Interactions on record — worth a quick check against your medications. Based on 3 of 4 ingredients. Check your meds →
Dietary supplement

Chris Kilham's Vital Immunity Ingredients & Drug Interactions

by Purity Products

Chris Kilham's Vital Immunity label
See full label image
Tablet Or Pill Category: Botanical With Nutrients
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Chris Kilham's Vital Immunity against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Chris Kilham's Vital Immunity is a dietary supplement by Purity Products with 4 active ingredients. Its ingredients are commonly taken for common cold and immune support, antioxidant support, skin health and collagen formation.Based on those ingredients, 1,429 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are organic KSM-66 Ashwagandha extract, Vitamin C, Elderberry. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Chris Kilham's Vital Immunity by Purity Products

Ask about any prescription or over-the-counter medication and we check it for interactions with Chris Kilham's Vital Immunity by Purity Products — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Chris Kilham's Vital Immunity by Purity Products

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 12, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 4 of its 4 active ingredients.
  • “BerryShield European Elderberry Concentrate” is listed as a grouped ingredient — the label gives one combined amount (500 mg) without saying how much of each component you get.

Chris Kilham's Vital Immunity contains four active ingredients. Elderberry is the main immune-supporting herb in the formula (delivered as BerryShield European Elderberry Concentrate).

Vitamin C supports immune function and acts as an antioxidant. Ashwagandha (organic KSM-66 extract) is an adaptogenic herb traditionally used for stress and sleep support.

Prebiotic fiber feeds beneficial gut bacteria. The tablet also contains several inactive ingredients — corn fiber, microcrystalline cellulose, potato starch, and others — that serve as binders and flow agents.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: Promotes healthy immune system response and stress management.
  • We looked for evidence on: Anxiety, Acute bronchitis, Asthma, Bronchitis, Chronic obstructive pulmonary disease (COPD), Coronavirus disease 2019 (COVID-19) — and 4 related terms.
  • The strongest evidence on file: Ashwagandha is rated "Possibly Effective" for Anxiety (Natural Medicines).
  • Also on file: Ashwagandha is rated "Possibly Effective" for Generalized anxiety disorder (GAD).
  • Also on file: Vitamin C is rated "Possibly Effective" for Exercise-induced respiratory infections.

For elderberry alone, the evidence we hold rates it as having insufficient reliable evidence for respiratory tract infections, allergies, cardiovascular disease, fatigue, lung disease, and thinking/memory. Vitamin C is effective for preventing vitamin C deficiency and is possibly effective for anemia, atrial fibrillation, cataracts, and exercise-related respiratory infections.

Ashwagandha is possibly effective for insomnia, anxiety, stress, and generalized anxiety disorder, though evidence for bipolar disorder is insufficient. No overall effectiveness rating for the full product combination is provided in the data we hold.

The evidence, ingredient by ingredient Vitamin C Ashwagandha Elderberry

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 3 of the 3 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 3 of 3.
  • General safety write-ups exist for 3 of 3.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Properly prepared (cooked) elderberry products are generally well tolerated. Raw or unripe elderberries, along with the seeds, leaves, and bark, can contain toxins that cause nausea, vomiting, severe diarrhea, weakness, dizziness, and numbness — cooking eliminates this risk.

Vitamin C is generally well tolerated at normal doses, but very high doses (above 2 grams daily) may cause abdominal cramps, heartburn, diarrhea, nausea, and kidney stones in susceptible people. Ashwagandha seems well tolerated in the short term, though long-term safety data are limited.

Common side effects from ashwagandha are mild and include diarrhea, stomach upset, nausea, and vomiting, but these don't occur often at typical doses. Rare case reports have linked ashwagandha to liver problems.

During pregnancy, elderberry safety data are insufficient, so it's best to avoid it; the same applies to ashwagandha, which has traditionally been thought to risk miscarriage. Vitamin C at normal prenatal amounts is fine, but high-dose supplements should be avoided in pregnancy without medical guidance.

For breastfeeding, elderberry and ashwagandha lack sufficient safety information, so avoidance is advised; normal vitamin C amounts are considered safe, but high-dose supplements should be directed by a healthcare provider.

