Major interaction on record — check this product against your medications before combining. Based on 4 of 6 ingredients. Check your meds →
Dietary supplement

Bone Broth Protein Greens Ingredients & Drug Interactions

by Ancient Nutrition

Bone Broth Protein Greens label
See full label image
Powder Category: Other Combinations
Most serious interaction: Major
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Bone Broth Protein Greens against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Major

Bone Broth Protein Greens is a dietary supplement by Ancient Nutrition with 6 active ingredients. Its ingredients are commonly taken for preventing or treating low potassium (hypokalemia), supporting healthy blood pressure, muscle cramps.Based on those ingredients, 686 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are organic Alfalfa, Calcium, organic Oat. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Bone Broth Protein Greens by Ancient Nutrition

Ask about any prescription or over-the-counter medication and we check it for interactions with Bone Broth Protein Greens by Ancient Nutrition — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Bone Broth Protein Greens by Ancient Nutrition

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 16, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 2 of its 5 active ingredients.
  • “Bone Broth Protein Greens Blend” is a proprietary blend — the label gives one combined amount (24 Gram(s)) without saying how much of each component you get.

Bone Broth Protein Greens contains 5 active ingredients. The product includes potassium and calcium as mineral supplements, a proprietary blend called Bone Broth Protein Greens Blend that houses beef bone broth protein concentrate, and two plant-based ingredients—organic alfalfa and organic oat.

The product also contains natural pineapple flavor and stevia extract as inactive ingredients to provide taste and sweetness without adding sugar.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

We hold no graded evidence for this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: nutritional protein supplement.
  • Our graded evidence for these ingredients doesn't cover that particular purpose.

The evidence for this product's effectiveness is mixed. Calcium is effective for kidney failure, indigestion, low blood calcium (hypocalcemia), and high blood potassium (hyperkalemia), and likely effective for osteoporosis.

Oats are likely effective for high cholesterol (dyslipidemia) and heart disease prevention. However, alfalfa's effectiveness is not well established—we hold insufficient reliable evidence for its use in diabetes, indigestion, or high cholesterol.

The effectiveness of potassium and beef bone broth protein concentrate is not rated in our data.

The evidence, ingredient by ingredient Potassium Calcium Alfalfa Oats

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 4 of the 4 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 4 of 4.
  • General safety write-ups exist for 4 of 4.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Calcium and oats are generally well-tolerated at recommended doses. The most common oral side effects of calcium are belching, constipation, diarrhea, and stomach upset; rare serious concerns include kidney stones and calciphylaxis.

Oats commonly cause bloating, flatulence, and abdominal distension, especially when you first start—these usually fade as your body adjusts. Potassium is generally well-tolerated when taken as food, but supplements can be risky: common side effects include abdominal pain, nausea, diarrhea, and vomiting; serious but rare effects from high levels include irregular heartbeat, low blood pressure, and confusion.

Alfalfa can cause abdominal discomfort, diarrhea, and gas; rarely, chronic use has been linked to a lupus-like condition. For pregnancy: potassium from food is fine, but supplements require medical guidance; calcium is likely safe within recommended amounts; alfalfa in supplement doses should be avoided because it has estrogen-like activity; oats as food are safe, though concentrated supplements are less studied.

For breastfeeding: potassium supplements should be cleared with your doctor first; calcium is safe at recommended amounts; alfalfa supplement doses should be avoided due to insufficient safety data; oats as food are safe, though supplement forms are less studied.

Side effects, ingredient by ingredient Potassium Calcium Alfalfa Oats

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 4 of the 4 matched ingredients can interact with medications — Alfalfa, Calcium, Oats, Potassium.
  • The most serious interaction on file is rated Major.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; immunosuppressants / transplant drugs; diabetes medications; heart-rhythm medications; lithium.
  • For scale: 686 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, double-check these medication types with your doctor or pharmacist: HIV integrase inhibitors (dolutegravir, elvitegravir—Major severity), blood thinners like warfarin (warfarin—Major), intravenous ceftriaxone (Major), blood pressure medications including ACE inhibitors, ARBs, and potassium-sparing diuretics (Moderate), thyroid medication levothyroxine (Moderate), diabetes medications and insulin (Moderate), photosensitizing drugs, birth control pills, hormone therapy, immunosuppressants, and the heart medications sotalol, diltiazem, and calcipotriene (Moderate).

