Bladder Support Ingredients & Drug Interactions
by Herbal Terra
What is this page for?
First and foremost: checking Bladder Support against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Bladder Support is a dietary supplement by Herbal Terra with 5 active ingredients. Its ingredients are commonly taken for urinary tract and bladder problems, mild fluid retention (diuretic), kidney and prostate concerns.Based on those ingredients, 2,146 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are certified organic Marshmallow extract, certified organic Uva Ursi extract, certified organic Cornsilk extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Bladder Support by Herbal Terra
Ask about any prescription or over-the-counter medication and we check it for interactions with Bladder Support by Herbal Terra — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Bladder Support by Herbal Terra
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
Bladder Support has five active herbal extracts: certified organic corn silk, couchgrass (also called wheatgrass), marshmallow, uva ursi, and yarrow. Each plays a traditional role in herbal bladder and urinary-tract support.
The product also contains menstruum, a botanical solvent used to extract and preserve the herbs in liquid form.
Does it work?
Leans against
The evidence supporting these ingredients for bladder and urinary health isn't established in the data we hold. Corn silk, couchgrass, marshmallow, uva ursi, and yarrow all have insufficient reliable evidence to rate for their common uses — meaning we don't yet have robust clinical trial data proving they work for any of those purposes.
How safe is it?
Well-documented data
Corn silk and marshmallow are generally well tolerated for short-term use, but long-term safety data are limited. The most common side effects from corn silk are low potassium and low sodium (hypokalemia and hyponatremia), especially with prolonged use or if combined with diuretics.
Uva ursi is safe at low doses short-term but can be toxic at high doses; at very high doses (30 grams or more), it may be life-threatening. It typically causes stomach upset, nausea, vomiting, and diarrhea.
Couchgrass (wheatgrass) is generally well tolerated but quality and contamination concerns warrant caution; it's also a major food allergen for wheat-sensitive individuals. Yarrow can cause skin reactions, dermatitis, and rarely airway reactions when handled topically.
Pregnancy: the safety data advise against corn silk, marshmallow, and uva ursi during pregnancy; yarrow is traditionally avoided because it may affect the uterus. Breastfeeding: safety data aren't sufficient for any of these ingredients, so speak with your doctor or pharmacist before use while nursing.
Meds to double-check
Moderate interaction found
Before taking this product, double-check if you use lithium (Moderate risk of toxicity from three ingredients), antihypertensive drugs like ACE inhibitors or beta-blockers (corn silk may lower blood pressure further), diabetes medications (corn silk and couchgrass may lower blood sugar), diuretics (corn silk increases potassium and sodium loss), blood thinners like warfarin (corn silk contains vitamin K), corticosteroids (corn silk increases potassium loss), or medications your liver breaks down via CYP1A2, CYP2C19, or CYP3A4 enzymes. Also check any drugs that are glucuronidated or transported by P-glycoprotein, since uva ursi may affect their metabolism.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with graded evidence leaning against its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
Bladder Support is an herbal blend with a long list of potential drug interactions, especially with lithium, blood pressure medications, diabetes drugs, diuretics, and blood thinners. If you take any prescription or over-the-counter medications, check them against this product using the tool on this page before you buy.
Talk to your pharmacist or doctor — especially if you're pregnant, nursing, or taking lithium.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 5 of 5 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Sep 25, 2020.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Bladder Support, straight from the product label.
| Brand | Herbal Terra |
|---|---|
| Barcode (UPC) | 0606595868690 |
| Net contents | 4 Fluid Ounce(s); 120 mL |
| Market status | On market |
| Date entered into DSLD | Sep 25, 2020 |
| DSLD ID | 234018 |
| Product type | Botanical |
| Supplement form | Liquid |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Organic, Gluten Free, Sugar Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Bladder Support by Herbal Terra, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Proprietary Herbal Extracts Blend | 970 mg | -- |
| certified organic Cornsilk extract | 0 NP | -- |
| certified organic Couchgrass extract | 0 NP | -- |
| certified organic Marshmallow extract | 0 NP | -- |
| certified organic Uva Ursi extract | 0 NP | -- |
| certified organic Yarrow extract | 0 NP | -- |
Other ingredients: Menstruum
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula
Certified organic: Cornsilk (Zea mays) dried silk (Kenya), Couchgrass (Elymis repens) dried root (Poland), Marshmallow (Althaea officinalis) dried root (USA), Uva ursi (Arctostaphylos uva ursi) dried herb (Croatia), Yarrow (Archillea millefolium) dried herb (Bulgaria).
Suggested/Recommended/Usage/Directions
Direction Shake well before use. Adults take up to 30 drops (1 mL, one full squeeze of the dropper bulb) in 3-4 fl. oz of juice or water up to 4 times a day. We recommend to seek expert medical advice before taking this or any other herbal supplements.
