Interactions on record — worth a quick check against your medications. Check your meds →
Dietary supplement

Blood Sugar Support Formula Ingredients & Drug Interactions

by Carotec

Blood Sugar Support Formula label
See full label image
Capsule Category: Botanical With Nutrients
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Blood Sugar Support Formula against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Blood Sugar Support Formula is a dietary supplement by Carotec with 2 active ingredients. Its ingredients are commonly taken for blood sugar support in type 2 diabetes, weight loss and appetite control, insulin sensitivity.Based on those ingredients, 468 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are ABALife, Chromium. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Blood Sugar Support Formula by Carotec

Ask about any prescription or over-the-counter medication and we check it for interactions with Blood Sugar Support Formula by Carotec — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
Prefer a human? Send your question to our licensed pharmacists — free, answered by email within 24 hours.

HelloPharmacist Scorecard of Blood Sugar Support Formula by Carotec

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

This formula has two active ingredients. Chromium is a mineral that plays a role in how your body uses glucose and insulin.

ABALife is a fig leaf extract—the product uses fig leaf rather than fig fruit, which is a less-studied form. The capsules also contain microcrystalline cellulose (a filler), Nu-Flow (a flow agent to keep powder from clumping), and vegetable-based capsule material.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: Blood sugar support.
  • We looked for evidence on: Antiretroviral-induced insulin resistance, Chromium deficiency, Diabetes, Hyperlipidemia, Hypoglycemia, Impaired glucose tolerance (Prediabetes) — and 4 related terms.
  • The strongest evidence on file: Chromium is rated "Likely Effective" for Chromium deficiency (Natural Medicines).
  • Also on file: Chromium is rated "Possibly Effective" for Diabetes.
  • Also on file: Chromium is rated "Possibly Ineffective" for Impaired glucose tolerance (Prediabetes).

Chromium is rated Likely Effective for chromium deficiency and Possibly Effective for diabetes, meaning there's some research backing its use for blood sugar control. For prediabetes, the evidence rates as Possibly Ineffective.

Chromium does not appear effective for schizophrenia or high blood pressure. Fig leaf's effectiveness is less clear—the evidence we hold rates it as Insufficient Reliable Evidence to rate for constipation, diabetes, eczema, melasma, and vitiligo.

So while there's a small clinical study showing fig leaf may lower blood sugar in type 1 diabetes, the overall body of evidence is too limited to say how well it works.

The evidence, ingredient by ingredient Chromium Fig

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Chromium is generally well tolerated at typical supplement doses, though high or long-term doses may carry risks. The most common side effects are gastrointestinal irritation, headaches, insomnia, irritability, and mood changes.

Rare serious effects include kidney and liver damage and blood cell problems; one case of anemia and blood cell counts dropping was reported in a patient taking very high doses (1,200–2,400 mcg daily) for several months. Chromium can also trigger skin rashes, hives, or contact dermatitis in people sensitive to chromium.

Fig fruit as food is safe for most people, but this product uses a concentrated leaf extract, which has less safety data. Fig leaf can cause photodermatitis (a severe sun-triggered skin reaction), and rare cases of allergic reactions including anaphylaxis have been reported with fig.

Pregnancy and lactation data for this ingredient show it is Likely Safe. No pregnancy or lactation data are on file for chromium; the safety notes advise against extra chromium supplement doses during pregnancy and breastfeeding unless a doctor recommends it.

Side effects, ingredient by ingredient Chromium Fig

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 2 of the 2 matched ingredients can interact with medications — Fig, Chromium.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 468 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check before taking this product if you're on insulin or antidiabetes drugs (both ingredients may lower blood sugar too much), levothyroxine or other thyroid hormone (chromium may reduce absorption), or photosensitizing drugs like fluoroquinolone antibiotics, tetracycline antibiotics, sulfa antibiotics, or certain antidepressants (fig leaf may increase sun sensitivity). NSAIDs and aspirin may increase chromium retention, so mention those too.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with clinical evidence supporting its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This product is designed for people managing blood sugar, but it's not a substitute for diabetes medication. If you take insulin, diabetes pills, or thyroid hormone, you need to check with your pharmacist before starting—the interactions are real and could affect how your drugs work.

