Interactions on record — worth a quick check against your medications. Based on 2 of 3 ingredients. Check your meds →
Dietary supplement

BioAcidophilus Ingredients & Drug Interactions

by BioCare

BioAcidophilus label
See full label image
Capsule Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking BioAcidophilus against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

BioAcidophilus is a dietary supplement by BioCare with 3 active ingredients. Its ingredients are commonly taken for digestive and gut health, prebiotic to support good bacteria, constipation relief.Based on those ingredients, 182 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Lactobacillus acidophilus. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against BioAcidophilus by BioCare

Ask about any prescription or over-the-counter medication and we check it for interactions with BioAcidophilus by BioCare — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of BioAcidophilus by BioCare

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 3 of its 3 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

BioAcidophilus contains three active ingredients: Fructooligosaccharides (FOS), Bifidobacterium, and Lactobacillus acidophilus. FOS is a prebiotic — a type of fiber that feeds beneficial bacteria in your gut.

Bifidobacterium and Lactobacillus acidophilus are both probiotics, live microorganisms intended to support your gut health and digestion. The capsule also contains inactive ingredients like cellulose, silicon dioxide, and magnesium stearate.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: Live bacteria for digestive and gut health.
  • We looked for evidence on: Antibiotic-associated diarrhea, Bacterial vaginosis, Clostridioides difficile infection, Colic, Constipation, Inflammatory bowel disease (IBD) — and 4 related terms.
  • The strongest evidence on file: Lactobacillus Acidophilus is rated "Possibly Effective" for Antibiotic-associated diarrhea (Natural Medicines).
  • Also on file: Lactobacillus Acidophilus is rated "Possibly Effective" for Bacterial vaginosis, Irritable bowel syndrome (IBS).
  • Also on file: Fructo-oligosaccharides (fos) is rated "Insufficient Reliable Evidence To Rate" for Constipation.

The evidence for what this product can do varies. Lactobacillus acidophilus is possibly effective for irritable bowel syndrome (IBS), antibiotic-associated diarrhea, Helicobacter pylori infection, and bacterial vaginosis — meaning there's some clinical support, but the research isn't definitive yet.

For other conditions like acute respiratory infections, the evidence isn't established in the data we hold. FOS hasn't shown reliable evidence for the conditions we checked — constipation, diabetes, high cholesterol, osteoporosis, and travelers' diarrhea.

We don't have effectiveness information for Bifidobacterium on file.

The evidence, ingredient by ingredient Fructo-oligosaccharides (fos) Lactobacillus Acidophilus

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Lactobacillus acidophilus is generally well tolerated in healthy adults and children. Gastrointestinal side effects like stomach discomfort, abdominal pain, bloating, flatulence, diarrhea, and burping can occur, but they're uncommon.

In rare cases, the live bacteria have been found in bloodstream infections or abscesses, though this typically happens in people with underlying conditions that allow bacteria to move from their normal gut location. FOS is generally well tolerated in food amounts but commonly causes gas and bloating, especially at higher doses.

Trial data shows that even at doses of 2.5 to 15 grams daily for up to 8 weeks, FOS doesn't increase these symptoms compared with placebo, though some people may still experience them. We don't have pregnancy or breastfeeding safety data on file for any of these ingredients — talk with your doctor before use during pregnancy or while nursing.

Side effects, ingredient by ingredient Fructo-oligosaccharides (fos) Lactobacillus Acidophilus

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 2 matched ingredients can interact with medications — Lactobacillus Acidophilus.
  • The most serious interaction on file is rated Moderate.
  • For scale: 182 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check your antibiotic medications before you start BioAcidophilus. Lactobacillus acidophilus may reduce how well antibiotics work if you take them at the same time — separate them by a few hours to be safe.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This is a combination probiotic and prebiotic product that may help with IBS, antibiotic-related diarrhea, and a few other digestive concerns if the research holds up for you. If you're on antibiotics, space them out from this supplement to protect the live cultures.