FDA Disclaimer Statement
Notice This product has not been evaluated by the FDA and is not intended to diagnose, treat, cure, or prevent any disease.
Formulation
Manufactured in the USA in an FDA registered facility
Sugar free
A herbal extract that is used to reduce bladder problems.
Dried herb/menstruum ratio: 1:3 Expertly extracted Laboratory tested 330 mg/1 mL Premium product Super concentrated liquid herbal extract
Non GMO
No artificial ingredients, GMO, gluten, color additives, fillers, preservatives or binders. Natural Gluten Free
Certified organic: Cornsilk (Zea mays) dried silk (Kenya), Couchgrass (Elymis repens) dried root (Poland), Marshmallow (Althaea officinalis) dried root (USA), Uva ursi (Arctostaphylos uva ursi) dried herb (Croatia), Yarrow (Archillea millefolium) dried herb (Bulgaria).
Precautions
Caution May have contraindications.
Do not use if you are allergic to any ingredients.
Consult a physician before using during pregnancy, if nursing, or if you are on any medications.
Keep out of the reach of children.
Storage
Store in a cool, dry, dark place.
FDA Statement of Identity
Herbal Supplement
Seals/Symbols
Made in USA Made in an FDA registered facility Natural Gluten Free 100% Natural guaranteed
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Bladder Support by Herbal Terra label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Bladder Support by Herbal Terra
These are the 5 active ingredients this product is made of. Select any to open its full monograph.
Serving size1 mL Dosage formLiquid Servings per container120 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Proprietary Herbal Extracts Blend
Other (inactive) ingredients: Menstruum. These complete the product’s ingredient list but are not active constituents.
Bladder Support by Herbal Terra Drug Interactions
HelloPharmacist Interaction Report
Bladder Support by Herbal Terra contains five herbal extracts, and we've documented interactions affecting a broad range of medications.
The most serious concern is with lithium — three of the ingredients (marshmallow, uva ursi, and yarrow) may theoretically reduce its excretion and raise its blood levels, which could require a dose adjustment to avoid toxicity.
Read the full breakdown — every affected drug type, severity by severity
Corn silk extract poses Moderate interactions with blood pressure drugs (antihypertensives), diabetes medications, diuretics, and blood thinners like warfarin. It may lower blood pressure and blood sugar, and contains vitamin K, which can interfere with warfarin if intake varies day to day.
It also increases potassium loss, which is a concern if you're taking corticosteroids. Couchgrass extract (wheatgrass) may lower blood sugar further with diabetes drugs and may affect how your liver breaks down certain medications (CYP1A2 substrates).
Uva ursi extract interacts with several drug-processing pathways in your liver (CYP2C19 and CYP3A4 substrates) and with glucuronidated drugs; these are Moderate interactions in theory, though not yet seen in humans.
Marshmallow extract carries a Minor interaction with general oral medications — its mucilage may slow absorption, so space it 30–60 minutes apart from other drugs. Altogether, these interactions span 2,127 individual medications.
Before you start, run your exact prescriptions and over-the-counter drugs through the search tool on this page.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Bladder Support?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Bladder Support interact with 2,146 drugs. Click any drug to see the details.
5 of the 5 ingredients in Bladder Support interact with drugs. Each result below shows which ingredient is responsible. certified organic Marshmallow extract certified organic Uva Ursi extract certified organic Cornsilk extract certified organic Couchgrass extract certified organic Yarrow extract
AzilsartanEdarbi
How Azilsartan interacts with Bladder Support — through 2 ingredients. Tap an ingredient for the detail:
Certified Organic Cornsilk ExtractAntihypertensive Drugs Moderate
Interaction Summary
Taking corn silk extract with antihypertensive drugs might increase the risk of hypotension.
Read the full Certified Organic Cornsilk Extract + Azilsartan interactionCertified Organic Marshmallow ExtractOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Certified Organic Marshmallow Extract + Azilsartan interactionAzilsartan, ChlorthalidoneEdarbyclor
How Azilsartan, Chlorthalidone interacts with Bladder Support — through 2 ingredients. Tap an ingredient for the detail:
Certified Organic Cornsilk ExtractAntihypertensive Drugs, Diuretic Drugs Moderate
Interaction Summary
Taking corn silk extract with antihypertensive drugs might increase the risk of hypotension.
Read the full Certified Organic Cornsilk Extract + Azilsartan, Chlorthalidone interactionCertified Organic Marshmallow ExtractOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Certified Organic Marshmallow Extract + Azilsartan, Chlorthalidone interactionBazedoxifene Acetate, Conjugated EstrogensDuavee
How Bazedoxifene Acetate, Conjugated Estrogens interacts with Bladder Support — through 2 ingredients. Tap an ingredient for the detail:
Certified Organic Uva Ursi ExtractGlucuronidated Drugs, P-glycoprotein Substrates +1 Moderate
Interaction Summary
Theoretically, uva ursi may increase levels of drugs metabolized by glucuronidation.