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no assessable stated purpose. Major medication interactions have been identified, and safety information is well characterized.

This product may be worth considering if you're looking for a bone broth protein powder with added greens and minerals, and you have no concerns with calcium or potassium interactions. However, if you take blood pressure medications, blood thinners, diabetes drugs, thyroid medication, or HIV integrase inhibitors, you need to check with your doctor or pharmacist before starting—the interactions here are real and could affect how well your medications work.

Your healthcare provider can tell you whether this product is right for your situation and how to space doses if needed.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 4 of 5 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Apr 25, 2019.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Bone Broth Protein Greens, straight from the product label.

Brand Ancient Nutrition
Barcode (UPC) 816401020079
Net contents 17.5 oz.; 1.09 lbs; 495 Gram(s)
Market status On market
Date entered into DSLD Apr 25, 2019
DSLD ID 200409
Product type Other Combinations
Supplement form Powder
Dietary claims / uses Nutrient, All Other
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Bone Broth Protein Greens by Ancient Nutrition, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
25 Gram(s)
Maximum serving Sizes:
25 Gram(s)
Servings per container
20
UPC/BARCODE
816401020079
IngredientAmount% DV
Calories90 Calorie(s)--
Total Carbohydrates1 Gram(s)1%
Potassium150 mg3%
Calcium20 mg2%
Protein20 Gram(s)--
Bone Broth Protein Greens Blend24 Gram(s)--
Beef Bone Broth Protein concentrate0 NP--
organic Alfalfa0 NP--
organic Oat0 NP--

Other ingredients: natural Pineapple flavor, Stevia (leaf) extract

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

20g protein

Paleo friendly

Introducing a superfood protein powder with 20g of body-building protein plus the power of organic green juice - all with a naturally earthy taste and only 2g carbs (0 sugar)!

Bone broth protein is free of common allergens and the ideal protein source for those who are sensitive to dairy, grains, eggs, nuts and legumes.

Get the health benefits of today's hottest superfood - bone broth - in a delicious and nourishing protein powder that is smooth to mix and easy to use.

20g protein per serving

Superfood protein powder made from real bone broth

Formulation

0g sugar

Gluten free

Dairy free

Soy free

Introducing a superfood protein powder with 20g of body-building protein plus the power of organic green juice - all with a naturally earthy taste and only 2g carbs (0 sugar)!

It's artisanally produced with no artificial ingredients, colors or preservatives.

Bone broth protein is free of common allergens and the ideal protein source for those who are sensitive to dairy, grains, eggs, nuts and legumes.

No artificial ingredients

Grain free

Nut free

Contains no filler ingredients, artificial flavors, colors, sweeteners or preservatives.

General Statements

Gut friendly

Packaged by weight not volume. Some settling may occur.

Due to seasonality of ingredients, variations in color, taste and aroma may occur.

FDA Statement of Identity

Whole Food Dietary Supplement

Seals/Symbols

Paleo friendly

Suggested/Recommended/Usage/Directions

Suggested Use: Mix one heaping scoop (included) in 12 ounces of water , juice or in a smoothie or protein shake one or more times per day. Great with almond, cashew or coconut milk or added to your favorite recipe.

General

BBPGreen20v40618

Precautions

Caution: As with any dietary supplement, consult your healthcare practitioner before using this product, especially if you are pregnant, nursing, or are otherwise under medical supervision.

Do not use if product has been opened or tampered with in any way.

Keep out of reach of children.

Notice: Use this product as a food supplement only. Do not use for weight reduction.

Storage

Store in a cool, dry place.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Bone Broth Protein Greens by Ancient Nutrition label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Bone Broth Protein Greens label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Bone Broth Protein Greens by Ancient Nutrition

These are the 6 active ingredients this product is made of. Select any to open its full monograph.

Serving size25 Gram(s) Dosage formPowder Servings per container20 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Potassium

Interacts with
62 drugs
150 mg per serving

Potassium is an essential mineral your body needs for nerve signals, muscle function, and a steady heartbeat, and most people get enough from a balanc...

Potassium monograph & interactions

Calcium

Interacts with
168 drugs
20 mg per serving

Calcium is an essential mineral your body needs for strong bones, nerve signaling, and muscle function, and supplements can help fill gaps when diet f...

