Interactions on record — worth a quick check against your medications. Based on 7 of 13 ingredients. Check your meds →
Dietary supplement

Prebiotic Formula Ingredients & Drug Interactions

by Health Plus

Prebiotic Formula label
See full label image
Capsule Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Prebiotic Formula against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Prebiotic Formula is a dietary supplement by Health Plus with 13 active ingredients. Its ingredients are commonly taken for digestive health and balance, diarrhea (including antibiotic-related), vaginal yeast and bacterial infections.Based on those ingredients, 2,198 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Slippery Elm, L. acidophilus, Burdock. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Prebiotic Formula by Health Plus

Ask about any prescription or over-the-counter medication and we check it for interactions with Prebiotic Formula by Health Plus — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Prebiotic Formula by Health Plus

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 13 active ingredients.
  • “Proprietary Probiotic Blend” is a proprietary blend — the label gives one combined amount (315 mg) without saying how much of each component you get.
  • “Proprietary Prebiotic Blend” is a proprietary blend — the label gives one combined amount (1,005 mg) without saying how much of each component you get.
  • “Proprietary Digestive Support Blend” is a proprietary blend — the label gives one combined amount (180 mg) without saying how much of each component you get.

Health Plus Prebiotic Formula is a 13-ingredient capsule containing active probiotics and prebiotics plus digestive enzymes. The probiotics include L. acidophilus and B. lactis/longum (which supports healthy gut bacteria), while the prebiotics — inulin, fructooligosaccharides, and arabinogalactan — feed the good bacteria already in your gut.

You'll also find L. plantarum, another probiotic strain. The digestive enzymes (phytase, xylanase, pectinase, hemicellulase, and glucanase) are meant to help break down food.

Burdock and slippery elm are herbal additions. The inactive ingredients are gelatin and maltodextrin.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: support digestive health and good bacteria.
  • We looked for evidence on: Antibiotic-associated diarrhea, Bacterial vaginosis, Clostridioides difficile infection, Colic, Constipation, Diarrhea — and 4 related terms.
  • The strongest evidence on file: Lactobacillus Acidophilus is rated "Possibly Effective" for Antibiotic-associated diarrhea (Natural Medicines).
  • Also on file: Lactobacillus Acidophilus is rated "Possibly Effective" for Bacterial vaginosis, Helicobacter pylori, Irritable bowel syndrome (IBS).
  • Also on file: Inulin is rated "Possibly Effective" for Constipation.

The evidence for this formula's ingredients is mixed and mostly modest. L. acidophilus is possibly effective for irritable bowel syndrome (IBS), Helicobacter pylori infection, antibiotic-associated diarrhea, and bacterial vaginosis.

Inulin is possibly effective for obesity, constipation, and diabetes. For most other conditions in the formula — acne, eczema, cough, inflammatory bowel disease, and the common cold — the evidence isn't established in the data we hold.

The digestive enzymes and arabinogalactan lack sufficient evidence to rate their effectiveness for any condition listed.

The evidence, ingredient by ingredient Lactobacillus Acidophilus Inulin Burdock Fructo-oligosaccharides (fos) Larch Arabinogalactan Slippery Elm Phytase

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 7 of the 7 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 7 of 7.
  • General safety write-ups exist for 7 of 7.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

L. acidophilus is generally well tolerated in healthy adults and children, though live microorganisms do carry a rare theoretical risk of serious infection in certain patients. Inulin, fructooligosaccharides, and arabinogalactan commonly cause gas, bloating, flatulence, and gastrointestinal cramps — especially at higher doses — but are otherwise well tolerated.

Slippery elm is generally well tolerated for short-term use, and burdock is likely safe when used as a food or short-term in healthy adults, though safety data are limited. Phytase may provoke allergic reactions in occupationally exposed people, though oral supplement risk is unclear.

Rare serious adverse effects reported with L. acidophilus include infection in compromised patients; burdock has rare allergic reactions and one case of liver injury (though other ingredients in that product may have been responsible); slippery elm pollen is an allergen and can cause contact dermatitis.

