Major interaction on record — check this product against your medications before combining. Check your meds →
Dietary supplement

Clean Creatine Fruit Punch Ingredients & Drug Interactions

by BSN

Clean Creatine Fruit Punch label
See full label image
Powder Category: Other Combinations
Most serious interaction: Major
Clinical methodology reviewed by · Updated Sep 30, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Clean Creatine Fruit Punch against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Major

Clean Creatine Fruit Punch is a dietary supplement by BSN with 6 active ingredients. Its ingredients are commonly taken for exercise performance and endurance, heart health, energy support.Based on those ingredients, 1,418 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Rhodiola rosea extract, Astragalus membranaceus extract, Panax notoginseng extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Clean Creatine Fruit Punch by BSN

Ask about any prescription or over-the-counter medication and we check it for interactions with Clean Creatine Fruit Punch by BSN — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
Prefer a human? Send your question to our licensed pharmacists — free, answered by email within 24 hours.

HelloPharmacist Scorecard of Clean Creatine Fruit Punch by BSN

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Partial disclosure
Ingredient Transparency · database check
Partial

Most active ingredients list an amount, but at least one is hidden in a blend or missing.

Why this rating?
  • The label discloses an exact amount for 6 of its 8 active ingredients.
  • “Creatine Master Blend” is a proprietary blend — the label gives one combined amount (3.50 Gram(s)) without saying how much of each component you get.
  • “AstraGIN Proprietary Blend” is a proprietary blend — the label gives one combined amount (10 mg) without saying how much of each component you get.

Clean Creatine Fruit Punch contains 8 active ingredients. The main components are two forms of creatine—creatine monohydrate and creatine anhydrous—which support muscle strength and athletic performance.

Supporting ingredients include betaine anhydrous (an amino acid derivative), taurine (an amino acid), magnesium creatine chelate (a mineral complex), and plant extracts: astragalus membranaceus, Panax notoginseng, and rhodiola rosea. The product also lists inactive ingredients like citric acid, malic acid, natural and artificial flavors, and silica-based excipients used as fillers and stabilizers.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: Supports muscular strength and endurance.
  • We looked for evidence on: Athletic performance, muscle strength, exercise performance, muscle endurance.
  • The strongest evidence on file: Creatine is rated "Possibly Effective" for Athletic performance (Natural Medicines).
  • Also on file: Creatine is rated "Possibly Effective" for Muscle strength.
  • Also on file: Magnesium is rated "Possibly Ineffective" for Athletic performance.

Creatine itself is rated possibly effective for muscle strength, athletic performance, sarcopenia (age-related muscle loss), and cerebral creatine deficiency syndromes. For the other active ingredients, the evidence we hold is less clear.

Astragalus, Panax notoginseng, taurine, and rhodiola all lack sufficient reliable evidence in our data to rate them for most conditions. Betaine is rated possibly effective for high homocysteine levels and effective for homocystinuria; magnesium is effective for constipation, indigestion, low magnesium levels, and preeclampsia.

Overall, if you're taking this product for muscle and athletic benefits, the creatine content is the ingredient with the strongest evidence.

The evidence, ingredient by ingredient Taurine Betaine Anhydrous Rhodiola Creatine Magnesium Astragalus Panax Notoginseng

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 7 of the 7 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 7 of 7.
  • General safety write-ups exist for 7 of 7.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Creatine is generally well tolerated in healthy adults but requires caution in people with kidney problems; the data advises against it in pregnancy and while breastfeeding. Common side effects include dehydration, diarrhea, gastrointestinal upset, muscle cramps, and water retention.

Rare serious effects reported include kidney inflammation and muscle breakdown. Taurine is generally well tolerated short-term with common effects being constipation, diarrhea, and indigestion; long-term safety is less certain.

Astragalus may cause dizziness and rash; safety during pregnancy and breastfeeding is not established. Panax notoginseng commonly causes dry mouth, nausea, nervousness, and insomnia; the data advises against it in pregnancy due to bleeding concerns.

Rhodiola may cause dizziness or changes in saliva production and is not recommended in pregnancy or while breastfeeding. Magnesium is generally well tolerated at recommended doses, with diarrhea, nausea, and vomiting being most common.

Betaine is generally well tolerated and may cause body odor, diarrhea, nausea, or GI distress.

