Basis Ingredients & Drug Interactions
by Elysium
What is this page for?
First and foremost: checking Basis against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Basis is a dietary supplement by Elysium with 2 active ingredients. Its ingredients are commonly taken for healthy aging, boosting cellular energy, supporting metabolism.Based on those ingredients, 172 medications have a known interaction with it, the most serious rated minor. The ingredients most likely to interact are Nicotinamide Riboside. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Basis by Elysium
Ask about any prescription or over-the-counter medication and we check it for interactions with Basis by Elysium — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Basis by Elysium
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
Basis contains two active ingredients: nicotinamide riboside and pterostilbene. The product also includes several inactive ingredients — microcrystalline cellulose, hypromellose, vegetable magnesium stearate, and silica — which serve as fillers and capsule materials.
Does it work?
Couldn't assess
The evidence for nicotinamide riboside isn't established in our data for any of the conditions this product may be marketed for — including age-related macular degeneration, Alzheimer disease, athletic performance, fatty liver disease, and heart failure. Each is rated as having insufficient reliable evidence to rate.
That doesn't mean it doesn't work; it means the studies aren't yet strong enough to say one way or the other.
How safe is it?
Well-documented data
Nicotinamide riboside appears generally well tolerated in short-term studies, though long-term safety isn't fully known. The most common side effects reported in trials are bloating, muscle pain, nausea, itching, sweating, and temporary changes in bowel movements.
A few patients have reported mild nausea, bloating, abdominal discomfort, diarrhea, indigestion, or leg cramps, though it's unclear whether these came from nicotinamide riboside, pterostilbene, or the combination. There isn't enough safety data during pregnancy or while breastfeeding to know whether Basis is safe — the safety data advises against use in both.
Talk with your doctor or pharmacist before taking it if you're pregnant or nursing.
Meds to double-check
Minor interactions only
If you take antihypertensive drugs (blood-pressure medications), nicotinamide riboside in this product may add to their effect and lower your blood pressure further. Check your exact medications with your doctor or pharmacist before taking Basis.
The bottom line
Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Only minor medication interactions are documented, and safety information is well characterized.
Basis may be worth considering if you're interested in supporting cellular energy and aging-related health, but the evidence for these benefits hasn't yet been firmly established. If you take blood-pressure medication, check it with your pharmacist or doctor before starting.
The long-term safety profile isn't completely known, so this is a good conversation to have with your healthcare provider.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jul 21, 2022.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Basis, straight from the product label.
| Brand | Elysium |
|---|---|
| Net contents | 60 Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Jul 21, 2022 |
| DSLD ID | 270933 |
| Product type | Other Combinations |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Women (not pregnant or lactating) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Basis by Elysium, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Pterostilbene | 50 mg | -- |
| Nicotinamide Riboside | 250 mg | -- |
Other ingredients: Microcrystalline Cellulose, Hypromellose, Vegetable Magnesium Stearate, Silica
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Suggested Use: Take two (2) capsules every morning with or without food.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Precautions
Warning: This product is only intended for healthy adults.
Do not take this product if you are pregnant or nursing.
Consult with your physician before using.
Keep out of reach of children.
Do not use if safety seal is broken or missing.
Storage
Store bottle tightly closed in a cool, dry place.
Formulation
Cellular health & optimization
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Basis by Elysium label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Basis by Elysium
These are the 2 active ingredients this product is made of. Select any to open its full monograph.
Serving size2 Vegetarian Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Pterostilbene
Nicotinamide Riboside
Interacts with172 drugs
Nicotinamide riboside (NR) is a form of vitamin B3 that the body converts into NAD+, a molecule involved in cellular energy and repair. Early human st...
Nicotinamide Riboside monograph & interactionsOther (inactive) ingredients: Microcrystalline Cellulose, Hypromellose, Vegetable Magnesium Stearate, Silica. These complete the product’s ingredient list but are not active constituents.
Basis by Elysium Drug Interactions
HelloPharmacist Interaction Report
Basis by Elysium contains nicotinamide riboside, which has one documented drug interaction.