If you're on a photosensitizing medication, talk to us first because the fig leaf component can increase sun sensitivity. Otherwise, it's generally well tolerated at normal doses.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jan 23, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Blood Sugar Support Formula, straight from the product label.

Brand Carotec
Net contents 60 Capsule(s)
Market status On market
Date entered into DSLD Jan 23, 2023
DSLD ID 282123
Product type Botanical With Nutrients
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Blood Sugar Support Formula by Carotec, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
30
IngredientAmount% DV
Chromium200 mcg571%
ABALife200 mg--

Other ingredients: Microcrystalline Cellulose, Nu-Flow, Vegetable Capsules

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested Use: Take two (2) capsules per day, with meals, or as recommended by your health care practitioner.

Precautions

Warning: Do not exceed recommended dose.

Pregnant or nursing mothers, children under 18, and individuals with a known medical condition should consult a physician before using this or any dietary supplement.

Pregnant or nursing mothers, children under 18, and individuals with a known medical condition should consult a physician before using this or any dietary supplement. Keep out of reach of children.

Do not use if safety seal is damaged or missing.

Storage

Store in a cool, dry place.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

FDA Statement of Identity

Dietary Supplement

Formula

ABALife

Brand IP Statement(s)

ABALife is a trademark of EUROMED USA, Inc.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Blood Sugar Support Formula by Carotec label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Blood Sugar Support Formula label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Blood Sugar Support Formula by Carotec

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Chromium

Interacts with
178 drugs
200 mcg per serving Form: Chromium Nicotinate Glycinate Chelate

Chromium is an essential trace mineral involved in how the body handles sugar and fat. Some studies suggest it may modestly help blood sugar control i...

Chromium monograph & interactions

ABALife

Interacts with
410 drugs
200 mg per serving Form: Fig fruit extract

Fig (Ficus carica) is a common fruit that has long been used as a gentle food remedy for constipation, and its leaves are used traditionally for blood...

ABALife monograph & interactions

Other (inactive) ingredients: Microcrystalline Cellulose, Nu-Flow, Vegetable Capsules. These complete the product’s ingredient list but are not active constituents.

Interaction report

Blood Sugar Support Formula by Carotec Drug Interactions

Want to check YOUR meds against Blood Sugar Support Formula?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
468Drugs
413 Moderate 55 Minor

Ingredients driving the most interactions

ABALife 410
Chromium 178

Individual Drug Interactions

The ingredients in Blood Sugar Support Formula interact with 468 drugs. Click any drug to see the details.

2 of the 2 ingredients in Blood Sugar Support Formula interact with drugs. Each result below shows which ingredient is responsible. ABALife Chromium

Each ingredient & the kinds of drugs it affects

For each ingredient in Blood Sugar Support Formula with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

ABALife3 drug types · 410 drugs

Antidiabetes Drugs

Theoretically, fig leaf might enhance the blood glucose lowering effects of hypoglycemic drugs.
A small clinical study in patients with type 1 diabetes shows that consuming a tea made from fig leaves modestly reduces postprandial glucose levels and insulin requirements.

Likelihood Probable Evidence B
Insulin

Fig leaf may enhance the blood glucose lowering effects of insulin.
A small clinical study in patients with type 1 diabetes shows that consuming a tea made from fig leaves modestly reduces postprandial glucose levels and insulin requirements.

Likelihood Probable Evidence B
Photosensitizing Drugs

Theoretically, fig might increase the risk of photosensitivity when used in combination with photosensitizing drugs.
Many cases of photodermatitis from fig leaf have been reported. Some drugs that also cause photosensitivity include amitriptyline (Elavil), quinolones (Ciprofloxacin, others), sulfa drugs (Septra, Bactrim, others), and tetracycline.