If you're prone to gas or bloating, start low and go slow. Talk to your pharmacist before starting, especially if you have a weakened immune system or are pregnant or breastfeeding.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Aug 22, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about BioAcidophilus, straight from the product label.

Brand BioCare
Barcode (UPC) 5033290168605
Net contents 60 Vegetable Capsule(s)
Market status On market
Date entered into DSLD Aug 22, 2025
DSLD ID 336031
Product type Other Combinations
Supplement form Capsule
Dietary claims / uses All Other
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for BioAcidophilus by BioCare, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
60
UPC/BARCODE
5033290168605
IngredientAmount% DV
Fructooligosaccharides200 mg--
Bifidobacterium11.2 mg--
Lactobacillus acidophilus100 mg--

Other ingredients: Cellulose, Fructooligosaccharides, Hydroxypropyl Methylcellulose, Lactobacillus acidophilus, Silicon Dioxide, Magnesium Stearate, Bifidobacterium

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Directions: 1 capsule taken twice daily with food, or as professionally directed.

Precautions

This product should not be used as a substitute for a varied diet and healthy lifestyle. Do not exceed the stated recommended daily intake. Do not purchase if the seal is broken.

Keep out of reach of children.

If you are under medical supervision, please consult a doctor before use.

Storage

Contains a desiccant (small orange capsule) to absorb moisture, we recommend that you keep this in the jar. Keep refrigerated. Avoid direct sunlight and heat.

Formula

Lab4

20 billion LAB4 live bacteria 20 Billion live bacteria Providing a total of 20 billion live bacteria, guaranteed until the end of shelf life if stored correctly.

Seals/Symbols

Vegetarian Society Approved

FDA Statement of Identity

Food Supplement

Formulation

Vegetarian & vegan

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

BioAcidophilus by BioCare label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

BioAcidophilus label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in BioAcidophilus by BioCare

These are the 3 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Fructooligosaccharides

No known
interactions
200 mg per serving

Fructo-oligosaccharides (FOS) are a type of soluble fiber that acts as a prebiotic, meaning they feed the helpful bacteria in your gut. They are gener...

Fructooligosaccharides monograph & interactions

Bifidobacterium

11.2 mg per serving Form: Bifidobacterium animalis lactis CUL-34, Bifidobacterium bifidum CUL-20

Lactobacillus acidophilus

Interacts with
182 drugs
100 mg per serving Form: Lactobacillus acidophilus CUL-21, Lactobacillus acidophilus CUL-60

Lactobacillus acidophilus is a 'friendly' bacterium used as a probiotic to support gut and vaginal health. It is generally well tolerated in healthy p...

Lactobacillus acidophilus monograph & interactions

Other (inactive) ingredients: Cellulose, Fructooligosaccharides, Hydroxypropyl Methylcellulose, Lactobacillus acidophilus, Silicon Dioxide, Magnesium Stearate, Bifidobacterium. These complete the product’s ingredient list but are not active constituents.

Interaction report

BioAcidophilus by BioCare Drug Interactions

Want to check YOUR meds against BioAcidophilus?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
182Drugs
182 Moderate

Ingredients driving the most interactions

Lactobacillus acidophilus 182

Individual Drug Interactions

The ingredients in BioAcidophilus interact with 182 drugs. Click any drug to see the details.

1 of the 3 ingredients in BioAcidophilus interact with drugs. Each result below shows which ingredient is responsible. Lactobacillus acidophilus

Each ingredient & the kinds of drugs it affects

For each ingredient in BioAcidophilus with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Lactobacillus acidophilus1 drug type · 182 drugs

Antibiotic Drugs

Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L. acidophilus.
L. acidophilus preparations usually contain live and active organisms. Therefore, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and L. acidophilus preparations by at least two hours.

Likelihood Probable Evidence D
Lactobacillus acidophilus full monograph & interactions
The maker

Brand information

Manufacturer and brand details for BioAcidophilus, from the product label.

