Interactions on record — worth a quick check against your medications. Based on 1 of 2 ingredients. Check your meds →
Dietary supplement

Basis Ingredients & Drug Interactions

by Elysium

Capsule Category: Other Combinations
Most serious interaction: Minor
The interaction bottom line Most serious interaction: Minor

Basis is a dietary supplement by Elysium with 2 active ingredients. Its ingredients are commonly taken for healthy aging, boosting cellular energy, supporting metabolism.Based on those ingredients, 172 medications have a known interaction with it, the most serious rated minor. The ingredients most likely to interact are Nicotinamide Riboside. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Basis by Elysium

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

Basis contains two active ingredients: nicotinamide riboside and pterostilbene. Nicotinamide riboside is a form of vitamin B3 that your cells use to make NAD+, a coenzyme involved in energy production and cellular repair.

Pterostilbene is a compound found in plants; we don't hold detailed information on its intended role in this formula. The capsule also contains inactive ingredients: microcrystalline cellulose, hypromellose, vegetable magnesium stearate, and silica — these are fillers and binders that give the capsule its form.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

We hold no graded evidence for this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: Metabolic repair and optimization.
  • We looked for evidence on: Metabolic health, Cellular energy metabolism, NAD+ metabolism.
  • Our graded evidence for these ingredients doesn't cover that particular purpose.

The evidence for nicotinamide riboside in the conditions Basis is marketed for — age-related macular degeneration, Alzheimer disease, athletic performance, nonalcoholic fatty liver disease, and heart failure — is rated as insufficient reliable evidence in our data. That means studies to date haven't established whether it works for these purposes.

We also hold no effectiveness data for pterostilbene.

The evidence, ingredient by ingredient Nicotinamide Riboside

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Nicotinamide riboside appears generally well tolerated in short-term studies, though long-term safety isn't fully known. The most commonly reported side effects in trials were bloating, muscle pain, nausea, itching, sweating, and changes in bowel habits.

Stomach upset, diarrhea, and abdominal discomfort have been reported with Basis itself, though it's unclear whether these came from nicotinamide riboside, pterostilbene, or the combination. Leg cramps were reported in one patient in a separate trial.

There isn't enough safety data to know either way about nicotinamide riboside in pregnancy or while breastfeeding — talk with your doctor or pharmacist for personalized advice if you're pregnant, planning to become pregnant, or breastfeeding.

Side effects, ingredient by ingredient Nicotinamide Riboside

Meds to double-check

Minor interactions only
Known Interaction Concern · database check
Minor only

Only Minor-severity interactions are documented for these ingredients.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Nicotinamide Riboside.
  • The most serious interaction on file is rated Minor.
  • For scale: 172 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take blood pressure–lowering drugs (antihypertensives), check with your doctor or pharmacist before adding Basis — nicotinamide riboside may have additive effects and increase the risk for low blood pressure, though this is a Minor severity interaction. We could not check pterostilbene for interactions with any medications.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Only minor medication interactions are documented, and safety information is well characterized.

Basis is marketed for age-related vision decline, brain health, athletic performance, liver health, and heart function, but the evidence for nicotinamide riboside in these areas is insufficient. If you take blood pressure medication, check your exact drugs with your own doctor or pharmacist before starting, since nicotinamide riboside may lower blood pressure further.

The supplement appears tolerable in short-term use, though long-term safety is still being studied.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Aug 23, 2019.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Basis, straight from the product label.

Brand Elysium
Net contents 60 Capsule(s)
Market status On market
Date entered into DSLD Aug 23, 2019
DSLD ID 205969
Product type Other Combinations
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Basis by Elysium, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Vegetarian Capsule(s)
Maximum serving Sizes:
2 Vegetarian Capsule(s)
Servings per container
30
IngredientAmount% DV
Pterostilbene50 mg--
Nicotinamide Riboside250 mg--

Other ingredients: Microcrystalline Cellulose, Hypromellose, Vegetable Magnesium Stearate, Silica

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Metabolic Repair & Optimization

FDA Statement of Identity

Dietary Supplement

Brand IP Statement(s)

Protected under U.S. Patent Numbers: 8,197,807 / 8,383,086 / 8,524,782 / 8,133,917 / 8,252,845 Elysium Health is a trademark of Elysium Health LLC

Suggested/Recommended/Usage/Directions

Suggested use: Take two (2) vegetarian capsules daily as a dietary supplement or as recommended by your healthcare professional.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Precautions

Warning: This product is intended for healthy adults, 18 years of age or older.

Do not take this product if you are pregnant or nursing.

Consult with a licensed, qualified, healthcare professional before using this or any dietary supplement product.

Keep out of reach of children.

Tamper resistant: Do not use if imprinted safety seal under cap is broken or missing.

Storage

Store bottle tightly closed in a cool, dry place.

See for yourself

Basis by Elysium label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Basis by Elysium

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 Vegetarian Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Pterostilbene

50 mg per serving

Nicotinamide Riboside

Interacts with
172 drugs
250 mg per serving

Nicotinamide riboside (NR) is a form of vitamin B3 that the body converts into NAD+, a molecule involved in cellular energy and repair. Early human st...

Nicotinamide Riboside monograph & interactions

Other (inactive) ingredients: Microcrystalline Cellulose, Hypromellose, Vegetable Magnesium Stearate, Silica. These complete the product’s ingredient list but are not active constituents.

Interaction report

Basis by Elysium Drug Interactions

Want to check YOUR meds against Basis?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
172Drugs
172 Minor

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Basis with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Nicotinamide Riboside1 drug type · 172 drugs

Antihypertensive Drugs

Theoretically, nicotinamide riboside may have additive effects with antihypertensive drugs, potentially increasing the risk for hypotension.
One small clinical study suggests that nicotinamide riboside can modestly reduce blood pressure in hypertensive patients. However, other clinical research did not find a reduction in blood pressure when compared with control.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Basis, from the product label.

Elysium

See all Elysium products
Name
Elysium Health LLC
City
Delray Beach
State
FL
ZipCode
33445
Phone Number
1-888-220-6436
Web Address
www.elysiumhealth.com
Pharmacist Counseling Corner

Basis by Elysium: Common Questions

Does Basis by Elysium interact with any medications?
Yes. Based on its ingredients, Basis has a known interaction with 172 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Basis contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take Basis if I'm pregnant or breastfeeding?
There isn't enough safety data to know whether nicotinamide riboside is safe during pregnancy or while breastfeeding. Talk with your doctor or pharmacist if you're pregnant, planning to become pregnant, or nursing — they can help you decide what's right for you.
What side effects might I experience?
The most common ones reported in trials were bloating, muscle pain, nausea, itching, sweating, and changes in bowel habits. Stomach upset, diarrhea, and abdominal discomfort have also been reported with Basis. Nicotinamide riboside generally appears well tolerated, but side effects vary from person to person.
Does Basis actually work for anti-aging or brain health?
The evidence for nicotinamide riboside in age-related vision problems, Alzheimer disease, athletic performance, liver health, and heart function is rated as insufficient — meaning studies haven't yet established whether it works for these purposes.
What is nicotinamide riboside?
It's a form of vitamin B3 that your cells use to make NAD+, a molecule involved in energy production and cellular repair. That's the theory behind why it might support aging and health — but the evidence for specific conditions isn't strong enough yet.
What does pterostilbene do?
Pterostilbene is a compound found in plants — it's included in Basis as a second active ingredient, though we don't hold detailed information on its intended role in this formula.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Basis is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Basis label
Sources

Sources & How We Checked

Basis's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 7 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Nicotinamide Riboside 7 references
  1. Martens CR, Denman BA, Mazzo MR, et al. Chronic nicotinamide riboside supplementation is well-tolerated and elevates NAD+ in healthy middle-aged and older adults. Nat Commun 2018;9(1):1286. PubMed
  2. Dollerup OL, Christensen B, Svart M, et al. A randomized placebo-controlled clinical trial of nicotinamide riboside in obese men: safety, insulin-sensitivity, and lipid-mobilizing effects. Am J Clin Nutr 2018;108(2):343-53. PubMed
  3. Dellinger RW, Santos SR, Morris M, et al. Repeat dose NRPT (nicotinamide riboside and pterostilbene) increases NAD+ levels in humans safety and sustainably: a randomized, double-blind, placebo-controlled study. NPJ J Aging Mech Dis 2017;3:17.
  4. Conze D, Brenner C, Kruger CL. Safety and metabolism of long-term administration of NIAGEN (nicotinamide riboside chloride) in a randomized, double-blind, placebo-controlled clinical trial of healthy overweight adults. Sci Rep 2019;9(1):9772. PubMed
  5. Remie CME, Roumans KHM, Moonen MPB, et al. Nicotinamide riboside supplementation alters body composition and skeletal muscle acetylcarnitine concentrations in healthy obese humans. Am J Clin Nutr. 2020;112(2):413-426. PubMed
  6. Turck D, Castenmiller J, de Henauw S, et al. Safety of nicotinamide riboside chloride as a novel food pursuant to Regulation (EU) 2015/2283 and bioavailability of nicotinamide from this source, in the context of Directive 2002/46/EC. EFSA J. 2019;17(8):e0
  7. EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA), Turck D, et al. Extension of use of nicotinamide riboside chloride as a novel food pursuant to Regulation (EU) 2015/2283. EFSA J 2021;19(11):e06843.

See these in context on the Nicotinamide Riboside monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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