Likelihood Possible Evidence D
ABALife full monograph & interactions

Chromium5 drug types · 178 drugs

Antidiabetes Drugs

Theoretically, chromium may have additive effects with antidiabetic agents and increase the risk of hypoglycemia.
Some research shows that taking chromium might lower blood glucose levels, especially in patients with poorly controlled type 2 diabetes.

Likelihood Possible Evidence A
Insulin

Theoretically, concomitant use of chromium and insulin might increase the risk of hypoglycemia.
In clinical research, chromium has been shown to increase insulin sensitivity,

Likelihood Possible Evidence B
Levothyroxine (Synthroid, Others)

Chromium might bind levothyroxine in the intestinal tract and decrease levothyroxine absorption.
Clinical research in healthy volunteers shows that taking chromium picolinate 1000 mcg with levothyroxine 1 mg decreases serum levels of levothyroxine by 17% when compared to taking levothyroxine alone. Advise patients to take levothyroxine at least 30 minutes before or 3-4 hours after taking chromium.

Likelihood Probable Evidence B
Aspirin

Theoretically, aspirin might increase chromium absorption.
Animal research suggests that aspirin may increase chromium absorption and chromium levels in the blood.

Likelihood Possible Evidence D
Nonsteroidal Anti-Inflammatory Drugs (Nsaids)

NSAIDs might increase chromium levels in the body.
Drugs that are prostaglandin inhibitors, such as NSAIDs, seem to increase chromium absorption and retention.

Likelihood Possible Evidence D
Chromium full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Blood Sugar Support Formula, from the product label.

Carotec

See all Carotec products
Name
Carotec, Inc.
Street Address
P.O. Box 9919
City
Naples
State
FL
ZipCode
34101
Phone Number
1-800-522-4279
Web Address
www.carotec.com
Pharmacist Counseling Corner

Blood Sugar Support Formula by Carotec: Common Questions

Does Blood Sugar Support Formula by Carotec interact with any medications?
Yes. Based on its ingredients, Blood Sugar Support Formula has a known interaction with 468 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Blood Sugar Support Formula contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm on metformin or another diabetes medication?
No, not without checking with your pharmacist first. Both chromium and fig leaf in this formula can add to the blood-sugar-lowering effects of diabetes drugs, raising the risk of low blood sugar (hypoglycemia). Your doctor or pharmacist needs to know you're taking this so they can monitor you and adjust your diabetes medication if needed.
Will this affect my thyroid medication?
Yes, possibly. Chromium may bind to levothyroxine (Synthroid) in your gut and reduce how much your body absorbs—studies show about a 17% drop in levothyroxine levels. Take your thyroid medication at least 2 hours apart from this product, and have your thyroid levels rechecked a few weeks after starting or stopping it.
What are the most common side effects?
With chromium, you might experience gastrointestinal irritation, headaches, insomnia, irritability, or mood changes. The fig leaf component can cause skin rashes or hives, and in rare cases, allergic reactions. Stop and contact your doctor if you develop a rash, especially after sun exposure, or have trouble breathing.
Is this safe to use while pregnant or breastfeeding?
Fig leaf is rated Likely Safe in pregnancy and lactation. Chromium, though, has limited safety data at higher supplement doses—small amounts from food or prenatal vitamins are fine, but the extra chromium in this product should be avoided unless your doctor specifically recommends it. Talk with your doctor before taking this during pregnancy or while breastfeeding.
What's the difference between the fig in this product and the fig I eat?
This product uses a concentrated fig leaf extract, not fig fruit. Fig fruit (the one you eat) is a safe food. The leaf extract is less studied for safety, especially in higher medicinal doses, so it carries more caution. Also, fig leaf can cause photodermatitis—a severe sun-triggered skin reaction—particularly if you're on certain antibiotics or other photosensitizing drugs.
Does chromium really help with blood sugar?
Chromium is Likely Effective for chromium deficiency and Possibly Effective for diabetes—meaning there's some research behind it, especially for people with poorly controlled type 2 diabetes. For prediabetes, though, the evidence rates as Possibly Ineffective. It's not a replacement for medication or lifestyle changes, but it may play a supporting role if your doctor thinks you need it.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Blood Sugar Support Formula is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Blood Sugar Support Formula label
Go deeper

