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Dietary supplement

Bergamot BPF Ingredients & Drug Interactions

by Ortho Molecular Products

Bergamot BPF label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Bergamot BPF against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Bergamot BPF is a dietary supplement by Ortho Molecular Products with 1 active ingredient. Its ingredients are commonly taken for high cholesterol, heart and metabolic health, anxiety and stress (aromatherapy).Based on those ingredients, 410 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Bergamot Orange extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Bergamot BPF by Ortho Molecular Products

Ask about any prescription or over-the-counter medication and we check it for interactions with Bergamot BPF by Ortho Molecular Products — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Bergamot BPF by Ortho Molecular Products

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

Bergamot BPF contains one active ingredient: bergamot orange extract. Bergamot is a citrus fruit, and its extract has been studied for its effects on cholesterol and liver health.

The capsule itself is made from vegetable material, and the inactive ingredients include microcrystalline cellulose, magnesium stearate, stearic acid, and silicon dioxide — these are just fillers and binders that hold the capsule together.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: Heart and metabolic health support.
  • We looked for evidence on: Hyperlipidemia, Metabolic syndrome, Nonalcoholic fatty liver disease (NAFLD), Impaired glucose tolerance (prediabetes), Obesity, Cardiovascular health — and 3 related terms.
  • The strongest evidence on file: Bergamot is rated "Possibly Effective" for Hyperlipidemia (Natural Medicines).
  • Also on file: Bergamot is rated "Insufficient Reliable Evidence To Rate" for Nonalcoholic fatty liver disease (NAFLD), Obesity, Impaired glucose tolerance (prediabetes), Metabolic syndrome.

The evidence for bergamot extract centers on cholesterol and fat in the blood. The data suggests it's possibly effective for high cholesterol (hyperlipidemia), though we'd want to see more robust studies to be certain.

For mental alertness, the evidence points to it being possibly ineffective. As for nonalcoholic fatty liver disease and autism spectrum disorder, we don't have enough reliable evidence to rate whether it works for those purposes.

The evidence, ingredient by ingredient Bergamot

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

The oral extract form in this capsule appears to be well tolerated in the short term, and only one case of heartburn was reported in clinical trials. The safety picture changes if you're using the essential oil (which can be toxic if swallowed) or applying it topically — topical use carries a risk of skin reactions including blisters, redness, and photosensitivity, especially in fair-skinned people.

Because there isn't enough safety data, the facts advise against bergamot supplements during pregnancy and while breastfeeding.

Side effects, ingredient by ingredient Bergamot

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Bergamot.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 410 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take this, double-check any photosensitizing drugs you're on — bergamot can increase your skin's reaction to sun exposure (Moderate severity). Also check any antidiabetes medications — bergamot may lower blood sugar, which could raise the risk of blood sugar going too low (Moderate severity).

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Bergamot extract is worth considering if you're looking at natural support for cholesterol, but it's critical you check it against any photosensitizing medications or blood sugar medications you take. Talk to your pharmacist or doctor before starting, especially if you're pregnant, nursing, or spend a lot of time in the sun.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Apr 25, 2018.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Bergamot BPF, straight from the product label.

Brand Ortho Molecular Products
Barcode (UPC) 615033005986
Net contents 60 Capsule(s)
Market status On market
Date entered into DSLD Apr 25, 2018
DSLD ID 174733
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Bergamot BPF by Ortho Molecular Products, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
30
UPC/BARCODE
615033005986
IngredientAmount% DV
Bergamot Orange extract1 Gram(s)--

Other ingredients: natural Vegetable Capsules, Microcrystalline Cellulose, Magnesium Stearate, Stearic Acid, Silicon Dioxide

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested Use: 2 capsules per day or as recommended by your health care professional.

Formulation

Formulated To Be Free Of Allergens Derived From: Gluten, corn, yeast, artificial colors and flavors.

Precautions

If you are pregnant or nursing, consult your physician before taking this product.

As with all dietary supplements, some individuals may not tolerate or may be allergic to the ingredients used. Please read the ingredient panel carefully prior to ingestion. Cease taking this product and consult your physician if you have negative reactions upon ingestion.

Keep out of reach of children.