Calcium monograph & interactions

Protein

20 Gram(s) per serving

Bone Broth Protein Greens Blend

24 Gram(s) per serving

Other (inactive) ingredients: Natural Pineapple flavor, Stevia (leaf) extract. These complete the product’s ingredient list but are not active constituents.

Interaction report

Bone Broth Protein Greens by Ancient Nutrition Drug Interactions

Want to check YOUR meds against Bone Broth Protein Greens?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
686Drugs
9 Major 665 Moderate 12 Minor

Ingredients driving the most interactions

organic Alfalfa 583
Calcium 168
organic Oat 86
Potassium 62

Individual Drug Interactions

The ingredients in Bone Broth Protein Greens interact with 686 drugs. Click any drug to see the details.

4 of the 6 ingredients in Bone Broth Protein Greens interact with drugs. Each result below shows which ingredient is responsible. organic Alfalfa Calcium organic Oat Potassium

Each ingredient & the kinds of drugs it affects

For each ingredient in Bone Broth Protein Greens with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

organic Alfalfa6 drug types · 583 drugs

Warfarin (Coumadin)

Theoretically, alfalfa might reduce the anticoagulant activity of warfarin.
Alfalfa contains a large amount of vitamin K. This could theoretically interfere with the activity of warfarin.

Likelihood Probable Evidence D
Antidiabetes Drugs

Theoretically, alfalfa might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Animal research suggests that alfalfa decreases blood sugar in diabetic mice. Also, in one case report, a diabetic patient experienced hypoglycemia after consuming alfalfa extract. Monitor blood glucose levels closely. Dose adjustments might be necessary.

Likelihood Possible Evidence D
Contraceptive Drugs

Theoretically, alfalfa might interfere with the activity of contraceptive drugs.
Alfalfa contains coumestrol, a phytoestrogen, and isoflavonoids, which have estrogenic effects.

Likelihood Possible Evidence D
Estrogens

Theoretically, alfalfa might interfere with hormone therapy.
Alfalfa contains coumestrol, a phytoestrogen, and isoflavonoids, which have estrogenic effects.

Likelihood Possible Evidence D
Immunosuppressants

Theoretically, alfalfa might decrease the efficacy of immunosuppressive therapy.
In vitro research and human case reports suggest that alfalfa may have immunostimulant effects.

Likelihood Possible Evidence D
Photosensitizing Drugs

Theoretically, concomitant use of alfalfa with photosensitizing drugs might have additive effects.
Animal research suggests that excessive doses of alfalfa may increase photosensitivity, possibly due to its chlorophyll content. It is unclear if this effect would be clinically relevant in humans.

Likelihood Possible Evidence D
organic Alfalfa full monograph & interactions

Calcium18 drug types · 168 drugs

Ceftriaxone (Rocephin)

Co-administration of intravenous calcium and ceftriaxone can result in precipitation of a ceftriaxone-calcium salt in the lungs and kidneys.
Avoid administering intravenous calcium in any form, such as parenteral nutrition or Lactated Ringers, within 48 hours of intravenous ceftriaxone. Case reports in neonates show that administering intravenous ceftriaxone and calcium can result in precipitation of a ceftriaxone-calcium salt in the lungs and kidneys. In several cases, neonates have died as a result of this interaction. So far there are no reports in adults; however, there is still concern that this interaction might occur in adults.

Likelihood Probable Evidence D
Dolutegravir (Tivicay)

Calcium seems to reduce levels of dolutegravir.
Advise patients to take dolutegravir either 2 hours before or 6 hours after taking calcium supplements. Pharmacokinetic research suggests that taking calcium carbonate 1200 mg concomitantly with dolutegravir 50 mg reduces plasma levels of dolutegravir by almost 40%. Calcium appears to decrease levels of dolutegravir through chelation.

Likelihood Probable Evidence B
Elvitegravir (Vitekta)

Calcium seems to reduce levels of elvitegravir.
Advise patients to take elvitegravir either 2 hours before or 2 hours after taking calcium supplements. Pharmacokinetic research suggests that taking calcium along with elvitegravir can reduce blood levels of elvitegravir through chelation.

