No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

Biotin 1000 mcg Ingredients & Drug Interactions

by Spring Valley

Softgel Capsule Category: Vitamin
No known interaction
The interaction bottom line No known interaction

Biotin 1000 mcg is a dietary supplement by Spring Valley with 1 active ingredient. Its ingredients are commonly taken for hair growth and thinning hair, brittle nails, skin health.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Biotin 1000 mcg by Spring Valley

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This softgel contains one active ingredient: biotin, a B vitamin (also called vitamin B7). Biotin helps your body convert food into energy and plays a role in keeping your hair, skin, and nails healthy.

The other ingredients are inactive — soybean oil, gelatin, glycerin, yellow beeswax, and titanium dioxide — they make up the softgel capsule itself and help deliver the biotin.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: hair, skin, and nail health.
  • We looked for evidence on: Brittle nails, Biotin deficiency, Seborrheic dermatitis, hair loss, skin condition.
  • The strongest evidence on file: Biotin is rated "Likely Effective" for Biotin deficiency (Natural Medicines).
  • Also on file: Biotin is rated "Possibly Ineffective" for Seborrheic dermatitis.
  • Also on file: Biotin is rated "Insufficient Reliable Evidence To Rate" for Brittle nails.

Biotin is likely effective for treating biotin deficiency, which is rare but can happen in people with certain health conditions or on specific medications. For other uses, the evidence is weaker: it's possibly ineffective for multiple sclerosis and seborrheic dermatitis (a scaly skin condition), and there isn't enough reliable evidence to rate it for alopecia areata (patchy hair loss).

Most people take biotin as a supplement for hair, skin, and nail health, but that evidence isn't established in the data we hold.

The evidence, ingredient by ingredient Biotin

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Biotin is generally well tolerated, even at fairly high doses, because your body gets rid of excess in your urine. The main side effect reported at high doses is mild diarrhea — only a small number of people have experienced this.

There's one isolated case report of a rare inflammatory condition after taking high-dose biotin with other supplements, but no other similar cases exist, and it's unclear whether biotin was responsible. For pregnancy and breastfeeding, normal dietary and supplement amounts are likely safe.

However, the product label advises checking with your doctor before taking high-dose biotin supplements during these times. If you're pregnant or nursing and considering this product, talk it over with your own doctor or pharmacist first.

Side effects, ingredient by ingredient Biotin

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for the biotin in this product.

The bottom line

Scorecard at a glanceFully disclosed formula with clinical evidence supporting its stated purpose. No medication interactions are currently documented, and safety information is well characterized.

This is a straightforward biotin supplement with no known drug interactions. It's most clearly useful if you have a biotin deficiency, and it's generally well tolerated at the dose in this bottle.

If you're taking it for hair, skin, or nail health, that benefit isn't proven in the data we hold. Talk with your own doctor or pharmacist about whether it makes sense for you.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jan 7, 2019.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Biotin 1000 mcg, straight from the product label.

Brand Spring Valley
Barcode (UPC) 681131928823
Net contents 150 Softgel(s)
Market status On market
Date entered into DSLD Jan 7, 2019
DSLD ID 184057
Product type Vitamin
Supplement form Softgel Capsule
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Biotin 1000 mcg by Spring Valley, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Softgel(s)
Maximum serving Sizes:
1 Softgel(s)
UPC/BARCODE
681131928823
IngredientAmount% DV
Biotin1000 mcg333%

Other ingredients: Soybean Oil, Gelatin, Glycerin, yellow Beeswax, Titanium Dioxide

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Biotin 1000 mcg per softgel

Biotin is a B vitamin that is essential for healthy energy metabolism and also supports healthy hair, skin, and nails.

General Statements

Hair/Skin/Nail health

Quality guaranteed

FDA Statement of Identity

Dietary Supplement

Formulation

No Gluten, Yeast, Wheat, Milk, or Milk Derivatives, Lactose, Sugar, Preservatives, Artificial Flavor, Sodium (less than 5 mg per serving)

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Suggested/Recommended/Usage/Directions

Suggested use: Adults, take one softgel one to five times daily, preferably with a meal.

