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Dietary supplement

Betula Pendula Ingredients & Drug Interactions

by UNDA Gemmo

Betula Pendula label
See full label image
Liquid Category: Botanical
Most serious interaction: Minor
Clinical methodology reviewed by · Updated Sep 23, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Betula Pendula against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Minor

Betula Pendula is a dietary supplement by UNDA Gemmo with 1 active ingredient. Its ingredients are commonly taken for urinary tract and 'flushing' support, joint pain and arthritis, mild fluid retention (diuretic).Based on those ingredients, 75 medications have a known interaction with it, the most serious rated minor. The ingredients most likely to interact are Birch (Betula pendula) seed extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Betula Pendula by UNDA Gemmo

Ask about any prescription or over-the-counter medication and we check it for interactions with Betula Pendula by UNDA Gemmo — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Betula Pendula by UNDA Gemmo

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 16, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: birch (Betula pendula) seed extract, a plant-based substance traditionally used for joint and skin concerns. The liquid also includes glycerin, ethanol, and purified water as inactive ingredients to preserve and deliver the extract.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Birch product and its label doesn't state a use — see Birch's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence we hold does not establish that birch seed extract works for joint pain, hair loss (alopecia), or dandruff. All three uses show insufficient reliable evidence to rate, so we can't say whether this product will deliver the results you're hoping for.

The evidence, ingredient by ingredient Birch

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Birch is generally well tolerated in food-like amounts, but you should know that birch and birch pollen can trigger allergic reactions in some people — ranging from mild to contact dermatitis on the skin. The safety data advises against birch supplements during pregnancy and while breastfeeding, so if either applies to you, talk with your doctor or pharmacist about whether this product is right for you.

Side effects, ingredient by ingredient Birch

Meds to double-check

Minor interactions only
Known Interaction Concern · database check
Minor only

Only Minor-severity interactions are documented for these ingredients.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Birch.
  • The most serious interaction on file is rated Minor.
  • For scale: 75 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take diuretic drugs (water pills) for high blood pressure, heart failure, or edema, check your exact medication with your pharmacist before starting this product — birch might theoretically interfere with how they work.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Only minor medication interactions are documented, and safety information is well characterized.

This single-ingredient product may appeal to you if you're exploring traditional herbal options for joint or scalp concerns, but the evidence for those uses isn't established in our data. The main thing to check is whether you take a diuretic — if you do, clear it with your pharmacist before starting.

Also watch for any sign of an allergic reaction, especially if you have birch pollen sensitivity.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Dec 26, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Betula Pendula, straight from the product label.

Brand UNDA Gemmo
Barcode (UPC) 88319630840
Net contents 4.2 Fluid Ounce(s); 125 mL
Market status On market
Date entered into DSLD Dec 26, 2020
DSLD ID 241185
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other
Intended target group(s) Children 4 or More Years of Age, Adult (18 - 50 Years), Women (not pregnant or lactating)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Betula Pendula by UNDA Gemmo, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1.25 mL
Maximum serving Sizes:
1.25 mL
Servings per container
100
UPC/BARCODE
88319630840
IngredientAmount% DV
Birch (Betula pendula) seed extract1.25 mL--

Other ingredients: Glycerin, Ethanol, purified Water

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Recommended Dose: Adults and children (over 12 years): Take 50 drops (1.25 ml) three times daily in a small amount of water or as recommended by your healthcare practitioner.

Precautions

Risk Information: If you are pregnant or breastfeeding, do not use, unless directed by your healthcare practitioner.

Hypersensitivity has been known to occur; in which case discontinue use.

Formula

Semen seed

FDA Statement of Identity

Dietary Supplement

General Statements

Seroyal UNDA

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Betula Pendula by UNDA Gemmo label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Betula Pendula label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Betula Pendula by UNDA Gemmo

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1.25 mL Dosage formLiquid Servings per container100 Amounts shown are per serving.

Birch (Betula pendula) seed extract

Interacts with
75 drugs
1.25 mL per serving

Birch is a tree whose leaves, bark, and sap are used in traditional remedies, most often as a mild diuretic or for joint and urinary complaints. Solid...

Birch (Betula pendula) seed extract monograph & interactions

Other (inactive) ingredients: Glycerin, Ethanol, Purified Water. These complete the product’s ingredient list but are not active constituents.

Interaction report

Betula Pendula by UNDA Gemmo Drug Interactions

Want to check YOUR meds against Betula Pendula?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
75Drugs
75 Minor

Ingredients driving the most interactions

Birch (Betula pendula) seed extract 75

Individual Drug Interactions

The ingredients in Betula Pendula interact with 75 drugs. Click any drug to see the details.

1 of the 1 ingredient in Betula Pendula interact with drugs. Each result below shows which ingredient is responsible. Birch (Betula pendula) seed extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Betula Pendula with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Birch (Betula pendula) seed extract1 drug type · 75 drugs

Diuretic Drugs

Theoretically, birch might interfere with diuretic therapy.

Likelihood Possible Evidence D
Birch (Betula pendula) seed extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Betula Pendula, from the product label.

UNDA Gemmo

See all UNDA Gemmo products
Name
Seroyal USA
City
Pittsburg
State
PA
ZipCode
15275
Phone Number
1-888-737-6925
Pharmacist Counseling Corner

Betula Pendula by UNDA Gemmo: Common Questions

Does Betula Pendula by UNDA Gemmo interact with any medications?
Yes. Based on its ingredients, Betula Pendula has a known interaction with 75 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Betula Pendula contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm pregnant or breastfeeding?
The safety data advises against birch supplements during pregnancy and while breastfeeding. Talk with your doctor or pharmacist about whether this product is right for you in either situation.
Will this help my joint pain?
The evidence we hold doesn't establish that birch seed extract works for joint pain — it shows insufficient reliable evidence to rate. That doesn't mean it won't help you, just that we can't say based on the data available.
Could I have an allergic reaction to this?
Yes. Birch and birch pollen can cause allergic reactions, including contact dermatitis (a skin rash). If you have birch pollen allergies, be especially cautious and watch for any rash, itching, or other signs of sensitivity.
What's in this product besides the active ingredient?
The liquid contains glycerin, ethanol, and purified water as inactive ingredients. These help preserve and deliver the birch extract.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Betula Pendula is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Betula Pendula label
Go deeper

The Full Monographs Behind Betula Pendula’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Birch

Interacts with 75 drugs

Birch is a tree whose leaves, bark, and sap are used in traditional remedies, most often as a mild diuretic or for joint and urinary complaints. Solid human evidence is limited, and birch is...

Read the full Birch monograph →
Sources

Sources & How We Checked

Betula Pendula's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 4 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Birch 4 references
  1. Robbers JE, Tyler VE. Tyler's Herbs of Choice: The Therapeutic Use of Phytomedicinals. New York, NY: The Haworth Herbal Press, 1999.
  2. Lahti, A. and Hannuksela, M. Immediate contact allergy to birch leaves and sap. Contact Dermatitis 1980;6(7):464-465. PubMed
  3. Allam JP, Wuestenberg E, Wolf H, et al. Immunologic response and safety in birch pollen sublingual versus oral vestibule immunotherapy: a pilot study. J Allergy Clin Immunol. 2014;133(6):1757-9.e3. PubMed
  4. Meyer-Hoffert U, Brasch J. Allergic contact dermatitis caused by betulin-containing triterpene extract from the outer bark of birch (Betula alba). Contact Dermatitis. 2013;68(6):382-3.

See these in context on the Birch monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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