Read the full Certified Organic Uva Ursi Extract + Bazedoxifene Acetate, Conjugated Estrogens interactionCertified Organic Marshmallow ExtractOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Certified Organic Marshmallow Extract + Bazedoxifene Acetate, Conjugated Estrogens interactionBeclometasone DipropionateBecotide
How Beclometasone Dipropionate interacts with Bladder Support — through 3 ingredients. Tap an ingredient for the detail:
Certified Organic Uva Ursi ExtractCytochrome P450 3a4 (cyp3a4) Substrates, P-glycoprotein Substrates Moderate
Interaction Summary
Theoretically, uva ursi may decrease the metabolism of CYP3A4 substrates.
Read the full Certified Organic Uva Ursi Extract + Beclometasone Dipropionate interactionCertified Organic Cornsilk ExtractCorticosteroids Moderate
Interaction Summary
Taking corn silk with corticosteroids might increase the risk of hypokalemia.
Read the full Certified Organic Cornsilk Extract + Beclometasone Dipropionate interactionCertified Organic Marshmallow ExtractOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Certified Organic Marshmallow Extract + Beclometasone Dipropionate interactionBeclomethasoneBeclovent, Vanceril
How Beclomethasone interacts with Bladder Support — through 3 ingredients. Tap an ingredient for the detail:
Certified Organic Cornsilk ExtractCorticosteroids Moderate
Interaction Summary
Taking corn silk with corticosteroids might increase the risk of hypokalemia.
Read the full Certified Organic Cornsilk Extract + Beclomethasone interactionCertified Organic Uva Ursi ExtractP-glycoprotein Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, uva ursi may alter the levels of drugs transported by P-glycoprotein.
Read the full Certified Organic Uva Ursi Extract + Beclomethasone interactionCertified Organic Marshmallow ExtractOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Certified Organic Marshmallow Extract + Beclomethasone interactionBeclomethasone DipropionateQNASL, Qvar
How Beclomethasone Dipropionate interacts with Bladder Support — through 3 ingredients. Tap an ingredient for the detail:
Certified Organic Uva Ursi ExtractCytochrome P450 3a4 (cyp3a4) Substrates, P-glycoprotein Substrates Moderate
Interaction Summary
Theoretically, uva ursi may decrease the metabolism of CYP3A4 substrates.
Read the full Certified Organic Uva Ursi Extract + Beclomethasone Dipropionate interactionCertified Organic Cornsilk ExtractCorticosteroids Moderate
Interaction Summary
Taking corn silk with corticosteroids might increase the risk of hypokalemia.
Read the full Certified Organic Cornsilk Extract + Beclomethasone Dipropionate interactionCertified Organic Marshmallow ExtractOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Certified Organic Marshmallow Extract + Beclomethasone Dipropionate interactionBedaquilineSirturo
How Bedaquiline interacts with Bladder Support — through 2 ingredients. Tap an ingredient for the detail:
Certified Organic Uva Ursi ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, uva ursi may decrease the metabolism of CYP3A4 substrates.
Read the full Certified Organic Uva Ursi Extract + Bedaquiline interactionCertified Organic Marshmallow ExtractOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Certified Organic Marshmallow Extract + Bedaquiline interactionBelinostatBeleodaq
How Belinostat interacts with Bladder Support — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Uva Ursi ExtractP-glycoprotein Substrates, Glucuronidated Drugs Moderate
Interaction Summary
Theoretically, uva ursi may alter the levels of drugs transported by P-glycoprotein.
Read the full Certified Organic Uva Ursi Extract + Belinostat interactionBelladonna Alkaloids, Chlorpheniramine, Phenylephrine, PhenylpropanolamineRespa ARM
How Belladonna Alkaloids, Chlorpheniramine, Phenylephrine, Phenylpropanolamine interacts with Bladder Support — through 2 ingredients. Tap an ingredient for the detail:
Certified Organic Uva Ursi ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, uva ursi may decrease the metabolism of CYP3A4 substrates.
Read the full Certified Organic Uva Ursi Extract + Belladonna Alkaloids, Chlorpheniramine, Phenylephrine, Phenylpropanolamine interactionCertified Organic Marshmallow ExtractOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Certified Organic Marshmallow Extract + Belladonna Alkaloids, Chlorpheniramine, Phenylephrine, Phenylpropanolamine interactionBelladonna Alkaloids, Ergotamine Tartrate, PhenobarbitalBel Tabs, Bellamine-S, Bellaphen-S, Duragal S, Phenarbal S, Spastrin
How Belladonna Alkaloids, Ergotamine Tartrate, Phenobarbital interacts with Bladder Support — through 2 ingredients. Tap an ingredient for the detail:
Certified Organic Uva Ursi ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, uva ursi may decrease the metabolism of CYP3A4 substrates.