Side effects, ingredient by ingredient Lactobacillus Acidophilus Inulin Burdock Fructo-oligosaccharides (fos) Larch Arabinogalactan Slippery Elm Phytase

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 5 of the 7 matched ingredients can interact with medications — Burdock, Lactobacillus Acidophilus, Larch Arabinogalactan, Slippery Elm, Inulin.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; immunosuppressants / transplant drugs; diabetes medications.
  • For scale: 2,199 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, check your medications against these drug types: oral medications of any kind (slippery elm may slow absorption), antibiotics (L. acidophilus effectiveness may decrease), blood thinners and antiplatelet drugs (burdock may increase bleeding risk), diabetes medications (inulin may lower blood sugar), and immunosuppressants (arabinogalactan may interfere with them). All of these carry Moderate or Minor interactions with ingredients in this formula.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This formula may be worth considering if you're looking to support gut health with probiotics and prebiotics, but the most important step is checking it against your medications — especially if you're on oral drugs, antibiotics, blood thinners, diabetes medications, or immunosuppressants. Expect gas and bloating, particularly when you start or increase the dose.

Talk with your pharmacist before you begin, especially if you have a compromised immune system or are pregnant or breastfeeding.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 7 of 13 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated May 24, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Prebiotic Formula, straight from the product label.

Brand Health Plus
Barcode (UPC) 083502103530
Net contents 180 Capsule(s)
Market status On market
Date entered into DSLD May 24, 2023
DSLD ID 285755
Product type Other Combinations
Supplement form Capsule
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Prebiotic Formula by Health Plus, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
3 Capsule(s)
Maximum serving Sizes:
3 Capsule(s)
Servings per container
60
UPC/BARCODE
083502103530
IngredientAmount% DV
Calories5 Calorie(s)--
L. acidophilus0 NP--
Inulin0 NP--
Burdock0 NP--
Slippery Elm0 NP--
Xylanase0 NP--
Pectinase0 NP--
Phytase0 NP--
Proprietary Probiotic Blend315 mg--
Hemicellulase0 NP--
L. plantarum0 NP--
Fructooligosaccharides0 NP--
Glucanase0 NP--
Proprietary Prebiotic Blend1005 mg--
Arabinogalactin0 NP--
Proprietary Digestive Support Blend180 mg--
B. lactis/longum0 NP--

Other ingredients: Gelatin, Maltodextrin

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Precautions

Clear band and tamper evident seal under cap. Do not use if broken.

For California residents only. Warning: This product can expose you to lead, which is known to the state of California to cause birth defects or other reproductive harm. For more information, go to www.p65warnings.ca.gov.

Notice: Consult your physician if you have frequent diarrhea or if you are pregnant, nursing, taking medication or have a medical condition before using this product.

Keep this product out of reach of children.

Suggested/Recommended/Usage/Directions

Suggested use: Take 3 capsules twice daily. Prebiotic Formula may be taken continually to support overall health.

Formula

The millions of bacteria in our digestive tract are living organisms that need food to survive. They feed on prebiotic fibers, which are highly digestible to good bacteria. It is important to get enough prebiotics daily to feed the millions of microflora in your digestive tract. Prebiotic Formula contains prebiotics, probiotics, and digestive enzymes which work together to help maintain a well-functioning digestive system.

Prebiotics + Probiotics + Enzymes

General Statements

A simple promise It all starts with integrity. We never create anything that we wouldn't use ourselves or give to our own children. 100% Satisfaction Guarantee Customer Satisfaction

For detailed information on our proprietary blends visit us at www.healthplusinc.com/prebioticformula

Formulation

Gluten free

New look Same great formula

Food for your probiotics Promotes the growth of good bacteria

Seals/Symbols

Good Manufacturing Practice GMP Quality Quality Product

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Storage

Store below 72 degrees F (22 degrees C).

FDA Statement of Identity

Dietary Supplement

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Prebiotic Formula by Health Plus label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Prebiotic Formula label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Prebiotic Formula by Health Plus

These are the 13 active ingredients this product is made of. Select any to open its full monograph.