Nicotinamide riboside may add to the blood-pressure-lowering effect of antihypertensive drugs (medications used to treat high blood pressure), which could theoretically increase the risk of low blood pressure (hypotension). One small clinical study suggests nicotinamide riboside can modestly lower blood pressure on its own, though other research did not find this effect.
Read the full breakdown — every affected drug type, severity by severity
We could not check the other active ingredient, pterostilbene, because we hold no interaction data for it.
Altogether, these interactions span 172 individual medications. If you take any blood-pressure medication, check your exact drugs with the tool below before starting Basis.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Basis?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Basis interact with 172 drugs. Click any drug to see the details.
1 of the 2 ingredients in Basis interact with drugs. Each result below shows which ingredient is responsible. Nicotinamide Riboside
AcebutololRhotral, Sectral
How Acebutolol interacts with Basis — through 1 ingredient. Tap an ingredient for the detail:
Nicotinamide RibosideAntihypertensive Drugs Minor
Interaction Summary
Theoretically, nicotinamide riboside may have additive effects with antihypertensive drugs, potentially increasing the risk for hypotension.
Read the full Nicotinamide Riboside + Acebutolol interactionAcetazolamideAk-Zol, Diamox
How Acetazolamide interacts with Basis — through 1 ingredient. Tap an ingredient for the detail:
Nicotinamide RibosideAntihypertensive Drugs Minor
Interaction Summary
Theoretically, nicotinamide riboside may have additive effects with antihypertensive drugs, potentially increasing the risk for hypotension.
Read the full Nicotinamide Riboside + Acetazolamide interactionAliskirenTekturna
How Aliskiren interacts with Basis — through 1 ingredient. Tap an ingredient for the detail:
Nicotinamide RibosideAntihypertensive Drugs Minor
Interaction Summary
Theoretically, nicotinamide riboside may have additive effects with antihypertensive drugs, potentially increasing the risk for hypotension.
Read the full Nicotinamide Riboside + Aliskiren interactionAmbrisentanLetairis, Volibris
How Ambrisentan interacts with Basis — through 1 ingredient. Tap an ingredient for the detail:
Nicotinamide RibosideAntihypertensive Drugs Minor
Interaction Summary
Theoretically, nicotinamide riboside may have additive effects with antihypertensive drugs, potentially increasing the risk for hypotension.
Read the full Nicotinamide Riboside + Ambrisentan interactionAmilorideAmilamont, Midamor
How Amiloride interacts with Basis — through 1 ingredient. Tap an ingredient for the detail:
Nicotinamide RibosideAntihypertensive Drugs Minor
Interaction Summary
Theoretically, nicotinamide riboside may have additive effects with antihypertensive drugs, potentially increasing the risk for hypotension.
Read the full Nicotinamide Riboside + Amiloride interactionAmiloride, HydrochlorothiazideAmil-Co, Amilzide, Moduret 25, Moduretic
How Amiloride, Hydrochlorothiazide interacts with Basis — through 1 ingredient. Tap an ingredient for the detail:
Nicotinamide RibosideAntihypertensive Drugs Minor
Interaction Summary
Theoretically, nicotinamide riboside may have additive effects with antihypertensive drugs, potentially increasing the risk for hypotension.
Read the full Nicotinamide Riboside + Amiloride, Hydrochlorothiazide interactionAmlodipineNorliqva
How Amlodipine interacts with Basis — through 1 ingredient. Tap an ingredient for the detail:
Nicotinamide RibosideAntihypertensive Drugs Minor
Interaction Summary
Theoretically, nicotinamide riboside may have additive effects with antihypertensive drugs, potentially increasing the risk for hypotension.
Read the full Nicotinamide Riboside + Amlodipine interactionAmlodipine BenzoateKaterzia
How Amlodipine Benzoate interacts with Basis — through 1 ingredient. Tap an ingredient for the detail:
Nicotinamide RibosideAntihypertensive Drugs Minor
Interaction Summary
Theoretically, nicotinamide riboside may have additive effects with antihypertensive drugs, potentially increasing the risk for hypotension.
