Interactions on record — worth a quick check against your medications. Based on 4 of 5 ingredients. Check your meds →
Dietary supplement

CLA + Carnitine Fruit Punch Ingredients & Drug Interactions

by BPI Sports

CLA + Carnitine Fruit Punch label
See full label image
Powder Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking CLA + Carnitine Fruit Punch against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

CLA + Carnitine Fruit Punch is a dietary supplement by BPI Sports with 5 active ingredients. Its ingredients are commonly taken for bone health and osteoporosis, correcting vitamin d deficiency, immune system support.Based on those ingredients, 879 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Vitamin D3, Safflower Seed Oil, Powder, Coconut Oil powder. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against CLA + Carnitine Fruit Punch by BPI Sports

Ask about any prescription or over-the-counter medication and we check it for interactions with CLA + Carnitine Fruit Punch by BPI Sports — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
Prefer a human? Send your question to our licensed pharmacists — free, answered by email within 24 hours.

HelloPharmacist Scorecard of CLA + Carnitine Fruit Punch by BPI Sports

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 1 of its 5 active ingredients.
  • “Omega 6 Fatty Acids & CLA Matrix” is a proprietary blend — the label gives one combined amount (2.50 Gram(s)) without saying how much of each component you get.
  • “Carnitine Matrix” is a proprietary blend — the label gives one combined amount (2 Gram(s)) without saying how much of each component you get.

This powder contains 5 active ingredients. Vitamin D3 is a fat-soluble vitamin that helps your body absorb calcium and regulate blood calcium levels.

Avocado Oil powder, Coconut Oil powder, and Safflower Seed Oil powder are concentrated forms of plant oils, each bringing different fatty acids to the mix. Carnitine is an amino acid that supports energy production in your cells.

The product also contains several inactive ingredients—maltodextrin, silica, citric acid, natural and artificial flavors, sucralose, malic acid, acesulfame potassium, and sodium chloride—which are fillers, thickeners, and flavor enhancers typical of powdered supplements.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded its ingredients' overall clinical evidence instead.

Strong

Strong clinical evidence supports its ingredients for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredients' overall clinical evidence instead.
  • On file: Familial hypophosphatemia — rated "Effective" (Vitamin D) (Natural Medicines).
  • On file: Osteomalacia — rated "Effective" (Vitamin D) (Natural Medicines).
  • On file: Renal osteodystrophy — rated "Effective" (Vitamin D) (Natural Medicines).
  • On file: Rickets — rated "Effective" (Vitamin D) (Natural Medicines).
  • On file: Hypoparathyroidism — rated "Effective" (Vitamin D) (Natural Medicines).

Vitamin D3 is effective for treating rickets, osteomalacia (soft bones), renal bone disease, and certain forms of low blood phosphate and low parathyroid hormone—all serious medical conditions that require medical supervision. For the other active ingredients, the evidence we hold doesn't establish that they're effective for any condition.

Avocado oil is possibly effective for high cholesterol, but Coconut oil, Safflower oil, and Carnitine lack reliable evidence for any of the conditions studied. This product is marketed as a fitness supplement, but its individual ingredients haven't been proven effective for athletic performance, fat loss, or muscle gain in our data.

The evidence, ingredient by ingredient Vitamin D Avocado Coconut Safflower

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 4 of the 4 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 4 of 4.
  • General safety write-ups exist for 4 of 4.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Vitamin D3 is generally well tolerated at recommended doses, but very high doses over time can cause toxicity—symptoms include high calcium levels (hypercalcemia), bone loss in adults, and slowed growth in children. The facts advise using vitamin D during pregnancy only under your doctor's guidance, and checking with your doctor before taking higher amounts while breastfeeding.

Avocado oil is safe as a food but concentrated supplements haven't been well studied in pregnancy or breastfeeding; in rare cases, avocado can trigger a severe allergic reaction in latex-sensitive people or a serious delayed food reaction (FPIES) with vomiting and diarrhea, mostly in infants and young children. Coconut oil is likely safe in pregnancy and generally safe when eaten in normal amounts, but high-dose supplements aren't well studied; allergic reactions ranging from hives to anaphylaxis are possible in those with coconut hypersensitivity.