This product was sealed for your protection. Do not use if outer logoed neck seal or inner-seal is missing or damaged.

Do not accept if label shows signs of tampering

Storage

Keep container tightly closed. Store at room temperature.

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

General

Product #598060 Label ID L-OMP100-598060-B V2

Seals/Symbols

Vcaps

General Statements

Learn more

Cardiovascular health

Professional Strength: Not for sale through Amazon.com

Brand IP Statement(s)

VitaSecure

Because efficacy matters

Bergamonte and Bergamot Polyphenolic Fraction are the registered trademark of HP Ingredients.

FDA Statement of Identity

Dietary Supplement

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Bergamot BPF by Ortho Molecular Products label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Bergamot BPF label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Bergamot BPF by Ortho Molecular Products

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size2 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Bergamot Orange extract

Interacts with
410 drugs
1 Gram(s) per serving Form: Bergamot Polyphenolic Fraction comprised of

Bergamot is a Mediterranean citrus fruit, and its standardized extract is most often used to support cholesterol and heart health, with some early but...

Bergamot Orange extract monograph & interactions

Other (inactive) ingredients: Natural Vegetable Capsules, Microcrystalline Cellulose, Magnesium Stearate, Stearic Acid, Silicon Dioxide. These complete the product’s ingredient list but are not active constituents.

Interaction report

Bergamot BPF by Ortho Molecular Products Drug Interactions

Want to check YOUR meds against Bergamot BPF?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
410Drugs
410 Moderate

Ingredients driving the most interactions

Bergamot Orange extract 410

Individual Drug Interactions

The ingredients in Bergamot BPF interact with 410 drugs. Click any drug to see the details.

1 of the 1 ingredient in Bergamot BPF interact with drugs. Each result below shows which ingredient is responsible. Bergamot Orange extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Bergamot BPF with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Bergamot Orange extract2 drug types · 410 drugs

Antidiabetes Drugs

Theoretically, taking bergamot with antidiabetes drugs might increase the risk of hypoglycemia.
Animal research suggests that bergamot juice has hypoglycemic effects.

Likelihood Possible Evidence D
Photosensitizing Drugs

Theoretically, topical bergamot essential oil might increase the risk of side effects when used along with photosensitizing drugs.
Bergamot contains bergapten, which has photosensitizing effects.

Likelihood Probable Evidence D
Bergamot Orange extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Bergamot BPF, from the product label.

Ortho Molecular Products

See all Ortho Molecular Products products
Name
Ortho Molecular Products, Inc.
Street Address
1991 Duncan Place
City
Woodstock
State
IL
ZipCode
60098
Web Address
OrthoMolecularProducts.com
Pharmacist Counseling Corner

Bergamot BPF by Ortho Molecular Products: Common Questions

Does Bergamot BPF by Ortho Molecular Products interact with any medications?
Yes. Based on its ingredients, Bergamot BPF has a known interaction with 410 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Bergamot BPF contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take Bergamot BPF if I'm pregnant?
The safety data advises against it during pregnancy — there isn't enough information to know it's safe. Talk with your doctor or pharmacist before taking it.
Is bergamot safe to use if I'm breastfeeding?
Safety while breastfeeding is unknown, so the safer choice is to avoid it. Ask your pharmacist or doctor if you have questions about your specific situation.
What's bergamot actually used for?
The evidence suggests bergamot extract is possibly effective for high cholesterol. It's been studied for fatty liver disease and autism as well, but we don't have enough reliable evidence to say whether it works for those.
Will this give me side effects?
When taken orally as an extract in capsule form like this one, bergamot is generally well tolerated. Only one case of heartburn was reported in clinical research. Keep in mind that topical use or essential oil is a different story — those carry a risk of skin reactions.
What's bergapten, and why does it matter?
Bergapten is a compound naturally present in bergamot that makes your skin more sensitive to sun damage. That's why there's a concern if you're also taking medications that make you photosensitive — the combination could increase your risk of a sun-related skin reaction.
Can bergamot lower my blood sugar too much?
Animal research suggests bergamot has effects that lower blood sugar, so if you're on antidiabetes medication, taking them together could theoretically increase your risk of blood sugar going too low. That's why it's important to check with your pharmacist before starting.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Bergamot BPF label
Go deeper

The Full Monographs Behind Bergamot BPF’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Bergamot

Interacts with 410 drugs

Bergamot is a Mediterranean citrus fruit, and its standardized extract is most often used to support cholesterol and heart health, with some early but promising research. The essential oil i...

