Major interaction on record — check this product against your medications before combining. Check your meds →
Dietary supplement

Charcoal Supreme Ingredients & Drug Interactions

by HealthForce SuperFoods

Charcoal Supreme label
See full label image
Capsule Category: Other Combinations
Most serious interaction: Major
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Charcoal Supreme against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Major

Charcoal Supreme is a dietary supplement by HealthForce SuperFoods with 5 active ingredients. Its ingredients are commonly taken for poisoning and drug overdose (in emergency care), gas and bloating, upset stomach.Based on those ingredients, 2,163 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are activated Coconut Charcoal, Carob, Chlorella Algae. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Charcoal Supreme by HealthForce SuperFoods

Ask about any prescription or over-the-counter medication and we check it for interactions with Charcoal Supreme by HealthForce SuperFoods — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Charcoal Supreme by HealthForce SuperFoods

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 12, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 5 of its 5 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

Charcoal Supreme contains five active ingredients. Activated coconut charcoal is a form of carbon processed to be highly porous and is used to bind substances in your digestive tract.

Chlorella algae is a single-celled green algae. Carob is a plant source often used as a chocolate substitute or thickening agent.

Shiitake mushroom fruiting body extract comes from the cap of the mushroom. Shilajit resin extract is a mineral-rich substance found in mountain rock deposits.

The product also contains pullulan, an inactive ingredient used as a capsule material.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded its ingredients' overall clinical evidence instead.

Moderate

Some clinical evidence supports its ingredients for:

Why this rating?
  • The label markets general wellness (“detox and digestive support”), not a specific health condition, so there is no single claim to grade against clinical-evidence data.
  • Since the label doesn't commit to one use, we graded the ingredients' overall clinical evidence instead.
  • On file: Poisoning — rated "Possibly Effective" (Activated Charcoal) (Natural Medicines).
  • On file: Diarrhea — rated "Possibly Effective" (Carob) (Natural Medicines).
  • On file: Pregnancy-related iron deficiency — rated "Possibly Effective" (Chlorella) (Natural Medicines).

The evidence for what this product can actually do is quite limited. Activated charcoal is possibly effective for poisoning, but the data on it for other uses — including wound healing, indigestion, hangover, and high cholesterol — is insufficient to rate.

Chlorella may help with pregnancy-related low iron, but evidence for brain tumors, liver disease, depression, and fatigue is insufficient. Carob is possibly effective for diarrhea.

Shiitake mushroom's effectiveness for dental plaque is possibly not established; for cancer-related conditions and atherosclerosis, evidence is insufficient. Shilajit's evidence for memory, sexual function, athletic performance, prostate health, and bone density is all insufficient to rate at this time.

The evidence, ingredient by ingredient Activated Charcoal Chlorella Carob Shiitake Mushroom Shilajit

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 5 of the 5 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 5 of 5.
  • General safety write-ups exist for 5 of 5.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Activated charcoal is generally well tolerated for short-term use but commonly causes constipation, black stools, bloating, abdominal pain, and gas. Rarely, it can cause intestinal blockage.

It's possibly safe in pregnancy but not well studied, so use only under medical guidance. Chlorella is generally tolerated but has not been well studied for routine use — it can cause allergic reactions, diarrhea, constipation, nausea, fatigue, and photosensitivity (sun sensitivity).

Carob is safe in normal food amounts, though concentrated supplement doses aren't well studied. Shiitake as food is generally fine, but concentrated supplements lack adequate safety data; raw shiitake can cause a skin rash and abdominal discomfort.

Shilajit carries a contamination risk from heavy metals — use only purified, tested brands — and is best avoided in pregnancy and while breastfeeding due to insufficient safety data.

Side effects, ingredient by ingredient Activated Charcoal Chlorella Carob Shiitake Mushroom Shilajit

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 5 of the 5 matched ingredients can interact with medications — Activated Charcoal, Carob, Shiitake Mushroom, Chlorella, Shilajit.
  • The most serious interaction on file is rated Major.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; immunosuppressants / transplant drugs; diabetes medications.
  • For scale: 2,164 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking Charcoal Supreme, double-check with your pharmacist if you take oral medications (activated charcoal can reduce their absorption — Major interaction), birth control pills (Moderate interaction), diabetes drugs (Moderate interaction), blood thinners like warfarin (Moderate interaction), or drugs sensitive to sun exposure (Moderate interaction). The shiitake and shilajit may affect additional drugs, but that data isn't fully documented.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence behind its ingredients' uses. Major medication interactions have been identified, and safety information is well characterized.

