Interactions on record — worth a quick check against your medications. Check your meds →
Dietary supplement

Lutein with FloraGLO 20 mg Ingredients & Drug Interactions

by Doctor's Best

Lutein with FloraGLO 20 mg label
See full label image
Softgel Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 30, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Lutein with FloraGLO 20 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Lutein with FloraGLO 20 mg is a dietary supplement by Doctor's Best with 2 active ingredients. Its ingredients are commonly taken for eye health, age-related macular degeneration, cataract prevention.Based on those ingredients, 86 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are FloraGLO. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Lutein with FloraGLO 20 mg by Doctor's Best

Ask about any prescription or over-the-counter medication and we check it for interactions with Lutein with FloraGLO 20 mg by Doctor's Best — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
Prefer a human? Send your question to our licensed pharmacists — free, answered by email within 24 hours.

HelloPharmacist Scorecard of Lutein with FloraGLO 20 mg by Doctor's Best

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 20, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

This softgel contains 2 active ingredients: lutein (from FloraGLO, a trademark ingredient source) and zeaxanthin, both naturally occurring carotenoids that concentrate in the eye. The remaining content is safflower oil, yellow beeswax, sunflower lecithin, gelatin, glycerin, and purified water — inactive ingredients that help deliver and form the softgel.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: support visual function and eye health.
  • We looked for evidence on: Age-related macular degeneration (AMD), Asthenopia (eye strain), Cataracts, Central serous retinopathy, Choroideremia, Diabetic retinopathy — and 4 related terms.
  • The strongest evidence on file: Lutein is rated "Possibly Effective" for Age-related macular degeneration (AMD) (Natural Medicines).
  • Also on file: Lutein is rated "Possibly Effective" for Cataracts.
  • Also on file: Zeaxanthin is rated "Possibly Effective" for Age-related macular degeneration (AMD).

The evidence for lutein is strongest for age-related macular degeneration (AMD) and cataracts, where it's rated possibly effective. For other eye conditions — retinitis pigmentosa, retinopathy of prematurity, and necrotizing enterocolitis — the evidence suggests it doesn't work.

Zeaxanthin is also rated possibly effective for AMD but has insufficient evidence for cognitive decline, Alzheimer disease, asthma, breast cancer, and bronchopulmonary dysplasia.

The evidence, ingredient by ingredient Lutein Zeaxanthin

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Lutein at doses up to 20 mg daily is generally well tolerated with no reported adverse effects in trials. Both ingredients are rated likely safe in pregnancy and lactation, though the safety data on concentrated supplement doses — rather than food sources — in pregnancy and while breastfeeding isn't as well established, so it's worth discussing with your doctor or pharmacist before starting.

Lutein naturally appears in breast milk, but higher supplement doses haven't been well studied.

Side effects, ingredient by ingredient Lutein Zeaxanthin

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 2 matched ingredients can interact with medications — Zeaxanthin.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 86 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check your antidiabetes medications — especially if you're already managing tight blood sugar control. Zeaxanthin's moderate interaction with these drugs could increase the risk of low blood sugar.

A quick call to your pharmacist can confirm whether your specific medications need adjustment or monitoring.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This product is worth considering if you're concerned about age-related macular degeneration or cataracts and want to add a lutein and zeaxanthin supplement. If you take diabetes medications, check with your doctor or pharmacist first — zeaxanthin may theoretically lower blood sugar further.

A quick conversation with your pharmacist about your specific medications takes the guesswork out.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Feb 22, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Lutein with FloraGLO 20 mg, straight from the product label.

Brand Doctor's Best
Barcode (UPC) 753950001923
Net contents 60 Softgel(s)
Market status On market
Date entered into DSLD Feb 22, 2024
DSLD ID 302687
Product type Non-nutrient/non-botanical
Supplement form Softgel Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Lutein with FloraGLO 20 mg by Doctor's Best, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Softgel(s)
Maximum serving Sizes:
1 Softgel(s)
Servings per container
60
UPC/BARCODE
753950001923
IngredientAmount% DV
FloraGLO20 mg--
FloraGLO1 mg--

Other ingredients: Safflower Oil, Yellow Beeswax, Sunflower Lecithin, Gelatin, Glycerin, Water, Purified

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Doctor's Best Lutein with FloraGLO supplies highly bioavailable carotenoids nutrients lutein and zeaxanthin from Marigold flowers.