Side effects, ingredient by ingredient Vitamin C Ashwagandha Elderberry

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 3 of the 3 matched ingredients can interact with medications — Elderberry, Ashwagandha, Vitamin C.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; immunosuppressants / transplant drugs; cancer treatments; diabetes medications.
  • For scale: 1,430 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take this product, check if you're on immunosuppressants (both elderberry and ashwagandha can interfere with them), benzodiazepines or other sedatives (ashwagandha may increase drowsiness), antihypertensive drugs (ashwagandha may lower blood pressure further), warfarin or other blood thinners (vitamin C at high doses may reduce their effectiveness), diabetes medications (ashwagandha may increase low blood sugar risk), thyroid hormone replacement (ashwagandha may boost its effects), or estrogen-based hormones like birth control pills (vitamin C may increase estrogen levels). There's also a theoretical concern that vitamin C could reduce the effectiveness of certain chemotherapy drugs.

Use the medication checker on this page to see if any of your drugs are listed.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This product may be worth considering if you're looking for immune support with adaptogenic (stress-relieving) benefits and you don't take prescription medications that interact with its ingredients. If you're on immunosuppressants, blood thinners, diabetes drugs, blood pressure medications, or hormonal contraceptives, you should check your specific medications with the tool on this page before starting.

Pregnant or breastfeeding individuals should talk with their pharmacist or doctor before using it. Anyone with liver disease or a history of liver problems should discuss ashwagandha specifically with their healthcare provider.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 3 of 4 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jan 22, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Chris Kilham's Vital Immunity, straight from the product label.

Brand Purity Products
Net contents 60 Tablet(s)
Market status On market
Date entered into DSLD Jan 22, 2021
DSLD ID 243485
Product type Botanical With Nutrients
Supplement form Tablet Or Pill
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), No Allergies
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Chris Kilham's Vital Immunity by Purity Products, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Tablet(s)
Maximum serving Sizes:
2 Tablet(s)
Servings per container
30
IngredientAmount% DV
Elderberry210 mg--
Prebiotic Fiber290 mg--
Vitamin C500 mg556%
organic KSM-66 Ashwagandha extract600 mg--
BerryShield European Elderberry Concentrate500 mg--

Other ingredients: Corn fiber, Microcrystalline Cellulose, Potato Starch, Stearic Acid, Dicalcium Phosphate, Croscarmellose Sodium, Vegetable Magnesium Stearate, Silicon Dioxide, SlipTech Clean Finish

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Intelligent nutritional solutions

Chris Kilham Medicine Hunter

Premium grade supplements Since 1993

Formula

500mg BerryShield Elderberry 500mg PureWay-C vitamin C 600mg KSM-66 Ashwagandha

Pure Way Antioxidant super nutrient

Formulation

Promotes healthy immune system response Supports healthy stress management

Allergen free

Non GMO

Vegan

Suggested/Recommended/Usage/Directions

Suggested Use: Adults take 2 tablets daily. For daily use.

Brand IP Statement(s)

PureWay-C is a trademark of One Innovation Labs, LLC. KSM-66 is registered trademark of IXOREAL BIOMED. BerryShield is a registered trademark of NutriScience Innovations LLC.

Seals/Symbols

Made in a GMP Certified Facility Lab tested in the USA

FDA Statement of Identity

Dietary Supplement

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Chris Kilham's Vital Immunity by Purity Products label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Chris Kilham's Vital Immunity label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Chris Kilham's Vital Immunity by Purity Products

These are the 4 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 Tablet(s) Dosage formTablet Or Pill Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Vitamin C

Interacts with
207 drugs
500 mg per serving Form: Pureway-C

Vitamin C (ascorbic acid) is an essential nutrient your body needs but cannot make, so you must get it from food or supplements. It's important for im...

Vitamin C monograph & interactions

Organic KSM-66 Ashwagandha extract

Interacts with
1,372 drugs
600 mg per serving

Ashwagandha is an Ayurvedic herb most often taken to help with stress, anxiety, and sleep, and some small studies suggest it may help, though the evid...

Organic KSM-66 Ashwagandha extract monograph & interactions

BerryShield European Elderberry Concentrate

500 mg per serving

Other (inactive) ingredients: Corn fiber, Microcrystalline Cellulose, Potato Starch, Stearic Acid, Dicalcium Phosphate, Croscarmellose Sodium, Vegetable Magnesium Stearate, Silicon Dioxide, SlipTech Clean Finish. These complete the product’s ingredient list but are not active constituents.

