CitraNatal Assure DHA Soft Gel Ingredients & Drug Interactions
by Mission Pharmacal CitraNatal
What is this page for?
First and foremost: checking CitraNatal Assure DHA Soft Gel against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
CitraNatal Assure DHA Soft Gel is a dietary supplement by Mission Pharmacal CitraNatal with 1 active ingredient. Its ingredients are commonly taken for vegan/vegetarian source of omega-3s (dha and epa), heart and triglyceride health, brain and eye support.Based on those ingredients, 375 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Algal Oil. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against CitraNatal Assure DHA Soft Gel by Mission Pharmacal CitraNatal
Ask about any prescription or over-the-counter medication and we check it for interactions with CitraNatal Assure DHA Soft Gel by Mission Pharmacal CitraNatal — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of CitraNatal Assure DHA Soft Gel by Mission Pharmacal CitraNatal
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains one active ingredient: algal oil, a source of docosahexaenoic acid (DHA), an omega-3 fatty acid that supports brain and eye development. The soft gel is made with inactive ingredients including gelatin, glycerin, sunflower oil, water, caramel color, and preservatives (tocopherols and rosemary extract).
Does it work?
Moderate evidence
The evidence we hold shows algal oil is possibly effective for reducing the risk of preterm labor. For other uses — fractures, cystic fibrosis, physical performance, and cognitive function — the data suggests it's possibly ineffective.
For nonalcoholic fatty liver disease (NAFLD), there isn't enough reliable evidence yet to say whether it works.
How safe is it?
Well-documented data
Algal oil is generally well tolerated by most healthy adults at typical supplement doses. One person reported increased hair loss after completing a course of algal oil with DHA, though it's unclear if the supplement caused it.
Theoretically, DHA may raise LDL cholesterol ('bad' cholesterol) by a small amount, and there's preliminary research suggesting higher DHA intake *might* be linked to prostate cancer risk — but more study is needed, and this hasn't been confirmed in people taking the supplement. DHA is often recommended in pregnancy and supports infant development, but use only under the guidance of your doctor or pharmacist, especially during breastfeeding.
Meds to double-check
Moderate interaction found
Before taking CitraNatal Assure DHA, check with your doctor or pharmacist if you take antihypertensive drugs (blood pressure medications) — algal oil may lower your blood pressure further. Also double-check if you're on antidiabetes drugs (blood sugar medications) or anticoagulant/antiplatelet drugs (blood thinners) — both carry documented risks with algal oil.
The bottom line
Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
This product is designed to deliver DHA for pregnancy and early infant development, and the evidence supports its use for lowering preterm labor risk. If you take blood pressure medications, blood sugar medications, or blood thinners, check with your doctor or pharmacist first — algal oil may interact with them.
The same goes if you're concerned about cholesterol or prostate health. Talk it over with your own healthcare provider to make sure it fits your situation.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Dec 14, 2023.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about CitraNatal Assure DHA Soft Gel, straight from the product label.
| Brand | Mission Pharmacal CitraNatal |
|---|---|
| Barcode (UPC) | 301780891308 |
| Net contents | 6 5-day Blister Pack(s) |
| Market status | On market |
| Date entered into DSLD | Dec 14, 2023 |
| DSLD ID | 304787 |
| Product type | Fat/fatty Acid |
| Supplement form | Other (e.g. Tea Bag) |
| Dietary claims / uses | Nutrient, All Other, Structure/Function |
| Intended target group(s) | Pregnant Women, Adult Female (18 - 50 Years), Lactating |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for CitraNatal Assure DHA Soft Gel by Mission Pharmacal CitraNatal, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Docosahexaenoic Acid | 300 mg | -- |
| Algal Oil | 750 mg | -- |
Other ingredients: Gelatin, Glycerin, high Oleic Sunflower Oil, Water, Caramel color, Tocopherols, Rosemary Extract, Ascorbyl Palmitate
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation
When you Want Complete Care Quality ingredients, true comfort: Stool softener
Formula
35 mg Ferr-Ease dual-iron 300 mg DHA 124 mg Calcium (calcium citrate)
Description: CitraNatal Assure is a prescription prenatal/postnatal multi-vitamin/mineral tablet with Ferr-Ease, a dual-iron delivery comprising both a quick release and slow release iron, and a soft gel of DHA, an essential fatty acid. The essential fatty acid DHA soft gel is oblong, transparent, and caramel colored.