Serving size3 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Proprietary Probiotic Blend

315 mg per serving

Proprietary Prebiotic Blend

1005 mg per serving

Proprietary Digestive Support Blend

180 mg per serving

Other (inactive) ingredients: Gelatin, Maltodextrin. These complete the product’s ingredient list but are not active constituents.

Interaction report

Prebiotic Formula by Health Plus Drug Interactions

Want to check YOUR meds against Prebiotic Formula?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
2,198Drugs
2,170 Moderate 28 Minor

Ingredients driving the most interactions

Slippery Elm 2,022
L. acidophilus 182
Burdock 122
Arabinogalactin 121
Inulin 86

Individual Drug Interactions

The ingredients in Prebiotic Formula interact with 2,198 drugs. Click any drug to see the details.

5 of the 13 ingredients in Prebiotic Formula interact with drugs. Each result below shows which ingredient is responsible. Slippery Elm L. acidophilus Burdock Arabinogalactin Inulin

Each ingredient & the kinds of drugs it affects

For each ingredient in Prebiotic Formula with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Slippery Elm1 drug type · 2,022 drugs

Oral Drugs

Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Slippery elm inner bark contains mucilage, which may interfere with the absorption of orally administered drugs.

Likelihood Possible Evidence D
Slippery Elm full monograph & interactions

L. acidophilus1 drug type · 182 drugs

Antibiotic Drugs

Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L. acidophilus.
L. acidophilus preparations usually contain live and active organisms. Therefore, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and L. acidophilus preparations by at least two hours.

Likelihood Probable Evidence D
L. acidophilus full monograph & interactions

Burdock1 drug type · 122 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, taking burdock with anticoagulant or antiplatelet drugs might increase the risk of bleeding.

In vitro research shows that lignans from burdock reduce rabbit platelet aggregation by inhibiting platelet activating factor. This interaction has not been reported in humans.

Likelihood Possible Evidence D
Burdock full monograph & interactions

Arabinogalactin1 drug type · 121 drugs

Immunosuppressants

Theoretically, larch arabinogalactan might interfere with immunosuppression therapy due to immunostimulant effects. Immunosuppressant drugs include azathioprine (Imuran), basiliximab (Simulect), cyclosporine (Neoral, Sandimmune), daclizumab (Zenapax), muromonab-CD3 (OKT3, Orthoclone OKT3), mycophenolate (CellCept), tacrolimus (FK506, Prograf), sirolimus (Rapamune), prednisone (Deltasone, Orasone), corticosteroids (glucocorticoids), and other drugs.

Likelihood Possible Evidence D
Arabinogalactin full monograph & interactions

Inulin1 drug type · 86 drugs

Antidiabetes Drugs

Theoretically, inulin might increase the risk of hypoglycemia with antidiabetes drugs.
Some clinical research shows that inulin improves glycemic control in patients with diabetes; however, it is unclear if it has hypoglycemic effects.

Likelihood Unlikely Evidence D
Inulin full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Prebiotic Formula, from the product label.

Health Plus

See all Health Plus products
Name
Health Plus
City
Chino
State
CA
ZipCode
91710
Phone Number
(800)822-6225
Web Address
www.healthplusinc.com
Pharmacist Counseling Corner