Interaction report

Chris Kilham's Vital Immunity by Purity Products Drug Interactions

Want to check YOUR meds against Chris Kilham's Vital Immunity?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
1,429Drugs
989 Moderate 440 Minor

Ingredients driving the most interactions

organic KSM-66 Ashwagandha extract 1,372
Vitamin C 207
Elderberry 121

Individual Drug Interactions

The ingredients in Chris Kilham's Vital Immunity interact with 1,429 drugs. Click any drug to see the details.

3 of the 4 ingredients in Chris Kilham's Vital Immunity interact with drugs. Each result below shows which ingredient is responsible. organic KSM-66 Ashwagandha extract Vitamin C Elderberry

Each ingredient & the kinds of drugs it affects

For each ingredient in Chris Kilham's Vital Immunity with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

organic KSM-66 Ashwagandha extract10 drug types · 1,372 drugs

Antidiabetes Drugs

Theoretically, taking ashwagandha with antidiabetes drugs might increase the risk of hypoglycemia.
There is preliminary clinical evidence suggesting that ashwagandha might lower blood glucose levels. Theoretically, ashwagandha might have additive effects when used with antidiabetes drugs and increase the risk of hypoglycemia.

Likelihood Possible Evidence B
Antihypertensive Drugs

Theoretically, taking ashwagandha with antihypertensive drugs might increase the risk of hypotension.
Animal research suggests that ashwagandha might lower systolic and diastolic blood pressure. Theoretically, ashwagandha might have additive effects when used with antihypertensive drugs and increase the risk of hypotension.

Likelihood Possible Evidence D
Benzodiazepines

Theoretically, taking ashwagandha might increase the sedative effects of benzodiazepines.
There is preliminary evidence that ashwagandha might have an additive effect with diazepam (Valium) and clonazepam (Klonopin). This may also occur with other benzodiazepines.

Likelihood Possible Evidence D
Cns Depressants

Theoretically, taking ashwagandha might increase the sedative effects of CNS depressants.
Ashwagandha seems to have sedative effects. Theoretically, this may potentiate the effects of barbiturates, other sedatives, and anxiolytics.

Likelihood Possible Evidence D
Hepatotoxic Drugs

Theoretically, taking ashwagandha with hepatotoxic drugs might increase the risk of liver damage.
Ashwagandha has been linked to cases of acute hepatitis, liver failure, hepatic encephalopathy, autoimmune hepatitis, the need for liver transplantation, and death due to liver failure.

Likelihood Possible Evidence D
Immunosuppressants

Theoretically, taking ashwagandha might decrease the effects of immunosuppressants.
Ashwagandha has demonstrated immunostimulant effects in humans. Animal research has shown that ashwagandha can attenuate the immunosuppression caused by cyclophosphamide.

Likelihood Possible Evidence D
Thyroid Hormone

Ashwagandha might increase the effects and adverse effects of thyroid hormone.
Concomitant use of ashwagandha with thyroid hormones may cause additive therapeutic and adverse effects. Preliminary clinical research and animal studies suggest that ashwagandha boosts thyroid hormone synthesis and secretion. In one clinical study, ashwagandha increased triiodothyronine (T3) and thyroxine (T4) levels by 41.5% and 19.6%, respectively, and reduced serum TSH levels by 17.4% from baseline in adults with subclinical hypothyroidism.

Likelihood Probable Evidence B
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, ashwagandha might decrease the levels and clinical effects of CYP1A2 substrates.
In vitro research shows that ashwagandha extract induces CYP1A2 enzymes.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, ashwagandha might decrease the levels and clinical effects of CYP3A4 substrates.
In vitro research shows that ashwagandha extract induces CYP3A4 enzymes.

