Major interaction on record — check this product against your medications before combining. Based on 3 of 4 ingredients. Check your meds →
Dietary supplement

Carotene Formula Ingredients & Drug Interactions

by Beyond Health

Softgel Capsule Category: Other Combinations
Most serious interaction: Major
The interaction bottom line Most serious interaction: Major

Carotene Formula is a dietary supplement by Beyond Health with 4 active ingredients. Its ingredients are commonly taken for eye and vision health, skin health and acne, immune support.Based on those ingredients, 459 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Betatene. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Carotene Formula by Beyond Health

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 6 of its 6 active ingredients.
  • “Unsaturated Fat” is listed as a grouped ingredient — the label gives one combined amount (224.07 mg) without saying how much of each component you get.
  • “Betatene” is listed as a grouped ingredient — the label gives one combined amount (25,000 IU) without saying how much of each component you get.

Carotene Formula contains 6 active ingredients, all carotenoids (plant pigments with antioxidant properties). The main ones are lutein, zeaxanthin, and alpha-carotene — compounds your body uses to support eye and overall health.

The formula also includes cryptoxanthin and a blend called Betatene, which delivers beta-carotene and other carotenoid components. These are delivered in a softgel capsule with soybean oil and other inactive ingredients (bovine gelatin, glycerin, beeswax, soy lecithin, vitamin E, and purified water) that help your body absorb the carotenoids.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded its ingredients' overall clinical evidence instead.

Moderate

Some clinical evidence supports its ingredients for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredients' overall clinical evidence instead.
  • On file: Age-related macular degeneration (AMD) — rated "Possibly Effective" (Lutein) (Natural Medicines).
  • On file: Cataracts — rated "Possibly Effective" (Lutein) (Natural Medicines).

Lutein and zeaxanthin are both rated possibly effective for age-related macular degeneration (AMD), an eye condition that can cause vision loss as you age. Lutein is also rated possibly effective for cataracts.

For other conditions — including Alzheimer's disease, asthma, breast cancer, and several others — the evidence for these ingredients is too thin to rate, or research suggests they may not work (such as for retinitis pigmentosa and retinopathy of prematurity). The data we hold doesn't establish effectiveness for other claimed uses.

The evidence, ingredient by ingredient Vitamin A Zeaxanthin Lutein

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Lutein and zeaxanthin are generally well tolerated at typical supplement doses. No adverse effects were documented in trials of lutein up to 20 mg daily.

For pregnancy, both ingredients are rated likely safe, though the facts note that safety data on supplement doses (rather than food amounts) in pregnancy isn't well studied, so caution is advised — talk with your doctor about whether to take this while pregnant. Similarly, for breastfeeding, food sources are fine, but there isn't enough data on concentrated supplements, so check with your doctor or pharmacist before use.

Side effects, ingredient by ingredient Vitamin A Zeaxanthin Lutein

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 2 matched ingredients can interact with medications — Zeaxanthin.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 86 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

The main medication type to double-check is antidiabetes drugs (blood sugar medications). Zeaxanthin in this formula may theoretically increase the risk of low blood sugar when combined with these drugs.

Use the search tool on this page to run your exact medications against the ingredients.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.

This formula is a reasonable choice if you're looking to support eye health, especially for AMD or cataracts, though results depend on the strength of evidence for those conditions. If you take antidiabetes medications, you'll want to check your exact drugs with your pharmacist before starting, since zeaxanthin may affect blood sugar control.

Pregnant or breastfeeding? Talk it over with your doctor first — there's enough caution in the data that you'll want personalized advice.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 6 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Mar 22, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Carotene Formula, straight from the product label.

Brand Beyond Health
Net contents 90 Softgel(s)
Market status On market
Date entered into DSLD Mar 22, 2024
DSLD ID 306879
Product type Other Combinations
Supplement form Softgel Capsule
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Carotene Formula by Beyond Health, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Softgel(s)
Maximum serving Sizes:
1 Softgel(s)
Servings per container
90
IngredientAmount% DV
Protein121.48 mg1%
Trans Fat0.68 mg--
Cholesterol0 mg--
Total Fat266.87 mg1%
Polyunsaturated Fat124.83 mg--
Monounsaturated Fat99.24 mg--
Saturated Fat42.13 mg1%
Total Carbohydrate61.48 mg1%
Unsaturated Fat224.07 mg--
Total Calories3.13 Calorie(s)--
Betatene25000 IU500%
Alpha-Carotene750 mcg--
Cryptoxanthin215 mcg--
Zeaxanthin107 mcg--
Lutein107 mcg--

Other ingredients: Soybean Oil, Bovine Gelatin, Glycerin, Water, Purified, yellow Beeswax, Soy Lecithin, Vitamin E

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Brand IP Statement(s)

Beyond Health Helping you get well and stay well One disease Two causes Six pathways

Betatene is a registered trademark of Cognis Nutrition and Health, Corp.