Precautions

Warning: Please consult your doctor before use. Stop use and consult your doctor is any adverse reactions occur.

Keep out of reach of children.

For your protection, do not use if seal under cap is broken or missing.

Storage

Store at room temperature. Keep bottle tightly closed.

General

Item No. 57778 B50709W 01A 108234

See for yourself

Biotin 1000 mcg by Spring Valley label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Biotin 1000 mcg by Spring Valley

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Softgel(s) Dosage formSoftgel Capsule Amounts shown are per serving.

Biotin

No known
interactions
1000 mcg per serving Form: D-Biotin

Biotin (vitamin B7) is a water-soluble vitamin your body needs to turn food into energy and to support healthy hair, skin, and nails. Most people get...

Biotin monograph & interactions

Other (inactive) ingredients: Soybean Oil, Gelatin, Glycerin, Yellow Beeswax, Titanium Dioxide. These complete the product’s ingredient list but are not active constituents.

Interaction report

Biotin 1000 mcg by Spring Valley Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Biotin 1000 mcg. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Biotin 1000 mcg, from the product label.

Spring Valley

See all Spring Valley products
Name
Wal-Mart Stores, Inc.
City
Bentonville
State
AR
ZipCode
72716
Phone Number
1-866-251-1662
Web Address
Walmart.com/springvalley
Pharmacist Counseling Corner

Biotin 1000 mcg by Spring Valley: Common Questions

Does Biotin 1000 mcg by Spring Valley interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Biotin 1000 mcg. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Biotin 1000 mcg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will biotin help my hair grow or my nails get stronger?
The evidence that biotin improves hair, skin, or nail health isn't established in the data we hold. Biotin is well known for these uses and many people take it for them, but we can't confirm from our records that it works for those purposes. Your doctor or a dermatologist might have better insight based on your specific situation.
Is this safe to take while I'm pregnant?
Biotin is rated likely safe during pregnancy at normal dietary and supplement amounts. However, this product is 1000 mcg, which is a supplement dose — higher than you'd get from food. The safety data advises checking with your doctor before taking high-dose biotin during pregnancy, so check with your own healthcare provider first.
Can I take this if I have a vitamin B deficiency?
Biotin is likely effective for treating biotin deficiency specifically. If you think you have a B vitamin deficiency, talk with your doctor — they can test you and tell you whether biotin (and how much) is right for you.
What are the side effects?
Biotin is generally well tolerated. At the dose in this bottle (1000 mcg), side effects are unlikely. At much higher doses, mild diarrhea has been rarely reported. One isolated case of an inflammatory condition was reported after very high-dose biotin with other supplements, but there have been no other similar cases.
Does biotin interact with my medications?
No interactions are documented in our data for biotin. That said, it's always smart to run your exact medication list through the tool on this page or ask your pharmacist — they know your full picture better than any general resource can.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Biotin 1000 mcg is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Biotin 1000 mcg label
Go deeper

The Full Monographs Behind Biotin 1000 mcg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Biotin 1000 mcg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 4 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Biotin 4 references
  1. Debourdeau PM, Djezzar S, Estival JL, et al. Life-threatening eosinophilic pleuropericardial effusion related to vitamins B5 and H. Ann Pharmacother 2001;35:424-6. DOI
  2. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline (2000). Washington, DC: National Academy Press, 2000. Available at: http://b
  3. Mock DM, Quirk JG, Mock NI. Marginal biotin deficiency during normal pregnancy. Am J Clin Nutr 2002;75:295-9. PubMed
  4. Sedel F, Papeix C, Bellanger A, Touitou V, Lebrun-Frenay C, Galanaud D, et al. High doses of biotin in chronic progressive multiple sclerosis: a pilot study.Mult Scler Relat Disord. 2015;4(2):159-69. doi: 10.1016/j.msard.2015.01.005. PubMed

See these in context on the Biotin monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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