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Dietary supplement

Black Elderberry Honey Alcohol-free Extract Ingredients & Drug Interactions

by Oregon's Wild Harvest

Liquid Category: Botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Black Elderberry Honey Alcohol-free Extract is a dietary supplement by Oregon's Wild Harvest with 1 active ingredient. Its ingredients are commonly taken for colds, flu (influenza), other respiratory infections.Based on those ingredients, 121 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Black Elderberry. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Black Elderberry Honey Alcohol-free Extract by Oregon's Wild Harvest

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: black elderberry extract in a liquid form. The extract is prepared from ripe elderberries and mixed with glycerin, honey, raspberry juice concentrate, and citrus extract as inactive ingredients (the carriers and sweeteners that make up the formulation).

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Elderberry product and its label doesn't state a use — see Elderberry's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence for black elderberry is not yet established for the conditions it's often used for. The data we hold shows insufficient reliable evidence to rate it for hay fever, heart disease, chronic fatigue, COPD, brain function, or respiratory tract infections.

That doesn't mean it doesn't work — it means large, well-designed studies haven't proven it yet.

The evidence, ingredient by ingredient Elderberry

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Properly cooked elderberry products like this one are generally well tolerated. The main risk is raw or unripe berries, seeds, leaves, or bark, which contain natural toxins that can cause nausea, vomiting, diarrhea, dizziness, and other effects — but cooking eliminates those toxins, and this product is a prepared extract, not raw plant material.

A few cases of nausea and vomiting have been reported, though it's sometimes unclear whether elderberry alone or a combination product was responsible. There is one case report of autoimmune hepatitis (liver inflammation) in someone with an underlying autoimmune condition who took elderberry for years, which resolved after stopping the supplement.

During pregnancy and breastfeeding, there isn't enough reliable safety information, so the safety data advises against use during these times.

Side effects, ingredient by ingredient Elderberry

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Elderberry.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: immunosuppressants / transplant drugs.
  • For scale: 121 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check with your pharmacist before using this if you take immunosuppressants (drugs that weaken your immune system after transplant or for autoimmune disease) or pazopanib (a cancer medication) — both carry Moderate interaction concerns with black elderberry.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Black elderberry extract is generally well tolerated as a prepared product, but evidence for what it actually does is limited. It's most important to avoid it if you take immunosuppressants or pazopanib.

If you have an autoimmune condition or liver disease, talk with your pharmacist or doctor first.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Sep 25, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Black Elderberry Honey Alcohol-free Extract, straight from the product label.

Brand Oregon's Wild Harvest
Barcode (UPC) 706195003375
Net contents 4 Fluid Ounce(s); 118 mL
Market status On market
Date entered into DSLD Sep 25, 2024
DSLD ID 317150
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Women (not pregnant or lactating), Organic, Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Black Elderberry Honey Alcohol-free Extract by Oregon's Wild Harvest, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
5 mL
Maximum serving Sizes:
5 mL
Servings per container
24
UPC/BARCODE
706195003375
IngredientAmount% DV
Calories17 Calorie(s)--
Total Carbohydrates5.4 Gram(s)1.7%
Black Elderberry1400 mg--

Other ingredients: Glycerin, Honey, Raspberry juice concentrate, Citrus Extract

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Organic to our roots As certified organic farmers since 1994, our regenerative practices heal the land and water and sequester carbon from the atmosphere, while ensuring that pure, potent herbal medicine is available today and for future generations. Peace.

Formulation

Free from: Gluten, dairy and soy allergens.

Immune system support

Alcohol-free extract Non GMO GF (Gluten free)

USDA Organic

Herbs extracted in organic alcohol, alcohol removed.

Certified Organic by Oregon Tilth

Precautions

Caution: Keep out of reach of children.

If taking medication consult with a healthcare professional before use. Do not take if pregnant or nursing.

Discontinue use if unusual symptoms occur.

Warning: Do not give any honey products to infants less than one year old.

Do not exceed recommended dose.

FDA Disclaimer Statement

This statement had not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Brand IP Statement(s)

Oregon's Wild Harvest Since 1994

FDA Statement of Identity

Herbal Supplement

Seals/Symbols

USDA Organic

Oregon Tilth Certified Organic (OTCO)

Suggested/Recommended/Usage/Directions

Suggested Use: Take 1 tsp (5mL) 1 to 3 times daily. May be taken in warm water, juice or herbal tea of preference.

Shake well.

Storage

Store upright in a cool, dry place.

See for yourself

Black Elderberry Honey Alcohol-free Extract by Oregon's Wild Harvest label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Black Elderberry Honey Alcohol-free Extract by Oregon's Wild Harvest

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size5 mL Dosage formLiquid Servings per container24 Amounts shown are per serving.

Black Elderberry

Interacts with
121 drugs
1400 mg per serving Form: Sambucus nigra

Elderberry is a popular herbal supplement, mainly taken to help with colds and flu. Some small studies suggest it may modestly shorten cold or flu sym...

Black Elderberry monograph & interactions

Other (inactive) ingredients: Glycerin, Honey, Raspberry juice concentrate, Citrus Extract. These complete the product’s ingredient list but are not active constituents.