Likelihood Possible Evidence D
Serotonergic Drugs

Some animal studies have reported that ashwagandha can enhance serotonergic transmission by altering certain serotonin (5-HT) receptors. However, there is no evidence to suggest that ashwagandha increases the risk of serotonin-related effects, and there have been no published case reports of serotonin syndrome when combined with other serotonergic drugs. Nevertheless, due to the lack of extensive studies on the matter and the fact that ashwagandha appears to affect serotonergic pathways, it would be prudent to exercise caution when combining it with drugs that affect serotonin. [References: - Effects of Withania somnifera (Ashwaga ndha) on Stress and the Stress-Related Neuropsychiatric Disorders Anxiety, Depression, and Insomnia. Curr Neuropharmacol. 2021 Sep 14; 19: 1468–1495. - A Prospective, Randomized Double-Blind, Placebo-Controlled Study of Safety and Efficacy of a High-Concentration Full-Spectrum Extract of Ashwagandha Root in Reducing Stress and Anxiety in Adults. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3573577/]

Likelihood Possible Evidence C
organic KSM-66 Ashwagandha extract full monograph & interactions

Vitamin C13 drug types · 207 drugs

Alkylating Agents

Theoretically, antioxidant effects of vitamin C might reduce the effectiveness of alkylating agents.
The use of antioxidants like vitamin C during chemotherapy is controversial. There is concern that antioxidants could reduce the activity of chemotherapy drugs that generate free radicals, such as cyclophosphamide, chlorambucil, carmustine, busulfan, and thiotepa. In contrast, some researchers theorize that antioxidants might make chemotherapy more effective by reducing oxidative stress that could interfere with apoptosis (cell death) of cancer cells. More evidence is needed to determine what effect, if any, antioxidants such as vitamin C have on chemotherapy.

Likelihood Possible Evidence D
Aluminum

Vitamin C can increase the amount of aluminum absorbed from aluminum compounds.
Research in animals and humans shows that vitamin C increases aluminum absorption, theoretically by chelating aluminum and keeping it in solution where it is available for absorption. In people with normal renal function, urinary excretion of aluminum will likely increase, making aluminum retention and toxicity unlikely. Patients with renal failure who take aluminum-containing compounds such as phosphate binders should avoid vitamin C supplements in doses above the recommended dietary allowances.

Likelihood Probable Evidence B
Antitumor Antibiotics

Theoretically, the antioxidant effects of vitamin C might reduce the effectiveness of antitumor antibiotics.
The use of antioxidants like vitamin C during chemotherapy is controversial. There is concern that antioxidants could reduce the activity of chemotherapy drugs which generate free radicals, such as doxorubicin. In contrast, some researchers theorize that antioxidants might make chemotherapy more effective by reducing oxidative stress that could interfere with apoptosis (cell death) of cancer cells. More evidence is needed to determine what effects, if any, antioxidants such as vitamin C have on chemotherapy.

Likelihood Possible Evidence D
Estrogens

Vitamin C might increase blood levels of estrogens.
Increases in plasma estrogen levels of up to 55% occur under some circumstances when vitamin C is taken concurrently with oral contraceptives or hormone replacement therapy, including topical products. It is suggested that vitamin C prevents oxidation of estrogen in the tissues, regenerates oxidized estrogen, and reduces sulfate conjugation of estrogen in the gut wall. When tissue levels of vitamin C are high, these processes are already maximized and supplemental vitamin C does not have any effect on estrogen levels. Increases in plasma estrogen levels may occur when patients who are deficient in vitamin C take supplements. Monitor these patients for estrogen-related side effects.

Likelihood Probable Evidence B
Fluphenazine (Prolixin)

Theoretically, vitamin C might decrease levels of fluphenazine.
In one patient there was a clinically significant decrease in fluphenazine levels when vitamin C (500 mg twice daily) was started. The mechanism is not known, and there is no further data to confirm this interaction.

Likelihood Possible Evidence D
Indinavir (Crixivan)

Vitamin C can modestly reduce indinavir levels.
One pharmacokinetic study shows that taking vitamin C 1 gram orally once daily along with indinavir 800 mg orally three times daily reduces the area under the concentration-time curve of indinavir by 14%. The mechanism of this interaction is unknown, but it is unlikely to be clinically significant in most patients. The effect of higher doses of vitamin C on indinavir levels is unknown.