The Full Monographs Behind Blood Sugar Support Formula’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Chromium

Interacts with 178 drugs

Chromium is an essential trace mineral involved in how the body handles sugar and fat. Some studies suggest it may modestly help blood sugar control in certain people with type 2 diabetes, b...

Read the full Chromium monograph → Herb & supplement monograph

Fig

Interacts with 410 drugs

Fig (Ficus carica) is a common fruit that has long been used as a gentle food remedy for constipation, and its leaves are used traditionally for blood sugar and coughs. The fruit is a safe a...

Read the full Fig monograph →
Sources

Sources & How We Checked

Blood Sugar Support Formula's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 66 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Chromium 53 references
  1. Cerulli J, Grabe DW, Gauthier I, et al. Chromium picolinate toxicity. Ann Pharmacother 1998;32:428-31. PubMed
  2. Urberg M, Zemel MB. Evidence for synergism between chromium and nicotinic acid in the control of glucose tolerance in elderly humans. Metabolism 1987;36:896-9. PubMed
  3. Mohamedshah FY, Moser-Veillon PB, Yamini S, et al. Distribution of a stable isotope of chromium (53Cr) in serum, urine, and breast milk in lactating women. Am J Clin Nutr 1998;67:1250-5. PubMed
  4. Wasser WG, Feldman NS, D'Agati VD. Chronic renal failure after ingestion of over-the-counter chromium picolinate. [letter]. Ann Intern Med 1997;126:410. PubMed
  5. Mertz W. Interaction of chromium with insulin: a progress report. Nutr Rev 1998;56:174-7. PubMed
  6. Anderson RA. Chromium, glucose intolerance and diabetes. J Am Coll Nutr 1998;17:548-55. PubMed
  7. McLeod MN, Gaynes BN, Golden RN. Chromium potentiation of antidepressant pharmacotherapy for dysthymic disorder in 5 patients. J Clin Psych 1999;60:237-40. PubMed
  8. Fowler JF Jr. Systemic contact dermatitis caused by oral chromium picolinate. Cutis 2000;65:116. DOI
  9. Trent LK, Thieding-Cancel D. Effects of chromium picolinate on body composition. J Sports Med Phys Fitness 1995;35:273-80.
  10. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. Washington, DC: National Academy Press, 2002.
  11. Rabinovitz H, Friedensohn A, Leibovitz A, et al. Effect of chromium supplementation on blood glucose and lipid levels in type 2 diabetes mellitus elderly patients. Int J Vitam Nutr Res 2004;74:178-82. PubMed
  12. Lanca S, Alves A, Vieira AI, et al. Chromium-induced toxic hepatitis. Eur J Intern Med 2002;13:518-20. PubMed
  13. Kockler DR, McCarthy MW, Lawson CL. Seizure activity and unresponsiveness after hydroxycut ingestion. Pharmacotherapy 2001;21:647-51.. PubMed
  14. Davidson JR, Abraham K, Connor KM, McLeod MN. Effectiveness of chromium in atypical depression: a placebo-controlled trial. Biol Psychiatry 2003;53:261-4.. PubMed
  15. Food Standards Agency. Medicines and Healthcare products Regulatory Agency (MHRA). Expert Group on Vitamins and Minerals. Available at: http://cot.food.gov.uk/sites/default/files/vitmin2003.pdf.
  16. Mouser JF, Hak EB, Helms RA, et al. Chromium and zinc concentrations in pediatric patients receiving long-term parenteral nutrition. Am J Health Syst Pharm 1999;56:1950-6. PubMed
  17. Stevens T, Qadri A, Zein NN. Two patients with acute liver injury associated with use of the herbal weight-loss supplement hydroxycut. Ann Intern Med 2005;142:477-8. PubMed
  18. Wani S, Weskamp C, Marple J, Spry L. Acute tubular necrosis associated with chromium picolinate-containing dietary supplement. Ann Pharmacother 2006;40:563-6. PubMed