Read the full Certified Organic Uva Ursi Extract + Belladonna Alkaloids, Ergotamine Tartrate, Phenobarbital interactionCertified Organic Marshmallow ExtractOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Certified Organic Marshmallow Extract + Belladonna Alkaloids, Ergotamine Tartrate, Phenobarbital interactionBelladonna, Caffeine, Ergotamine, PentobarbitalMicomp PB
How Belladonna, Caffeine, Ergotamine, Pentobarbital interacts with Bladder Support — through 3 ingredients. Tap an ingredient for the detail:
Certified Organic Couchgrass ExtractCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, wheatgrass might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Certified Organic Couchgrass Extract + Belladonna, Caffeine, Ergotamine, Pentobarbital interactionCertified Organic Uva Ursi ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, uva ursi may decrease the metabolism of CYP3A4 substrates.
Read the full Certified Organic Uva Ursi Extract + Belladonna, Caffeine, Ergotamine, Pentobarbital interactionCertified Organic Marshmallow ExtractOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Certified Organic Marshmallow Extract + Belladonna, Caffeine, Ergotamine, Pentobarbital interactionBelladonna, Ergotamine Tartrate, Phenobarbital
How Belladonna, Ergotamine Tartrate, Phenobarbital interacts with Bladder Support — through 2 ingredients. Tap an ingredient for the detail:
Certified Organic Uva Ursi ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, uva ursi may decrease the metabolism of CYP3A4 substrates.
Read the full Certified Organic Uva Ursi Extract + Belladonna, Ergotamine Tartrate, Phenobarbital interactionCertified Organic Marshmallow ExtractOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Certified Organic Marshmallow Extract + Belladonna, Ergotamine Tartrate, Phenobarbital interactionBelladonna, Ergotamine, PhenobarbitalBellergal-S
How Belladonna, Ergotamine, Phenobarbital interacts with Bladder Support — through 2 ingredients. Tap an ingredient for the detail:
Certified Organic Uva Ursi ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, uva ursi may decrease the metabolism of CYP3A4 substrates.
Read the full Certified Organic Uva Ursi Extract + Belladonna, Ergotamine, Phenobarbital interactionCertified Organic Marshmallow ExtractOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Certified Organic Marshmallow Extract + Belladonna, Ergotamine, Phenobarbital interactionBellafoline, Caffeine, Ergotamine Tartrate, PentobarbitalCafergot PB
How Bellafoline, Caffeine, Ergotamine Tartrate, Pentobarbital interacts with Bladder Support — through 3 ingredients. Tap an ingredient for the detail:
Certified Organic Couchgrass ExtractCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, wheatgrass might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Certified Organic Couchgrass Extract + Bellafoline, Caffeine, Ergotamine Tartrate, Pentobarbital interactionCertified Organic Uva Ursi ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, uva ursi may decrease the metabolism of CYP3A4 substrates.
Read the full Certified Organic Uva Ursi Extract + Bellafoline, Caffeine, Ergotamine Tartrate, Pentobarbital interactionCertified Organic Marshmallow ExtractOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Certified Organic Marshmallow Extract + Bellafoline, Caffeine, Ergotamine Tartrate, Pentobarbital interactionBelumosudil MesylateRezurock
How Belumosudil Mesylate interacts with Bladder Support — through 2 ingredients. Tap an ingredient for the detail:
Certified Organic Uva Ursi ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, uva ursi may decrease the metabolism of CYP3A4 substrates.
Read the full Certified Organic Uva Ursi Extract + Belumosudil Mesylate interactionCertified Organic Marshmallow ExtractOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Certified Organic Marshmallow Extract + Belumosudil Mesylate interactionBelzutifanWelireg
How Belzutifan interacts with Bladder Support — through 2 ingredients. Tap an ingredient for the detail:
Certified Organic Uva Ursi ExtractCytochrome P450 2c19 (cyp2c19) Substrates, Glucuronidated Drugs Moderate
Interaction Summary
Theoretically, uva ursi may decrease the metabolism of CYP2C19 substrates.
Read the full Certified Organic Uva Ursi Extract + Belzutifan interactionCertified Organic Marshmallow ExtractOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Certified Organic Marshmallow Extract + Belzutifan interactionBenactyzine, MeprobamateDeprol
How Benactyzine, Meprobamate interacts with Bladder Support — through 2 ingredients. Tap an ingredient for the detail:
Certified Organic Uva Ursi ExtractGlucuronidated Drugs Moderate
Interaction Summary
Theoretically, uva ursi may increase levels of drugs metabolized by glucuronidation.