Indications: CitraNatal Assure is a multi-vitamin/mineral prescription drug indicated for use in improving the nutritional status of women prior to conception, throughout pregnancy, and in the postnatal period for both lactating and nonlactating mothers.
Ferr-Ease Dual-iron delivery
General Statements
Please see side of carton for other important ingredients. Rx Only
How Supplied: Six children-resistant blister packs of 5 tablets and 5 soft gels each - NDC 0178-0891-30.
Precautions
Six 5-Day Blister Packs in Child-Resistant Packaging
Contraindications: This product is contraindicated in patients with a known hypersensitivity to any of the ingredients.
Warning: Accidental overdose of iron-containing products is a leading cause of fatal poisoning in children under 6. Keep this product out of the reach of children. In case of accidental overdose, call a doctor or poison control center immediately.
Warning: Ingestion of more than 3 grams of omega-3 fatty acids per day has been shown to have potential antithrombotic effects, including an increased bleeding time and INR.
Administration of omega-3 fatty acids should be avoided in patients on anticoagulants and in those known to have an inherited or acquired bleeding diathesis.
Warning: Folic acid alone is improper therapy in the treatment of pernicious anemia and other megaloblastic anemias where vitamin B12 is deficient. Precautions: Folic acid in doses above 0.1 mg daily may obscure pernicious anemia in that hematologic remission can occur while neurological manifestations progress.
Adverse Reactions: Allergic sensitization has been reported following both oral and parenteral administration of folic acid.
Caution: Exercise caution to ensure that the prescribed dosage of DHA does not exceed 1 gram (1000 mg) per day.
To report a serious adverse event or obtain product information, call (800) 298-1087. Please consult your health care provider with any dietary concerns.
Suggested/Recommended/Usage/Directions
Dosage and Administration: One tablet and one soft gel daily or as directed by a physician.
Storage
Storage: Store at 20 degrees C to 25 degrees C (68 degrees F to 77 degrees F), excursions permitted between 15 degrees C and 30 degrees C (between 59 degrees F and 86 degrees F). Brief exposure to temperatures up to 40 degrees C (104 degrees F) may be tolerated provided the mean kinetic temperature does not exceed 25 degrees C (77 degrees F); however, such exposure should be minimized.
Notice: Contact with moisture can discolor or erode the tablet.
Brand IP Statement(s)
Ferr-Ease Dual-iron delivery Trademark of Mission Pharmacal Company Copyright 2020 Mission Pharmacal Company. All rights reserved.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
CitraNatal Assure DHA Soft Gel by Mission Pharmacal CitraNatal label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in CitraNatal Assure DHA Soft Gel by Mission Pharmacal CitraNatal
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 Softgel(s) Dosage formOther (e.g. Tea Bag) Servings per container30 Amounts shown are per serving.
Docosahexaenoic Acid
Other (inactive) ingredients: Gelatin, Glycerin, High Oleic Sunflower Oil, Water, Caramel color, Tocopherols, Rosemary Extract, Ascorbyl Palmitate. These complete the product’s ingredient list but are not active constituents.
CitraNatal Assure DHA Soft Gel by Mission Pharmacal CitraNatal Drug Interactions
HelloPharmacist Interaction Report
CitraNatal Assure DHA Soft Gel contains algal oil, which is documented to interact with three medication types.
The most serious is antihypertensive drugs (blood pressure medications): algal oil may lower blood pressure further, raising the risk of excessively low blood pressure (hypotension). This is a Moderate-severity interaction.
Read the full breakdown — every affected drug type, severity by severity
You'll also want to check if you take antidiabetes drugs (medications for blood sugar control). Algal oil may theoretically interfere with how well these drugs work, which is also rated Moderate.