Charcoal Supreme is a multi-ingredient supplement whose components aren't well proven for most claims. The activated charcoal poses a Major risk of reducing how your other medications work, especially oral drugs and birth control.

If you take any prescription medications, blood thinners, or birth control, talk to your pharmacist before starting this product. People on diabetes or immunosuppressant medications should also check first.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 5 of 5 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Sep 22, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Charcoal Supreme, straight from the product label.

Brand HealthForce SuperFoods
Barcode (UPC) 650786004350
Net contents 120 Vegan Cap(s)
Market status On market
Date entered into DSLD Sep 22, 2022
DSLD ID 270174
Product type Other Combinations
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Kosher, Organic, Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Charcoal Supreme by HealthForce SuperFoods, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
3 Vegan Capsule(s)
Maximum serving Sizes:
3 Vegan Capsule(s)
Servings per container
40
UPC/BARCODE
650786004350
IngredientAmount% DV
activated Coconut Charcoal735 mg--
Chlorella Algae126 mg--
Carob78.75 mg--
Shiitake Mushroom fruiting body extract68.25 mg--
Shilajit Resin Extract42 mg--

Other ingredients: Pullulan

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Seals/Symbols

TruGanic Verified Sourcing (Organic)

Certified Vegan Vegan.org

GF Certified Gluten-free

OU (Kosher) Pareve

Formulation

TruGanic Verified Sourcing (Organic)

Eco Facility

Vegan Ethics

Lab Verified Ecofresh Packaging

Charcoal Supreme is a detox and digestive support product. The foundation is activated coconut charcoal, a known absorbent agent. This is complemented by additional binders and GI tract supportive ingredients such as chlorella, carob, shiitake mushroom, and shilajit, which complete the robustness and efficiency of the binding capacity found in Charcoal Supreme. We proudly offer this unique formula as a supportive tool to assist the body's innate resiliency, especially during times of increased environmental stressors.

Adsorbent Detox Digestion

Certified Vegan Vegan.org

GF Certified Gluten-free

Organic TruGanic

Wildcrafted

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

General Statements

Curious to know more? Scan for full product information.

Formula

OU (Kosher) Pareve

Precautions

Contains Tree Nut (Coconut)

Suggested/Recommended/Usage/Directions

Suggested Use: Take 3 capsules per day with 8 oz of water (unchlorinated) at least 1 hour away from medications, or as advised by a qualified health care professional. Stay hydrated to ensure digestive regularity.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Charcoal Supreme by HealthForce SuperFoods label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Charcoal Supreme label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Charcoal Supreme by HealthForce SuperFoods

These are the 5 active ingredients this product is made of. Select any to open its full monograph.

Serving size3 Vegan Capsule(s) Dosage formCapsule Servings per container40 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Activated Coconut Charcoal

Interacts with
2,027 drugs
735 mg per serving

Activated charcoal is a highly porous form of carbon that can bind certain substances in the gut, and it is used in hospitals to treat some poisonings...

Activated Coconut Charcoal monograph & interactions

Chlorella Algae

Interacts with
337 drugs
126 mg per serving

Chlorella is a nutrient-rich freshwater green algae taken as a supplement for general wellness, immune support, and 'detox.' Some small studies sugges...

Chlorella Algae monograph & interactions

Carob

Interacts with
2,022 drugs
78.75 mg per serving

Carob is a Mediterranean tree whose pods are widely used as a caffeine-free, naturally sweet cocoa alternative and as a thickener (carob gum). It is m...

Carob monograph & interactions

Shiitake Mushroom fruiting body extract

Interacts with
312 drugs
68.25 mg per serving

Shiitake is a popular edible mushroom that is nutritious and safe to eat as food for most people. Some of its extracts (like lentinan and AHCC) have b...