BioCare

See all BioCare products
Name
UK - BioCare Ltd
Street Address
1 Hedera Road
State
Redditch
ZipCode
B98 9EY
Phone Number
+44 0121 433 3727
Web Address
www.biocare.co.uk
Pharmacist Counseling Corner

BioAcidophilus by BioCare: Common Questions

Does BioAcidophilus by BioCare interact with any medications?
Yes. Based on its ingredients, BioAcidophilus has a known interaction with 182 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
BioAcidophilus contains 3 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will this help my irritable bowel syndrome?
Lactobacillus acidophilus, one of the active ingredients, is possibly effective for IBS — meaning some clinical evidence supports it, but the research isn't conclusive yet. Results vary from person to person, so talk with your doctor about whether it's worth trying for your particular situation.
Can I take this while I'm on antibiotics?
You can, but you'll want to space them out. Antibiotics can kill the live bacteria in this supplement, making it less effective. Separate them by a few hours — ask your pharmacist for the best timing based on your specific antibiotic.
Will this cause bloating and gas?
FOS, one of the ingredients, commonly causes gas and bloating at higher doses. The good news is that trial data from doses of 2.5 to 15 grams daily didn't show an increase in these symptoms compared with placebo, though some people still notice them. If you're sensitive, start with a low dose and see how you feel.
Is this safe to take if I'm pregnant or breastfeeding?
We don't have safety data on file for these ingredients during pregnancy or breastfeeding. Talk with your doctor or pharmacist before starting — they can give you personalized advice based on your situation.
What's the difference between the bacteria in this product?
Lactobacillus acidophilus and Bifidobacterium are both probiotics — live beneficial bacteria meant to support your gut. FOS is a prebiotic, which is a type of fiber that feeds the good bacteria already in your digestive system. Together, they're meant to work with your gut health.
Can this cause serious infections?
In rare cases, the live Lactobacillus acidophilus has been found in bloodstream or organ infections, but this almost always happens in people with weakened immune systems or other underlying health issues. If you have a compromised immune system, talk with your doctor before starting.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if BioAcidophilus is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

BioAcidophilus label
Go deeper

The Full Monographs Behind BioAcidophilus’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Fructo-oligosaccharides (fos)

Fructo-oligosaccharides (FOS) are a type of soluble fiber that acts as a prebiotic, meaning they feed the helpful bacteria in your gut. They are generally considered safe for most people in...

Read the full Fructo-oligosaccharides (fos) monograph → Herb & supplement monograph

Lactobacillus Acidophilus

Interacts with 182 drugs

Lactobacillus acidophilus is a 'friendly' bacterium used as a probiotic to support gut and vaginal health. It is generally well tolerated in healthy people, and there is reasonable evidence...

Read the full Lactobacillus Acidophilus monograph →
Sources

Sources & How We Checked

BioAcidophilus's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 21 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Fructo-oligosaccharides (fos) 6 references
  1. Briet F, et al. Symptomatic response to varying levels of fructo-oligosaccharides consumed occasionally or regularly. Eur J Clin Nutr 1995;49:501-7.
  2. Bouhnik Y, Vahedi K, Achour L, et al. Short-chain fructo-oligosaccharide administration dose-dependently increases fecal bifidobacteria in healthy humans. J Nutr 1999;129:113-6. PubMed
  3. Cummings JH, Macfarlane GT, Englyst HN. Prebiotic digestion and fermentation. Am J Clin Nutr 2001;73:415S-420S. PubMed
  4. Souza DDS, Tahan S, Weber TK, Araujo-Filho HB, de Morais MB. Randomized, double-blind, placebo-controlled parallel clinical trial assessing the effect of fructooligosaccharides in infants with constipation. Nutrients. 2018;10(11). pii: E1602. PubMed
  5. Andermann TM, Fouladi F, Tamburini FB, et al. A Fructo-Oligosaccharide Prebiotic Is Well Tolerated in Adults Undergoing Allogeneic Hematopoietic Stem Cell Transplantation: A Phase I Dose-Escalation Trial. Transplant Cell Ther 2021;27(11):932. PubMed
  6. Dou Y, Yu X, Luo Y, Chen B, Ma D, Zhu J. Effect of Fructooligosaccharides Supplementation on the Gut Microbiota in Human: A Systematic Review and Meta-Analysis. Nutrients 2022;14(16):3298. PubMed