Likelihood Probable Evidence B
Aluminum

Calcium citrate might increase aluminum absorption and toxicity. Other types of calcium do not increase aluminum absorption.
Calcium citrate can increase the absorption of aluminum when taken with aluminum hydroxide. The increase in aluminum levels may become toxic, particularly in individuals with kidney disease. However, the effect of calcium citrate on aluminum absorption is due to the citrate anion rather than calcium cation. Calcium acetate does not appear to increase aluminum absorption.

Likelihood Possible Evidence B
Bictegravir/Emtricitabine/Tenofovir Alafenamide (Biktarvy)

Calcium might decrease levels of bictegravir/emtricitabine/tenofovir alafenamide by reducing its absorption when taken in a fasting state.
Advise patients that bictegravir/emtricitabine/tenofovir alafenamide and calcium can be taken together if taken with food. However, if taken on an empty stomach, bictegravir/emtricitabine/tenofovir alafenamide should not be taken with, or 2 hours after, calcium containing products.

Likelihood Probable Evidence D
Bisphosphonates

Calcium reduces the absorption of bisphosphonates.
Advise patients to take bisphosphonates at least 30 minutes before calcium, but preferably at a different time of day. Calcium supplements decrease absorption of bisphosphonates.

Likelihood Probable Evidence C
Calcipotriene (Dovonex)

Taking calcipotriene with calcium might increase the risk for hypercalcemia.
Calcipotriene is a vitamin D analog used topically for psoriasis. It can be absorbed in sufficient amounts to cause systemic effects, including hypercalcemia. Theoretically, combining calcipotriene with calcium supplements might increase the risk of hypercalcemia.

Likelihood Possible Evidence B
Digoxin (Lanoxin)

Using intravenous calcium with digoxin might increase the risk of fatal cardiac arrhythmias.
Hypercalcemia increases the risk of fatal cardiac arrhythmias with digoxin. However, one retrospective analysis of clinical data suggests that intravenous calcium does not increase the risk of dysrhythmias or mortality in patients receiving digoxin.

Likelihood Possible Evidence B
Diltiazem (Cardizem, Others)

Theoretically, calcium may reduce the therapeutic effects of diltiazem.
Hypercalcemia can reduce the effectiveness of verapamil in atrial fibrillation. Theoretically, calcium might increase this risk of hypercalcemia and reduce the effectiveness of diltiazem.

Likelihood Probable Evidence D
Levothyroxine (Synthroid, Others)

Calcium seems to reduce the absorption and effectiveness of levothyroxine.
Advise patients to take levothyroxine and calcium supplements at least 4 hours apart. Calcium reduces levothyroxine absorption, probably by forming insoluble complexes. Calcium carbonate supplements reduce effectiveness of levothyroxine in patients with hypothyroidism.

Likelihood Probable Evidence B
Lithium

Theoretically, concomitant use of calcium and lithium may increase this risk of hypercalcemia.
Clinical research suggests that long-term use of lithium may cause hypercalcemia in 10% to 60% of patients. Theoretically, concomitant use of lithium and calcium supplements may further increase this risk.

Likelihood Possible Evidence B
Quinolone Antibiotics

Calcium seems to reduce the absorption of quinolone antibiotics.
Advise patients to take oral quinolones at least 2 hours before or 4-6 hours after calcium supplements or calcium-fortified foods. Taking calcium at the same time as oral quinolones can reduce quinolone absorption. Calcium binds to quinolones in the gut.

Likelihood Probable Evidence B
Raltegravir (Isentress)

Calcium may reduce levels of raltegravir.
Pharmacokinetic research shows that taking a single dose of calcium carbonate 3000 mg along with raltegravir 400 mg twice daily modestly decreases the mean area under the curve of raltegravir, but the decrease does not necessitate a dose adjustment of raltegravir. However, a case of elevated HIV-1 RNA levels and documented resistance to raltegravir has been reported for a patient taking calcium carbonate 1 gram three times daily plus vitamin D3 (cholecalciferol) 400 IU three times daily in combination with raltegravir 400 mg twice daily for 11 months. It is thought that calcium reduced raltegravir levels by chelation, leading to treatment failure.

Likelihood Possible Evidence B
Sotalol (Betapace)

Calcium seems to reduce the absorption of sotalol.
Advise patients to separate doses by at least 2 hours before or 4-6 hours after calcium. Calcium appears to reduce the absorption of sotalol, probably by forming insoluble complexes.