  19. Kleefstra N, Houweling ST, Jansman FG, et al. Chromium treatment has no effect in patients with poorly controlled, insulin-treated type 2 diabetes in an obese Western population: a randomized, double-blind, placebo-controlled trial. Diabetes Care 2006;29: PubMed
  20. Martin J, Wang ZQ, Zhang XH, et al. Chromium picolinate supplementation attenuates body weight gain and increases insulin sensitivity in subjects with type 2 diabetes. Diabetes Care 2006;29:1826-32. PubMed
  21. Singer GM, Geohas J. The effect of chromium picolinate and biotin supplementation on glycemic control in poorly controlled patients with type 2 diabetes mellitus: a placebo-controlled, double-blinded, randomized trial. Diabetes Technol Ther 2006;8:636-43. PubMed
  22. John-Kalarickal J, Pearlman G, Carlson HE. New medications which decrease levothyroxine absorption. Thyroid 2007;17:763-5. PubMed
  23. Yazaki Y, Faridi Z, Ma Y, et al. A pilot study of chromium picolinate for weight loss. J Altern Complement Med 2010;16:291-9. PubMed
  24. Davis ML, Seaborn CD, and Stoecker BJ. Effects of over-the-counter drugs on chromium retention and urinary excretion in rats. Nutrition Research 1995;15(2):201-210.
  25. Young P, Turiansky G, Bonner M, and et al. Acute generalized exanthematous pustulosis induced by chromium picolinate. J.Am Acad.Dermatol. 1999;41(5 Pt 2):820-823. PubMed
  26. Gibb, H. J., Lees, P. S., Pinsky, P. F., and Rooney, B. C. Lung cancer among workers in chromium chemical production. Am J Ind.Med 2000;38(2):115-126. DOI
  27. Gibb, H. J., Lees, P. S., Pinsky, P. F., and Rooney, B. C. Clinical findings of irritation among chromium chemical production workers. Am J Ind.Med 2000;38(2):127-131. PubMed
  28. Pittler, M. H. and Ernst, E. Dietary supplements for body-weight reduction: a systematic review. Am.J.Clin Nutr. 2004;79(4):529-536. PubMed
  29. Pei, D., Hsieh, C. H., Hung, Y. J., Li, J. C., Lee, C. H., and Kuo, S. W. The influence of chromium chloride-containing milk to glycemic control of patients with type 2 diabetes mellitus: a randomized, double-blind, placebo-controlled trial. Metabolism 2 PubMed
  30. Hisatomi, K., Ishii, H., Hashiguchi, K., Seki, M., Ide, M., Sugiyama, K., Ishimoto, H., Nakayama, S., Mukae, H., and Kohno, S. Interstitial pneumonia caused by inhalation of fumes of nickel and chrome. Respirology. 2006;11(6):814-817. PubMed
  31. Kleefstra, N., Houweling, S. T., Bakker, S. J., Verhoeven, S., Gans, R. O., Meyboom-de Jong, B., and Bilo, H. J. Chromium treatment has no effect in patients with type 2 diabetes in a Western population: a randomized, double-blind, placebo-controlled tri DOI
  32. Parsons, A., Ingram, J., Inglis, J., Aveyard, P., Johnstone, E., Brown, K., Franklin, M., and Bermudez, I. A proof of concept randomised placebo controlled factorial trial to examine the efficacy of St John's wort for smoking cessation and chromium to pr
  33. Bagdon RE and Hazen RE. Skin permeation and cutaneous hypersensitivity as a basis for making risk assessments of chromium as a soil contaminant. Environ.Health Perspect. 1991;92:111-119. PubMed
  34. Bharmal, S. V., Moyes, V., Ahmed, S., and Grossman, A. Hypoglycaemia: possible mediation by chromium salt medication. Hormones.(Athens.) 2010;9(2):181-183. PubMed
  35. Krol, E., Krejpcio, Z., Byks, H., Bogdanski, P., and Pupek-Musialik, D. Effects of chromium brewer's yeast supplementation on body mass, blood carbohydrates, and lipids and minerals in type 2 diabetic patients. Biol.Trace Elem.Res. 2011;143(2):726-737.