See these in context on the Fructo-oligosaccharides (fos) monograph →

Lactobacillus Acidophilus 15 references
  1. Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
  2. Begtrup LM, de Muckadell OB, Kjeldsen J, Christensen RD, Jarbøl DE. Long-term treatment with probiotics in primary care patients with irritable bowel syndrome--a randomised, double-blind, placebo controlled trial. Scand J Gastroenterol 2013;48(10):1127-35 PubMed
  3. Chatterjee S, Kar P, Das T, Ray S, Gangulyt S, Rajendiran C, Mitra M. Randomised placebo-controlled double blind multicentric trial on efficacy and safety of Lactobacillus acidophilus LA-5 and Bifidobacterium BB-12 for prevention of antibiotic-associated
  4. Shavakhi A, Tabesh E, Yaghoutkar A, Hashemi H, Tabesh F, Khodadoostan M,Minakari M, Shavakhi S, Gholamrezaei A. The effects of multistrain probiotic compound on bismuth-containing quadruple therapy for Helicobacter pylori infection: a randomized placebo-c
  5. Karamali M, Dadkhah F, Sadrkhanlou M, et al. Effects of probiotic supplementation on glycaemic control and lipid profiles in gestational diabetes: a randomized, double-blind, placebo-controlled trial. Diabetes Metab 2016;42(4):234-41. PubMed
  6. Badehnoosh B, Karamali M, Zarrati M, et al. The effects of probiotic supplementation on biomarkers of inflammation, oxidative stress and pregnancy outcomes in gestational diabetes. J Matern Fetal Neonatal Med. 2018 May;31(9):1128-1136.
  7. Kumar S, Kumar R, Rohilla L, Jacob N, Yadav J, Sachdeva N. A high potency multi-strain probiotic improves glycemic control in children with new-onset type 1 diabetes mellitus: A randomized, double-blind, and placebo-controlled pilot study. Pediatr Diabete
  8. Shahriari A, Karimi E, Shahriari M, Aslani N, Khooshideh M, Arab A. The effect of probiotic supplementation on the risk of gestational diabetes mellitus among high-risk pregnant women: A parallel double-blind, randomized, placebo-controlled clinical trial PubMed
  9. Xiao SD, Zhang DZ, Lu H, et al. Multicenter, randomized, controlled trial of heat-killed Lactobacillus acidophilus LB in patients with chronic diarrhea. Adv Ther. 2003;20(5):253-60.
  10. Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed
  11. Ozer M, Goksu SY, Shahverdiani A, Mustafa M. Lactobacillus acidophilus-induced endocarditis and associated splenic abscess. Case Rep Infect Dis 2020;2020:1382709.
  12. Sadrin S, Sennoune S, Gout B, et al. A 2-strain mixture of Lactobacillus acidophilus in the treatment of irritable bowel syndrome: A placebo-controlled randomized clinical trial. Dig Liver Dis 2020;52(5):534-540. PubMed
  13. Stoffer JN, Slingsby TJ, Giuliari GP. Lactobacillus acidophilus endophthalmitis after intravitreal bevacizumab injection requiring intraocular lens explantation. Can J Ophthalmol 2022;57(1):e21-e22. PubMed
  14. Cukovic-Cavka S, Likic R, Francetic I, Rustemovic N, Opacic M, Vucelic B. Lactobacillus acidophilus as a cause of liver abscess in a NOD2/CARD15-positive patient with Crohn's disease. Digestion 2006;73(2-3):107-10.
  15. Hui J, Ren Y, Wang Y, Han Q. Lactobacillus acidophilus endophthalmitis postcataract operation: A case report with a literature review. Ocul Immunol Inflamm 2023.

See these in context on the Lactobacillus Acidophilus monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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