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Directions: As a dietary supplement, take 1 softgel capsule daily with food, or as directed by a health care professional.

General Statements

World class supplements

Precautions

Keep out of reach of children.

Do not use if the tamper-resistant shrink band around the cap or the inner seal below the cap appears to have been tampered with or is missing.

Storage

Must be stored with cap on tightly.

Formulation

Does not contain: Wheat, rye, oats, corn, barley, gluten, eggs, shellfish, sugar, yeast, sulfates, chlorides, phosphates, wax (other than beeswax), preservatives, colorings, or artificial flavorings. No GMOs Typical values based on manufactures specification.

Manufactured in the U.S.A.

See for yourself

Carotene Formula by Beyond Health label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Carotene Formula by Beyond Health

These are the 4 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Softgel(s) Dosage formSoftgel Capsule Servings per container90 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Protein

121.48 mg per serving

Unsaturated Fat

224.07 mg per serving

Total Calories

3.13 Calorie(s) per serving

Betatene

Interacts with
387 drugs
25000 IU per serving Form: Vitamin A

Vitamin A is an essential nutrient important for vision, skin, immune function, and growth. Most people get enough from a balanced diet, and supplemen...

Betatene monograph & interactions

Other (inactive) ingredients: Soybean Oil, Bovine Gelatin, Glycerin, Water, Purified, Yellow Beeswax, Soy Lecithin, Vitamin E. These complete the product’s ingredient list but are not active constituents.

Interaction report

Carotene Formula by Beyond Health Drug Interactions

Want to check YOUR meds against Carotene Formula?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
459Drugs
9 Major 450 Moderate

Ingredients driving the most interactions

Betatene 387

Each ingredient & the kinds of drugs it affects

For each ingredient in Carotene Formula with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Betatene4 drug types · 387 drugs

Retinoids

Concomitant use of retinoids with vitamin A supplements might produce supratherapeutic vitamin A levels.
Retinoids, which are vitamin A derivatives, could have additive toxic effects when taken with vitamin A supplements.

Likelihood Probable Evidence D
Hepatotoxic Drugs

Theoretically, taking high doses of vitamin A in combination with other potentially hepatotoxic drugs might increase the risk of liver disease.
The tolerable upper intake level (UL) is the highest level of intake that is likely to pose no risk of adverse effects. Doses of vitamin A above the UL can cause hepatotoxicity, ranging from elevated liver enzymes to liver failure.

Likelihood Possible Evidence C
Tetracycline Antibiotics

Theoretically, taking tetracycline antibiotics with high doses of vitamin A can increase the risk of pseudotumor cerebri.
Benign intracranial hypertension (pseudotumor cerebri) can occur with tetracyclines and with acute or chronic vitamin A toxicity. Case reports suggest that taking tetracyclines and vitamin A concurrently can increase the risk of this condition. Avoid high doses of vitamin A in people taking tetracyclines chronically.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Theoretically, high doses of vitamin A could increase the risk of bleeding with warfarin.
Vitamin A toxicity is associated with hemorrhage and hypoprothrombinemia, possibly due to vitamin K antagonism. Advise patients taking warfarin to avoid doses of vitamin A above the tolerable upper intake level of 10,000 IU/day for adults.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Carotene Formula, from the product label.

Beyond Health

See all Beyond Health products
Name
Beyond Health International
Street Address
6555 Powerline Road, #101
City
Fort Lauderdale
State
FL
ZipCode
33309
Phone Number
800-250-3063
Web Address
www.beyondhealth.com
Pharmacist Counseling Corner