Read the full Certified Organic Uva Ursi Extract + Benactyzine, Meprobamate interactionCertified Organic Marshmallow ExtractOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Certified Organic Marshmallow Extract + Benactyzine, Meprobamate interactionBenazeprilLotensin
How Benazepril interacts with Bladder Support — through 2 ingredients. Tap an ingredient for the detail:
Certified Organic Cornsilk ExtractAntihypertensive Drugs Moderate
Interaction Summary
Taking corn silk extract with antihypertensive drugs might increase the risk of hypotension.
Read the full Certified Organic Cornsilk Extract + Benazepril interactionCertified Organic Marshmallow ExtractOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Certified Organic Marshmallow Extract + Benazepril interactionBenazepril, HydrochlorothiazideLotensin HCT
How Benazepril, Hydrochlorothiazide interacts with Bladder Support — through 2 ingredients. Tap an ingredient for the detail:
Certified Organic Cornsilk ExtractAntihypertensive Drugs, Diuretic Drugs Moderate
Interaction Summary
Taking corn silk extract with antihypertensive drugs might increase the risk of hypotension.
Read the full Certified Organic Cornsilk Extract + Benazepril, Hydrochlorothiazide interactionCertified Organic Marshmallow ExtractOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Certified Organic Marshmallow Extract + Benazepril, Hydrochlorothiazide interactionBendamustineBelrapzo, Treanda, Vivimusta
How Bendamustine interacts with Bladder Support — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Couchgrass ExtractCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, wheatgrass might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Certified Organic Couchgrass Extract + Bendamustine interactionBendamustine HydrochlorideBendeka
How Bendamustine Hydrochloride interacts with Bladder Support — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Couchgrass ExtractCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, wheatgrass might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Certified Organic Couchgrass Extract + Bendamustine Hydrochloride interactionBendroflumethiazideAprinox, Naturetin, Neo-NaClex
How Bendroflumethiazide interacts with Bladder Support — through 2 ingredients. Tap an ingredient for the detail:
Certified Organic Cornsilk ExtractDiuretic Drugs, Antihypertensive Drugs Moderate
Interaction Summary
Taking corn silk with diuretic drugs might increase the risk of adverse effects such as hyponatremia and hypokalemia.
Read the full Certified Organic Cornsilk Extract + Bendroflumethiazide interactionCertified Organic Marshmallow ExtractOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Certified Organic Marshmallow Extract + Bendroflumethiazide interactionBendroflumethiazide, NadololCorzide
How Bendroflumethiazide, Nadolol interacts with Bladder Support — through 2 ingredients. Tap an ingredient for the detail:
Certified Organic Cornsilk ExtractAntihypertensive Drugs, Diuretic Drugs Moderate
Interaction Summary
Taking corn silk extract with antihypertensive drugs might increase the risk of hypotension.
Read the full Certified Organic Cornsilk Extract + Bendroflumethiazide, Nadolol interactionCertified Organic Marshmallow ExtractOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Certified Organic Marshmallow Extract + Bendroflumethiazide, Nadolol interactionBendroflumethiazide, PotassiumCentyl K, Neo-NaClex-K
How Bendroflumethiazide, Potassium interacts with Bladder Support — through 2 ingredients. Tap an ingredient for the detail:
Certified Organic Cornsilk ExtractDiuretic Drugs Moderate
Interaction Summary
Taking corn silk with diuretic drugs might increase the risk of adverse effects such as hyponatremia and hypokalemia.
Read the full Certified Organic Cornsilk Extract + Bendroflumethiazide, Potassium interactionCertified Organic Marshmallow ExtractOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Certified Organic Marshmallow Extract + Bendroflumethiazide, Potassium interactionBendroflumethiazide, Rauwolfia SerpentinaRauzide
How Bendroflumethiazide, Rauwolfia Serpentina interacts with Bladder Support — through 2 ingredients. Tap an ingredient for the detail:
Certified Organic Cornsilk ExtractDiuretic Drugs, Antihypertensive Drugs Moderate
Interaction Summary
Taking corn silk with diuretic drugs might increase the risk of adverse effects such as hyponatremia and hypokalemia.
Read the full Certified Organic Cornsilk Extract + Bendroflumethiazide, Rauwolfia Serpentina interactionCertified Organic Marshmallow ExtractOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Certified Organic Marshmallow Extract + Bendroflumethiazide, Rauwolfia Serpentina interactionBenzhydrocodone, AcetaminophenApadaz
How Benzhydrocodone, Acetaminophen interacts with Bladder Support — through 3 ingredients. Tap an ingredient for the detail:
Certified Organic Couchgrass ExtractCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, wheatgrass might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Certified Organic Couchgrass Extract + Benzhydrocodone, Acetaminophen interactionCertified Organic Uva Ursi ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Glucuronidated Drugs Moderate
Interaction Summary
Theoretically, uva ursi may decrease the metabolism of CYP3A4 substrates.
