No known drug interactions for the matched ingredients — not a guarantee none exist. Based on 1 of 2 ingredients. Check your meds →
Dietary supplement

Biotin plus Keratin Ingredients & Drug Interactions

by up&up

Tablet Or Pill Category: Other Combinations
No known interaction
The interaction bottom line No known interaction

Biotin plus Keratin is a dietary supplement by up&up with 2 active ingredients. Its ingredients are commonly taken for hair growth and thinning hair, brittle nails, skin health.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Biotin plus Keratin by up&up

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains 2 active ingredients: biotin and keratin. Biotin is a B vitamin that supports the health of hair, skin, and nails, and it's used to treat biotin deficiency.

Keratin is a structural protein that's also marketed for hair and skin support, though we don't hold interaction data for it. The product also includes inactive ingredients — microcrystalline cellulose, dicalcium phosphate, and hydroxypropyl methylcellulose — which are fillers and binders.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: promote healthy hair, skin, and nails.
  • We looked for evidence on: Biotin deficiency, Brittle nails, hair loss, nail health, skin condition.
  • The strongest evidence on file: Biotin is rated "Likely Effective" for Biotin deficiency (Natural Medicines).
  • Also on file: Biotin is rated "Insufficient Reliable Evidence To Rate" for Brittle nails.

Biotin is likely effective for treating biotin deficiency. For other uses, the evidence is less clear: it's rated possibly ineffective for seborrheic dermatitis and multiple sclerosis, and there's insufficient reliable evidence to rate it for alopecia areata (hair loss in patches).

We don't hold effectiveness data for keratin in our system.

The evidence, ingredient by ingredient Biotin

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Biotin is generally well tolerated, even at fairly high doses, because your body removes excess in the urine. High-dose biotin has rarely been linked to mild diarrhea — two patients taking 300 mg daily reported transient mild diarrhea.

One case report described a possible reaction to high-dose biotin combined with other supplements, but no similar cases have been reported since, and it's unclear whether biotin was the cause. Amounts from food and prenatal vitamins are appropriate, but check with your doctor before taking high-dose biotin supplements.

Biotin is likely safe in pregnancy and lactation.

Side effects, ingredient by ingredient Biotin

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for the ingredients we could check. Talk with your doctor or pharmacist before starting, especially if you take prescription medications regularly.

The bottom line

Scorecard at a glanceFully disclosed formula with clinical evidence supporting its stated purpose. No medication interactions are currently documented, and safety information is well characterized.

This product makes sense if you're treating a biotin deficiency or looking to support hair and skin health with biotin and keratin. If you're pregnant, breastfeeding, or taking any prescription medications, talk with your doctor or pharmacist first — especially before taking high-dose biotin.

No interactions are documented for biotin, but keratin wasn't checked, so confirm your exact medications with your healthcare provider.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Nov 21, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Biotin plus Keratin, straight from the product label.

Brand up&up
Barcode (UPC) 079524867215
Net contents 120 Tablet(s)
Market status On market
Date entered into DSLD Nov 21, 2020
DSLD ID 240382
Product type Other Combinations
Supplement form Tablet Or Pill
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Biotin plus Keratin by up&up, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Tablet(s)
Maximum serving Sizes:
1 Tablet(s)
UPC/BARCODE
079524867215
IngredientAmount% DV
Biotin10000 mcg33333%
Keratin100 mg--

Other ingredients: Microcrystalline Cellulose, Dicalcium Phosphate, Hydroxypropyl Methylcellulose, Contains 2% or less of

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Biotin plus Keratin Biotin 10000 mcg Keratin 100 mg

Formulation

May help promote healthy hair, skin, and nails Restore

Biotin is a water-soluble B vitamin that is involved in the metabolism of protein, fats, and carbohydrates. It may also help support healthy hair, skin and nails. Keratin may help support the structural integrity of hair, skin and nails.

No artificial dyes or flavors No gluten No lactose

Made in China. Packaged, and quality assured in the USA.