With FloraGLO lutein

Formulation

FloraGLO is manufactured with a proprietary process to ensure that the naturally-sourced lutein maintains its quality and consistency. It's the first lutein brand introduced into the global marketplace and the most clinically researched lutein in the world. Lutein and zeaxanthin are the major carotenoids found in the blood, and are highly concentrated in the retina of the eye.

Helps support visual function Helps absorb damaging blue light Helps support cognitive acuity Helps neutralize free radicals

Helps support visual function and neutralize free radicals

Non-GMO Gluten free Soy free

General Statements

Constant exposure to ultra violet (UV) and blue light emitted from computers and mobile devices may potentially damage to the retinal cell.

Facebook instagram twitter

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Brand IP Statement(s)

Doctor's Best Science-Based Nutrition

FloraGLO is a registered trademark of Kemin Industries, Inc.

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Suggested Adult Use: Take 1 softgel daily with or without food, or as recommended by a nutritionally informed physician.

Storage

Store in a cool dry place.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Lutein with FloraGLO 20 mg by Doctor's Best label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Lutein with FloraGLO 20 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Lutein with FloraGLO 20 mg by Doctor's Best

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Softgel(s) Dosage formSoftgel Capsule Servings per container60 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

FloraGLO

No known
interactions
20 mg per serving Form: Lutein

Lutein is a plant-based antioxidant pigment that concentrates in the eye, and the best evidence suggests it (often combined with zeaxanthin) may help...

FloraGLO monograph & interactions

FloraGLO

Interacts with
86 drugs
1 mg per serving Form: Zeaxanthin

Zeaxanthin is a carotenoid pigment that, along with lutein, concentrates in the macula of the eye and may help support long-term eye health. The stron...

FloraGLO monograph & interactions

Other (inactive) ingredients: Safflower Oil, Yellow Beeswax, Sunflower Lecithin, Gelatin, Glycerin, Water, Purified. These complete the product’s ingredient list but are not active constituents.

Interaction report

Lutein with FloraGLO 20 mg by Doctor's Best Drug Interactions

Want to check YOUR meds against Lutein with FloraGLO 20 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
86Drugs
86 Moderate

Ingredients driving the most interactions

FloraGLO 86

Individual Drug Interactions

The ingredients in Lutein with FloraGLO 20 mg interact with 86 drugs. Click any drug to see the details.

1 of the 2 ingredients in Lutein with FloraGLO 20 mg interact with drugs. Each result below shows which ingredient is responsible. FloraGLO

Each ingredient & the kinds of drugs it affects

For each ingredient in Lutein with FloraGLO 20 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

FloraGLO1 drug type · 86 drugs

Antidiabetes Drugs

Theoretically, taking zeaxanthin with antidiabetes drugs might increase the risk of hypoglycemia.
In an animal diabetic model, zeaxanthin has hypoglycemic effects. However, population research has found that increasing intake of dietary zeaxanthin plus lutein does not decrease the risk of developing type 2 diabetes.

Likelihood Possible Evidence D
FloraGLO full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Lutein with FloraGLO 20 mg, from the product label.

Doctor's Best

See all Doctor's Best products
Name
Doctor's Best, Inc.
City
Tustin
State
California
ZipCode
92780
Phone Number
(800) 777-2474
Web Address
www.drbvitamins.com
Pharmacist Counseling Corner