Additionally, if you're on anticoagulant or antiplatelet drugs (blood thinners or anti-clotting medications), algal oil carries a Minor risk of increased bleeding, especially at higher doses.
Algal oil is the only active ingredient in this product that we have interaction data for. Altogether, these interactions span 375 individual medications.
Before you start this supplement, run your exact medications through the interaction checker on this page to see if any of yours are affected.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against CitraNatal Assure DHA Soft Gel?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in CitraNatal Assure DHA Soft Gel interact with 375 drugs. Click any drug to see the details.
1 of the 1 ingredient in CitraNatal Assure DHA Soft Gel interact with drugs. Each result below shows which ingredient is responsible. Algal Oil
AcarboseGlucobay, Prandase, Precose
How Acarbose interacts with CitraNatal Assure DHA Soft Gel — through 1 ingredient. Tap an ingredient for the detail:
Algal OilAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking algal oil with antidiabetes drugs might interfere with the effects of antidiabetes drugs and reduce their effects.
Read the full Algal Oil + Acarbose interactionAcebutololRhotral, Sectral
How Acebutolol interacts with CitraNatal Assure DHA Soft Gel — through 1 ingredient. Tap an ingredient for the detail:
Algal OilAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking algal oil with antihypertensive drugs might increase the risk of hypotension.
Read the full Algal Oil + Acebutolol interactionAcetazolamideAk-Zol, Diamox
How Acetazolamide interacts with CitraNatal Assure DHA Soft Gel — through 1 ingredient. Tap an ingredient for the detail:
Algal OilAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking algal oil with antihypertensive drugs might increase the risk of hypotension.
Read the full Algal Oil + Acetazolamide interactionAcetohexamideDymelor
How Acetohexamide interacts with CitraNatal Assure DHA Soft Gel — through 1 ingredient. Tap an ingredient for the detail:
Algal OilAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking algal oil with antidiabetes drugs might interfere with the effects of antidiabetes drugs and reduce their effects.
Read the full Algal Oil + Acetohexamide interactionAlbiglutideTanzeum
How Albiglutide interacts with CitraNatal Assure DHA Soft Gel — through 1 ingredient. Tap an ingredient for the detail:
Algal OilAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking algal oil with antidiabetes drugs might interfere with the effects of antidiabetes drugs and reduce their effects.
Read the full Algal Oil + Albiglutide interactionAliskirenTekturna
How Aliskiren interacts with CitraNatal Assure DHA Soft Gel — through 1 ingredient. Tap an ingredient for the detail:
Algal OilAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking algal oil with antihypertensive drugs might increase the risk of hypotension.
Read the full Algal Oil + Aliskiren interactionAlogliptinNesina
How Alogliptin interacts with CitraNatal Assure DHA Soft Gel — through 1 ingredient. Tap an ingredient for the detail:
Algal OilAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking algal oil with antidiabetes drugs might interfere with the effects of antidiabetes drugs and reduce their effects.
Read the full Algal Oil + Alogliptin interactionAlogliptin, MetforminKazano
How Alogliptin, Metformin interacts with CitraNatal Assure DHA Soft Gel — through 1 ingredient. Tap an ingredient for the detail:
Algal OilAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking algal oil with antidiabetes drugs might interfere with the effects of antidiabetes drugs and reduce their effects.
Read the full Algal Oil + Alogliptin, Metformin interactionAlogliptin, PioglitazoneOseni
How Alogliptin, Pioglitazone interacts with CitraNatal Assure DHA Soft Gel — through 1 ingredient. Tap an ingredient for the detail:
Algal OilAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking algal oil with antidiabetes drugs might interfere with the effects of antidiabetes drugs and reduce their effects.
Read the full Algal Oil + Alogliptin, Pioglitazone interactionAmbrisentanLetairis, Volibris
How Ambrisentan interacts with CitraNatal Assure DHA Soft Gel — through 1 ingredient. Tap an ingredient for the detail:
Algal OilAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking algal oil with antihypertensive drugs might increase the risk of hypotension.