Safflower oil in food is usually tolerated, but concentrated extracts are linked to rare liver failure cases, and safflower flower may stimulate the uterus—avoid medicinal amounts in pregnancy. No pregnancy or breastfeeding data is on file for Carnitine or the blended ingredients.

Side effects, ingredient by ingredient Vitamin D Avocado Coconut Safflower

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 4 of the 4 matched ingredients can interact with medications — Safflower, Avocado, Vitamin D, Coconut.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications; heart-rhythm medications.
  • For scale: 880 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

You should double-check any thiazide diuretics (water pills), heart rhythm drugs like verapamil and diltiazem, the cholesterol drug atorvastatin, heart medication digoxin, blood thinners like warfarin, diabetes medications, and antiplatelet drugs. These carry Moderate severity interactions with ingredients in this product.

Additionally, inform your pharmacist if you take any medications processed by your liver through CYP3A4, as vitamin D may affect how quickly they're cleared from your body.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with strong clinical evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.

If you take any blood thinner, heart rhythm medication, diabetes drug, or cholesterol medication, check your prescriptions with the tool on this page before starting. This product is not proven effective for any specific health condition in our data.

Stick to the recommended dose to avoid vitamin D toxicity, and talk to your pharmacist if you're pregnant, breastfeeding, or have a history of liver problems or allergies to tree nuts or latex.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 4 of 5 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Mar 25, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about CLA + Carnitine Fruit Punch, straight from the product label.

Brand BPI Sports
Barcode (UPC) 811213026653
Net contents 12.34 Ounce(s); 350 Gram(s)
Market status On market
Date entered into DSLD Mar 25, 2025
DSLD ID 326512
Product type Other Combinations
Supplement form Powder
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for CLA + Carnitine Fruit Punch by BPI Sports, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
7 Gram(s)
Maximum serving Sizes:
7 Gram(s)
Servings per container
50
UPC/BARCODE
811213026653
IngredientAmount% DV
Calories10 Calorie(s)--
Calories from Fat10 Calorie(s)--
Vitamin D3250 mcg1250%
Total Fat1 Gram(s)2%
Avocado Oil powder0 NP--
Coconut Oil powder0 NP--
Carnitine0 NP--
Safflower Seed Oil, Powder0 NP--
Omega 6 Fatty Acids & CLA Matrix2.5 Gram(s)--
Carnitine Matrix2 Gram(s)--

Other ingredients: Maltodextrin, Silica, Citric Acid, Natural & Artificial Flavors, Sucralose, Malic Acid, Acesulfame Potassium, Sodium Chloride

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested use: 01 Take 1 serving (1 scoop) 02 Mix in 8 oz of cold water in the morning 03 And take 1 serving (1 scoop) in the evening

Precautions

Warnings: Not intended for use by persons under age 18.

Do not exceed recommended dose.

Get the consent of a licensed physician before using this product, especially if you are taking medication, have a medical condition, you are pregnant, nursing or thinking about becoming pregnant.

Discontinue use two weeks prior to surgery.

Keep this product and all supplements out of the reach of children.

To report an adverse event or for more information call: 954.926.0900

Storage

Store in a cool, dry place.

Seals/Symbols

Quality Tested Quality Verified cGMP Good Manufacturing practices Made in the USA with domestic and international ingredients.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Formula

Omega 6 fatty acids Fruit Punch natural and artificial flavors

General Statements

Brand new!

Follow us: Facebook / BPIOnline Instagram @BPI_Sports

Formulation

May help to: Reduce body fat Promote lean muscle Non-stim weight loss support When combined with a proper exercise and nutrition regimen.

Non-stim weight loss support No artificial colors

FDA Statement of Identity

Dietary Supplement

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

CLA + Carnitine Fruit Punch by BPI Sports label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

CLA + Carnitine Fruit Punch label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in CLA + Carnitine Fruit Punch by BPI Sports

These are the 5 active ingredients this product is made of. Select any to open its full monograph.

Serving size7 Gram(s) Dosage formPowder Servings per container50 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Vitamin D3

Interacts with
715 drugs
250 mcg per serving Form: Cholecalciferol

Vitamin D is a fat-soluble vitamin that helps your body absorb calcium and is important for healthy bones, muscles, and immune function. Many people,...