Shiitake Mushroom fruiting body extract monograph & interactions

Shilajit Resin Extract

Interacts with
86 drugs
42 mg per serving

Shilajit is a sticky, tar-like substance found in rocks of mountain ranges like the Himalayas, used in traditional Ayurvedic medicine for energy and v...

Shilajit Resin Extract monograph & interactions

Other (inactive) ingredients: Pullulan. These complete the product’s ingredient list but are not active constituents.

Interaction report

Charcoal Supreme by HealthForce SuperFoods Drug Interactions

Want to check YOUR meds against Charcoal Supreme?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
2,163Drugs
2,022 Major 141 Moderate

Ingredients driving the most interactions

activated Coconut Charcoal 2,027
Carob 2,022
Chlorella Algae 337
Shiitake Mushroom fruiting body extract 312
Shilajit Resin Extract 86

Individual Drug Interactions

The ingredients in Charcoal Supreme interact with 2,163 drugs. Click any drug to see the details.

5 of the 5 ingredients in Charcoal Supreme interact with drugs. Each result below shows which ingredient is responsible. activated Coconut Charcoal Carob Chlorella Algae Shiitake Mushroom fruiting body extract Shilajit Resin Extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Charcoal Supreme with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

activated Coconut Charcoal3 drug types · 2,027 drugs

Oral Drugs

Activated charcoal reduces systemic exposure to many drugs, including those that undergo enterohepatic recirculation, regardless of the route of administration.
Activated charcoal adsorbs various drugs and may reduce their absorption and/or half-life. Examples of affected drugs include acetaminophen, aminophylline, amiodarone, atenolol, carbamazepine, dapsone, digoxin, disopyramide, fluoxetine, indomethacin, moxifloxacin, nadolol, phenytoin, phenobarbital, piroxicam, quinine, sotalol, theophylline, tricyclic antidepressants, valproate, and verapamil. Avoid co-administration, except after drug overdose.

Likelihood Probable Evidence B
Alcohol (Ethanol)

The binding action of activated charcoal may be reduced by alcohol.
Alcohol may lower the adsorptive capacity of activated charcoal.

Likelihood Probable Evidence D
Contraceptive Drugs

Activated charcoal may reduce the clinical effects of oral contraceptives.
Activated charcoal, taken in a dose of 5 grams four times daily for 3 days, may bind to, and reduce the absorption of, oral contraceptives, thereby limiting their effectiveness and increasing the risk of contraceptive failure. However, some clinical research shows that the risk for this interaction is minimal when activated charcoal is taken either 3 hours after or at least 12 hours before oral contraceptives.

Likelihood Possible Evidence B
activated Coconut Charcoal full monograph & interactions

Carob1 drug type · 2,022 drugs

Oral Drugs

Theoretically, carob might also impair the absorption of oral drugs.
Laboratory research shows that carob, when consumed as part of the diet or used as a thickening agent in infant formula, reduces the absorption of certain minerals. Take carob 30-60 minutes after oral medications.

Likelihood Possible Evidence D
Carob full monograph & interactions

Chlorella Algae2 drug types · 337 drugs

Photosensitizing Drugs

Theoretically, chlorella might have additive effects with photosensitizing drugs.
Chlorella has been reported to cause photosensitization. In five case reports, patients who had ingested chlorella exhibited swelling followed by erythematopurpuric lesions on sun-exposed areas of the body. Theoretically, concomitant use with photosensitizing drugs may exacerbate effects.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Theoretically, chlorella might reduce the clinical effects of warfarin.
Chlorella contains significant amounts of vitamin K. There is at least one case report of warfarin therapy becoming sub-therapeutic after initiation of chlorella supplements.

Likelihood Possible Evidence D
Chlorella Algae full monograph & interactions

Shiitake Mushroom fruiting body extract2 drug types · 312 drugs

Cytochrome P450 2D6 (Cyp2D6) Substrates

Theoretically, shiitake mushroom might decrease levels of drugs metabolized by CYP2D6.
In vitro studies suggest that the shiitake mushroom extract AHCC might induce the CYP2D6 enzyme. This effect has not been reported in humans.