Read the full Nicotinamide Riboside + Amlodipine Benzoate interactionAmlodipine BesilateIstin
How Amlodipine Besilate interacts with Basis — through 1 ingredient. Tap an ingredient for the detail:
Nicotinamide RibosideAntihypertensive Drugs Minor
Interaction Summary
Theoretically, nicotinamide riboside may have additive effects with antihypertensive drugs, potentially increasing the risk for hypotension.
Read the full Nicotinamide Riboside + Amlodipine Besilate interactionAmlodipine BesylateNorvasc
How Amlodipine Besylate interacts with Basis — through 1 ingredient. Tap an ingredient for the detail:
Nicotinamide RibosideAntihypertensive Drugs Minor
Interaction Summary
Theoretically, nicotinamide riboside may have additive effects with antihypertensive drugs, potentially increasing the risk for hypotension.
Read the full Nicotinamide Riboside + Amlodipine Besylate interactionAmlodipine Besylate, BenazeprilLotrel
How Amlodipine Besylate, Benazepril interacts with Basis — through 1 ingredient. Tap an ingredient for the detail:
Nicotinamide RibosideAntihypertensive Drugs Minor
Interaction Summary
Theoretically, nicotinamide riboside may have additive effects with antihypertensive drugs, potentially increasing the risk for hypotension.
Read the full Nicotinamide Riboside + Amlodipine Besylate, Benazepril interactionAmlodipine, CelecoxibConsensi
How Amlodipine, Celecoxib interacts with Basis — through 1 ingredient. Tap an ingredient for the detail:
Nicotinamide RibosideAntihypertensive Drugs Minor
Interaction Summary
Theoretically, nicotinamide riboside may have additive effects with antihypertensive drugs, potentially increasing the risk for hypotension.
Read the full Nicotinamide Riboside + Amlodipine, Celecoxib interactionAmmonium ChlorideAmmonium Chloride
How Ammonium Chloride interacts with Basis — through 1 ingredient. Tap an ingredient for the detail:
Nicotinamide RibosideAntihypertensive Drugs Minor
Interaction Summary
Theoretically, nicotinamide riboside may have additive effects with antihypertensive drugs, potentially increasing the risk for hypotension.
Read the full Nicotinamide Riboside + Ammonium Chloride interactionAprocitentanTryvio
How Aprocitentan interacts with Basis — through 1 ingredient. Tap an ingredient for the detail:
Nicotinamide RibosideAntihypertensive Drugs Minor
Interaction Summary
Theoretically, nicotinamide riboside may have additive effects with antihypertensive drugs, potentially increasing the risk for hypotension.
Read the full Nicotinamide Riboside + Aprocitentan interactionAtenololAtenix, Tenormin
How Atenolol interacts with Basis — through 1 ingredient. Tap an ingredient for the detail:
Nicotinamide RibosideAntihypertensive Drugs Minor
Interaction Summary
Theoretically, nicotinamide riboside may have additive effects with antihypertensive drugs, potentially increasing the risk for hypotension.
Read the full Nicotinamide Riboside + Atenolol interactionAtenolol, ChlortalidoneAtenixCo, Tenoret 50, Totaretic
How Atenolol, Chlortalidone interacts with Basis — through 1 ingredient. Tap an ingredient for the detail:
Nicotinamide RibosideAntihypertensive Drugs Minor
Interaction Summary
Theoretically, nicotinamide riboside may have additive effects with antihypertensive drugs, potentially increasing the risk for hypotension.
Read the full Nicotinamide Riboside + Atenolol, Chlortalidone interactionAtenolol, ChlorthalidoneTenoretic
How Atenolol, Chlorthalidone interacts with Basis — through 1 ingredient. Tap an ingredient for the detail:
Nicotinamide RibosideAntihypertensive Drugs Minor
Interaction Summary
Theoretically, nicotinamide riboside may have additive effects with antihypertensive drugs, potentially increasing the risk for hypotension.