Carotene Formula by Beyond Health: Common Questions

Does Carotene Formula by Beyond Health interact with any medications?
Yes. Based on its ingredients, Carotene Formula has a known interaction with 459 medications, including 9 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Carotene Formula contains 4 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will this help my eye health?
Lutein and zeaxanthin, both in this formula, are rated possibly effective for age-related macular degeneration and cataracts — common eye conditions that develop with age. For other eye or health conditions, the evidence isn't established in our data.
Is it safe to take while pregnant?
Both lutein and zeaxanthin are rated likely safe in pregnancy, but the data notes that safety of supplement doses (not just food sources) isn't well studied. Talk with your doctor before starting — they can weigh the benefits and risks for your situation.
Can I take this while breastfeeding?
Both ingredients are rated likely safe, and lutein naturally appears in breast milk. However, safety of higher supplement doses during breastfeeding isn't well studied, so check with your doctor or pharmacist before use.
What are all these carotenoids for?
Carotenoids are plant pigments your body uses for eye health and antioxidant protection. This formula includes lutein, zeaxanthin, alpha-carotene, and cryptoxanthin — all work together to support vision and cellular health.
I take a blood sugar medication. Can I use this?
Zeaxanthin in this formula may theoretically increase the risk of low blood sugar with antidiabetes drugs. Use the search tool on this page to check your exact medication, and talk with your pharmacist before starting.
What are the inactive ingredients?
The softgel capsule contains soybean oil, bovine gelatin, glycerin, purified water, yellow beeswax, soy lecithin, and vitamin E — these help absorb and deliver the active carotenoids.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Carotene Formula is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Carotene Formula label
Sources

Sources & How We Checked

Carotene Formula's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 37 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Vitamin A 31 references
  1. McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
  2. Griffiths JK. The vitamin A paradox. J Pediatr 2000;137:604-7.. PubMed
  3. Hardman JG, Limbird LL, Molinoff PB, eds. Goodman and Gillman's The Pharmacological Basis of Therapeutics, 9th ed. New York, NY: McGraw-Hill, 1996.
  4. Hansten PD, Horn JR. Drug Interactions Analysis and Management. Vancouver, WA: Applied Therapeutics Inc., 1997 and updates.
  5. FDA Talk Paper. Vitamin A and birth defects (T95-56). Food and Drug Administration, U.S. Department of Health and Human Services, Rockville, MD. October 6, 1995.
  6. Russell RM. The vitamin A spectrum: from deficiency to toxicity. Am J Clin Nutr 2000;71:878-84. PubMed
  7. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. Washington, DC: National Academy Press, 2002.
  8. Feskanich D, Singh V, Willett WC, Colditz GA. Vitamin A intake and hip fractures among postmenopausal women. JAMA 2002;287:47-54. PubMed
  9. Melhus H, Michaelsson K, Kindmark A, et al. Excessive dietary intake of vitamin A is associated with reduced bone mineral density and increased risk for hip fracture. Ann Intern Med 1998;129:770-8. PubMed
  10. Michaelsson K, Lithell H, Vessby B, Melhus H. Serum retinol levels and the risk of fracture. N Engl J Med 2003;348:287-94.. PubMed
  11. Botterweck AA, van den Brandt PA, Goldbohm RA. Vitamins, carotenoids, dietary fiber, and the risk of gastric carcinoma: results from a prospective study after 6.3 years of follow-up. Cancer 2000;88:737-48.. DOI
  12. Meyskens FL Jr, Graham V, Chvapil M, et al. A phase I trial of beta-all-trans-retinoic acid delivered via a collagen sponge and a cervical cap for mild or moderate intraepithelial cervical neoplasia. J Natl Cancer Inst 1983;71:921-5..
  13. Hathcock JN, Hattan DG, Jenkins MY, et al. Evaluation of vitamin A toxicity. Am J Clin Nutr 1990;52:183-202.. PubMed
  14. Walters BN, Gubbay SS. Tetracycline and benign intracranial hypertension: report of five cases. Br Med J 1981;282:19-20.. PubMed
  15. Pearson MG, Littlewood SM, Bowden AN. Tetracycline and benign intracranial hypertension (letter). Br Med J 1981;282:568-9.. PubMed
  16. Azais-Braesco V, Pascal G. Vitamin A in pregnancy: requirements and safety limits. Am J Clin Nutr 2000;71:1325S-33S. PubMed
  17. Smedts HP, de Vries JH, Rakhshandehroo M, et al. High maternal vitamin E intake by diet or supplements is associated with congenital heart defects in the offspring. BJOG 2009;116:416-23. PubMed
  18. Grotto, I., Mimouni, M., Gdalevich, M., and Mimouni, D. Vitamin A supplementation and childhood morbidity from diarrhea and respiratory infections: a meta-analysis. J Pediatr 2003;142(3):297-304. PubMed
  19. Mahalanabis, D., Lahiri, M., Paul, D., Gupta, S., Gupta, A., Wahed, M. A., and Khaled, M. A. Randomized, double-blind, placebo-controlled clinical trial of the efficacy of treatment with zinc or vitamin A in infants and young children with severe acute l
  20. Long, K. Z., Montoya, Y., Hertzmark, E., Santos, J. I., and Rosado, J. L. A double-blind, randomized, clinical trial of the effect of vitamin A and zinc supplementation on diarrheal disease and respiratory tract infections in children in Mexico City, Mex
  21. Fritz, H., Kennedy, D., Fergusson, D., Fernandes, R., Doucette, S., Cooley, K., Seely, A., Sagar, S., Wong, R., and Seely, D. Vitamin A and retinoid derivatives for lung cancer: a systematic review and meta analysis. PLoS.One. 2011;6(6):e21107. PubMed
  22. Mayo-Wilson, E., Imdad, A., Herzer, K., Yakoob, M. Y., and Bhutta, Z. A. Vitamin A supplements for preventing mortality, illness, and blindness in children aged under 5: systematic review and meta-analysis. BMJ 2011;343:d5094. PubMed
  23. Mazumder S, Taneja S, Bhatia K, Yoshida S, Kaur J, Dube B, Toteja GS, Bahl R, Fontaine O, Martines J, Bhandari N; Neovita India Study Group. Efficacy of early neonatal supplementation with vitamin A to reduce mortality in infancy in Haryana, India (Neovit
  24. Baineni R, Gulati R, Delhi CK. Vitamin A toxicity presenting as bone pain. Arch Dis Child. 2017;102(6):556-8. PubMed
  25. Darlow BA, Graham PJ, Rojas-Reyes MX. Vitamin A supplementation to prevent mortality and short- and long-term morbidity in very low birth weight infants. Cochrane Database Syst Rev. 2016;(8):CD000501. PubMed
  26. Haider BA, Sharma R, Bhutta ZA. Neonatal vitamin A supplementation for the prevention of mortality and morbidity in term neonates in low and middle income countries. Cochrane Database Syst Rev. 2017;2:CD006980. PubMed
  27. Mohammad YM, Raslan IR, Al-Hussain FA. Idiopathic Intracranial Hypertension Induced by Topical Application of Vitamin A. J Neuroophthalmol. 2016;36(4):412-3. PubMed
  28. Masnadi Shirazi K, Nikniaz Z, Masnadi Shirazi A, Rohani M. Vitamin A supplementation decreases disease activity index in patients with ulcerative colitis: A randomized controlled clinical trial. Complement Ther Med. 2018 Dec;41:215-219. PubMed
  29. Ding Y, Hu P, Yang Y, et al. Impact of maternal daily oral low-dose vitamin A supplementation on the mother-infant pair: a randomised placebo-controlled trial in China. Nutrients 2021;13(7):2370. PubMed
  30. Knapik JJ, Hoedebecke SS. Vitamin A and bone fractures: systematic review and meta-analysis. J Spec Oper Med 2021;21(2):100-7. PubMed
  31. Imdad A, Mayo-Wilson E, Haykal MR, et al. Vitamin A supplementation for preventing morbidity and mortality in children from six months to five years of age. Cochrane Database Syst Rev 2022;3(3):CD008524. PubMed