Likelihood Possible Evidence B
Tetracycline Antibiotics

Calcium seems to reduce the absorption of tetracycline antibiotics.
Advise patients to take oral tetracyclines at least 2 hours before, or 4-6 hours after calcium supplements. Taking calcium at the same time as oral tetracyclines can reduce tetracycline absorption. Calcium binds to tetracyclines in the gut.

Likelihood Probable Evidence C
Thiazide Diuretics

Taking calcium along with thiazides might increase the risk of hypercalcemia and renal failure.
Thiazides reduce calcium excretion by the kidneys. Using thiazides along with moderately large amounts of calcium carbonate increases the risk of milk-alkali syndrome (hypercalcemia, metabolic alkalosis, renal failure). Patients may need to have their serum calcium levels and/or parathyroid function monitored regularly.

Likelihood Probable Evidence C
Verapamil (Calan, Others)

Theoretically, calcium may reduce the therapeutic effects of verapamil.
Hypercalcemia can reduce the effectiveness of verapamil in atrial fibrillation. Theoretically, use of calcium supplements may increase this risk of hypercalcemia and reduce the effectiveness of verapamil.

Likelihood Probable Evidence D
Calcium Channel Blockers

Intravenous calcium may decrease the effects of calcium channel blockers; oral calcium is unlikely to have this effect.
Intravenous calcium is used to decrease the effects of calcium channel blockers in the management of overdose. Intravenous calcium gluconate has been used before intravenous verapamil (Isoptin) to prevent or reduce the hypotensive effects without affecting the antiarrhythmic effects. But there is no evidence that dietary or supplemental calcium when taken orally interacts with calcium channel blockers.

Likelihood Unlikely Evidence D
Calcium full monograph & interactions

organic Oat2 drug types · 86 drugs

Antidiabetes Drugs

Theoretically, oats may have additive effects with antidiabetic agents and might increase the risk of hypoglycemia.
Consuming oats can decrease blood glucose in patients with diabetes. In those who require insulin, taking oats 100 grams daily for 2 days reduces the insulin dose required to achieve metabolic control.

Likelihood Possible Evidence D
Insulin

Concomitant use of oats and insulin might increase the risk of hypoglycemia.
In patients with insulin-dependent type 2 diabetes, taking oats 100 grams daily for 2 days reduces the insulin dose required to achieve metabolic control.

Likelihood Possible Evidence B
organic Oat full monograph & interactions

Potassium3 drug types · 62 drugs

Ace Inhibitors (Aceis)

Using ACEIs with high doses of potassium increases the risk of hyperkalemia.
ACEIs block the actions of the renin-angiotensin-aldosterone system and reduce potassium excretion. Concomitant use of these drugs with potassium supplements increases the risk of hyperkalemia. However, concomitant use of these drugs with moderate dietary potassium intake (about 3775-5200 mg daily) does not increase serum potassium levels.

Likelihood Likely Evidence C
Angiotensin Receptor Blockers (Arbs)

Using ARBs with high doses of potassium increases the risk of hyperkalemia.
ARBs block the actions of the renin-angiotensin-aldosterone system and reduce potassium excretion. Concomitant use of these drugs with potassium supplements increases the risk of hyperkalemia. However, concomitant use of these drugs with moderate dietary potassium intake (about 3775-5200 mg daily) does not increase serum potassium levels.

Likelihood Likely Evidence C
Potassium-Sparing Diuretics

Concomitant use increases the risk of hyperkalemia.
Using potassium-sparing diuretics with potassium supplements increases the risk of hyperkalemia.

Likelihood Likely Evidence C
Potassium full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Bone Broth Protein Greens, from the product label.