Prebiotic Formula by Health Plus: Common Questions

Does Prebiotic Formula by Health Plus interact with any medications?
Yes. Based on its ingredients, Prebiotic Formula has a known interaction with 2,198 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Prebiotic Formula contains 13 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will this help my IBS?
L. acidophilus, one of the probiotics in this formula, is possibly effective for IBS based on the data we hold. It's not a guarantee, and results vary person to person, so talk with your doctor about whether it's right for you.
What should I expect when I first start taking it?
Gas, bloating, flatulence, and stomach cramps are common, especially at higher doses, because the prebiotics feed your gut bacteria. These usually ease as your digestive system adjusts. Starting with a lower dose and building up slowly can help.
Is it safe to take while pregnant?
Inulin and fructooligosaccharides are likely safe in pregnancy based on the data we hold, but there isn't enough safety information for most of the other ingredients — including burdock, which should be avoided during pregnancy. Talk with your doctor or pharmacist before taking this product if you're pregnant.
Can I take this with my antibiotic?
Not at the same time. Antibiotics can kill the live organisms in L. acidophilus, making the probiotic less effective. Space them apart — your pharmacist can recommend a schedule that works best.
What are the enzymes in here for?
The digestive enzymes — phytase, xylanase, pectinase, hemicellulase, and glucanase — are meant to help break down different types of food. The evidence for their effectiveness isn't established in the data we hold.
Does it have fillers?
Yes. The inactive ingredients are gelatin and maltodextrin, which are used to form and stabilize the capsule.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Prebiotic Formula is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Prebiotic Formula label
Go deeper

The Full Monographs Behind Prebiotic Formula’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Lactobacillus Acidophilus

Interacts with 182 drugs

Lactobacillus acidophilus is a 'friendly' bacterium used as a probiotic to support gut and vaginal health. It is generally well tolerated in healthy people, and there is reasonable evidence...

Read the full Lactobacillus Acidophilus monograph → Herb & supplement monograph

Inulin

Interacts with 86 drugs

Inulin is a type of plant fiber (a prebiotic) found naturally in foods like chicory root, onions, and garlic, and it is widely added to supplements and processed foods. It may help with regu...

Read the full Inulin monograph → Herb & supplement monograph

Burdock

Interacts with 122 drugs

Burdock is a traditional herb most often used for skin problems and as a so-called 'blood purifier,' but high-quality human studies are lacking and most claims are not well proven. It is wid...

Read the full Burdock monograph → Herb & supplement monograph

Fructo-oligosaccharides (fos)

Fructo-oligosaccharides (FOS) are a type of soluble fiber that acts as a prebiotic, meaning they feed the helpful bacteria in your gut. They are generally considered safe for most people in...

Read the full Fructo-oligosaccharides (fos) monograph → Herb & supplement monograph

Larch Arabinogalactan

Interacts with 121 drugs

Larch arabinogalactan is a soluble fiber from larch trees that is mainly used as a prebiotic and for immune support. Early research is interesting but limited, and most claims are not yet fi...

Read the full Larch Arabinogalactan monograph → Herb & supplement monograph

Slippery Elm

Interacts with 2,022 drugs

Slippery elm is a traditional herbal remedy made from the inner bark of a North American elm tree, used mainly to soothe sore throats and irritated digestive tracts. Its mucilage can coat an...

Read the full Slippery Elm monograph → Herb & supplement monograph

Phytase

Phytase is an enzyme that breaks down phytic acid (phytate) found in grains, beans, nuts, and seeds, which can free up minerals like iron, zinc, and calcium for absorption. It is widely used...