Read the full Algal Oil + Ambrisentan interactionAmilorideAmilamont, Midamor
How Amiloride interacts with CitraNatal Assure DHA Soft Gel — through 1 ingredient. Tap an ingredient for the detail:
Algal OilAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking algal oil with antihypertensive drugs might increase the risk of hypotension.
Read the full Algal Oil + Amiloride interactionAmiloride, HydrochlorothiazideAmil-Co, Amilzide, Moduret 25, Moduretic
How Amiloride, Hydrochlorothiazide interacts with CitraNatal Assure DHA Soft Gel — through 1 ingredient. Tap an ingredient for the detail:
Algal OilAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking algal oil with antihypertensive drugs might increase the risk of hypotension.
Read the full Algal Oil + Amiloride, Hydrochlorothiazide interactionAmlodipineNorliqva
How Amlodipine interacts with CitraNatal Assure DHA Soft Gel — through 1 ingredient. Tap an ingredient for the detail:
Algal OilAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking algal oil with antihypertensive drugs might increase the risk of hypotension.
Read the full Algal Oil + Amlodipine interactionAmlodipine BenzoateKaterzia
How Amlodipine Benzoate interacts with CitraNatal Assure DHA Soft Gel — through 1 ingredient. Tap an ingredient for the detail:
Algal OilAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking algal oil with antihypertensive drugs might increase the risk of hypotension.
Read the full Algal Oil + Amlodipine Benzoate interactionAmlodipine BesilateIstin
How Amlodipine Besilate interacts with CitraNatal Assure DHA Soft Gel — through 1 ingredient. Tap an ingredient for the detail:
Algal OilAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking algal oil with antihypertensive drugs might increase the risk of hypotension.
Read the full Algal Oil + Amlodipine Besilate interactionAmlodipine BesylateNorvasc
How Amlodipine Besylate interacts with CitraNatal Assure DHA Soft Gel — through 1 ingredient. Tap an ingredient for the detail:
Algal OilAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking algal oil with antihypertensive drugs might increase the risk of hypotension.
Read the full Algal Oil + Amlodipine Besylate interactionAmlodipine Besylate, BenazeprilLotrel
How Amlodipine Besylate, Benazepril interacts with CitraNatal Assure DHA Soft Gel — through 1 ingredient. Tap an ingredient for the detail:
Algal OilAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking algal oil with antihypertensive drugs might increase the risk of hypotension.
Read the full Algal Oil + Amlodipine Besylate, Benazepril interactionAmlodipine, CelecoxibConsensi
How Amlodipine, Celecoxib interacts with CitraNatal Assure DHA Soft Gel — through 1 ingredient. Tap an ingredient for the detail:
Algal OilAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking algal oil with antihypertensive drugs might increase the risk of hypotension.
Read the full Algal Oil + Amlodipine, Celecoxib interactionAmmonium ChlorideAmmonium Chloride
How Ammonium Chloride interacts with CitraNatal Assure DHA Soft Gel — through 1 ingredient. Tap an ingredient for the detail:
Algal OilAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking algal oil with antihypertensive drugs might increase the risk of hypotension.
Read the full Algal Oil + Ammonium Chloride interactionAntidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) InhibitorGlyxambi
How Antidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) Inhibitor interacts with CitraNatal Assure DHA Soft Gel — through 1 ingredient. Tap an ingredient for the detail:
Algal OilAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking algal oil with antidiabetes drugs might interfere with the effects of antidiabetes drugs and reduce their effects.
Read the full Algal Oil + Antidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) Inhibitor interactionAprocitentanTryvio
How Aprocitentan interacts with CitraNatal Assure DHA Soft Gel — through 1 ingredient. Tap an ingredient for the detail:
Algal OilAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking algal oil with antihypertensive drugs might increase the risk of hypotension.
Read the full Algal Oil + Aprocitentan interactionAtenololAtenix, Tenormin
How Atenolol interacts with CitraNatal Assure DHA Soft Gel — through 1 ingredient. Tap an ingredient for the detail:
Algal OilAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking algal oil with antihypertensive drugs might increase the risk of hypotension.