Read the full Certified Organic Uva Ursi Extract + Benzhydrocodone, Acetaminophen interactionCertified Organic Marshmallow ExtractOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Certified Organic Marshmallow Extract + Benzhydrocodone, Acetaminophen interactionBenzthiazideExna
How Benzthiazide interacts with Bladder Support — through 2 ingredients. Tap an ingredient for the detail:
Certified Organic Cornsilk ExtractAntihypertensive Drugs, Diuretic Drugs Moderate
Interaction Summary
Taking corn silk extract with antihypertensive drugs might increase the risk of hypotension.
Read the full Certified Organic Cornsilk Extract + Benzthiazide interactionCertified Organic Marshmallow ExtractOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Certified Organic Marshmallow Extract + Benzthiazide interactionBepridilVascor
How Bepridil interacts with Bladder Support — through 2 ingredients. Tap an ingredient for the detail:
Certified Organic Uva Ursi ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, uva ursi may decrease the metabolism of CYP3A4 substrates.
Read the full Certified Organic Uva Ursi Extract + Bepridil interactionCertified Organic Marshmallow ExtractOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Certified Organic Marshmallow Extract + Bepridil interactionBetamethasoneCelestone, Diprolene AF, Diprosone
How Betamethasone interacts with Bladder Support — through 3 ingredients. Tap an ingredient for the detail:
Certified Organic Cornsilk ExtractCorticosteroids Moderate
Interaction Summary
Taking corn silk with corticosteroids might increase the risk of hypokalemia.
Read the full Certified Organic Cornsilk Extract + Betamethasone interactionCertified Organic Marshmallow ExtractOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Certified Organic Marshmallow Extract + Betamethasone interactionCertified Organic Uva Ursi ExtractP-glycoprotein Substrates Minor
Interaction Summary
Theoretically, uva ursi may alter the levels of drugs transported by P-glycoprotein.
Read the full Certified Organic Uva Ursi Extract + Betamethasone interactionBetamethasone DipropionateSernivo
How Betamethasone Dipropionate interacts with Bladder Support — through 2 ingredients. Tap an ingredient for the detail:
Certified Organic Cornsilk ExtractCorticosteroids Moderate
Interaction Summary
Taking corn silk with corticosteroids might increase the risk of hypokalemia.
Read the full Certified Organic Cornsilk Extract + Betamethasone Dipropionate interactionCertified Organic Uva Ursi ExtractP-glycoprotein Substrates Minor
Interaction Summary
Theoretically, uva ursi may alter the levels of drugs transported by P-glycoprotein.
Read the full Certified Organic Uva Ursi Extract + Betamethasone Dipropionate interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Bladder Support with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
certified organic Marshmallow extract
Lithium
Theoretically, due to potential diuretic effects, marshmallow might reduce excretion and increase levels of lithium.
Marshmallow is thought to have diuretic properties. To avoid lithium toxicity, the dose of lithium might need to be decreased when used with marshmallow.
Anticoagulant/Antiplatelet Drugs
Theoretically, marshmallow flower might have antiplatelet effects.
Animal research suggests that marshmallow flower extract has antiplatelet effects. However, the root and leaf of marshmallow, not the flower, are the plant parts most commonly found in dietary supplements. Theoretically, use of marshmallow flower with anticoagulant/antiplatelet drugs can have additive effects, and might increase the risk for bleeding in some patients.
Oral Drugs
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Marshmallow contains mucilage which can affect oral drug absorption. To avoid changes in absorption, take marshmallow 30-60 minutes after oral medications.
certified organic Uva Ursi extract
Cytochrome P450 2C19 (Cyp2C19) Substrates
Theoretically, uva ursi may decrease the metabolism of CYP2C19 substrates.
In vitro, uva ursi appears to inhibit cytochrome CYP2C19. This effect has not been reported in humans.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, uva ursi may decrease the metabolism of CYP3A4 substrates.
In vitro, uva ursi appears to inhibit CYP3A4. This effect has not been reported in humans.
Glucuronidated Drugs
Theoretically, uva ursi may increase levels of drugs metabolized by glucuronidation.
In vitro, uva ursi extract appears to strongly inhibit UDP-glucuronosyltransferase (UGT) 1A1 (UGT1A1). However, uva ursi extract does not appear to inhibit UGT1A1 in animal models. This effect has not been reported in humans.
Lithium
Theoretically, uva ursi may increase lithium levels, necessitating a decrease in dose.
Uva ursi may have diuretic properties. Diuretics may increase lithium reabsorption with sodium in the proximal tubule of the kidney. Theoretically, uva ursi might reduce excretion and increase levels of lithium.
Urinary Acidifying Agents
Effects of uva ursi in the urinary tract may be reduced by urinary acidifying agents.