Read the full Phytase monograph →
Sources

Sources & How We Checked

Prebiotic Formula's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 67 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Lactobacillus Acidophilus 15 references
  1. Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
  2. Begtrup LM, de Muckadell OB, Kjeldsen J, Christensen RD, Jarbøl DE. Long-term treatment with probiotics in primary care patients with irritable bowel syndrome--a randomised, double-blind, placebo controlled trial. Scand J Gastroenterol 2013;48(10):1127-35 PubMed
  3. Chatterjee S, Kar P, Das T, Ray S, Gangulyt S, Rajendiran C, Mitra M. Randomised placebo-controlled double blind multicentric trial on efficacy and safety of Lactobacillus acidophilus LA-5 and Bifidobacterium BB-12 for prevention of antibiotic-associated
  4. Shavakhi A, Tabesh E, Yaghoutkar A, Hashemi H, Tabesh F, Khodadoostan M,Minakari M, Shavakhi S, Gholamrezaei A. The effects of multistrain probiotic compound on bismuth-containing quadruple therapy for Helicobacter pylori infection: a randomized placebo-c
  5. Karamali M, Dadkhah F, Sadrkhanlou M, et al. Effects of probiotic supplementation on glycaemic control and lipid profiles in gestational diabetes: a randomized, double-blind, placebo-controlled trial. Diabetes Metab 2016;42(4):234-41. PubMed
  6. Badehnoosh B, Karamali M, Zarrati M, et al. The effects of probiotic supplementation on biomarkers of inflammation, oxidative stress and pregnancy outcomes in gestational diabetes. J Matern Fetal Neonatal Med. 2018 May;31(9):1128-1136.
  7. Kumar S, Kumar R, Rohilla L, Jacob N, Yadav J, Sachdeva N. A high potency multi-strain probiotic improves glycemic control in children with new-onset type 1 diabetes mellitus: A randomized, double-blind, and placebo-controlled pilot study. Pediatr Diabete
  8. Shahriari A, Karimi E, Shahriari M, Aslani N, Khooshideh M, Arab A. The effect of probiotic supplementation on the risk of gestational diabetes mellitus among high-risk pregnant women: A parallel double-blind, randomized, placebo-controlled clinical trial PubMed
  9. Xiao SD, Zhang DZ, Lu H, et al. Multicenter, randomized, controlled trial of heat-killed Lactobacillus acidophilus LB in patients with chronic diarrhea. Adv Ther. 2003;20(5):253-60.
  10. Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed
  11. Ozer M, Goksu SY, Shahverdiani A, Mustafa M. Lactobacillus acidophilus-induced endocarditis and associated splenic abscess. Case Rep Infect Dis 2020;2020:1382709.
  12. Sadrin S, Sennoune S, Gout B, et al. A 2-strain mixture of Lactobacillus acidophilus in the treatment of irritable bowel syndrome: A placebo-controlled randomized clinical trial. Dig Liver Dis 2020;52(5):534-540. PubMed
  13. Stoffer JN, Slingsby TJ, Giuliari GP. Lactobacillus acidophilus endophthalmitis after intravitreal bevacizumab injection requiring intraocular lens explantation. Can J Ophthalmol 2022;57(1):e21-e22. PubMed
  14. Cukovic-Cavka S, Likic R, Francetic I, Rustemovic N, Opacic M, Vucelic B. Lactobacillus acidophilus as a cause of liver abscess in a NOD2/CARD15-positive patient with Crohn's disease. Digestion 2006;73(2-3):107-10.
  15. Hui J, Ren Y, Wang Y, Han Q. Lactobacillus acidophilus endophthalmitis postcataract operation: A case report with a literature review. Ocul Immunol Inflamm 2023.

