culturelle Baby Drug Interactions

Want to check YOUR meds against Baby Probiotic Drops?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
182Drugs
182 Moderate

Ingredients driving the most interactions

Bifidobacterium animalis subsp. lactis 182

Individual Drug Interactions

The ingredients in Baby Probiotic Drops interact with 182 drugs. Click any drug to see the details.

1 of the 2 ingredients in Baby Probiotic Drops interact with drugs. Each result below shows which ingredient is responsible. Bifidobacterium animalis subsp. lactis

Each ingredient & the kinds of drugs it affects

For each ingredient in Baby Probiotic Drops with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Bifidobacterium animalis subsp. lactis1 drug type · 182 drugs

Antibiotic Drugs

Theoretically, taking Bifidobacterium lactis with antibiotic drugs might decrease the effectiveness of B. lactis.
Since B. lactis preparations usually contain live and active organisms, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and B. lactis preparations by at least 2 hours.

Likelihood Probable Evidence D
Bifidobacterium animalis subsp. lactis full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Baby Probiotic Drops, from the product label.

Culturelle Baby

See all Culturelle Baby products
Name
i-Health, Inc.
Street Address
55 Sebethe Drive
City
Cromwell
State
CT
ZipCode
06416
Phone Number
(800) 722-3476
Web Address
www.culturelle.com
Pharmacist Counseling Corner

Baby Probiotic Drops by Culturelle Baby: Common Questions

Does Baby Probiotic Drops by Culturelle Baby interact with any medications?
Yes. Based on its ingredients, Baby Probiotic Drops has a known interaction with 182 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Baby Probiotic Drops contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I give this to my baby if they're on antibiotics?
Yes, but timing matters. Antibiotics can kill the live bacteria in the probiotic, making it less effective. Ask your pharmacist to help you space out the doses—usually a few hours apart does the trick.
What side effects might my baby have?
Diarrhea is the most common side effect. Bloating, gas, stomach upset, and abdominal pain have been reported rarely. Most babies tolerate it well. If your baby has ongoing diarrhea or stomach pain, check in with your pediatrician.
Is this safe for newborns?
We don't have specific safety data on file for probiotics in newborns, so talk with your pediatrician first. They can advise whether this product is right for your baby's age and health.
How do I know if it's actually working?
Research suggests Bifidobacterium animalis subsp. lactis may help with constipation, respiratory infections, and irritable bowel syndrome, but the evidence isn't definitive. It may take a few weeks to notice any difference. Your pediatrician can help you track whether it's making a real difference for your baby.
What are the live cultures in this product?
The two active ingredients are Bifidobacterium animalis subsp. lactis and Lactobacillus rhamnosus GG—both are beneficial bacteria. The rest of the bottle is inactive ingredients like rice bran oil and carnauba wax that keep the cultures stable.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Baby Probiotic Drops is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Baby Probiotic Drops label
Go deeper

The Full Monographs Behind Baby Probiotic Drops’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Bifidobacterium Animalis Subsp. Lactis

Interacts with 182 drugs

Bifidobacterium animalis subsp. lactis is a well-studied probiotic bacterium commonly added to supplements and yogurts to support digestion and gut health. It appears generally safe for most...

Read the full Bifidobacterium Animalis Subsp. Lactis monograph →
Sources

Sources & How We Checked

Baby Probiotic Drops's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 8 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Bifidobacterium Animalis Subsp. Lactis 8 references
  1. Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
  2. Phuapradit P, Varavithya W, Vathanophas K, et al. Reduction of rotavirus infection in children receiving bifidobacteria-supplemented formula. J Med Assoc Thai 1999;82:S43-8.
  3. Xiao JZ, Takahashi S, Odamaki T, et al. Antibiotic susceptibility of bifidobacterial strains distributed in the Japanese market. Biosci Biotechnol Biochem. 2010;74(2):336-42. PubMed
  4. Begtrup LM, de Muckadell OB, Kjeldsen J, Christensen RD, Jarbøl DE. Long-term treatment with probiotics in primary care patients with irritable bowel syndrome--a randomised, double-blind, placebo controlled trial. Scand J Gastroenterol 2013;48(10):1127-35 PubMed
  5. Taipale TJ, Pienihäkkinen K, Isolauri E, Jokela JT, Söderling EM. Bifidobacterium animalis subsp. lactis BB-12 in reducing the risk of infections in early childhood. Pediatr Res. 2016;79(1-1):65-9. PubMed
  6. Amat-Bou M, Garcia-Ribera S, Climent E, et al. Effects of Bifidobacterium animalis Subsp. lactis (BPL1) supplementation in children and adolescents with prader-willi syndrome: A randomized crossover trial. Nutrients. 2020;12(10):3123. PubMed
  7. Mäkelä SM, Forssten SD, Kailajärvi M, et al. Effects of Bifidobacterium animalis ssp. lactis 420 on gastrointestinal inflammation induced by a nonsteroidal anti-inflammatory drug: A randomized, placebo-controlled, double-blind clinical trial. Br J Clin Ph
  8. Wildt S, Munck LK, Vinter-Jensen L, et al. Probiotic treatment of collagenous colitis: a randomized, double-blind, placebo-controlled trial with Lactobacillus acidophilus and Bifidobacterium animalis subsp. Lactis. Inflamm Bowel Dis 2006;12(5):395-401. PubMed

See these in context on the Bifidobacterium Animalis Subsp. Lactis monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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