Likelihood Possible Evidence D
Immunosuppressants

Theoretically, taking shiitake mushroom might decrease the effects of immunosuppressive therapy.
In vitro evidence suggests that shiitake mushroom extracts stimulate immune function.

Likelihood Possible Evidence D
Shiitake Mushroom fruiting body extract full monograph & interactions

Shilajit Resin Extract1 drug type · 86 drugs

Antidiabetes Drugs

Taking shilajit with antidiabetes drugs might increase the risk of hypoglycemia.
Most human and animal research shows that shilajit can decrease fasting plasma glucose levels. In an animal model, shilajit 100 mg per kg daily enhanced the glucose-lowering ability of both glibenclamide and metformin when given in combination over a 4 week period. Monitor blood glucose levels closely. Dose adjustments might be necessary.

Likelihood Possible Evidence D
Shilajit Resin Extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Charcoal Supreme, from the product label.

HealthForce SuperFoods

See all HealthForce SuperFoods products
Name
Excelsior Alchemy
City
Tempe
State
AZ
ZipCode
85284
Phone Number
(800) 748-6229
Web Address
www.HealthForceSuperFoods.com
Pharmacist Counseling Corner

Charcoal Supreme by HealthForce SuperFoods: Common Questions

Does Charcoal Supreme by HealthForce SuperFoods interact with any medications?
Yes. Based on its ingredients, Charcoal Supreme has a known interaction with 2,163 medications, including 2022 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Charcoal Supreme contains 5 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will this reduce how well my other medications work?
Yes — activated charcoal in this product binds to many oral drugs and can significantly reduce how much your body absorbs them. You must check your specific medications with the tool on this page or talk to your pharmacist before starting it.
Can I take this with birth control?
Activated charcoal may reduce how well oral contraceptives work, increasing the risk of contraceptive failure. Talk to your doctor or pharmacist about timing or an alternative birth control method if you want to use this product.
Is this safe in pregnancy?
Activated charcoal is possibly safe in pregnancy but isn't well studied for routine use — use only under medical guidance. Shilajit should be avoided in pregnancy due to lack of safety data and contamination risk. Talk with your doctor or pharmacist for personalized advice.
What are the most common side effects?
Activated charcoal most commonly causes constipation, black stools, bloating, abdominal pain, and gas. Chlorella may cause diarrhea, nausea, or fatigue, especially in the first two weeks. Shiitake can cause abdominal discomfort and nausea.
Does this actually work for detox or cleansing?
Activated charcoal is possibly effective for poisoning, but the evidence for detox, wound healing, hangover, or cleansing is insufficient to rate. The other ingredients also lack strong evidence for most claimed uses.
I take a diabetes medication — should I avoid this?
Shilajit in this product may lower blood sugar and could increase the risk of low blood sugar when combined with diabetes drugs. Talk to your doctor or pharmacist before starting it.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Charcoal Supreme is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Charcoal Supreme label
Go deeper

The Full Monographs Behind Charcoal Supreme’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Activated Charcoal

Interacts with 2,027 drugs

Activated charcoal is a highly porous form of carbon that can bind certain substances in the gut, and it is used in hospitals to treat some poisonings and overdoses. For everyday uses like g...

Read the full Activated Charcoal monograph → Herb & supplement monograph

Chlorella

Interacts with 337 drugs

Chlorella is a nutrient-rich freshwater green algae taken as a supplement for general wellness, immune support, and 'detox.' Some small studies suggest possible benefits for cholesterol, blo...

Read the full Chlorella monograph → Herb & supplement monograph

Carob

Interacts with 2,022 drugs

Carob is a Mediterranean tree whose pods are widely used as a caffeine-free, naturally sweet cocoa alternative and as a thickener (carob gum). It is mostly eaten as a food and is generally w...

Read the full Carob monograph → Herb & supplement monograph

Shiitake Mushroom

Interacts with 312 drugs

Shiitake is a popular edible mushroom that is nutritious and safe to eat as food for most people. Some of its extracts (like lentinan and AHCC) have been studied as immune support, mainly al...