Likelihood Probable Evidence B
Levothyroxine (Synthroid, Others)

Vitamin C can increase levothyroxine absorption.
Two clinical studies in adults with poorly controlled hypothyroidism show that swallowing levothyroxine with a glass of water containing vitamin C 500-1000 mg in solution reduces thyroid stimulating hormone (TSH) levels and increases thyroxine (T4) levels when compared with taking levothyroxine alone. This suggests that vitamin C increases the oral absorption of levothyroxine, possibly due to a reduction in pH.

Likelihood Probable Evidence B
Warfarin (Coumadin)

High-dose vitamin C might reduce the levels and effectiveness of warfarin.
Vitamin C in high doses may cause diarrhea and possibly reduce warfarin absorption. There are reports of two people who took up to 16 grams daily of vitamin C and had a reduction in prothrombin time. Lower doses of 5-10 grams daily can also reduce warfarin absorption. In many cases, this does not seem to be clinically significant. However, a case of warfarin resistance has been reported for a patient who took vitamin C 500 mg twice daily. Cessation of vitamin C supplementation resulted in a rapid increase in international normalized ratio (INR). Tell patients taking warfarin to avoid taking vitamin C in excessively high doses (greater than 10 grams daily). Lower doses may be safe, but the anticoagulation activity of warfarin should be monitored. Patients who are stabilized on warfarin while taking vitamin C should avoid adjusting vitamin C dosage to prevent the possibility of warfarin resistance.

Likelihood Possible Evidence D
Acetaminophen (Tylenol, Others)

High-dose vitamin C might slightly prolong the clearance of acetaminophen.
A small pharmacokinetic study in healthy volunteers shows that taking high-dose vitamin C (3 grams) 1.5 hours after taking acetaminophen 1 gram slightly increases the apparent half-life of acetaminophen from around 2.3 hours to 3.1 hours. Ascorbic acid competitively inhibits sulfate conjugation of acetaminophen. However, to compensate, elimination of acetaminophen glucuronide and unconjugated acetaminophen increases. This effect is not likely to be clinically significant.

Likelihood Probable Evidence B
Aspirin

Acidification of the urine by vitamin C might increase aspirin levels.
It has been suggested that acidification of the urine by vitamin C could increase reabsorption of salicylates by the renal tubules, and increase plasma salicylate levels. However, short-term use of up to 6 grams daily of vitamin C does not seem to affect urinary pH or salicylate excretion, suggesting this interaction is not clinically significant.

Likelihood Possible Evidence B
Choline Magnesium Trisalicylate (Trilisate)

Acidification of the urine by vitamin C might increase choline magnesium trisalicylate levels.
It has been suggested that acidification of the urine by vitamin C could increase reabsorption of salicylates by the renal tubules, and increase plasma salicylate levels. However, short-term use of up to 6 grams daily of vitamin C does not seem to affect urinary pH or salicylate excretion, suggesting this interaction probably is not clinically significant.

Likelihood Possible Evidence B
Niacin

Vitamin C might decrease the beneficial effects of niacin on high-density lipoprotein (HDL) cholesterol levels.
A combination of niacin and simvastatin (Zocor) effectively raises HDL cholesterol levels in patients with coronary disease and low HDL levels. Clinical research shows that taking a combination of antioxidants (vitamin C, vitamin E, beta-carotene, and selenium) along with niacin and simvastatin (Zocor) attenuates this rise in HDL, specifically the HDL-2 and apolipoprotein A1 fractions, by more than 50% in patients with coronary disease. It is not known whether this adverse effect is due to a single antioxidant such as vitamin C, or to the combination. It also is not known whether it will occur in other patient populations.

Likelihood Possible Evidence A
Salsalate (Disalcid)

Acidification of the urine by vitamin C might increase salsalate levels.
It has been suggested that acidification of the urine by vitamin C could increase reabsorption of salicylates by the renal tubules, and increase plasma salicylate levels. However, short-term use of up to 6 grams/day vitamin C does not seem to affect urinary pH or salicylate excretion, suggesting this interaction probably is not clinically significant.

Likelihood Possible Evidence B
Vitamin C full monograph & interactions

Elderberry2 drug types · 121 drugs

Immunosuppressants

Theoretically, elderberry might interfere with immunosuppressant therapy due to its immunostimulant activity.
Elderberry has immunostimulant activity, increasing the production of cytokines, including interleukin and tumor necrosis factor.