Vitamin D3 monograph & interactions

Omega 6 Fatty Acids & CLA Matrix

2.5 Gram(s) per serving

Carnitine Matrix

2 Gram(s) per serving
  • › Carnitine

Other (inactive) ingredients: Maltodextrin, Silica, Citric Acid, Natural & Artificial Flavors, Sucralose, Malic Acid, Acesulfame Potassium, Sodium Chloride. These complete the product’s ingredient list but are not active constituents.

Interaction report

CLA + Carnitine Fruit Punch by BPI Sports Drug Interactions

Want to check YOUR meds against CLA + Carnitine Fruit Punch?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
879Drugs
284 Moderate 595 Minor

Ingredients driving the most interactions

Vitamin D3 715
Safflower Seed Oil, Powder 208
Coconut Oil powder 86
Avocado Oil powder 2

Individual Drug Interactions

The ingredients in CLA + Carnitine Fruit Punch interact with 879 drugs. Click any drug to see the details.

4 of the 5 ingredients in CLA + Carnitine Fruit Punch interact with drugs. Each result below shows which ingredient is responsible. Vitamin D3 Safflower Seed Oil, Powder Coconut Oil powder Avocado Oil powder

Each ingredient & the kinds of drugs it affects

For each ingredient in CLA + Carnitine Fruit Punch with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Vitamin D38 drug types · 715 drugs

Aluminum

Vitamin D might increase aluminum absorption and toxicity, but this has only been reported in people with renal failure.
The protein that transports calcium across the intestinal wall can also bind and transport aluminum. This protein is stimulated by vitamin D, which may therefore increase aluminum absorption. This mechanism may contribute to increased aluminum levels and toxicity in people with renal failure, when they take vitamin D and aluminum-containing phosphate binders chronically.

Likelihood Probable Evidence B
Atorvastatin (Lipitor)

Vitamin D might reduce absorption of atorvastatin.
A small, low-quality clinical study shows that taking vitamin D reduces levels of atorvastatin and its active metabolites by up to 55%. However, while atorvastatin levels decreased, total cholesterol, low-density lipoprotein (LDL) cholesterol, and high-density lipoprotein (HDL) cholesterol levels did not substantially change. Atorvastatin is metabolized in the gut by CYP3A4 enzymes, and researchers theorized that vitamin D might induce CYP3A4, causing reduced levels of atorvastatin. However, this proposed mechanism was not specifically studied.

Likelihood Probable Evidence B
Calcipotriene (Dovonex)

Taking calcipotriene with vitamin D increases the risk for hypercalcemia.
Calcipotriene is a vitamin D analog used topically for psoriasis. It can be absorbed in sufficient amounts to cause systemic effects, including hypercalcemia. Theoretically, combining calcipotriene with vitamin D supplements might increase the risk of hypercalcemia.

Likelihood Probable Evidence D
Digoxin (Lanoxin)

Theoretically, hypercalcemia induced by high-dose vitamin D can increase the risk of arrhythmia from digoxin.
High doses of vitamin D can cause hypercalcemia. Hypercalcemia increases the risk of fatal cardiac arrhythmias with digoxin. Avoid vitamin D doses above the tolerable upper intake level (4000 IU daily for adults) and monitor serum calcium levels in people taking vitamin D and digoxin concurrently.

Likelihood Possible Evidence D
Diltiazem (Cardizem, Others)

Theoretically, hypercalcemia induced by high-dose vitamin D can reduce the therapeutic effects of diltiazem for arrhythmia.
High doses of vitamin D can cause hypercalcemia. Hypercalcemia can reduce the effectiveness of verapamil in atrial fibrillation. Theoretically this could also occur with diltiazem. Avoid vitamin D doses above the tolerable upper intake level (4000 IU daily for adults) and monitor serum calcium levels in people taking vitamin D and diltiazem concurrently.

Likelihood Probable Evidence B
Thiazide Diuretics

Theoretically, taking thiazide diuretics and high-dose vitamin D can increase the risk of hypercalcemia.
Thiazide diuretics decrease urinary calcium excretion, which could lead to hypercalcemia if vitamin D supplements are taken concurrently. This has been reported in people being treated with vitamin D for hypoparathyroidism, and also in elderly people with normal parathyroid function who were taking a thiazide, vitamin D, and calcium-containing antacids daily.

Likelihood Probable Evidence D
Verapamil (Calan, Others)

Hypercalcemia induced by high-dose vitamin D can reduce the therapeutic effects of verapamil for arrhythmia.
Hypercalcemia due to high doses of vitamin D can reduce the effectiveness of verapamil in atrial fibrillation. Avoid vitamin D doses above the tolerable upper intake level (4000 IU daily for adults) and monitor serum calcium levels in people taking vitamin D and verapamil concurrently.

Likelihood Probable Evidence B
Cytochrome P450 3A4 (Cyp3A4) Substrates

Vitamin D might induce CYP3A4 enzymes and reduce the bioavailability of CYP3A4 substrates.
There is some concern that vitamin D might induce CYP3A4. In vitro research suggests that vitamin D induces CYP3A4 transcription. Additionally, observational research has found that increased UV light exposure and serum vitamin D levels are associated with decreased serum levels of CYP3A4 substrates such as tacrolimus and sirolimus, while no association between UV light exposure or vitamin D levels and levels of mycophenolic acid, a non-CYP3A4 substrate, was found. A small, low-quality clinical study shows that taking vitamin D reduces levels of the CYP3A4 substrate atorvastatin and its active metabolites by up to 55%; however, the clinical effects of atorvastatin were not reduced. While researchers theorized that vitamin D might induce CYP3A4, this proposed mechanism was not specifically studied.

Likelihood Possible Evidence D
Vitamin D3 full monograph & interactions

Safflower Seed Oil, Powder3 drug types · 208 drugs

Anticoagulant/Antiplatelet Drugs

High doses of safflower oil might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Small clinical studies show that taking safflower oil, approximately 55 grams daily for 2-3 weeks, decreases platelet aggregation. However, taking lower doses of safflower oil, such as 5 grams daily for 4 weeks, does not seem to affect platelet function. In one case report, a 74-year-old male stabilized on warfarin developed urinary tract bleeding and an elevated INR after taking a safflower extract 20 grams daily for 14 days.

Likelihood Possible Evidence B
Antidiabetes Drugs

Theoretically, safflower oil might alter the effects of antidiabetes drugs.
Some clinical research shows that taking safflower oil 10 grams daily for 3 weeks can increase fasting blood glucose in patients with type 2 diabetes. However, clinical research in patients with metabolic syndrome with or without impaired glucose tolerance shows that taking safflower oil 8 grams daily for 12 weeks reduces fasting glucose levels by around 8 mg/dL. Some clinical research also shows that taking safflower oil 8 grams daily for 16 weeks does not affect fasting glucose levels in patients with type 2 diabetes.

Likelihood Possible Evidence B
Warfarin

Theoretically, safflower oil might increase the risk of bleeding when taken with warfarin.
In one case report, a 74-year-old male stabilized on warfarin developed urinary tract bleeding and an elevated INR after taking a safflower extract 20 grams daily for 14 days.

Likelihood Possible Evidence D
Safflower Seed Oil, Powder full monograph & interactions

Coconut Oil powder1 drug type · 86 drugs

Antidiabetes Drugs

Theoretically, taking coconut with antidiabetes drugs might increase the risk of hypoglycemia.
Animal research suggests that coconut milk might increase insulin levels and/or decrease blood glucose levels.

Likelihood Unlikely Evidence D
Coconut Oil powder full monograph & interactions

Avocado Oil powder1 drug type · 2 drugs

Warfarin (Coumadin)

Avocado may antagonize the anticoagulant effects of warfarin.
Avocado may antagonize the anticoagulant effects of warfarin; however, there has been only one case report of this interaction.

Likelihood Unlikely Evidence D
Avocado Oil powder full monograph & interactions
The maker

Brand information

Manufacturer and brand details for CLA + Carnitine Fruit Punch, from the product label.

BPI Sports

See all BPI Sports products
Name
BPI Sports
Street Address
3149 SW 42nd St. Suite 200
City
Hollywood
State
FL
ZipCode
33312
Phone Number
954.926.0900
Web Address
www.bpisports.com
Pharmacist Counseling Corner

CLA + Carnitine Fruit Punch by BPI Sports: Common Questions

Does CLA + Carnitine Fruit Punch by BPI Sports interact with any medications?
Yes. Based on its ingredients, CLA + Carnitine Fruit Punch has a known interaction with 879 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
CLA + Carnitine Fruit Punch contains 5 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will this help me lose weight or build muscle?
The ingredients—CLA, carnitine, and the plant oils—aren't proven effective for weight loss or muscle gain in the evidence we hold. While they're marketed for fitness, we don't have clinical data showing they work for those purposes in this product.
Is it safe if I'm allergic to nuts or latex?
If you have a latex allergy, be cautious: avocado can trigger cross-reactions in latex-sensitive people. If you're allergic to tree nuts, note that coconut is treated as a tree nut for allergen purposes in the US, and can cause reactions ranging from hives to anaphylaxis in some people.
Can I take this while pregnant or breastfeeding?
For Vitamin D3, use only under your doctor's guidance during pregnancy, and check with your doctor before taking higher amounts while breastfeeding. Coconut oil is likely safe in pregnancy. For avocado oil and safflower oil, concentrated supplements haven't been well studied in pregnancy or breastfeeding—talk with your doctor before use. No data is on file for carnitine or the blended ingredients.
What's a 'blend' or 'matrix' ingredient?
Those are combinations of ingredients grouped together. We couldn't check the Omega 6 Fatty Acids & CLA Matrix or the Carnitine Matrix as single items because we don't have interaction data for the blend itself—only for individual ingredients within it.
Why does this product have so many inactive ingredients?
Fillers, thickeners, flavors, and sweeteners make a powder mix better, taste better, and stay stable on the shelf. Maltodextrin, silica, citric acid, and the others here are standard in supplement powders and aren't the active ingredients doing the work.
Can I take too much vitamin D from this?
Yes. Very high doses of vitamin D over time can cause toxicity with symptoms like high blood calcium, bone loss, and weak growth in children. Stick to the dose on the label and don't combine it with other vitamin D supplements without talking to your pharmacist.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if CLA + Carnitine Fruit Punch is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

CLA + Carnitine Fruit Punch label
Go deeper

The Full Monographs Behind CLA + Carnitine Fruit Punch’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Vitamin D

Interacts with 715 drugs

Vitamin D is a fat-soluble vitamin that helps your body absorb calcium and is important for healthy bones, muscles, and immune function. Many people, especially those with low sun exposure,...

Read the full Vitamin D monograph → Herb & supplement monograph

Avocado

Interacts with 2 drugs

Avocado is a nutritious fruit rich in healthy monounsaturated fats, fiber, and potassium, and eating it as part of a balanced diet may support heart health. A specific extract called avocado...

Read the full Avocado monograph → Herb & supplement monograph

Coconut

Interacts with 86 drugs

Coconut is a nutritious tropical food enjoyed as oil, water, milk, and flesh, and it is generally safe to eat in normal food amounts. While some uses (like skin moisturizing and hydration) h...

Read the full Coconut monograph → Herb & supplement monograph

Safflower

Interacts with 208 drugs

Safflower is a thistle-like plant used mainly for its seed oil (a common cooking oil) and its colorful flowers. Safflower oil is a reasonable source of unsaturated fats, but strong proof tha...

Read the full Safflower monograph →
Sources

Sources & How We Checked

CLA + Carnitine Fruit Punch's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 60 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Vitamin D 26 references
  1. McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
  2. Tatro DS, ed. Drug Interactions Facts. Facts and Comparisons Inc., St. Louis, MO. 1999.
  3. Koutkia P, Chen TC, Holick MF. Vitamin D intoxication associated with an over-the-counter supplement. N Engl J Med 2001;345:66-7. PubMed
  4. Bar-Or D, Yoel G. Calcium and calciferol antagonize effect of verapamil in atrial fibrillation. Br Med J 1981;282:1585-6.
  5. Demontis R, Leflon A, Fournier A, et al. 1 alpha(OH) vitamin D3 increases plasma aluminum in hemodialyzed patients taking AI(OH)3. Clin Nephrol 1986;26:146-9.
  6. Crowe M, Wollner L, Griffiths RA. Hypercalcemia following vitamin D and thiazide therapy in the elderly. Practitioner 1984;228:312-3.
  7. Parfitt AM. Thiazide-induced hypercalcemia in vitamin D-treated hypoparathyroidism. Ann Intern Med 1972;77:557-63. PubMed
  8. Thiazide diuretics and the risk of osteoporosis. Pharmacist's Letter/Prescriber's Letter 2003;19(11):191105.
  9. Moon J. The role of vitamin D in toxic metal absorption. J Am Coll Nutr 1994;13:559-64.
  10. Demontis R, Reissi D, Noel C, et al. Indirect clinical evidence that 1alphaOH vitamin D<SUB>3</SUB> increases the intestinal absorption of aluminum. Clin Nephrol 1989;31:123-7.
  11. Adler AJ, Berlyne GM. Duodenal aluminum absorption in the rat: effect of vitamin D. Am J Physiol 1985;249:G209-13. PubMed
  12. Schwartz JB. Effects of vitamin D supplementation in atorvastatin-treated patients: A new drug interaction with an unexpected consequence. Clin Pharmacol Ther 2009;85:198-203. PubMed
  13. Dietary reference intakes for calcium and vitamin D. Institute of Medicine, November 30, 2010. Available at: http://www.iom.edu/~/media/Files/Report%20Files/2010/Dietary-Reference-Intakes-for-Calcium-and-Vitamin-D/Vitamin%20D%20and%20Calcium%202010%20Repo
  14. Cox KA, Dunn MA. Aluminum toxicity alters the regulation of calbindin-D28k protein and mRNA expression in chick intestine. J Nutr 2001;131:2007-13. PubMed
  15. Escribano, J., Balaguer, A., Pagone, F., Feliu, A., and Roque, I. Figuls. Pharmacological interventions for preventing complications in idiopathic hypercalciuria. Cochrane.Database.Syst.Rev. 2009;(1):CD004754. PubMed
  16. Carlton, S., Clopton, D., and Cappuzzo, K. A. Vitamin D deficiency: appropriate replenishment therapies and the effects of vitamin D toxicity. Consult Pharm 2010;25(3):171-177. PubMed
  17. Wang, H., Xia, N., Yang, Y., and Peng, D. Q. Influence of vitamin D supplementation on plasma lipid profiles: a meta-analysis of randomized controlled trials. Lipids Health Dis. 2012;11:42. PubMed
  18. Turner AN, Carr Reese P, Fields KS, Anderson J, Ervin M, Davis JA, Fichorova RN, Roberts MW, Klebanoff MA, Jackson RD. A blinded, randomized controlled trial of high-dose vitamin D supplementation to reduce recurrence of bacterial vaginosis. Am J Obstet G PubMed
  19. Weiner M, Epstein FH. Signs and symptoms of electrolyte disorders. Yale J Biol Med. 1970;43(2):76-109.
  20. Lappe J, Watson P, Travers-Gustafson D, Recker R, Garland C, Gorham E, Baggerly K, McDonnell SL. Effect of Vitamin D and Calcium Supplementation on Cancer Incidence in Older Women: A Randomized Clinical Trial. JAMA. 2017 Mar 28;317(12):1234-1243. PubMed
  21. Roth DE, Leung M, Mesfin E, Qamar H, Watterworth J, Papp E. Vitamin D supplementation during pregnancy: state of the evidence from a systematic review of randomised trials. BMJ. 2017;359:j5237. PubMed
  22. Murai IH, Fernandes AL, Sales LP, et al. Effect of a single high dose of vitamin D3 on hospital length of stay in patients with moderate to severe COVID-19: A randomized clinical trial. JAMA. 2021.
  23. Wang Z, Schuetz EG, Xu Y, Thummel KE. Interplay between vitamin D and the drug metabolizing enzyme CYP3A4. J Steroid Biochem Mol Biol 2013;136:54-8. PubMed
  24. Doyle D, Browne U, Brickley A, Murphy D. Vitamin D-induced hypercalcaemia and acute kidney injury in sarcoidosis. BMJ Case Rep 2023;16(1):e250580. PubMed
  25. Williamson A, Martineau AR, Sheikh A, Jolliffe D, Griffiths CJ. Vitamin D for the management of asthma. Cochrane Database Syst Rev 2023;2(2):CD011511. PubMed
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Avocado 10 references
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Coconut 10 references
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See these in context on the Coconut monograph →

Safflower 14 references
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See these in context on the Safflower monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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