See these in context on the Vitamin A monograph →

Zeaxanthin 4 references
  1. Montonen J, Knekt P, Jarvinen R, Reunanen A. Dietary antioxidant intake and risk of type 2 diabetes. Diabetes Care 2004;27:362-6. PubMed
  2. Leermakers ET, Darweesh SK, Baena CP, et al. The effects of lutein on cardiometabolic health across the life course: a systematic review and meta-analysis. Am J Clin Nutr 2016;103(2):481-94. PubMed
  3. Kou L, Du M, Zhang C, Dai Z, Li X, Zhang B. The Hypoglycemic, Hypolipidemic, and Anti-Diabetic Nephritic Activities of Zeaxanthin in Diet-Streptozotocin-Induced Diabetic Sprague Dawley Rats. Appl Biochem Biotechnol 2017;182(3):944-955. PubMed
  4. Xu X, Zhao X, Berde Y, Low YL, Kuchan MJ. Milk and Plasma Lutein and Zeaxanthin Concentrations in Chinese Breast-Feeding Mother-Infant Dyads With Healthy Maternal Fruit and Vegetable Intake. J Am Coll Nutr 2019;38(2):179-184. PubMed

See these in context on the Zeaxanthin monograph →

Lutein 2 references
  1. Brown L, Rimm EB, Seddon JM, et al. A prospective study of carotenoid intake and risk of cataract extraction in US men. Am J Clin Nutr 1999;70:517-24. PubMed
  2. Chasan-Taber L, Willett WC, Seddon JM, et al. A prospective study of carotenoid and vitamin A intakes and risk of cataract extraction in US women. Am J Clin Nutr 1999;70:509-16. PubMed

See these in context on the Lutein monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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