Likelihood Possible Evidence B
Pazopanib (Votrient)

Theoretically, elderberry might interact with pazopanib, potentially increasing the risk of adverse effects.
In one case, a 65-year-old patient taking pazopanib for 4 weeks for soft-tissue sarcoma developed severe nausea, loose stools, and elevated alanine transaminase and aspartate transaminase levels and was diagnosed with grade 3 liver injury. The patient reported taking elderberry supplements for 2 years, dose unspecified, and was also taking a multivitamin and a calcium supplement. The patient's symptoms and liver enzyme levels improved upon discontinuation of pazopanib and all supplements. Pazopanib treatment was re-initiated, at a lower dose, with no further evidence of liver injury. It was unclear in this case report if the elderberry supplements were derived from the berry, the flower, or the combination.

Likelihood Possible Evidence D
Elderberry full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Chris Kilham's Vital Immunity, from the product label.

Purity Products

See all Purity Products products
Name
Purity Products
Pharmacist Counseling Corner

Chris Kilham's Vital Immunity by Purity Products: Common Questions

Does Chris Kilham's Vital Immunity by Purity Products interact with any medications?
Yes. Based on its ingredients, Chris Kilham's Vital Immunity has a known interaction with 1,429 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Chris Kilham's Vital Immunity contains 4 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is this safe to take if I'm pregnant?
Elderberry and ashwagandha lack enough safety data in pregnancy, so it's best to avoid them. Vitamin C at normal prenatal amounts is fine, but high-dose supplements should not be taken without medical approval. Talk with your doctor or pharmacist before using this product during pregnancy.
Will this help me avoid getting sick?
Elderberry doesn't have enough reliable evidence to support its use for preventing colds or other respiratory infections. The evidence we hold for the other ingredients in this formula doesn't directly address preventing illness, so we can't confirm whether this product will help you avoid getting sick.
What does ashwagandha in this product do?
Ashwagandha is possibly effective for insomnia, anxiety, stress, and generalized anxiety disorder. It's an adaptogenic herb, meaning it may help your body manage stress. The product includes the KSM-66 extract, which is a standardized form of ashwagandha root.
Is vitamin C in this product safe at this dose?
The facts don't specify how much vitamin C is in each tablet, so we can't tell you whether the dose is safe. Vitamin C is generally well tolerated, but very high doses above 2 grams daily can cause stomach upset, diarrhea, and kidney stones in susceptible people. Check the label and compare it to the tolerable upper intake level of 2 grams daily, or ask your pharmacist.
Can I take this if I'm on birth control pills?
Vitamin C in this product may increase estrogen levels, which could theoretically affect how your birth control works. Check with your pharmacist about your specific dose and your pill type before starting.
Does this product contain any fillers?
Yes, it contains several inactive ingredients used as binders and flow agents, including corn fiber, microcrystalline cellulose, potato starch, stearic acid, and others. These are typical excipients that help hold the tablet together and don't add active benefit.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Chris Kilham's Vital Immunity label
Go deeper

The Full Monographs Behind Chris Kilham's Vital Immunity’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Vitamin C

Interacts with 207 drugs

Vitamin C (ascorbic acid) is an essential nutrient your body needs but cannot make, so you must get it from food or supplements. It's important for immune function, collagen, and acts as an...

Read the full Vitamin C monograph → Herb & supplement monograph

Ashwagandha

Interacts with 1,372 drugs

Ashwagandha is an Ayurvedic herb most often taken to help with stress, anxiety, and sleep, and some small studies suggest it may help, though the evidence is still limited. It is generally w...

Read the full Ashwagandha monograph → Herb & supplement monograph

Elderberry

Interacts with 121 drugs

Elderberry is a popular herbal supplement, mainly taken to help with colds and flu. Some small studies suggest it may modestly shorten cold or flu symptoms, but the evidence is limited and n...

Read the full Elderberry monograph →
Sources

Sources & How We Checked

Chris Kilham's Vital Immunity's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 89 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Elderberry 6 references
  1. Barak V, Halperin T, Kalickman I. The effect of Sambucol, a black elderberry-based, natural product, on the production of human cytokines: I. Inflammatory cytokines. Eur Cytokine Netw 2001;12:290-6..
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Ashwagandha 32 references
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