Side effects, ingredient by ingredient Taurine Betaine Anhydrous Rhodiola Creatine Magnesium Astragalus Panax Notoginseng

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 5 of the 7 matched ingredients can interact with medications — Rhodiola, Panax Notoginseng, Astragalus, Magnesium, Taurine.
  • The most serious interaction on file is rated Major.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; immunosuppressants / transplant drugs; diabetes medications; heart-rhythm medications; lithium; Parkinson's medications.
  • For scale: 1,419 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, double-check with your pharmacist if you take: levodopa/carbidopa (Parkinson's), blood pressure medications (especially losartan), blood thinners like warfarin, diabetes drugs, skeletal muscle relaxants, bisphosphonates, quinolone antibiotics, immunosuppressants, or lithium. Altogether, these interactions span 1,399 individual medications.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glancePartially disclosed formula with some supporting evidence for its stated purpose. Major medication interactions have been identified, and safety information is well characterized.

This product is built around creatine for muscle strength and athletic performance, with supporting ingredients of varying evidence. If you take any blood pressure drugs, diabetes medications, blood thinners, Parkinson's medications, or immunosuppressants, run this through the interaction checker first.

If you have kidney disease, talk to your pharmacist before using it. Pregnant or nursing?

Avoid it—safety data are insufficient or the product is not advised.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 8 of 8 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Apr 22, 2016.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Clean Creatine Fruit Punch, straight from the product label.

Brand BSN
Barcode (UPC) 834266002634
Net contents 1.1 lb; 500 Gram(s)
Market status On market
Date entered into DSLD Apr 22, 2016
DSLD ID 58289
Product type Other Combinations
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Clean Creatine Fruit Punch by BSN, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Scoop(s), 10 Gram(s)
Maximum serving Sizes:
1 Scoop(s), 10 Gram(s)
Servings per container
50
UPC/BARCODE
834266002634
IngredientAmount% DV
Calories10 {Calories}--
Total Carbohydrates2 Gram(s)1%
Creatine Monohydrate2.5 Gram(s)--
Astragalus membranaceus extract0 NP--
micronized Taurine1.5 Gram(s)--
Panax notoginseng extract0 NP--
Creatine Anhydrous500 mg--
Betaine Anhydrous1.25 Gram(s)--
Rhodiola rosea extract100 mg--
Magnesium Creatine Chelate500 mg--
Creatine Master Blend3.5 Gram(s)--
AstraGIN Proprietary Blend10 mg--

Other ingredients: Natural & Artificial flavors, Citric Acid, Malic Acid, Calcium Silicate, Silicon Dioxide, Sucralose

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Seals/Symbols

BANNED SUBSTANCE TESTED

INFORMED CHOICE.org Trusted by sport

GF

Formulation

Gluten-Free

For performance minded individuals looking for a premium supplement line that is free of FD&C Dyes, fillers, gluten, and other non-desirable ingredients, BSN's CLEAN Elite Athlete Series has you covered with everything you need and nothing you don't.

General Statements

Everything you need, nothing you don't

Creatine Advanced Matrix ~ Supports Muscular Strength^ ~ Supports Muscular Endurance^ ~ Support Performance^

Intended for use in healthy adults as part of a healthy, balanced diet and exercise program. Directions: Mix 1 scoop with 8-10 oz. of cold water or your favorite beverage following a workout. Take two servings per day.

^Based on 2 scoops (5 g Creatine monohydrate) Informed-Choice is a quality assurance program for sports nutrition products. The program certifies that nutritional supplements that bear the Informed-Choice logo have been tested for banned substances by the world class sports anti-doping lab, LGC Limited.

Advanced Matrix

Muscular Strength^ Muscular Endurance^ Performance^

Naturally & Artificially Flavored

Contents sold by weight not volume.

Made in the USA This product contains ingredients of domestic and foreign origin.

Precautions

Warning: Consult your physician before using this product if you are taking any medications or are under a physician's care for a medical condition. Not for use by those under the age of 18, or women that are pregnant, trying to get pregnant, or nursing.

Not for use by those under the age of 18, or women that are pregnant, trying to get pregnant, or nursing.

Storage

Store in a cool dry place away from direct sunlight.

Store in a cool dry place away from direct sunlight.

Brand IP Statement(s)

Finish First.

AstraGIN is a registered trademark of Nuliv Science USA, Inc.

Creatine MagnaPower is a registered trademark of Albion Laboratories, Inc. Covered by U.S. Patent 6,114,379.

BetaPower is a registered trademark of DuPont or its affiliates.

FDA Statement of Identity

Dietary Supplement

General

V.1.263.0315US 6030240

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Clean Creatine Fruit Punch by BSN label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Clean Creatine Fruit Punch label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Clean Creatine Fruit Punch by BSN

These are the 6 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Scoop(s) Dosage formPowder Servings per container50 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Micronized Taurine

Interacts with
173 drugs
1.5 Gram(s) per serving

Taurine is an amino acid your body makes naturally and that you also get from animal foods. It is widely used in energy drinks and sports supplements,...