Uva ursi seems to work best in alkaline urine. Theoretically, taking uva ursi with medications known to acidify the urine may decrease any effects of uva ursi on the urinary tract.
P-Glycoprotein Substrates
Theoretically, uva ursi may alter the levels of drugs transported by P-glycoprotein.
In vitro, uva ursi appears to inhibit the multi-drug transporter protein, P-glycoprotein. This effect has not been reported in humans.
certified organic Cornsilk extract
Antidiabetes Drugs
Theoretically, taking corn silk with antidiabetes drugs might increase the risk of hypoglycemia.
Animal research in diabetic mice shows that taking corn silk extract lowers fasting blood glucose levels.
Antihypertensive Drugs
Taking corn silk extract with antihypertensive drugs might increase the risk of hypotension.
Clinical research in both hypertensive and normotensive adults shows that taking corn silk extract lowers systolic and diastolic blood pressure.
Corticosteroids
Taking corn silk with corticosteroids might increase the risk of hypokalemia.
Clinical research shows that taking corn silk extract increases the urinary excretion of potassium.
Diuretic Drugs
Taking corn silk with diuretic drugs might increase the risk of adverse effects such as hyponatremia and hypokalemia.
Clinical research shows that taking corn silk extract increases urine volume and promotes the urinary excretion of sodium and potassium. Some patients may require electrolyte supplementation.
Warfarin (Coumadin)
Theoretically, suddenly stopping, starting, or changing corn silk treatment may alter the effects of warfarin.
Corn silk contains vitamin K. Individuals taking warfarin should consume a consistent daily amount of corn silk to maintain consistent anticoagulation.
certified organic Couchgrass extract
Antidiabetes Drugs
Theoretically, taking wheatgrass with antidiabetes drugs might lower blood glucose levels and increase the risk of hypoglycemia.
Animal research shows that taking wheatgrass stimulates the release of insulin from beta-cells and lowers blood glucose.
Cytochrome P450 1A2 (Cyp1A2) Substrates
Theoretically, wheatgrass might decrease the levels and clinical effects of CYP1A2 substrates.
In vitro research shows that wheatgrass induces CYP1A2 enzymes.
certified organic Yarrow extract
Lithium
Theoretically, taking yarrow with lithium might increase the levels and adverse effects of lithium.
Animal research shows that yarrow has diuretic activity. Theoretically, due to these potential diuretic effects, yarrow might reduce excretion and increase levels of lithium. The dose of lithium might need to be decreased.
Brand information
Manufacturer and brand details for Bladder Support, from the product label.
Bladder Support by Herbal Terra: Common Questions
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Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Bladder Support is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Bladder Support’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Corn Silk
Interacts with 290 drugsCorn silk is a traditional herbal remedy taken as a tea or extract, mostly for urinary and mild fluid-related complaints. High-quality human evidence for these uses is limited, so it should...
Read the full Corn Silk monograph → Herb & supplement monographWheatgrass
Interacts with 272 drugsWheatgrass is the young grass of the wheat plant, taken as a juice or powder, and is mainly used as a concentrated source of vitamins and plant nutrients. Solid scientific evidence for most...
Read the full Wheatgrass monograph → Herb & supplement monographMarshmallow
Interacts with 2,040 drugsMarshmallow root is a traditional herb rich in soothing, gel-like fibers called mucilage, which is why it has long been used for coughs, sore throats, and stomach irritation. Evidence for th...
Read the full Marshmallow monograph → Herb & supplement monographUva Ursi
Interacts with 803 drugsUva ursi is a traditional herb used mainly for urinary tract infections, and its leaves contain a compound called arbutin that may have antimicrobial effects in the urine. Evidence in people...
Read the full Uva Ursi monograph → Herb & supplement monographYarrow
Interacts with 1 drugYarrow is a traditional herb long used for wounds, digestive complaints, and colds, but high-quality human studies are very limited, so its benefits are not well proven. It is generally used...
Read the full Yarrow monograph →Sources & How We Checked
Bladder Support's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 30 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Corn Silk 4 references
- Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
- Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
- George GO, Idu FK. Corn silk aqueous extracts and intraocular pressure of systemic and non-systemic hypertensive subjects. Clin Exp Optom. 2015 Mar;98(2):138-49. PubMed
- Sheng L, Chen Q, Di L, Li N. Evaluation of anti-diabetic potential of corn silk in high-fat diet/streptozotocin- induced type 2 diabetes mice model. Endocr Metab Immune Disord Drug Targets. 2020. PubMed
Wheatgrass 5 references
- Ben-Arye E, Golden E, Wengrower D, et al. Wheat grass juice in the treatment of active distal ulcerative colitis a randomized double-blind placebo-controlled trial. Scand J Gastroenterol 2002;4:444-9.. PubMed
- Mohan Y, Jesuthankaraj GN1, Ramasamy Thangavelu N. Antidiabetic and antioxidant properties of Triticum aestivum in streptozotocin-induced diabetic rats. Adv Pharmacol Sci 2013;2013:716073.