FDA Statement of Identity

Dietary Supplement

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Brand IP Statement(s)

2018 Target Brands, Inc.

Suggested/Recommended/Usage/Directions

Suggested use: Adults, take one tablet daily with food as a dietary supplement.

Precautions

Keep out of the reach of children.

Caution: Pregnant or nursing women, individuals taking medication(s) or persons who have a health condition should consult their physician before using this product.

Safety-sealed. Do not use if printed seal under cap is cut, torn, or missing.

Storage

Store at 15 degrees - 30 degrees C (59 degrees - 86 degrees F).

General Statements

Tablet color may vary.

See for yourself

Biotin plus Keratin by up&up label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Biotin plus Keratin by up&up

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Tablet(s) Dosage formTablet Or Pill Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Biotin

No known
interactions
10000 mcg per serving

Biotin (vitamin B7) is a water-soluble vitamin your body needs to turn food into energy and to support healthy hair, skin, and nails. Most people get...

Biotin monograph & interactions

Keratin

100 mg per serving

Other (inactive) ingredients: Microcrystalline Cellulose, Dicalcium Phosphate, Hydroxypropyl Methylcellulose, Contains 2% or less of. These complete the product’s ingredient list but are not active constituents.

Interaction report

Biotin plus Keratin by up&up Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Biotin plus Keratin. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Biotin plus Keratin, from the product label.

up&up

See all up&up products
Name
Target Corp.
City
Minneapolis
State
MN
Phone Number
1-800-910-6874
Pharmacist Counseling Corner

Biotin plus Keratin by up&up: Common Questions

Does Biotin plus Keratin by up&up interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Biotin plus Keratin. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Biotin plus Keratin contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is biotin safe to take while pregnant or breastfeeding?
Biotin is rated likely safe in pregnancy and lactation. Amounts from food and prenatal vitamins are appropriate, but check with your doctor before taking high-dose biotin supplements — they'll advise what's right for you.
What does biotin actually do?
Biotin is a B vitamin that helps your body process nutrients and is marketed for hair, skin, and nail health. It's likely effective for treating biotin deficiency specifically. For other uses like seborrheic dermatitis or hair loss, the evidence is weaker or still being studied.
Can biotin cause side effects?
High-dose biotin is generally well tolerated. The main side effect reported is mild diarrhea, which was transient — it happened in two patients taking 300 mg daily. One isolated case report linked high-dose biotin with another supplement to a respiratory reaction, but no similar cases have occurred since.
Will this help my hair grow or stop hair loss?
Biotin is marketed for hair health, but the evidence for alopecia areata (patchy hair loss) is rated insufficient — we don't have enough reliable data to say whether it works. If you're dealing with hair loss, talk with your doctor about what might help.
Is there anything in this product I should avoid if I take medications?
No interactions are documented for biotin. We couldn't check keratin, but no safety concerns have been raised. Still, run your exact medications through the search tool on this page and confirm with your doctor or pharmacist before you start — especially if you take prescription drugs regularly.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Biotin plus Keratin is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Biotin plus Keratin label
Go deeper

The Full Monographs Behind Biotin plus Keratin’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Biotin plus Keratin's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 4 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Biotin 4 references
  1. Debourdeau PM, Djezzar S, Estival JL, et al. Life-threatening eosinophilic pleuropericardial effusion related to vitamins B5 and H. Ann Pharmacother 2001;35:424-6. DOI
  2. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline (2000). Washington, DC: National Academy Press, 2000. Available at: http://b
  3. Mock DM, Quirk JG, Mock NI. Marginal biotin deficiency during normal pregnancy. Am J Clin Nutr 2002;75:295-9. PubMed
  4. Sedel F, Papeix C, Bellanger A, Touitou V, Lebrun-Frenay C, Galanaud D, et al. High doses of biotin in chronic progressive multiple sclerosis: a pilot study.Mult Scler Relat Disord. 2015;4(2):159-69. doi: 10.1016/j.msard.2015.01.005. PubMed

See these in context on the Biotin monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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