Micronized Taurine monograph & interactions

Betaine Anhydrous

No known
interactions
1.25 Gram(s) per serving

Betaine anhydrous (also called trimethylglycine) is a compound found in foods like beets, spinach, and whole grains, and is sold as a supplement and a...

Betaine Anhydrous monograph & interactions

Rhodiola rosea extract

Interacts with
1,271 drugs
100 mg per serving

Rhodiola is an herb traditionally used to fight fatigue and help the body cope with stress. Some small studies suggest it may modestly reduce fatigue...

Rhodiola rosea extract monograph & interactions

Creatine Master Blend

No known
interactions
3.5 Gram(s) per serving

Creatine is one of the most studied sports supplements, with solid evidence that it can boost strength and performance during short, high-intensity ac...

Creatine Master Blend monograph & interactions

AstraGIN Proprietary Blend

10 mg per serving

Other (inactive) ingredients: Natural & Artificial flavors, Citric Acid, Malic Acid, Calcium Silicate, Silicon Dioxide, Sucralose. These complete the product’s ingredient list but are not active constituents.

Interaction report

Clean Creatine Fruit Punch by BSN Drug Interactions

Want to check YOUR meds against Clean Creatine Fruit Punch?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
1,418Drugs
6 Major 872 Moderate 540 Minor

Ingredients driving the most interactions

Rhodiola rosea extract 1,271
Astragalus membranaceus extract 208
Panax notoginseng extract 207
micronized Taurine 173

Individual Drug Interactions

The ingredients in Clean Creatine Fruit Punch interact with 1,418 drugs. Click any drug to see the details.

4 of the 6 ingredients in Clean Creatine Fruit Punch interact with drugs. Each result below shows which ingredient is responsible. Rhodiola rosea extract Astragalus membranaceus extract Panax notoginseng extract micronized Taurine

Each ingredient & the kinds of drugs it affects

For each ingredient in Clean Creatine Fruit Punch with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Rhodiola rosea extract10 drug types · 1,271 drugs

Antidiabetes Drugs

Theoretically, taking rhodiola with antidiabetes drugs might increase the risk of hypoglycemia.
In vitro and animal research shows that rhodiola extract can decrease blood glucose due to alpha-glucosidase activity.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, taking rhodiola with antihypertensive drugs might increase the risk of hypotension.
In vitro and animal research shows that rhodiola extract inhibits angiotensin-converting enzyme (ACE) and might lower blood pressure.

Likelihood Possible Evidence D
Cytochrome P450 2C9 (Cyp2C9) Substrates

Theoretically, rhodiola might increase levels of drugs metabolized by CYP2C9.
In vitro research shows that rhodiola inhibits CYP2C9. This effect is highly variable and appears to be dependent on the rhodiola product studied. Also, a clinical study in healthy young males found that taking rhodiola extract 290 mg daily for 14 days reduces the metabolism of losartan, a CYP2C9 substrate, by 21% after 4 hours.

Likelihood Possible Evidence B
Immunosuppressants

Theoretically, rhodiola use might interfere with immunosuppressive therapy.
In vitro and animal research show that rhodiola has immunostimulatory effects.

Likelihood Possible Evidence D
Losartan (Cozaar)

Rhodiola might increase the levels and adverse effects of losartan.
A clinical study in healthy young males found that taking rhodiola extract 290 mg daily for 14 days reduces the metabolism of losartan, a CYP2C9 substrate, by 21% after 4 hours.

Likelihood Probable Evidence B
P-Glycoprotein Substrates

Theoretically, rhodiola might increase levels of P-glycoprotein substrates.
In vitro research shows that rhodiola inhibits P-glycoprotein. Theoretically, using rhodiola with P-glycoprotein substrates might increase drug levels and potentially increase the risk of adverse effects.

Likelihood Possible Evidence D
Antidepressant Drugs

Theoretically, rhodiola might increase the risk of adverse effects when taken with antidepressants.
A review of adverse event reports in Poland identified cases of tachyarrhythmias, myalgia, arthralgia, gum pain, restless leg syndrome, swallowing disorders, and changes in consciousness when rhodiola was taken in combination with paroxetine, escitalopram, fluoxetine, sertraline, trazodone, and/or duloxetine.