See these in context on the Lactobacillus Acidophilus monograph →

Inulin 17 references
  1. Williams CM. Effects of inulin on lipid parameters in humans. J Nutr 1999 Jul;129(7 Suppl):1471S-3S. PubMed
  2. Pedersen A, Sandstrom B, Van Amelsvoort JM. The effect of ingestion of inulin on blood lipids and gastrointestinal symptoms in healthy females. Br J Nutr 1997;78:215-22. PubMed
  3. Cummings JH, Macfarlane GT, Englyst HN. Prebiotic digestion and fermentation. Am J Clin Nutr 2001;73:415S-420S. PubMed
  4. Bonnema AL, Kolberg LW, Thomas W, Slavin JL. Gastrointestinal tolerance of chicory inulin products. J Am Diet Assoc 2010;110(6):865-8. PubMed
  5. Dehghan P, Gargari BP, Jafar-Abadi MA, Aliasgharzadeh A. Inulin controls inflammation and metabolic endotoxemia in women with type 2 diabetes mellitus: a randomized-controlled clinical trial. Int J Food Sci Nutr 2014;65(1):117-23. PubMed
  6. Guess ND, Dornhorst A, Oliver N, Frost GS. A randomised crossover trial: the effect of inulin on glucose homeostasis in subtypes of prediabetes. Ann Nutr Metab 2016;68(1):26-34. PubMed
  7. Marteau P, Jacobs H, Cazaubiel M, Signoret C, Prevel JM, Housez B. Effects of chicory inulin in constipated elderly people: a double-blind controlled trial. Int J Food Sci Nutr 2011;62(2):164-70. PubMed
  8. Mensink MA, Frijlink HW, van der Voort Maarschalk K, Hinrichs WL. Inulin, a flexible oligosaccharide I: review of its physicochemical characteristics. Carbohydr Polym 2015;130:405-19. PubMed
  9. Slavin J, Feirtag J. Chicory inulin does not increase stool weight or speed up intestinal transit time in healthy male subjects. Food Funct. 2011;2(1):72-7. PubMed
  10. Micka A, Siepelmeyer A, Holz A, Theis S, Schön C. Effect of consumption of chicory inulin on bowel function in healthy subjects with constipation: a randomized, double-blind, placebo-controlled trial. Int J Food Sci Nutr. 2017;68(1):82-89. PubMed
  11. Smiljanec K, Mitchell CM, Privitera OF, Neilson AP, Davy KP, Davy BM. Pre-meal inulin consumption does not affect acute energy intake in overweight and obese middle-aged and older adults: A randomized controlled crossover pilot trial. Nutr Health. 2017;23 PubMed
  12. Cai X, Yu H, Liu L, et al. Milk powder co-supplemented with inulin and resistant dextrin improves glycemic control and insulin resistance in elderly type 2 diabetes mellitus: a 12-week randomized, double-blind, placebo-controlled trial. Mol Nutr Food Res PubMed
  13. Rao M, Gao C, Xu L, et al. Effect of inulin-type carbohydrates on insulin resistance in patients with type 2 diabetes and obesity: a systematic review and meta-analysis. J Diabetes Res. 2019;2019:5101423. PubMed
  14. Mitchell CM, Davy BM, Ponder MA, et al. Prebiotic Inulin Supplementation and Peripheral Insulin Sensitivity in adults at Elevated Risk for Type 2 Diabetes: A Pilot Randomized Controlled Trial. Nutrients 2021;13(9):3235. PubMed
  15. Li L, Li P, Xu L. Assessing the effects of inulin-type fructan intake on body weight, blood glucose, and lipid profile: A systematic review and meta-analysis of randomized controlled trials. Food Sci Nutr 2021;9(8):4598-4616. PubMed
  16. Ziaei R, Shahshahan Z, Ghasemi-Tehrani H, Heidari Z, Ghiasvand R. Effects of inulin-type fructans with different degrees of polymerization on inflammation, oxidative stress and endothelial dysfunction in women with polycystic ovary syndrome: A randomized,
  17. Risso D, Kaczmarczyk M, Laurie I, et al. Moderate intakes of soluble corn fibre or inulin do not cause gastrointestinal discomfort and are well tolerated in healthy children. Int J Food Sci Nutr 2022;73(8):1104-1115. PubMed

See these in context on the Inulin monograph →

Burdock 11 references
  1. Iwakami S, Wu JB, Ebizuka Y, Sankawa U. Platelet activating factor (PAF) antagonists contained in medicinal plants: lignans and sesquiterpenes. Chem Pharm Bull (Tokyo) 1992;40:1196-8. PubMed
  2. Sasaki Y, Kimura Y, Tsunoda T, Tagami H. Anaphylaxis due to burdock. Int J Dermatol 2003;42:472-3. PubMed
  3. Rhoads PM, Tong TG, Banner W Jr, Anderson R. Anticholinergic poisonings associated with commercial burdock root tea. J Toxicol Clin Toxicol 1984-85;22:581-4. PubMed
  4. Rodriguez P, Blanco J, Juste S, et al. Allergic contact dermatitis due to burdock (Arctium lappa). Contact Dermatitis 1995;33:134-5.
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Slippery Elm 3 references
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Phytase 7 references
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Fructo-oligosaccharides (fos) 6 references
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Larch Arabinogalactan 8 references
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  2. Kelly GS. Larch arabinogalactan: Clinical relevance of a novel immune-enhancing polysaccharide. Alt Med Rev 1999;4:96-103.
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See these in context on the Larch Arabinogalactan monograph →

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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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