Read the full Algal Oil + Atenolol interactionAtenolol, ChlortalidoneAtenixCo, Tenoret 50, Totaretic
How Atenolol, Chlortalidone interacts with CitraNatal Assure DHA Soft Gel — through 1 ingredient. Tap an ingredient for the detail:
Algal OilAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking algal oil with antihypertensive drugs might increase the risk of hypotension.
Read the full Algal Oil + Atenolol, Chlortalidone interactionAtenolol, ChlorthalidoneTenoretic
How Atenolol, Chlorthalidone interacts with CitraNatal Assure DHA Soft Gel — through 1 ingredient. Tap an ingredient for the detail:
Algal OilAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking algal oil with antihypertensive drugs might increase the risk of hypotension.
Read the full Algal Oil + Atenolol, Chlorthalidone interactionAzilsartanEdarbi
How Azilsartan interacts with CitraNatal Assure DHA Soft Gel — through 1 ingredient. Tap an ingredient for the detail:
Algal OilAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking algal oil with antihypertensive drugs might increase the risk of hypotension.
Read the full Algal Oil + Azilsartan interactionAzilsartan, ChlorthalidoneEdarbyclor
How Azilsartan, Chlorthalidone interacts with CitraNatal Assure DHA Soft Gel — through 1 ingredient. Tap an ingredient for the detail:
Algal OilAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking algal oil with antihypertensive drugs might increase the risk of hypotension.
Read the full Algal Oil + Azilsartan, Chlorthalidone interactionBenazeprilLotensin
How Benazepril interacts with CitraNatal Assure DHA Soft Gel — through 1 ingredient. Tap an ingredient for the detail:
Algal OilAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking algal oil with antihypertensive drugs might increase the risk of hypotension.
Read the full Algal Oil + Benazepril interactionBenazepril, HydrochlorothiazideLotensin HCT
How Benazepril, Hydrochlorothiazide interacts with CitraNatal Assure DHA Soft Gel — through 1 ingredient. Tap an ingredient for the detail:
Algal OilAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking algal oil with antihypertensive drugs might increase the risk of hypotension.
Read the full Algal Oil + Benazepril, Hydrochlorothiazide interactionBendroflumethiazideAprinox, Naturetin, Neo-NaClex
How Bendroflumethiazide interacts with CitraNatal Assure DHA Soft Gel — through 1 ingredient. Tap an ingredient for the detail:
Algal OilAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking algal oil with antihypertensive drugs might increase the risk of hypotension.
Read the full Algal Oil + Bendroflumethiazide interactionBendroflumethiazide, NadololCorzide
How Bendroflumethiazide, Nadolol interacts with CitraNatal Assure DHA Soft Gel — through 1 ingredient. Tap an ingredient for the detail:
Algal OilAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking algal oil with antihypertensive drugs might increase the risk of hypotension.
Read the full Algal Oil + Bendroflumethiazide, Nadolol interactionEach ingredient & the kinds of drugs it affects
For each ingredient in CitraNatal Assure DHA Soft Gel with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Algal Oil
Antidiabetes Drugs
Theoretically, taking algal oil with antidiabetes drugs might interfere with the effects of antidiabetes drugs and reduce their effects.
Most algal oil contains docosahexaenoic acid (DHA). Clinical research in people with type 2 diabetes, including those taking antidiabetes drugs, shows that taking DHA 4 grams daily for 6 weeks increases fasting blood glucose levels by about 18 mg/dL when compared with taking olive oil.
Antihypertensive Drugs
Theoretically, taking algal oil with antihypertensive drugs might increase the risk of hypotension.
Algal oil usually contains docosahexaenoic acid (DHA) and/or eicosapentaenoic acid (EPA). There is evidence that fish oil, which also contains DHA and EPA, can modestly lower blood pressure and might have additive effects in patients treated with antihypertensive drugs.