Read the full Bergamot monograph →
Sources

Sources & How We Checked

Bergamot BPF's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 17 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Bergamot 17 references
  1. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
  2. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
  3. Naganuma M, Hirose S, Nakayama Y, et al. A study of the phototoxicity of lemon oil. Arch Dermatol Res 1985;278:31-6. . PubMed
  4. Kaddu, S., Kerl, H., and Wolf, P. Accidental bullous phototoxic reactions to bergamot aromatherapy oil. J.Am.Acad.Dermatol. 2001;45(3):458-461. PubMed
  5. Finsterer, J. Earl Grey tea intoxication. Lancet 4-27-2002;359(9316):1484. PubMed
  6. Gruson, L. M. and Chang, M. W. Berloque dermatitis mimicking child abuse. Arch.Pediatr.Adolesc.Med. 2002;156(11):1091-1093. PubMed
  7. Weisenseel, P. and Woitalla, S. [Toxic mustard plaster dematitis and phototoxic dematitis after application of bergamot oil]. MMW.Fortschr.Med. 12-15-2005;147(51-52):53, 55.
  8. Placzek, M., Fromel, W., Eberlein, B., Gilbertz, K. P., and Przybilla, B. Evaluation of phototoxic properties of fragrances. Acta Derm.Venereol. 2007;87(4):312-316. PubMed
  9. Mollace, V., Sacco, I., Janda, E., Malara, C., Ventrice, D., Colica, C., Visalli, V., Muscoli, S., Ragusa, S., Muscoli, C., Rotiroti, D., and Romeo, F. Hypolipemic and hypoglycaemic activity of bergamot polyphenols: from animal models to human studies. F PubMed
  10. Morliere, P., Huppe, G., Averbeck, D., Young, A. R., Santus, R., and Dubertret, L. In vitro photostability and photosensitizing properties of bergamot oil. Effects of a cinnamate sunscreen. J.Photochem.Photobiol.B 1990;7(2-4):199-208. PubMed
  11. Young, A. R., Walker, S. L., Kinley, J. S., Plastow, S. R., Averbeck, D., Morliere, P., and Dubertret, L. Phototumorigenesis studies of 5-methoxypsoralen in bergamot oil: evaluation and modification of risk of human use in an albino mouse skin model. J.P PubMed
  12. Girard, J., Unkovic, J., Delahayes, J., and Lafille, C. [Phototoxicity of Bergamot oil. Comparison between humans and guinea pigs]. Dermatologica 1979;158(4):229-243.
  13. Zaynoun, S. T., Johnson, B. E., and Frain-Bell, W. A study of oil of bergamot and its importance as a phototoxic agent. II. Factors which affect the phototoxic reaction induced by bergamot oil and psoralen derivatives. Contact Dermatitis 1977;3(5):225-23 PubMed
  14. Zacher, K. D. and Ippen, H. [Contact dermatitis caused by bergamot oil]. Derm.Beruf.Umwelt. 1984;32(3):95-97.
  15. Yasui, Y. and Hirone, T. Action spectrum for bergamot-oil phototoxicity measured by sunburn cell counting. J.Dermatol. 1994;21(5):319-322. PubMed
  16. Zaynoun, S. T., Johnson, B. E., and Frain-Bell, W. A study of oil of bergamot and its importance as a phototoxic agent. I. Characterization and quantification of the photoactive component. Br.J.Dermatol. 1977;96(5):475-482. PubMed
  17. Bruno A, Pandolfo G, Crucitti M, Cedro C, Zoccali RA, Muscatello MRA. Bergamot Polyphenolic Fraction Supplementation Improves Cognitive Functioning in Schizophrenia: Data From an 8-Week, Open-Label Pilot Study. J Clin Psychopharmacol 2017;37(4):468-71. PubMed

See these in context on the Bergamot monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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