  36. Unisa, S., Jagannath, P., Dhir, V., Khandelwal, C., Sarangi, L., and Roy, T. K. Population-based study to estimate prevalence and determine risk factors of gallbladder diseases in the rural Gangetic basin of North India. HPB (Oxford) 2011;13(2):117-125. PubMed
  37. Noda, S., Asano, Y., and Sato, S. Lichen planus in a patient with long-term exposure to chrome. Eur.J.Dermatol. 2011;21(3):417-418. PubMed
  38. Xiang, J., Sun, Z., and Huan, J. N. Intensive chromic acid burns and acute chromium poisoning with acute renal failure. Chin Med.J.(Engl.) 7-5-2011;124(13):2071-2073.
  39. Chhabra, D., Oda, K., Jagannath, P., Utsunomiya, H., Takekoshi, S., and Nimura, Y. Chronic heavy metal exposure and gallbladder cancer risk in India, a comparative study with Japan. Asian Pac.J.Cancer Prev. 2012;13(1):187-190. PubMed
  40. Huszonek, J. Over-the-counter chromium picolinate. Am J Psychiatry 1993;150(10):1560-1561. PubMed
  41. Bunner S and McGinnis R. Chromium-induced hypoglycemia. Psychosomatics 1998;39(3):298-299. PubMed
  42. Martin, W. R. and Fuller, R. E. Suspected chromium picolinate-induced rhabdomyolysis. Pharmacotherapy 1998;18(4):860-862. DOI
  43. Proctor, D. M., Fredrick, M. M., Scott, P. K., Paustenbach, D. J., and Finley, B. L. The prevalence of chromium allergy in the United States and its implications for setting soil cleanup: a cost-effectiveness case study. Regul.Toxicol Pharmacol 1998;28(1 PubMed
  44. De Marchi S, Cecchin E, De Marchi SU. Systemic allergic dermatitis resulting from oral administration of chromium with a food supplement. Contact Dermatitis 2014;70(2):123-5. PubMed
  45. Hedberg YS, Gumulka M, Lind ML, Matura M, Lidén C. Severe occupational chromium allergy despite cement legislation. Contact Dermatitis. 2014;70(5):321-3. PubMed
  46. Thyssen JP, Jellesen MS, Møller P, Menné T, Johansen JD. Allergic chromium dermatitis from wearing 'chromium-free' footwear. Contact Dermatitis 2014;70(3):185-7. PubMed
  47. Liu Y, Cotillard A, Vatier C, et al. A Dietary Supplement Containing Cinnamon, Chromium and Carnosine Decreases Fasting Plasma Glucose and Increases Lean Mass in Overweight or Obese Pre-Diabetic Subjects: A Randomized, Placebo-Controlled Trial. PLoS One.
  48. Jamilian M, Asemi Z. Chromium Supplementation and the Effects on Metabolic Status in Women with Polycystic Ovary Syndrome: A Randomized, Double-Blind, Placebo-Controlled Trial. Ann Nutr Metab. 2015;67(1):42-8. PubMed
  49. Guimarães MM, Carvalho AC, Silva MS. Effect of chromium supplementation on the glucose homeostasis and anthropometry of type 2 diabetic patients: Double blind, randomized clinical trial: Chromium, glucose homeostasis and anthropometry. J Trace Elem Med Bi PubMed
  50. Paiva AN, Lima JG, Medeiros AC, et al. Beneficial effects of oral chromium picolinate supplementation on glycemic control in patients with type 2 diabetes: A randomized clinical study. J Trace Elem Med Biol. 2015;32:66-72. PubMed
  51. Yin RV, Phung OJ. Effect of chromium supplementation on glycated hemoglobin and fasting plasma glucose in patients with diabetes mellitus. Nutr J. 2015;14:14. PubMed
  52. Jamilian M, Zadeh Modarres S, Amiri Siavashani M, et al. The influences of chromium supplementation on glycemic control, markers of cardio-metabolic risk, and oxidative stress in infertile polycystic ovary syndrome women candidate for in vitro fertilizati
  53. Alinaghi F, Thyssen JP, Zachariae C, Johansen JD. No immediate effect of regulatory reduction of chromium in leather among adult patients with chromium allergy. Contact Dermatitis 2021;85(5):514-522. PubMed