Anticoagulant/Antiplatelet Drugs
Theoretically, algal oil may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
The risk of interaction is highest for algal oil containing high amounts (> 2 grams daily) of eicosapentaenoic acid (EPA), or EPA and docosahexaenoic acid (DHA). High doses of EPA or oils containing EPA and DHA can reduce platelet aggregation in humans. However, most algal oil contains very little EPA and larger amounts of DHA. While some conflicting evidence exist, most research shows that DHA alone does not affect blood clotting.
Brand information
Manufacturer and brand details for CitraNatal Assure DHA Soft Gel, from the product label.
Mission Pharmacal CitraNatal
See all Mission Pharmacal CitraNatal products- Name
- Mission Pharmacal Company
- City
- San Antonio
- State
- TX
- ZipCode
- 78230 1355
- Phone Number
- (800) 298-1087
- Web Address
- citranatal.com
CitraNatal Assure DHA Soft Gel by Mission Pharmacal CitraNatal: Common Questions
Does CitraNatal Assure DHA Soft Gel by Mission Pharmacal CitraNatal interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Is this safe to take during pregnancy?
Can I take this while breastfeeding?
What is DHA and why is it in prenatal supplements?
Can algal oil raise my cholesterol?
Will this help my cognitive function or memory?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if CitraNatal Assure DHA Soft Gel is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind CitraNatal Assure DHA Soft Gel’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
CitraNatal Assure DHA Soft Gel's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 43 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Algal Oil 43 references
- Prisco D, Paniccia R, Bandinelli B, et al. Effect of medium-term supplementation with a moderate dose of n-3 polyunsaturated fatty acids on blood pressure in mild hypertensive patients. Thromb Res 1998;1:105-12.
- Grimsgaard S, Bonaa KH, Hansen JB, Nordoy A. Highly purified eicosapentaenoic acid and docosahexaenoic acid in humans have similar triacylglycerol-lowering effects but divergent effects on serum fatty acids. Am J Clin Nutr 1997;66:649-59.
- Toft I, Bonaa KH, Ingebretsen OC, et al. Effects of n-3 polyunsaturated fatty acids on glucose homeostasis and blood pressure in essential hypertension. A randomized, controlled trial. Ann Intern Med 1995;123:911-8.
- Sacks FM, Hebert P, Appel LJ, et al. Short report: the effect of fish oil on blood pressure and high-density lipoprotein-cholesterol levels in phase I of the trials of hypertension prevention. J Hypertens 1994;12:209-13.
- Vandongen R, Mori TA, Burke V, et al. Effects on blood pressure of omega 3 fats in subjects at increased risk of cardiovascular disease. Hypertension 1993;22:371-9. PubMed
- FDA. Center for Food Safety and Applied Nutrition. Letter regarding dietary supplement health claim for omega-3 fatty acids and coronary heart disease. Available at: http://www.fda.gov/ohrms/dockets/dockets/95s0316/95s-0316-Rpt0272-38-Appendix-D-Reference
- Leaf A. On the reanalysis of the GISSI-Prevenzione. Circulation 2002;105:1874-5. PubMed
- Connor WE. n-3 Fatty acids from fish and fish oil: panacea or nostrum? Am J Clin Nutr 2001;74;415-6. PubMed
- Calder PC. N-3 polyunsaturated fatty acids, inflammation and immunity: pouring oil on troubled waters or another fishy tale? Nutr Res 2001;21:309-41. DOI
- Pedersen HS, Mulvad G, Seidelin KN, et al. N-3 fatty acids as a risk factor for haemorrhagic stroke. Lancet 1999;353:812-3. PubMed
- Terano T, Hirai A, Hamazaki T, et al. Effect of oral administration of highly purified eicosapentaenoic acid on platelet function, blood viscosity and red cell deformability in healthy human subjects. Atherosclerosis 1983;46:321-31.. PubMed
- Kris-Ehterton PM, Harris WS, Appel LJ, et al. Fish consumption, fish oil, omega-3 fatty acids, and cardiovascular disease. Circulation 2002;106:2747-57. PubMed