Read the full Nicotinamide Riboside + Atenolol, Chlorthalidone interactionAzilsartanEdarbi
How Azilsartan interacts with Basis — through 1 ingredient. Tap an ingredient for the detail:
Nicotinamide RibosideAntihypertensive Drugs Minor
Interaction Summary
Theoretically, nicotinamide riboside may have additive effects with antihypertensive drugs, potentially increasing the risk for hypotension.
Read the full Nicotinamide Riboside + Azilsartan interactionAzilsartan, ChlorthalidoneEdarbyclor
How Azilsartan, Chlorthalidone interacts with Basis — through 1 ingredient. Tap an ingredient for the detail:
Nicotinamide RibosideAntihypertensive Drugs Minor
Interaction Summary
Theoretically, nicotinamide riboside may have additive effects with antihypertensive drugs, potentially increasing the risk for hypotension.
Read the full Nicotinamide Riboside + Azilsartan, Chlorthalidone interactionBenazeprilLotensin
How Benazepril interacts with Basis — through 1 ingredient. Tap an ingredient for the detail:
Nicotinamide RibosideAntihypertensive Drugs Minor
Interaction Summary
Theoretically, nicotinamide riboside may have additive effects with antihypertensive drugs, potentially increasing the risk for hypotension.
Read the full Nicotinamide Riboside + Benazepril interactionBenazepril, HydrochlorothiazideLotensin HCT
How Benazepril, Hydrochlorothiazide interacts with Basis — through 1 ingredient. Tap an ingredient for the detail:
Nicotinamide RibosideAntihypertensive Drugs Minor
Interaction Summary
Theoretically, nicotinamide riboside may have additive effects with antihypertensive drugs, potentially increasing the risk for hypotension.
Read the full Nicotinamide Riboside + Benazepril, Hydrochlorothiazide interactionBendroflumethiazideAprinox, Naturetin, Neo-NaClex
How Bendroflumethiazide interacts with Basis — through 1 ingredient. Tap an ingredient for the detail:
Nicotinamide RibosideAntihypertensive Drugs Minor
Interaction Summary
Theoretically, nicotinamide riboside may have additive effects with antihypertensive drugs, potentially increasing the risk for hypotension.
Read the full Nicotinamide Riboside + Bendroflumethiazide interactionBendroflumethiazide, NadololCorzide
How Bendroflumethiazide, Nadolol interacts with Basis — through 1 ingredient. Tap an ingredient for the detail:
Nicotinamide RibosideAntihypertensive Drugs Minor
Interaction Summary
Theoretically, nicotinamide riboside may have additive effects with antihypertensive drugs, potentially increasing the risk for hypotension.
Read the full Nicotinamide Riboside + Bendroflumethiazide, Nadolol interactionBendroflumethiazide, Rauwolfia SerpentinaRauzide
How Bendroflumethiazide, Rauwolfia Serpentina interacts with Basis — through 1 ingredient. Tap an ingredient for the detail:
Nicotinamide RibosideAntihypertensive Drugs Minor
Interaction Summary
Theoretically, nicotinamide riboside may have additive effects with antihypertensive drugs, potentially increasing the risk for hypotension.
Read the full Nicotinamide Riboside + Bendroflumethiazide, Rauwolfia Serpentina interactionBenzthiazideExna
How Benzthiazide interacts with Basis — through 1 ingredient. Tap an ingredient for the detail:
Nicotinamide RibosideAntihypertensive Drugs Minor
Interaction Summary
Theoretically, nicotinamide riboside may have additive effects with antihypertensive drugs, potentially increasing the risk for hypotension.
Read the full Nicotinamide Riboside + Benzthiazide interactionBetaxololBetoptic, Kerlone
How Betaxolol interacts with Basis — through 1 ingredient. Tap an ingredient for the detail:
Nicotinamide RibosideAntihypertensive Drugs Minor
Interaction Summary
Theoretically, nicotinamide riboside may have additive effects with antihypertensive drugs, potentially increasing the risk for hypotension.
Read the full Nicotinamide Riboside + Betaxolol interactionBisoprololZebeta
How Bisoprolol interacts with Basis — through 1 ingredient. Tap an ingredient for the detail:
Nicotinamide RibosideAntihypertensive Drugs Minor
Interaction Summary
Theoretically, nicotinamide riboside may have additive effects with antihypertensive drugs, potentially increasing the risk for hypotension.