Read the full Shiitake Mushroom monograph → Herb & supplement monograph

Shilajit

Interacts with 86 drugs

Shilajit is a sticky, tar-like substance found in rocks of mountain ranges like the Himalayas, used in traditional Ayurvedic medicine for energy and vitality. Human evidence is limited and m...

Read the full Shilajit monograph →
Sources

Sources & How We Checked

Charcoal Supreme's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 111 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Activated Charcoal 14 references
  1. Kaaja RJ, Kontula KK, Raiha A, Laatikainen T. Treatment of cholestasis of pregnancy with peroral activated charcoal. A preliminary study. Scand J Gastroenterol 1994;29:178-81.
  2. Anon. Position statement and practice guidelines on the use of multi-dose activated charcoal in the treatment of acute poisoning. American Academy of Clinical Toxicology; European Association of Poisons Centres and Clinical Toxicologists. J Toxicol Clin T
  3. Park GD, Spector R, Kitt TM. Superactivated charcoal versus cholestyramine for cholesterol lowering: a randomized cross-over trial. J Clin Pharmacol 1988;28:416-9. PubMed
  4. Hoegberg LC, Angelo HR, Christophersen AB, Christensen HR. Effect of ethanol and pH on the adsorption of acetaminophen (paracetamol) to high surface activated charcoal, in vitro studies. J Toxicol Clin Toxicol 2002;40:59-67. PubMed
  5. Brahmi N, Kouraichi N, Thabet H, Amamou M. Influence of activated charcoal on the pharmacokinetics and the clinical features of carbamazepine poisoning. Am J Emerg Med 2006;24(4):440-3. PubMed
  6. Gude AB, Hoegberg LC, Angelo HR, Christensen HR. Dose-dependent adsorptive capacity of activated charcoal for gastrointestinal decontamination of a simulated paracetamol overdose in human volunteers. Basic Clin Pharmacol Toxicol 2010;106(5)406-10. PubMed
  7. Wananukul W, Klaikleun S, Sriapha C, Tongpoo A. Effect of activated charcoal in reducing paracetamol absorption at supra-therapeutic dose. J Med Assoc Thai 2010;93(10):1145-9.
  8. Wang Z, Cui M, Tang L, et al. Oral activated charcoal suppresses hyperphosphataemia in haemodialysis patients. Nephrology (Carlton) 2012;17(7):616-20. PubMed
  9. Wang X, Mondal S, Wang J, et al. Effect of activated charcoal on apixaban pharmacokinetics in healthy subjects. Am J Cardiovasc Drugs 2014;14(2):147-54. PubMed
  10. Chyka PA, Seger D, Krenzelok EP, et al. Position paper: single-dose activated charcoal. Clin Toxicol (Phila) 2005;43(2):61-87. PubMed
  11. Chiew AL, Gluud C, Brok J, Buckley NA. Interventions for paracetamol (acetaminophen) overdose. Cochrane Database Syst Rev 2018;2:CD003328. PubMed
  12. Elomaa K, Ranta S, Tuominen J, Lähteenmäki P. Charcoal treatment and risk of escape ovulation in oral contraceptive users. Hum Reprod. 2001;16(1):76-81. PubMed
  13. Gao Y, Wang G, Li Y, Lv C, Wang Z. Effects of oral activated charcoal on hyperphosphatemia and vascular calcification in Chinese patients with stage 3-4 chronic kidney disease. J Nephrol. 2019;32(2):265-72. PubMed
  14. Skov K, Graudal NA, Jürgens G. The effect of activated charcoal on drug exposure following intravenous administration: A meta-analysis. Basic Clin Pharmacol Toxicol 2021;128(4):568-578. PubMed