- Shakya G, Randhi PK, Pajaniradje S, Mohankumar K, Rajagopalan R. Hypoglycaemic role of wheatgrass and its effect on carbohydrate metabolic enzymes in type II diabetic rats. Toxicol Ind Health 2016;32(6):1026-32. PubMed
- Food and Drug Administration. Food Allergen Labeling and Consumer Protection Act of 2004 (FALCPA); Public Law 108-282, Title II. Accessed on May 19, 2021. Available at: https://www.fda.gov/food/food-allergensgluten-free-guidance-documents-regulatory-infor
- Haron MH, Dale O, Martin K, et al. Evaluation of the Herb-Drug Interaction Potential of Commonly Used Botanicals on the US Market with Regard to PXR- and AhR-Mediated Influences on CYP3A4 and CYP1A2. J Diet Suppl 2022. PubMed
Marshmallow 5 references
- Monographs on the medicinal uses of plant drugs. Exeter, UK: European Scientific Co-op Phytother, 1997.
- Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics. 2nd ed. New York, NY: John Wiley & Sons, 1996.
- McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
- Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
- Hage-Sleiman R, Mroueh M, Daher CF. Pharmacological evaluation of aqueous extract of Althaea officinalis flower grown in Lebanon. Pharm Biol 2011;49(3):327-33.
Uva Ursi 8 references
- Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
- Schulz V, Hansel R, Tyler VE. Rational Phytotherapy: A Physician's Guide to Herbal Medicine. Terry C. Telger, transl. 3rd ed. Berlin, GER: Springer, 1998.
- Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
- Wang L, Del Priore LV. Bull's-eye maculopathy secondary to herbal toxicity from uva ursi. Am J Ophthalmol 2004;137:1135-7. PubMed
- Beaux, D., Fleurentin, J., and Mortier, F. Effect of extracts of Orthosiphon stamineus Benth, Hieracium pilosella L., Sambucus nigra L. and Arctostaphylos uva-ursi (L.) Spreng. in rats. Phytother.Res 1999;13(3):222-225.
- de Arriba SG, Naser B, Nolte KU. Risk assessment of free hydroquinone derived from Arctostaphylos Uva-ursi folium herbal preparations. Int J Toxicol. 2013;32(6):442-453.
- Park JB, Kim D, Min JS, et al. Identification and characterization of in vitro inhibitors against UDP-glucuronosyltransferase 1A1 in uva-ursi extracts and evaluation of in vivo uva-ursi-drug interactions. Food Chem Toxicol. 2018;120:651-661. PubMed
- Chauhan B, Yu C, Krantis A, et al. In vitro activity of uva-ursi against cytochrome P450 isoenzymes and P-glycoprotein. Can J Physiol Pharmacol. 2007;85(11):1099-107.
Yarrow 8 references
- McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
- Uter, W., Nohle, M., Randerath, B., and Schwanitz, H. J. Occupational contact urticaria and late-phase bronchial asthma caused by compositae pollen in a florist. Am J Contact Dermat. 2001;12(3):182-184. DOI
- Schempp, C. M., Schopf, E., and Simon, J. C. [Plant-induced toxic and allergic dermatitis (phytodermatitis)]. Hautarzt 2002;53(2):93-97.
- Jovanovic, M., Poljacki, M., Duran, V., Vujanovic, L., Sente, R., and Stojanovic, S. Contact allergy to Compositae plants in patients with atopic dermatitis. Med Pregl. 2004;57(5-6):209-218. PubMed
- Becker LC, Bergfeld WF, Belsito DV, et al. Safety assessment of Achillea millefolium as used in cosmetics. Int J Toxicol. 2016;35(3 suppl):5S-15S.
- Zakeri S, Esmaeilzadeh S, Gorji N, Memariani Z, Moeini R, Bijani A. The effect of Achillea millefolium L. on vulvovaginal candidiasis compared with clotrimazole: A randomized controlled trial. Complement Ther Med. 2020;52:102483. PubMed
- de Souza P, Crestani S, da Silva Rde C, et al. Involvement of bradykinin and prostaglandins in the diuretic effects of Achillea millefolium L. (Asteraceae). J Ethnopharmacol. 2013 Aug 26;149(1):157-61. PubMed
- Miranzadeh S, Adib-Hajbaghery M, Soleymanpoor L, Ehsani M. Effect of adding the herb Achillea millefolium on mouthwash on chemotherapy induced oral mucositis in cancer patients: A double-blind randomized controlled trial. Eur J Oncol Nurs. 2015;19(3):207- PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC