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Dietary supplement

Beet Juice 500 mg Ingredients & Drug Interactions

by Swanson

Beet Juice 500 mg label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Beet Juice 500 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Beet Juice 500 mg is a dietary supplement by Swanson with 1 active ingredient. Its ingredients are commonly taken for high blood pressure, exercise and athletic performance, heart and circulation support.Based on those ingredients, 861 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are organic Beet Juice. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Beet Juice 500 mg by Swanson

Ask about any prescription or over-the-counter medication and we check it for interactions with Beet Juice 500 mg by Swanson — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Beet Juice 500 mg by Swanson

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 12, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: organic beet juice at 500 mg per capsule. Beet juice is the concentrated form of beetroot, which supplies betanin (the pigment that gives beets their deep red color) and nitrates — compounds your body converts to nitric oxide, a signaling molecule involved in blood vessel function and exercise response.

The capsule also contains inactive ingredients: pullulan (a plant-based capsule material), silica (an anti-caking agent), magnesium stearate (a lubricant), and rice flour (a filler).

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: nitric oxide production and blood circulation.
  • We looked for evidence on: Hypertension, Pregnancy-induced hypertension, Coronary heart disease (CHD), Athletic performance, Exercise-induced muscle damage, Exercise-induced muscle soreness — and 4 related terms.
  • The strongest evidence on file: Beet is rated "Possibly Effective" for Athletic performance (Natural Medicines).
  • Also on file: Beet is rated "Possibly Effective" for Exercise-induced muscle soreness.
  • Also on file: Beet is rated "Insufficient Reliable Evidence To Rate" for Coronary heart disease (CHD), Hypertension, Pregnancy-induced hypertension, Raynaud syndrome, and more.

Beet juice is possibly effective for athletic performance and for easing exercise-induced muscle soreness — the soreness you feel 24 to 72 hours after a hard workout. For other uses, the evidence is less clear.

It's rated possibly ineffective for chronic obstructive pulmonary disease (COPD), and we don't hold enough reliable evidence to rate it for high cholesterol levels (dyslipidemia) or cognitive function.

The evidence, ingredient by ingredient Beet

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Beet is a food eaten safely by many people, and short-term use of beet supplements appears well tolerated by most adults. That said, concentrated beet supplements lack the long-term safety data we have for beet as a food, so use them with caution if you're planning to take them regularly.

Common side effects are harmless: red or dark stools and red urine — the pigment passing through. In rare cases, very large amounts of beet have been linked to low blood calcium (hypocalcemia) and kidney damage.

One case report described black stools and mild gastrointestinal symptoms in an older person taking beet pills while also on blood thinners, though bleeding risk was deemed low. Pregnancy and lactation safety data for concentrated beet supplements are not on file — talk to your doctor or pharmacist if you're pregnant or nursing.

Side effects, ingredient by ingredient Beet

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Beet.
  • The most serious interaction on file is rated Moderate.
  • For scale: 862 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, double-check your medications against the search tool on this page. The biggest concerns are drugs processed by CYP3A4 (a liver enzyme) — beet may raise their blood levels — and drugs processed by CYP1A2 — beet may lower their levels.

Also mention blood pressure medications to your pharmacist, since beet contains nitrates that can relax blood vessels.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

If you're an athlete or active person looking to boost endurance or reduce muscle soreness after workouts, beet juice is possibly worth trying. But if you take any prescription medication — especially drugs broken down by your liver — check with us or your pharmacist first, since beet can alter how your body processes many common drugs.

It's generally well tolerated for short-term use, though concentrated supplements are less studied than beet as a food.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Sep 21, 2018.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Beet Juice 500 mg, straight from the product label.

Brand Swanson
Barcode (UPC) 087614028149
Net contents 60 Veggie Capsule(s)
Market status On market
Date entered into DSLD Sep 21, 2018
DSLD ID 180932
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Organic
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Beet Juice 500 mg by Swanson, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Veggie Capsule(s)
Maximum serving Sizes:
1 Veggie Capsule(s)
UPC/BARCODE
087614028149
IngredientAmount% DV
organic Beet Juice500 mg--

Other ingredients: Pullulan, Silica, Magnesium Stearate, Rice Flour

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Promotes nitric oxide production Maintains healthy blood circulation Promotes energy production Science-Backed Quality Since 1969

Suggested use: As a dietary supplement, take one veggie capsule one to two times per day with water.

Cardiovascular Health

Precautions

Warning: For adults only.

Consult your physician before using this or any product if you are pregnant or nursing, taking medication or have a medical condition.

Keep out of reach of children.

Do not use if seal is broken.

Storage

Store in a cool, dry place.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Formula

Made with organic beets

FDA Statement of Identity

Dietary Supplement

Formulation

Certified Organic by Minnesota Crop Improvement Association (MCIA), St. Paul, MN 55108.

General

SWU814 Rev 0 02 14 18

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Beet Juice 500 mg by Swanson label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Beet Juice 500 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Beet Juice 500 mg by Swanson

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Veggie Capsule(s) Dosage formCapsule Amounts shown are per serving.

Organic Beet Juice

Interacts with
861 drugs
500 mg per serving

Beet, especially beetroot juice, is a nitrate-rich food that may modestly lower blood pressure and slightly improve exercise performance in some peopl...

Organic Beet Juice monograph & interactions

Other (inactive) ingredients: Pullulan, Silica, Magnesium Stearate, Rice Flour. These complete the product’s ingredient list but are not active constituents.

Interaction report

Beet Juice 500 mg by Swanson Drug Interactions

Want to check YOUR meds against Beet Juice 500 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
861Drugs
643 Moderate 218 Minor

Ingredients driving the most interactions

organic Beet Juice 861

Individual Drug Interactions

The ingredients in Beet Juice 500 mg interact with 861 drugs. Click any drug to see the details.

1 of the 1 ingredient in Beet Juice 500 mg interact with drugs. Each result below shows which ingredient is responsible. organic Beet Juice

Each ingredient & the kinds of drugs it affects

For each ingredient in Beet Juice 500 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

organic Beet Juice3 drug types · 861 drugs

Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, beet might increase the levels of CYP3A4 substrates.
In vitro research suggests that betanin, the major pigment in beet, competitively inhibits CYP3A4 in a dose-dependent manner similarly to strong CYP3A4 inhibitor ketoconazole.

Likelihood Possible Evidence D
Antihypertensive Drugs

Beet and beetroot contain nitrates, which can cause vasodilation, potentially leading to lower blood pressure. However, a study published in the European Journal of Clinical Nutrition using concentrated beetroot juice found no significant impact on blood pressure or heart rate in different age groups. Other small clinical studies suggest that while beet consumption might transiently lower blood pressure due to vessel dilation, there's no consistent evidence of a lasting effect. Overall, the theoretical risk of reduced blood pressure due to beet's nitrate content exists, but studies generally indicate a low and temporary impact rather than a sustained decrease.

Likelihood Possible Evidence A
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, beet might decrease the levels and clinical effects of CYP1A2 substrates.
In vitro research suggests that beet induces CYP1A2 enzymes.

Likelihood Possible Evidence D
organic Beet Juice full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Beet Juice 500 mg, from the product label.

Swanson

See all Swanson products
Name
Swanson Health Products
City
Fargo
State
ND
ZipCode
58104
Phone Number
1-800-437-4148
Web Address
swanson.com
Pharmacist Counseling Corner

Beet Juice 500 mg by Swanson: Common Questions

Does Beet Juice 500 mg by Swanson interact with any medications?
Yes. Based on its ingredients, Beet Juice 500 mg has a known interaction with 861 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Beet Juice 500 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will this turn my urine and stools red?
Yes, red or dark stools and red urine are the most common side effects. This is just the beet pigment passing through your body and is not harmful. Some people also report black stools.
Does beet juice actually improve athletic performance?
Beet juice is rated possibly effective for athletic performance and for reducing exercise-induced muscle soreness — the soreness you feel a day or two after a hard workout. The evidence is suggestive but not definitive.
Is this safe to take long-term?
Beet as a food is safe long-term for most people, but concentrated beet supplements like this one lack long-term safety data, so use caution if you plan to take it regularly. Very large amounts have rarely been linked to low blood calcium and kidney damage.
Can I take this if I'm pregnant or breastfeeding?
Safety data for concentrated beet supplements during pregnancy and breastfeeding are not on file. Talk with your doctor or pharmacist for personalized advice if you're pregnant or nursing.
What is betanin?
Betanin is the main pigment in beet — it's what makes beets deep red. It's the compound responsible for beet's interaction with certain liver enzymes that process medications.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Beet Juice 500 mg is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Beet Juice 500 mg label
Go deeper

The Full Monographs Behind Beet Juice 500 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Beet

Interacts with 861 drugs

Beet, especially beetroot juice, is a nitrate-rich food that may modestly lower blood pressure and slightly improve exercise performance in some people. It is generally safe as a food, but s...

Read the full Beet monograph →
Sources

Sources & How We Checked

Beet Juice 500 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 14 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Beet 14 references
  1. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
  2. Clifford T, Berntzen B, Davison GW, et al. Effects of beetroot juice on recovery of muscle function and performance between bouts of repeated sprint exercise. Nutrients 2016;8. pii: E506. PubMed
  3. Siervo M, Lara J, Ogbonmwan I, Mathers JC. Inorganic nitrate and beetroot juice supplementation reduces blood pressure in adults: a systematic review and meta-analysis. J Nutr 2013;143:818-26. PubMed
  4. Clifford T, Howatson G, West DJ, Stevenson EJ. Beetroot juice is more beneficial than sodium nitrate for attenuating muscle pain after strenuous eccentric-bias exercise. Appl Physiol Nutr Metab. 2017;42(11):1185-1191. PubMed
  5. Clifford T, Bell O, West DJ, Howatson G, Stevenson EJ. The effects of beetroot juice supplementation on indices of muscle damage following eccentric exercise. Eur J Appl Physiol. 2016;116(2):353-62. PubMed
  6. Wylie LJ, Kelly J, Bailey SJ, et al. Beetroot juice and exercise: pharmacodynamic and dose-response relationships. J Appl Physiol (1985). 2013;115(3):325-36. PubMed
  7. Garnacho-Castaño MV, Palau-Salvà G, Cuenca E, et al. Effects of a single dose of beetroot juice on cycling time trial performance at ventilatory thresholds intensity in male triathletes. J Int Soc Sports Nutr. 2018;15(1):49. PubMed
  8. Rasica L, Porcelli S, Marzorati M, et al. Ergogenic effects of beetroot juice supplementation during severe-intensity exercise in obese adolescents. Am J Physiol Regul Integr Comp Physiol. 2018;315(3):R453-R460. PubMed
  9. Henrohn D, Björkstrand K, Lundberg JO, et al. Effects of oral supplementation with nitrate-rich beetroot juice in patients with pulmonary arterial hypertension-results from BEET-PAH, an exploratory randomized, double-blind, placebo-controlled, crosso
  10. Serra-Payá N, Garnacho-Castaño MV, Sánchez-Nuño S, et al. The relationship between resistance exercise performance and ventilatory efficiency after beetroot juice intake in well-trained athletes. Nutrients 2021;13(4):1094. PubMed
  11. Haron MH, Dale O, Martin K, et al. Evaluation of the Herb-Drug Interaction Potential of Commonly Used Botanicals on the US Market with Regard to PXR- and AhR-Mediated Influences on CYP3A4 and CYP1A2. J Diet Suppl 2022. PubMed
  12. Hemmatinafar M, Zaremoayedi L, Koushkie Jahromi M, et al. Effect of Beetroot Juice Supplementation on Muscle Soreness and Performance Recovery after Exercise-Induced Muscle Damage in Female Volleyball Players. Nutrients 2023;15(17):3763. PubMed
  13. Lim SH, Bae S, Lee HS, Han HK, Choi CI. Effect of Betanin, the Major Pigment of Red Beetroot (Beta vulgaris L.), on the Activity of Recombinant Human Cytochrome P450 Enzymes. Pharmaceuticals (Basel) 2023;16(9):1224. PubMed
  14. Oscherwitz M, Tamayo RM, Heudebert A, Centor R. A Case of Pseudo-Hematochezia from Beet Supplement Ingestion. Am J Med 2023;136(9):e177-e178. PubMed

See these in context on the Beet monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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