Read the full Nicotinamide Riboside + Bisoprolol interactionBisoprolol, HydrochlorothiazideZiac
How Bisoprolol, Hydrochlorothiazide interacts with Basis — through 1 ingredient. Tap an ingredient for the detail:
Nicotinamide RibosideAntihypertensive Drugs Minor
Interaction Summary
Theoretically, nicotinamide riboside may have additive effects with antihypertensive drugs, potentially increasing the risk for hypotension.
Read the full Nicotinamide Riboside + Bisoprolol, Hydrochlorothiazide interactionBosentanTracleer
How Bosentan interacts with Basis — through 1 ingredient. Tap an ingredient for the detail:
Nicotinamide RibosideAntihypertensive Drugs Minor
Interaction Summary
Theoretically, nicotinamide riboside may have additive effects with antihypertensive drugs, potentially increasing the risk for hypotension.
Read the full Nicotinamide Riboside + Bosentan interactionBumetanideBurinex
How Bumetanide interacts with Basis — through 1 ingredient. Tap an ingredient for the detail:
Nicotinamide RibosideAntihypertensive Drugs Minor
Interaction Summary
Theoretically, nicotinamide riboside may have additive effects with antihypertensive drugs, potentially increasing the risk for hypotension.
Read the full Nicotinamide Riboside + Bumetanide interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Basis with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Nicotinamide Riboside
Antihypertensive Drugs
Theoretically, nicotinamide riboside may have additive effects with antihypertensive drugs, potentially increasing the risk for hypotension.
One small clinical study suggests that nicotinamide riboside can modestly reduce blood pressure in hypertensive patients. However, other clinical research did not find a reduction in blood pressure when compared with control.
Brand information
Manufacturer and brand details for Basis, from the product label.
Basis by Elysium: Common Questions
Does Basis by Elysium interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
What does nicotinamide riboside actually do?
What's pterostilbene?
What side effects might I experience?
Is it safe to take while pregnant or breastfeeding?
How long can I safely take this?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Basis is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Basis’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Basis's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 7 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Nicotinamide Riboside 7 references
- Martens CR, Denman BA, Mazzo MR, et al. Chronic nicotinamide riboside supplementation is well-tolerated and elevates NAD+ in healthy middle-aged and older adults. Nat Commun 2018;9(1):1286. PubMed
- Dollerup OL, Christensen B, Svart M, et al. A randomized placebo-controlled clinical trial of nicotinamide riboside in obese men: safety, insulin-sensitivity, and lipid-mobilizing effects. Am J Clin Nutr 2018;108(2):343-53. PubMed
- Dellinger RW, Santos SR, Morris M, et al. Repeat dose NRPT (nicotinamide riboside and pterostilbene) increases NAD+ levels in humans safety and sustainably: a randomized, double-blind, placebo-controlled study. NPJ J Aging Mech Dis 2017;3:17.
- Conze D, Brenner C, Kruger CL. Safety and metabolism of long-term administration of NIAGEN (nicotinamide riboside chloride) in a randomized, double-blind, placebo-controlled clinical trial of healthy overweight adults. Sci Rep 2019;9(1):9772. PubMed
- Remie CME, Roumans KHM, Moonen MPB, et al. Nicotinamide riboside supplementation alters body composition and skeletal muscle acetylcarnitine concentrations in healthy obese humans. Am J Clin Nutr. 2020;112(2):413-426. PubMed
- Turck D, Castenmiller J, de Henauw S, et al. Safety of nicotinamide riboside chloride as a novel food pursuant to Regulation (EU) 2015/2283 and bioavailability of nicotinamide from this source, in the context of Directive 2002/46/EC. EFSA J. 2019;17(8):e0
- EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA), Turck D, et al. Extension of use of nicotinamide riboside chloride as a novel food pursuant to Regulation (EU) 2015/2283. EFSA J 2021;19(11):e06843.
See these in context on the Nicotinamide Riboside monograph →
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC