Castor Oil Softgels Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Castor Oil Softgels against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Castor Oil Softgels is a dietary supplement by Baar Nature's Blessing with 2 active ingredients. Its ingredients are commonly taken for digestive upset and bloating, infant colic, menstrual cramps.Based on those ingredients, 740 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Fennel oil. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Castor Oil Softgels by Baar Nature's Blessing
Ask about any prescription or over-the-counter medication and we check it for interactions with Castor Oil Softgels by Baar Nature's Blessing — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Castor Oil Softgels by Baar Nature's Blessing
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This softgel contains 2 active ingredients: fennel oil and castor oil. Fennel oil has traditionally been used for digestive comfort and other purposes, while castor oil is a well-known natural laxative.
The softgels also contain inactive ingredients — bovine gelatin (the capsule), glycerin, and water — that help deliver the oils.
Does it work?
Insufficient evidence
Fennel oil is rated possibly effective for dysmenorrhea (painful periods). For other uses listed — bronchitis, anxiety, bedwetting, and cholera — the evidence we hold is insufficient to rate.
Castor oil's effectiveness data isn't available in our records. If you're considering this product for a specific condition, talk with your pharmacist about what the research actually shows.
How safe is it?
Well-documented data
Fennel oil is generally well tolerated when taken by mouth, though some people report gastrointestinal discomfort, sensitivity to sunlight, or allergic reactions. Rarely, seizures have been reported.
Allergic reactions can be serious — if you experience wheezing, difficulty breathing, or throat symptoms, stop and seek help right away. The safety data advises against medicinal or concentrated amounts during pregnancy.
While food amounts are likely fine, medicinal doses and fennel essential oil aren't well studied during breastfeeding, so talk with your doctor or pharmacist for personalized advice.
Meds to double-check
Moderate interaction found
Before taking this product, double-check with your pharmacist if you're on blood thinners or antiplatelet drugs, birth control pills or hormone replacement therapy, the antibiotic ciprofloxacin, tamoxifen, or any medication your liver metabolizes. These are the medication types with documented interactions with the fennel oil in this product.
The bottom line
Scorecard at a glanceFully disclosed formula with insufficient evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
This product may work for period pain, but fennel oil's interactions with blood thinners, birth control, hormone therapy, and several other medications make it important to check before you start. If you're pregnant or breastfeeding, discuss it with your pharmacist first.
It's generally well tolerated, but allergic reactions can happen.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jul 24, 2025.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Castor Oil Softgels, straight from the product label.
| Brand | Baar Nature's Blessing |
|---|---|
| Barcode (UPC) | 813478008337 |
| Net contents | 120 Softgel(s) |
| Market status | On market |
| Date entered into DSLD | Jul 24, 2025 |
| DSLD ID | 334199 |
| Product type | Botanical |
| Supplement form | Softgel Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Women (not pregnant or lactating), Gluten Free, Dairy Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Castor Oil Softgels by Baar Nature's Blessing, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Calories | 5 Calorie(s) | -- |
| Total Fat | 0.5 Gram(s) | 1% |
| Fennel oil | 10 mg | -- |
| Castor Oil | 650 mg | -- |
Other ingredients: Bovine Gelatin, Glycerin, Water
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Suggested usage: Take 1 softgel 1 to 2 times daily with food as needed.
Formula
Castor oil is an oil derived from the beans of the castor plant (Ricinus communis). Castor oil has long been recognized as a powerful laxative that may be used for the relief of occasional constipation.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Precautions
Caution: For adults only. Keep out of reach of children.
Castor oil is a laxative.
This product is not intended for pregnant or nursing women. Consult physician if taking medication or have a medical condition (including any gastric or intestinal disorders).
Do not exceed recommended dose. This product is not intended for long term use. Discontinue use if gastric upset or diarrhea occurs.
Not manufactured with yeast, wheat, gluten, soy, corn, milk, egg, fish or shellfish ingredients. Produced in a GMP facility that processes other ingredients containing these allergens.
Formulation
Natural color variation may occur in product.
Natural laxative Cold pressed, hexane-free
Cold pressed, hexane-free
Not manufactured with yeast, wheat, gluten, soy, corn, milk, egg, fish or shellfish ingredients.
Non-GMO
FDA Statement of Identity
A Dietary Supplement
Seals/Symbols
GMP
Storage
Store in a cool, dry place after opening.
General Statements
Please recycle.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Castor Oil Softgels by Baar Nature's Blessing label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Castor Oil Softgels by Baar Nature's Blessing
These are the 2 active ingredients this product is made of. Select any to open its full monograph.
Serving size1 Softgel(s) Dosage formSoftgel Capsule Servings per container120 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Fennel oil
Interacts with740 drugs
Fennel is a Mediterranean herb widely used as a food and spice, and traditionally taken for digestive complaints, colic, and menstrual cramps. Some sm...
Fennel oil monograph & interactionsCastor Oil
Other (inactive) ingredients: Bovine Gelatin, Glycerin, Water. These complete the product’s ingredient list but are not active constituents.
Castor Oil Softgels by Baar Nature's Blessing Drug Interactions
HelloPharmacist Interaction Report
Baar Nature's Blessing Castor Oil Softgels contains fennel oil, which has documented interactions with several medication types.
The most serious concern is with blood thinners and antiplatelet drugs (anticoagulants/antiplatelets) — fennel oil may increase bleeding risk when combined with these medications.
Read the full breakdown — every affected drug type, severity by severity
Fennel oil may also interfere with birth control pills and hormone replacement therapy by competing for estrogen receptors, potentially reducing their effectiveness. It could raise levels of certain drugs your liver breaks down (CYP3A4 substrates), and animal research suggests it might lower blood levels of the antibiotic ciprofloxacin by nearly half.
Additionally, it may reduce the effectiveness of tamoxifen, a breast cancer medication with hormone-blocking activity.
We could not check castor oil itself — we hold no interaction data for it. Altogether, these interactions span 730 individual medications.
Before you start this product, run your exact medications through the checker on this page, especially if you take blood thinners, birth control, hormone therapy, ciprofloxacin, tamoxifen, or medications your liver processes.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Castor Oil Softgels?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Castor Oil Softgels interact with 740 drugs. Click any drug to see the details.
1 of the 2 ingredients in Castor Oil Softgels interact with drugs. Each result below shows which ingredient is responsible. Fennel oil
Ado-trastuzumab EmtansineKadcyla
How Ado-trastuzumab Emtansine interacts with Castor Oil Softgels — through 1 ingredient. Tap an ingredient for the detail:
Fennel OilCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
Read the full Fennel Oil + Ado-trastuzumab Emtansine interactionAbciximabReoPro
How Abciximab interacts with Castor Oil Softgels — through 1 ingredient. Tap an ingredient for the detail:
Fennel OilAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fennel might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Read the full Fennel Oil + Abciximab interactionAbemaciclibVerzenio
How Abemaciclib interacts with Castor Oil Softgels — through 1 ingredient. Tap an ingredient for the detail:
Fennel OilCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
Read the full Fennel Oil + Abemaciclib interactionAbiraterone
How Abiraterone interacts with Castor Oil Softgels — through 1 ingredient. Tap an ingredient for the detail:
Fennel OilCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
Read the full Fennel Oil + Abiraterone interactionAbiraterone AcetateYonsa, Zytiga
How Abiraterone Acetate interacts with Castor Oil Softgels — through 1 ingredient. Tap an ingredient for the detail:
Fennel OilCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
Read the full Fennel Oil + Abiraterone Acetate interactionAbrocitinibCibinqo
How Abrocitinib interacts with Castor Oil Softgels — through 1 ingredient. Tap an ingredient for the detail:
Fennel OilAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fennel might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Read the full Fennel Oil + Abrocitinib interactionAcalabrutinibCalquence
How Acalabrutinib interacts with Castor Oil Softgels — through 1 ingredient. Tap an ingredient for the detail:
Fennel OilCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
Read the full Fennel Oil + Acalabrutinib interactionAcenocoumarolSintrom
How Acenocoumarol interacts with Castor Oil Softgels — through 1 ingredient. Tap an ingredient for the detail:
Fennel OilAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fennel might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Read the full Fennel Oil + Acenocoumarol interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Castor Oil Softgels — through 1 ingredient. Tap an ingredient for the detail:
Fennel OilAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fennel might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Read the full Fennel Oil + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Castor Oil Softgels — through 1 ingredient. Tap an ingredient for the detail:
Fennel OilAnticoagulant/antiplatelet Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Read the full Fennel Oil + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, Butalbital, CaffeineEsgic, Esgic Plus, Fiogesic, Fioricet, Repan, Tecnal +1 more
How Acetaminophen, Butalbital, Caffeine interacts with Castor Oil Softgels — through 1 ingredient. Tap an ingredient for the detail:
Fennel OilCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
Read the full Fennel Oil + Acetaminophen, Butalbital, Caffeine interactionAcetaminophen, Butalbital, Caffeine, CodeineEsgic with Codeine, Fioricet w/ Codeine
How Acetaminophen, Butalbital, Caffeine, Codeine interacts with Castor Oil Softgels — through 1 ingredient. Tap an ingredient for the detail:
Fennel OilCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
Read the full Fennel Oil + Acetaminophen, Butalbital, Caffeine, Codeine interactionAcetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, PhenylephrineHycomine Compound
How Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interacts with Castor Oil Softgels — through 1 ingredient. Tap an ingredient for the detail:
Fennel OilCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
Read the full Fennel Oil + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionAcetaminophen, Caffeine, CodeineGesic C15, Gesic C30, Gesic C8, Lenoltec 1, Lenoltec 2, Lenoltec 3 +1 more
How Acetaminophen, Caffeine, Codeine interacts with Castor Oil Softgels — through 1 ingredient. Tap an ingredient for the detail:
Fennel OilCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
Read the full Fennel Oil + Acetaminophen, Caffeine, Codeine interactionAcetaminophen, Caffeine, Codeine, SalicylamideCodalan No.1, Codalan No.2, Codalan No.3
How Acetaminophen, Caffeine, Codeine, Salicylamide interacts with Castor Oil Softgels — through 1 ingredient. Tap an ingredient for the detail:
Fennel OilCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
Read the full Fennel Oil + Acetaminophen, Caffeine, Codeine, Salicylamide interactionAcetaminophen, Caffeine, DihydrocodeineDHC Plus, Panlor DC, Panlor SS
How Acetaminophen, Caffeine, Dihydrocodeine interacts with Castor Oil Softgels — through 1 ingredient. Tap an ingredient for the detail:
Fennel OilCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
Read the full Fennel Oil + Acetaminophen, Caffeine, Dihydrocodeine interactionAcetaminophen, Caffeine, IsomethepteneMigralam
How Acetaminophen, Caffeine, Isometheptene interacts with Castor Oil Softgels — through 1 ingredient. Tap an ingredient for the detail:
Fennel OilCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
Read the full Fennel Oil + Acetaminophen, Caffeine, Isometheptene interactionAcetaminophen, Caffeine, PyrilamineMidol Max Strength Menstrual
How Acetaminophen, Caffeine, Pyrilamine interacts with Castor Oil Softgels — through 1 ingredient. Tap an ingredient for the detail:
Fennel OilCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
Read the full Fennel Oil + Acetaminophen, Caffeine, Pyrilamine interactionAcetaminophen, Chlorpheniramine Maleate, Dextromethorphan HbrVicks Formula 44M Cough, Cold & Flu Relief
How Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interacts with Castor Oil Softgels — through 1 ingredient. Tap an ingredient for the detail:
Fennel OilCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
Read the full Fennel Oil + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionAcetaminophen, Chlorpheniramine, Codeine, PhenylephrineColrex
How Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interacts with Castor Oil Softgels — through 1 ingredient. Tap an ingredient for the detail:
Fennel OilCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
Read the full Fennel Oil + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, DextromethorphanCoricidin II Extra Strength Cold and Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan interacts with Castor Oil Softgels — through 1 ingredient. Tap an ingredient for the detail:
Fennel OilCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
Read the full Fennel Oil + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionAcetaminophen, Chlorpheniramine, Dextromethorphan HydrobromideCoricidin HBP Maximum Strength Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interacts with Castor Oil Softgels — through 1 ingredient. Tap an ingredient for the detail:
Fennel OilCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
Read the full Fennel Oil + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PhenylpropanolamineMulti Symptom Cold Relief
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interacts with Castor Oil Softgels — through 1 ingredient. Tap an ingredient for the detail:
Fennel OilCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
Read the full Fennel Oil + Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PseudoephedrineChildren's Tylenol Cold Plus Cough, Tylenol Cold Ex Strength
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interacts with Castor Oil Softgels — through 1 ingredient. Tap an ingredient for the detail:
Fennel OilCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
Read the full Fennel Oil + Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interactionAcetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, SalicylamideRhinogesic GG
How Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interacts with Castor Oil Softgels — through 1 ingredient. Tap an ingredient for the detail:
Fennel OilCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
Read the full Fennel Oil + Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interactionAcetaminophen, Chlorpheniramine, PhenylephrineAlka-Seltzer PLUS, Histex SR, Protid
How Acetaminophen, Chlorpheniramine, Phenylephrine interacts with Castor Oil Softgels — through 1 ingredient. Tap an ingredient for the detail:
Fennel OilCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
Read the full Fennel Oil + Acetaminophen, Chlorpheniramine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, Phenylephrine, SalicylamideRhinogesic, Rhinogesic JR
How Acetaminophen, Chlorpheniramine, Phenylephrine, Salicylamide interacts with Castor Oil Softgels — through 1 ingredient. Tap an ingredient for the detail:
Fennel OilCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
Read the full Fennel Oil + Acetaminophen, Chlorpheniramine, Phenylephrine, Salicylamide interactionAcetaminophen, Chlorpheniramine, PhenylpropanolamineAlumadrine, Conex, Sinadrin Max Strength, Sinulin
How Acetaminophen, Chlorpheniramine, Phenylpropanolamine interacts with Castor Oil Softgels — through 1 ingredient. Tap an ingredient for the detail:
Fennel OilCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
Read the full Fennel Oil + Acetaminophen, Chlorpheniramine, Phenylpropanolamine interactionAcetaminophen, Chlorpheniramine, Phenylpropanolamine, OpiumHista-Derfule
How Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Opium interacts with Castor Oil Softgels — through 1 ingredient. Tap an ingredient for the detail:
Fennel OilCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
Read the full Fennel Oil + Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Opium interactionAcetaminophen, Chlorpheniramine, Phenylpropanolamine, PhenyltoloxamineNorel Plus
How Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Phenyltoloxamine interacts with Castor Oil Softgels — through 1 ingredient. Tap an ingredient for the detail:
Fennel OilCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
Read the full Fennel Oil + Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Phenyltoloxamine interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Castor Oil Softgels with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Fennel oil
Anticoagulant/Antiplatelet Drugs
Theoretically, fennel might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Animal research suggests that fennel oil has antithrombotic and antiplatelet effects.
Ciprofloxacin (Cipro)
Theoretically, fennel might decrease the levels and clinical effects of ciprofloxacin.
Animal research shows that fennel reduces ciprofloxacin bioavailability by nearly 50%, possibly due to the metal cations such as calcium, iron, and magnesium contained in fennel. This study also found that fennel increased tissue distribution and slowed elimination of ciprofloxacin.
Contraceptive Drugs
Theoretically, taking large amounts of fennel might decrease the effects of contraceptive drugs due to competition for estrogen receptors.
Some constituents of fennel have estrogenic activity.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
In vitro research suggests that fennel inhibits CYP3A4 enzyme activity. This effect has not been reported in humans.
Estrogens
Theoretically, taking large amounts of fennel might interfere with hormone replacement therapy due to competition for estrogen receptors.
Some constituents of fennel have estrogenic activity.
Tamoxifen (Nolvadex)
Theoretically, taking large amounts of fennel might decrease the antiestrogenic effect of tamoxifen.
Some constituents of fennel have estrogenic activity, which may interfere with the antiestrogenic activity of tamoxifen.
Brand information
Manufacturer and brand details for Castor Oil Softgels, from the product label.
Baar Nature's Blessing
See all Baar Nature's Blessing products- Name
- Baar Products, Inc
- City
- Downingtown
- State
- PA
- ZipCode
- 19335
- Phone Number
- 1-800-269-2502
- Web Address
- www.baar.com
Castor Oil Softgels by Baar Nature's Blessing: Common Questions
Does Castor Oil Softgels by Baar Nature's Blessing interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
What is fennel oil used for in this product?
Can I take this if I'm on birth control?
What are the side effects of fennel oil?
Is this safe to take during pregnancy?
Can I take this while breastfeeding?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Castor Oil Softgels is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Castor Oil Softgels’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Castor Oil Softgels's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 17 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Fennel 17 references
- Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics. 2nd ed. New York, NY: John Wiley & Sons, 1996.
- Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
- Zhu M, Wong PY, Li RC. Effect of oral administration of fennel (Foeniculum vulgare) on ciprofloxacin absorption and disposition in the rat. J Pharm Pharmacol 1999;51:1391-6.
- Gral N, Beani JC, Bonnot D, et al. [Plasma levels of psoralens after celery ingestion]. Ann Dermatol Venereol 1993;120:599-603.
- Burkhard PR, Burkhardt K, Haenggeli CA, Landis T. Plant-induced seizures: reappearance of an old problem. J Neurol 1999;246:667-70. PubMed
- Rosti L, Nardini A, Bettinelli ME, Rosti D. Toxic effects of a herbal tea mixture in two newborns. Acta Paediatrica 1994;83:683. PubMed
- Cuzzolin L, Zaffani S, and Benoni G. Safety implications regarding use of phytomedicines. Eur.J Clin Pharmacol. 2006;62:37-42. PubMed
- Tognolini, M., Ballabeni, V., Bertoni, S., Bruni, R., Impicciatore, M., and Barocelli, E. Protective effect of Foeniculum vulgare essential oil and anethole in an experimental model of thrombosis. Pharmacol.Res 2007;56(3):254-260. PubMed
- Subehan, Usia, T., Iwata, H., Kadota, S., and Tezuka, Y. Mechanism-based inhibition of CYP3A4 and CYP2D6 by Indonesian medicinal plants. J Ethnopharmacol. 5-24-2006;105(3):449-455. PubMed
- Tognolini, M., Barocelli, E., Ballabeni, V., Bruni, R., Bianchi, A., Chiavarini, M., and Impicciatore, M. Comparative screening of plant essential oils: phenylpropanoid moiety as basic core for antiplatelet activity. Life Sci. 2-23-2006;78(13):1419-1432. PubMed
- Subehan, Zaidi, S. F., Kadota, S., and Tezuka, Y. Inhibition on human liver cytochrome P450 3A4 by constituents of fennel (Foeniculum vulgare): identification and characterization of a mechanism-based inactivator. J Agric.Food Chem. 12-12-2007;55(25):101 PubMed
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