See these in context on the Activated Charcoal monograph →

Chlorella 13 references
  1. Peirce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York, NY: William Morrow and Co., 1999.
  2. Ng TP, Tan WC, Lee YK. Occupational asthma in a pharmacist induced by chlorella, a unicellular algae preparation. Resp Med 1994;88:555-7. PubMed
  3. Jitsukawa K, Suizu R, Hidano A. Chlorella photosensitization. New phytophotodermatosis. Int J Dermatol 1984;23:263-8. PubMed
  4. Merchant RE, Carmack CA, Wise CM. Nutritional supplementation with Chlorella pyrenoidosa for patients with fibromyalgia syndrome: a pilot study. Phytother Res 2000;14:167-73.
  5. Merchant RE, Rice CD, Young HF. Dietary Chlorella pyrenoidosa for patients with malignant glioma: effects on immunocompetence, quality of life, and survival. Phytother Res 1990;4:220-31.
  6. Halperin SA, Smith B, Nolan C, et al. Safety and immunoenhancing effect of a Chlorella-derived dietary supplement in healthy adults undergoing influenza vaccination: randomized, double-blind, placebo-controlled trial. CMAJ 2003;169:111-7..
  7. Ohtake, T., Negishi, K., Okamoto, K., Oka, M., Maesato, K., Moriya, H., and Kobayashi, S. Manganese-induced Parkinsonism in a patient undergoing maintenance hemodialysis. Am J Kidney Dis 2005;46(4):749-753. PubMed
  8. Ng, T. P., Tan, W. C., and Lee, Y. K. Occupational asthma in a pharmacist induced by Chlorella, a unicellular algae preparation. Respir.Med. 1994;88(7):555-557. PubMed
  9. Ohkawa, S., Yoneda, Y., Ohsumi, Y., and Tabuchi, M. [Warfarin therapy and chlorella]. Rinsho Shinkeigaku 1995;35(7):806-807.
  10. Azocar J, Diaz A. Efficacy and safety of chlorella supplementation in adults with chronic hepatitis C virus infection. World J Gastroenterol 2013;19(7):1085-90. PubMed
  11. Panahi Y, Badeli R, Karami GR, Badeli Z, Sahebkar A. A randomized controlled trial of 6-week Chlorella vulgaris supplementation in patients with major depressive disorder. Complement Ther Med 2015;23(4):598-602. PubMed
  12. Nakano S, Takekoshi H, Nakano M. Chlorella pyrenoidosa supplementation reduces the risk of anemia, proteinuria and edema in pregnant women. Plant Foods Hum Nutr 2010;65(1):25-30. PubMed
  13. Yavasoglu I, Turgutkaya A, Bolaman Z. Chlorella-induced thrombocytopenia. Sao Paulo Med J 2018;136(6):602-3. PubMed

See these in context on the Chlorella monograph →

Carob 9 references
  1. Savino, F., Muratore, M. C., Silvestro, L., Oggero, R., and Mostert, M. Allergy to carob gum in an infant. J.Pediatr.Gastroenterol.Nutr. 1999;29(4):475-476. DOI
  2. Bosscher, D., Caillie-Bertrand, M., and Deelstra, H. Effect of thickening agents, based on soluble dietary fiber, on the availability of calcium, iron, and zinc from infant formulas. Nutrition 2001;17(7-8):614-618. PubMed
  3. van, der Brempt, X, Ledent, C., and Mairesse, M. Rhinitis and asthma caused by occupational exposure to carob bean flour. J.Allergy Clin.Immunol. 1992;90(6 Pt 1):1008-1010. PubMed
  4. Clarke, P. and Robinson, M. J. Thickening milk feeds may cause necrotising enterocolitis. Arch Dis.Child Fetal Neonatal Ed 2004;89(3):F280. PubMed
  5. Harmuth-Hoene, A. E. and Schelenz, R. Effect of dietary fiber on mineral absorption in growing rats. J Nutr 1980;110(9):1774-1784. PubMed
  6. Scoditti, A., Peluso, P., Pezzuto, R., Giordano, T., and Melica, A. Asthma to carob bean flour. Ann.Allergy Asthma Immunol. 1996;77(1):81. PubMed
  7. Komericki P, Kränke B. Immediate hypersensitivity to carob pods. Contact Dermatitis. 2009;61(4):239-40. PubMed
  8. Bosscher D, Van Caillie-Bertrand M, Van Cauwenbergh R, Deelstra H. Availabilities of calcium, iron, and zinc from dairy infant formulas is affected by soluble dietary fibers and modified starch fractions. Nutrition. 2003;19(7-8):641-5. PubMed
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Shiitake Mushroom 67 references
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Shilajit 8 references
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