Ancient Nutrition

See all Ancient Nutrition products
Name
Ancient Nutrition, LLC
Street Address
2000 Mallory Lane Suite 130-307
City
Franklin
State
TN
ZipCode
37067
Web Address
www.AncientNutrition.com
Pharmacist Counseling Corner

Bone Broth Protein Greens by Ancient Nutrition: Common Questions

Does Bone Broth Protein Greens by Ancient Nutrition interact with any medications?
Yes. Based on its ingredients, Bone Broth Protein Greens has a known interaction with 686 medications, including 9 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Bone Broth Protein Greens contains 6 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does this product have any major medication interactions I should know about?
Yes. The calcium in it can substantially reduce blood levels of two HIV integrase inhibitors (dolutegravir and elvitegravir) and can form dangerous precipitates if combined with intravenous ceftriaxone. The alfalfa can reduce how well warfarin (a blood thinner) works. These are serious, so check with your doctor or pharmacist before using this product if you take any of these medications.
Can I take this if I'm on blood pressure medication?
It depends on which one. If you take an ACE inhibitor, an ARB, or a potassium-sparing diuretic, the potassium in this product could raise your blood potassium to unsafe levels. Talk with your doctor or pharmacist first—they'll know your specific medication and can advise you.
What are the main side effects I might experience?
Calcium commonly causes bloating, constipation, or diarrhea. Oats often trigger flatulence and bloating at first, especially when you start, but these usually fade. Potassium from supplements can cause stomach pain, nausea, or diarrhea. Alfalfa may cause gas and loose stools. Most of these are mild and temporary.
Is this safe during pregnancy?
Calcium is likely safe within recommended amounts during pregnancy. Oats eaten as food are generally safe. However, potassium supplements require medical guidance (food potassium is fine), and alfalfa in supplement amounts should be avoided because it has estrogen-like effects. Talk with your doctor about your specific situation.
Can I take this if I'm on diabetes medication or insulin?
The oats in this product may lower your blood sugar, so combined with diabetes medication or insulin, there's a risk of your blood sugar dropping too low. Check with your doctor or pharmacist before starting—they may need to monitor your levels more closely or adjust your dose.
Is this product effective for the things it claims to do?
The calcium is effective for osteoporosis and other conditions, and the oats are likely effective for cholesterol and heart health. However, alfalfa's effectiveness isn't well established for most uses—the evidence is simply too limited to say whether it works. The beef bone broth protein and potassium don't have effectiveness ratings in our data.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Bone Broth Protein Greens label
Go deeper

The Full Monographs Behind Bone Broth Protein Greens’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Potassium

Interacts with 62 drugs

Potassium is an essential mineral your body needs for nerve signals, muscle function, and a steady heartbeat, and most people get enough from a balanced diet rich in fruits and vegetables. P...

Read the full Potassium monograph → Herb & supplement monograph

Calcium

Interacts with 168 drugs

Calcium is an essential mineral your body needs for strong bones, nerve signaling, and muscle function, and supplements can help fill gaps when diet falls short. Most people do best getting...

Read the full Calcium monograph → Herb & supplement monograph

Alfalfa

Interacts with 583 drugs

Alfalfa is a nutrient-rich legume that people use for high cholesterol, menopause symptoms, and general wellness, but solid human evidence for most of these uses is limited. It is best avoid...

Read the full Alfalfa monograph → Herb & supplement monograph

Oats

Interacts with 86 drugs

Oats are a well-studied whole grain whose soluble fiber (beta-glucan) can help lower cholesterol and support heart health when eaten regularly. As a food, oats are safe for most people, and...

Read the full Oats monograph →
Sources

Sources & How We Checked

Bone Broth Protein Greens's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 119 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Potassium 12 references
  1. McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
  2. Gennaro A. Remington: The Science and Practice of Pharmacy. 19th ed. Lippincott: Williams & Wilkins, 1996.
  3. Whelton PK, He J, Cutler JA, et al. Effects of oral potassium on blood pressure. Meta-analysis of randomized controlled clinical trials. JAMA 1997;277:1624-32. PubMed
  4. Phillips, C. O., Kashani, A., Ko, D. K., Francis, G., and Krumholz, H. M. Adverse effects of combination angiotensin II receptor blockers plus angiotensin-converting enzyme inhibitors for left ventricular dysfunction: a quantitative review of data from ra DOI
  5. Altieri, P. I., Herrero, C., Suero, R., and Ortiz, A. Bleeding duodenal ulcer in a patient taking slow-releasing potassium tablets. Bol.Asoc.Med P.R. 1977;69(8):276.
  6. Raf, L. E. Enteric-coated potassium chloride tablets and ulcer of the small intestine. Acta Chir Scand Suppl 1967;(374):1-87.
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Alfalfa 32 references
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Oats 13 references
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See these in context on the Oats monograph →

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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

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