Interaction report

Black Elderberry Honey Alcohol-free Extract by Oregon's Wild Harvest Drug Interactions

Want to check YOUR meds against Black Elderberry Honey Alcohol-free Extract?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
121Drugs
121 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Black Elderberry Honey Alcohol-free Extract with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Black Elderberry2 drug types · 121 drugs

Immunosuppressants

Theoretically, elderberry might interfere with immunosuppressant therapy due to its immunostimulant activity.
Elderberry has immunostimulant activity, increasing the production of cytokines, including interleukin and tumor necrosis factor.

Likelihood Possible Evidence B
Pazopanib (Votrient)

Theoretically, elderberry might interact with pazopanib, potentially increasing the risk of adverse effects.
In one case, a 65-year-old patient taking pazopanib for 4 weeks for soft-tissue sarcoma developed severe nausea, loose stools, and elevated alanine transaminase and aspartate transaminase levels and was diagnosed with grade 3 liver injury. The patient reported taking elderberry supplements for 2 years, dose unspecified, and was also taking a multivitamin and a calcium supplement. The patient's symptoms and liver enzyme levels improved upon discontinuation of pazopanib and all supplements. Pazopanib treatment was re-initiated, at a lower dose, with no further evidence of liver injury. It was unclear in this case report if the elderberry supplements were derived from the berry, the flower, or the combination.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Black Elderberry Honey Alcohol-free Extract, from the product label.

Oregon's Wild Harvest

See all Oregon's Wild Harvest products
Name
Oregon's Wild Harvest
City
Redmond
State
OR
ZipCode
97756
Phone Number
800-316-6869
Web Address
oregonswildharvest.com
Pharmacist Counseling Corner

Black Elderberry Honey Alcohol-free Extract by Oregon's Wild Harvest: Common Questions

Does Black Elderberry Honey Alcohol-free Extract by Oregon's Wild Harvest interact with any medications?
Yes. Based on its ingredients, Black Elderberry Honey Alcohol-free Extract has a known interaction with 121 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Black Elderberry Honey Alcohol-free Extract contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is this safe to take if I'm pregnant or breastfeeding?
There isn't enough reliable safety information about elderberry during pregnancy and breastfeeding, so the data advises against it. Talk with your doctor or pharmacist about what's right for you in these situations.
Will this help me avoid colds or the flu?
The evidence for black elderberry on respiratory tract infections is not yet established in the data we hold. There isn't enough reliable proof yet that it prevents or shortens cold or flu.
What's in this product besides the elderberry?
The active ingredient is black elderberry extract. The inactive ingredients are glycerin, honey, raspberry juice concentrate, and citrus extract — these are the liquid base and sweeteners.
What side effects can elderberry cause?
Properly prepared elderberry extracts like this one are generally well tolerated and most people don't report side effects. If they do occur, they're usually nausea or vomiting. Raw or unripe berries or plant parts can cause stronger problems like severe diarrhea or dizziness, but this product is a cooked extract, not raw plant material.
Can I take this if I have liver disease or an autoimmune condition?
There's one case report of someone with an underlying autoimmune disease who developed liver inflammation after taking elderberry for years. If you have liver disease or an autoimmune condition, talk with your pharmacist or doctor first — they can help you decide if it's right for you.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Black Elderberry Honey Alcohol-free Extract is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Black Elderberry Honey Alcohol-free Extract label
Go deeper

The Full Monographs Behind Black Elderberry Honey Alcohol-free Extract’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Black Elderberry Honey Alcohol-free Extract's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 6 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Elderberry 6 references
  1. Barak V, Halperin T, Kalickman I. The effect of Sambucol, a black elderberry-based, natural product, on the production of human cytokines: I. Inflammatory cytokines. Eur Cytokine Netw 2001;12:290-6..
  2. Elderberry (Sambucus species). The Poison Plant Patch, Novia Scotia Museum, 2007. Available at: http://museum.gov.ns.ca/poison/?section=species&id=117 (Accessed 16 October 2009).
  3. European elder. Canadian Poisonous Plants Information System. Available at: http://www.cbif.gc.ca/pls/pp/ppack.jump?p_null=all&p_psn=121&p_type=all&p_sci=comm&p_x=px (Accessed 16 October 2009).
  4. Raus K, Pleschka S, Klein P, Schoop R, Fisher P. Effect of an echinacea-based hot drink versus oseltamivir in Influenza treatment: a randomized, double-blind, double-dummy, multicenter, noninferiority clinical trial. . Curr Ther Res Clin Exp. 2015;20;77:6 PubMed
  5. Ramachandran A, Antala D, Pudasainee P, Panginikkod S, Gupta H. A Plausible Association Between the Use of Elderberry and Autoimmune Hepatitis. Cureus 2022;14(4):e24250. PubMed
  6. Agarwal N, Mangla A. Elderberry interaction with pazopanib in a patient with soft-tissue sarcoma: A case report and literature review. Mol Clin Oncol 2024;20(5):36. PubMed

See these in context on the Elderberry monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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