- Woodman RJ, Mori TA, Burke V, et al. Effects of purified eicosapentaenoic and docosahexaenoic acids on glycemic control, blood pressure, and serum lipids in type 2 diabetic patients with treated hypertension. Am J Clin Nutr 2002;76:1007-15.. PubMed
- Marangell LB, Martinez JM, Zboyan HA, et al. A double-blind, placebo-controlled study of the omega-3 fatty acid docosahexaenoic acid in the treatment of major depression. Am J Psychiatry 2003;160:996-8.. PubMed
- Leng GC, Smith FB, Fowkes FG, et al. Relationship between plasma essential fatty acids and smoking, serum lipids, blood pressure and haemostatic and rheological factors. Prostaglandins Leukot Essent Fatty Acids 1994;51:101-8. PubMed
- Nelson GJ, Schmidt PS, Bartolini GL, et al. The effect of dietary docosahexaenoic acid on platelet function, platelet fatty acid composition, and blood coagulation in humans. Lipids 1997;32:1129-36. PubMed
- Wheaton DH, Hoffman DR, Locke KG, et al. Biological safety assessment of docosahexaenoic acid supplementation in a randomized clinical trial for X-linked retinitis pigmentosa. Arch Ophthalmol 2003;121:1269-78. PubMed
- Svaneborg N, Kristensen SD, Hansen LM, et al. The acute and short-time effect of supplementation with the combination of n-3 fatty acids and acetylsalicylic acid on platelet function and plasma lipids. Thromb Res 2002;105:311-6. PubMed
- Yokoyama M, Origasa H, Matsuzaki M, et al. Effects of eicosapentaenoic acid on major coronary events in hypercholesterolaemic patients (JELIS): a randomised open-label, blinded endpoint analysis. Lancet 2007;369:1090-8. PubMed
- von Houwelingen R, Nordøy A, van der Beek E, et al. Effect of a moderate fish intake on blood pressure, bleeding time, hematology, and clinical chemistry in healthy males. Am J Clin Nutr. 1987 Sep;46(3):424-36. PubMed
- Goodnight SH Jr, Harris WS, Connor WE. The effects of dietary omega 3 fatty acids on platelet composition and function in man: a prospective, controlled study. Blood. 1981 Nov;58(5):880-5. DOI
- Mori, T. A., Bao, D. Q., Burke, V., Puddey, I. B., and Beilin, L. J. Docosahexaenoic acid but not eicosapentaenoic acid lowers ambulatory blood pressure and heart rate in humans. Hypertension 1999;34(2):253-260. PubMed
- Nestel, P., Shige, H., Pomeroy, S., Cehun, M., Abbey, M., and Raederstorff, D. The n-3 fatty acids eicosapentaenoic acid and docosahexaenoic acid increase systemic arterial compliance in humans. Am.J.Clin.Nutr. 2002;76(2):326-330. PubMed
- Woodman, R. J., Mori, T. A., Burke, V., Puddey, I. B., Barden, A., Watts, G. F., and Beilin, L. J. Effects of purified eicosapentaenoic acid and docosahexaenoic acid on platelet, fibrinolytic and vascular function in hypertensive type 2 diabetic patients PubMed
- Theobald, H. E., Goodall, A. H., Sattar, N., Talbot, D. C., Chowienczyk, P. J., and Sanders, T. A. Low-dose docosahexaenoic acid lowers diastolic blood pressure in middle-aged men and women. J Nutr 2007;137(4):973-978.
- Mischoulon D, Best-Popescu C, Laposata M, et al. A double-blind dose-finding pilot study of docosahexaenoic acid (DHA) for major depressive disorder. Eur Neuropsychopharmacol. 2008;18(9):639-645. PubMed
- Arterburn, L. M., Oken, H. A., Bailey, Hall E., Hamersley, J., Kuratko, C. N., and Hoffman, J. P. Algal-oil capsules and cooked salmon: nutritionally equivalent sources of docosahexaenoic acid. J Am Diet Assoc 2008;108(7):1204-1209. PubMed
- Zucker, M. L., Bilyeu, D. S., Helmkamp, G. M., Harris, W. S., and Dujovne, C. A. Effects of dietary fish oil on platelet function and plasma lipids in hyperlipoproteinemic and normal subjects. Atherosclerosis 1988;73(1):13-22. PubMed
- Bernstein AM, Ding EL, Willett WC, Rimm EB. A meta-analysis shows that docosahexaenoic acid from algal oil reduces serum triglycerides and increases HDL-cholesterol and LDL-cholesterol in persons without coronary heart disease. J Nutr. 2012;142(1):99-104.