Lutein with FloraGLO 20 mg by Doctor's Best: Common Questions

Does Lutein with FloraGLO 20 mg by Doctor's Best interact with any medications?
Yes. Based on its ingredients, Lutein with FloraGLO 20 mg has a known interaction with 86 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Lutein with FloraGLO 20 mg contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will this help my age-related macular degeneration (AMD)?
Both lutein and zeaxanthin are rated possibly effective for AMD, which means the evidence shows promise but isn't definitive. They're the carotenoids your eye naturally uses, so supplementing does have a rational basis — but talk to your eye doctor about whether it fits into your overall plan for AMD.
Is it safe to take if I'm pregnant or breastfeeding?
Both ingredients are rated likely safe in pregnancy and lactation. That said, most of the safety data we have is on lutein and zeaxanthin from foods, not concentrated supplements at higher doses, so there isn't enough information to be completely certain. Check with your doctor or pharmacist before taking it during pregnancy or while nursing.
What dose am I getting, and is it safe?
You're getting 20 mg total lutein. Studies have shown that lutein at 20 mg daily hasn't caused adverse effects in trial participants, and it's generally well tolerated at typical supplement doses.
Can I take this with my diabetes medication?
Zeaxanthin, one of the ingredients, may theoretically increase the risk of low blood sugar if you're on antidiabetes drugs — that's a moderate interaction. Talk to your doctor or pharmacist about your specific diabetes medication before starting, because they can advise whether monitoring or a dose adjustment makes sense.
Does this have any fillers or extra ingredients I should know about?
Besides the two active carotenoids, the softgel contains safflower oil, yellow beeswax, sunflower lecithin, gelatin, glycerin, and purified water — all inactive ingredients that make up the softgel. No unnecessary additives.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Lutein with FloraGLO 20 mg is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Lutein with FloraGLO 20 mg label
Go deeper

The Full Monographs Behind Lutein with FloraGLO 20 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Lutein

Lutein is a plant-based antioxidant pigment that concentrates in the eye, and the best evidence suggests it (often combined with zeaxanthin) may help slow progression of age-related macular...

Read the full Lutein monograph → Herb & supplement monograph

Zeaxanthin

Interacts with 86 drugs

Zeaxanthin is a carotenoid pigment that, along with lutein, concentrates in the macula of the eye and may help support long-term eye health. The strongest evidence relates to slowing progres...

Read the full Zeaxanthin monograph →
Sources

Sources & How We Checked

Lutein with FloraGLO 20 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 6 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Lutein 2 references
  1. Brown L, Rimm EB, Seddon JM, et al. A prospective study of carotenoid intake and risk of cataract extraction in US men. Am J Clin Nutr 1999;70:517-24. PubMed
  2. Chasan-Taber L, Willett WC, Seddon JM, et al. A prospective study of carotenoid and vitamin A intakes and risk of cataract extraction in US women. Am J Clin Nutr 1999;70:509-16. PubMed

See these in context on the Lutein monograph →

Zeaxanthin 4 references
  1. Montonen J, Knekt P, Jarvinen R, Reunanen A. Dietary antioxidant intake and risk of type 2 diabetes. Diabetes Care 2004;27:362-6. PubMed
  2. Leermakers ET, Darweesh SK, Baena CP, et al. The effects of lutein on cardiometabolic health across the life course: a systematic review and meta-analysis. Am J Clin Nutr 2016;103(2):481-94. PubMed
  3. Kou L, Du M, Zhang C, Dai Z, Li X, Zhang B. The Hypoglycemic, Hypolipidemic, and Anti-Diabetic Nephritic Activities of Zeaxanthin in Diet-Streptozotocin-Induced Diabetic Sprague Dawley Rats. Appl Biochem Biotechnol 2017;182(3):944-955. PubMed
  4. Xu X, Zhao X, Berde Y, Low YL, Kuchan MJ. Milk and Plasma Lutein and Zeaxanthin Concentrations in Chinese Breast-Feeding Mother-Infant Dyads With Healthy Maternal Fruit and Vegetable Intake. J Am Coll Nutr 2019;38(2):179-184. PubMed

See these in context on the Zeaxanthin monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring
Supplement interaction checker › Check any supplement or product against your medications Drug–drug interactions › Check two or more of your medications against each other Browse medications A–Z › Every drug we've checked against herbs & supplements NDC & pricing lookup › Find a drug’s NDCs, packaging and costs Ask a pharmacist › Free, personal answer from our licensed team