See these in context on the Chromium monograph →

Fig 13 references
  1. Gandolfo M, Baeza M, De Barrio M, Anaphylaxis after eating figs. Allergy 2001;56:462-3. PubMed
  2. Serraclara A, Hawkins F, Perez C, et al. Hypoglycemic action of an oral fig-leaf decoction in type-I diabetic patients. Diabetes Res Clin Pract 1998;39:19-22. PubMed
  3. Rubnov S, Kashman Y, Rabinowitz R, et al. Suppressors of cancer cell proliferation from fig (Ficus carica) resin: isolation and structure elucidation. J Nat Prod 2001;64:993-6.
  4. Dechamp C, Bessot JC, Pauli G, Deviller P. First report of anaphylactic reaction after fig (Ficus carica) ingestion. Allergy 1995;50:514-6.
  5. Zaynoun ST, Aftimos BG, Abi Ali L, et al. Ficus carica; isolation and quantification of the photoactive components. Contact Dermatitis 1984;11:21-5.
  6. Lembo G, Lo Presti M, Balato N. Phytophotodermatitis due to ficus carica. Photodermatol 1985;2:119-20.
  7. Bollero, D., Stella, M., Rivolin, A., Cassano, P., Risso, D., and Vanzetti, M. Fig leaf tanning lotion and sun-related burns: case reports. Burns 2001;27(7):777-779. PubMed
  8. Ozdamar, E., Ozbek, S., and Akin, S. An unusual cause of burn injury: fig leaf decoction used as a remedy for a dermatitis of unknown etiology. J.Burn Care Rehabil. 2003;24(4):229-233. PubMed
  9. Munteanu, M. Contact dermatitis to the sap of fig-tree. Rev.Med.Chir Soc.Med.Nat.Iasi 1989;93(3):602.
  10. Lembo, G., Lo, Presti M., and Balato, N. Phytophotodermatitis due to ficus carica. Photodermatol. 1985;2(2):119-120.
  11. Micali, G., Nasca, M. R., and Musumeci, M. L. Severe phototoxic reaction secondary to the application of a fig leaves' decoction used as a tanning agent. Contact Dermatitis 1995;33(3):212-213. PubMed
  12. Bonamonte D, Foti C, Lionetti N, Rigano L, Angelini G. Photoallergic contact dermatitis to 8-methoxypsoralen in Ficus carica. Contact Dermatitis. 2010;62(6):343-8.
  13. Pinto AR, Machado Cunha I, Rebelo Gomes E. Fig Tree-Induced Phytophotodermatitis: A Case Report on the Perils of a Hobby. Cureus 2023;15(7):e41888. PubMed

See these in context on the Fig monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring
Supplement interaction checker › Check any supplement or product against your medications Drug–drug interactions › Check two or more of your medications against each other Browse medications A–Z › Every drug we've checked against herbs & supplements NDC & pricing lookup › Find a drug’s NDCs, packaging and costs Ask a pharmacist › Free, personal answer from our licensed team