- Carlson SE, Colombo J, Gajewski BJ, Gustafson KM, Mundy D, Yeast J, Georgieff MK, Markley LA, Kerling EH, Shaddy DJ. DHA supplementation and pregnancy outcomes. Am J Clin Nutr. 2013 Apr;97(4):808-15. PubMed
- Fu YQ, Zheng JS, Yang B, Li D. Effect of individual omega-3 fatty acids on the risk of prostate cancer: a systematic review and dose-response meta-analysis of prospective cohort studies. J Epidemiol. 2015;25(4):261-74. PubMed
- Imhoff-Kunsch B, Stein AD, Villalpando S, Martorell R, Ramakrishnan U. Docosahexaenoic acid supplementation from mid-pregnancy to parturition influenced breast milk fatty acid concentrations at 1 month postpartum in Mexican women. J Nutr. 2011 Feb;141(2): PubMed
- Mulder KA, King DJ, Innis SM. Omega-3 fatty acid deficiency in infants before birth identified using a randomized trial of maternal DHA supplementation in pregnancy. PLoS One. 2014 Jan 10;9(1):e83764. PubMed
- Richardson AJ, Burton JR, Sewell RP, Spreckelsen TF, Montgomery P. Docosahexaenoic acid for reading, cognition and behavior in children aged 7-9 years: a randomized, controlled trial (the DOLAB Study). PLoS One. 2012;7(9):e43909. PubMed
- Ballantyne CM, Bays HE, Kastelein JJ, Stein E, Isaacsohn JL, Braeckman RA, Soni PN. Efficacy and safety of eicosapentaenoic acid ethyl ester (AMR101) therapy in statin-treated patients with persistent high triglycerides (from the ANCHOR study). Am J Cardi PubMed
- FDA announces qualified health claims for omega-3 fatty acids. Available at: https://www.fda.gov/Food/LabelingNutrition/ucm072756.htm. Accessed April 15 2019.
- Breastfeeding and the use of human milk. Section on Breastfeeding. Pediatrics. 2012;129(3):e827-41. PubMed
- Zhang Z, Fulgoni VL, Kris-Etherton PM, Mitmesser SH. Dietary Intakes of EPA and DHA Omega-3 Fatty Acids among US Childbearing-Age and Pregnant Women: An Analysis of NHANES 2001-2014. Nutrients. 2018;10(4). PubMed
- Montgomery P, Spreckelsen TF, Burton A, Burton JR, Richardson AJ. Docosahexaenoic acid for reading, working memory and behavior in UK children aged 7-9: A randomized controlled trial for replication (the DOLAB II study). PLoS One. 2018;13(2):e0192909. PubMed
- Rao A, Briskey D, Nalley JO, Ganuza E. Omega-3 eicosapentaenoic acid (EPA) rich extract from the microalga Nannochloropsis decreases cholesterol in healthy individuals: A double-blind, randomized, placebo-controlled, three-month supplementation study. Nut PubMed
- Marc I, Piedboeuf B, Lacaze-Masmonteil T, et al. Effect of maternal docosahexaenoic acid supplementation on bronchopulmonary dysplasia-free survival in breastfed preterm infants: A randomized clinical trial. JAMA. 2020;324(2):157-167. PubMed
- Fougère H, Bilodeau JF, Lavoie PM, et al. Docosahexaenoic acid-rich algae oil supplementation on breast milk fatty acid profile of mothers who delivered prematurely: a randomized clinical trial. Sci Rep 2021;11(1):21492. PubMed
- Yang Y, Li G, Li F, et al. Impact of DHA from algal oil on the breast milk DHA levels of lactating women: A randomized controlled trial in China. Nutrients 2022;14(16):3410. PubMed
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