Likelihood Possible Evidence D
Cns Depressants

Theoretically, rhodiola might increase the risk of adverse effects when taken with CNS depressants.
A review of adverse event reports in Poland identified cases of excessive sedation, myoclonus, hypotension, and hallucinations when rhodiola was taken with haloperidol, diazepam, or alprazolam.

Likelihood Possible Evidence D
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, rhodiola might increase levels of drugs metabolized by CYP1A2.
In vitro research shows that rhodiola inhibits CYP1A2. This effect is highly variable and appears to be dependent on the rhodiola product studied. However, a clinical study in healthy young males found that taking rhodiola extract 290 mg daily for 14 days does not inhibit the metabolism of caffeine, a CYP1A2 substrate.

Likelihood Possible Evidence B
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, rhodiola might increase levels of drugs metabolized by CYP3A4.
In vitro research shows that rhodiola inhibits CYP3A4. This effect is highly variable and appears to be dependent on the rhodiola product studied. However, a clinical study in healthy young males found that taking rhodiola extract 290 mg daily for 14 days does not inhibit the metabolism of midazolam, a CYP3A4 substrate.

Likelihood Possible Evidence B
Rhodiola rosea extract full monograph & interactions

Astragalus membranaceus extract4 drug types · 208 drugs

Antidiabetes Drugs

Theoretically, taking astragalus with antidiabetes drugs might increase the risk of hypoglycemia.
Clinical research in humans shows that astragalus might have hypoglycemic effects. Theoretically, taking astragalus, especially in combination with other hypoglycemic agents, might increase the risk of hypoglycemia.

Likelihood Probable Evidence A
Cyclophosphamide

Theoretically, astragalus might interfere with cyclophosphamide therapy.
Evidence regarding the effect of astragalus on immunosuppression caused by cyclophosphamide is conflicting. Some animal research suggests that astragalus reverses cyclophosphamide-induced immunosuppression. However, other animal research shows no effect.

Likelihood Possible Evidence D
Immunosuppressants

Theoretically, astragalus might interfere with immunosuppressive therapy.
Astragalus seems to stimulate immune function. Theoretically, taking astragalus might decrease the effects of immunosuppressive therapy.

Likelihood Possible Evidence D
Lithium

Theoretically, astragalus might increase levels and adverse effects of lithium.
Animal research suggests that astragalus has diuretic properties. Theoretically, due to this diuretic effect, astragalus might reduce excretion and increase levels of lithium.

Likelihood Probable Evidence D
Astragalus membranaceus extract full monograph & interactions

Panax notoginseng extract4 drug types · 207 drugs

Aspirin

Theoretically, taking Panax notoginseng concomitantly with aspirin may increase the risk of adverse effects from both products.
Animal research shows that taking Panax notoginseng extract with aspirin increases blood levels of salicylic acid by approximately 50% and blood levels of Panax notoginseng by 75% to 196%. This effect may be due to increased absorption of both products.

Likelihood Possible Evidence D
Caffeine

Theoretically, taking Panax notoginseng may decrease the levels and clinical effects of caffeine.
Animal research shows that administering Panax notoginseng intravenously for 7 days before intraperitoneal injection of caffeine can decrease maximal blood levels of caffeine by 37%. This interaction is attributed to the ability of Panax notoginseng to increase the activity of cytochrome P450 1A2 (CYP1A2) enzymes.

Likelihood Possible Evidence D
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, taking Panax notoginseng might reduce the levels and clinical effects of CYP1A2 substrates.
Animal research shows that administering Panax notoginseng intravenously for 7 days before intraperitoneal injection of caffeine can decrease maximal blood levels of caffeine by 37%. This interaction was attributed to the ability of Panax notoginseng to increase the activity of CYP1A2.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Theoretically, taking Panax notoginseng concomitantly with warfarin may increase the risk of bleeding.
Animal research shows that taking Panax notoginseng concomitantly with warfarin increases plasma warfarin levels, prothrombin time, and international normalized ratio when compared with control. In vitro research also suggests that Panax notoginseng may downregulate expression of cytochrome P450 3A4 enzymes, which may affect warfarin metabolism.

Likelihood Possible Evidence D
Panax notoginseng extract full monograph & interactions

micronized Taurine2 drug types · 173 drugs

Antihypertensive Drugs

Theoretically, taurine might increase the risk of hypotension when taken with antihypertensive drugs.
Some clinical evidence suggests that taurine can reduce both systolic and diastolic blood pressure.

Likelihood Probable Evidence D
Lithium

Theoretically, taurine might reduce excretion and increase plasma levels of lithium.
Taurine is thought to have diuretic properties, which might reduce the excretion of lithium.

Likelihood Probable Evidence D
micronized Taurine full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Clean Creatine Fruit Punch, from the product label.

BSN

See all BSN products
Name
Bio-Engineered Supplements & Nutrition, Inc.
Street Address
975 Meridian Lake Dr.
City
Aurora
State
IL
ZipCode
60504
Phone Number
877-673-3727
Web Address
goBSN.com
Pharmacist Counseling Corner

Clean Creatine Fruit Punch by BSN: Common Questions

Does Clean Creatine Fruit Punch by BSN interact with any medications?
Yes. Based on its ingredients, Clean Creatine Fruit Punch has a known interaction with 1,418 medications, including 6 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Clean Creatine Fruit Punch contains 6 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does creatine actually help with muscle and athletic performance?
Yes, creatine is rated possibly effective for muscle strength and athletic performance in the data we hold. Those are the ingredients in this product with the strongest evidence behind them. Results typically take weeks to show, and you need to stay hydrated.
What are the most common side effects I might notice?
From the creatine content, you may experience dehydration, diarrhea, stomach upset, muscle cramps, or water retention — mostly mild. Taurine can cause constipation or diarrhea. Panax notoginseng may bring on dry mouth, nausea, or insomnia. Most people tolerate it well, but everyone's different.
Can I take this if I have kidney problems?
The data flags caution for people with kidney issues — talk to your doctor or pharmacist before using it. Creatine is filtered through the kidneys, and pre-existing kidney disease changes the safety calculation.
Is it safe to take while pregnant or breastfeeding?
No. Creatine's safety in pregnancy hasn't been established, so the data advises against it. Astragalus, Panax notoginseng, and rhodiola also lack sufficient safety data during pregnancy and breastfeeding. If you're pregnant or nursing, skip this product and talk to your doctor about safer options.
What do these plant extracts do — astragalus, Panax notoginseng, and rhodiola?
The evidence for those ingredients in our data is limited or unclear for most uses. Astragalus is traditionally used for immune support, Panax notoginseng for circulation, and rhodiola for energy and stress — but we don't have strong effectiveness ratings for them in this product.
Why do I need to check my medications with the interaction tool?
This product contains ingredients that can affect how your body processes blood pressure drugs, diabetes medications, blood thinners, and several others. A medication you're on might work less well, or its side effects could get worse. The interaction checker tells you exactly which ones to watch for.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Clean Creatine Fruit Punch is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Clean Creatine Fruit Punch label
Go deeper

The Full Monographs Behind Clean Creatine Fruit Punch’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Taurine

Interacts with 173 drugs

Taurine is an amino acid your body makes naturally and that you also get from animal foods. It is widely used in energy drinks and sports supplements, and short-term use appears generally sa...

Read the full Taurine monograph → Herb & supplement monograph

Betaine Anhydrous

Betaine anhydrous (also called trimethylglycine) is a compound found in foods like beets, spinach, and whole grains, and is sold as a supplement and as a prescription medicine for a rare gen...

Read the full Betaine Anhydrous monograph → Herb & supplement monograph

Rhodiola

Interacts with 1,271 drugs

Rhodiola is an herb traditionally used to fight fatigue and help the body cope with stress. Some small studies suggest it may modestly reduce fatigue and improve mood, but the evidence is li...

Read the full Rhodiola monograph → Herb & supplement monograph

Creatine

Creatine is one of the most studied sports supplements, with solid evidence that it can boost strength and performance during short, high-intensity activities like weightlifting and sprintin...

Read the full Creatine monograph → Herb & supplement monograph

Magnesium

Interacts with 295 drugs

Magnesium is an essential mineral your body needs for muscles, nerves, blood pressure, and many other functions, and supplements are useful for preventing or correcting deficiency. Some othe...

Read the full Magnesium monograph → Herb & supplement monograph

Astragalus

Interacts with 208 drugs

Astragalus is a root used for centuries in traditional Chinese medicine, mainly to support the immune system and help the body cope with stress. While early studies are interesting, strong h...

Read the full Astragalus monograph → Herb & supplement monograph

Panax Notoginseng

Interacts with 207 drugs

Panax notoginseng (sanqi or tienchi ginseng) is a traditional Chinese herb most often used to help with bleeding, bruising, and circulation. Human evidence for these uses is limited and most...

Read the full Panax Notoginseng monograph →
Sources

Sources & How We Checked

Clean Creatine Fruit Punch's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 241 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Creatine 86 references
  1. Koshy KM, Griswold E, Schneeberger EE. Interstitial nephritis in a patient taking creatine. N Engl J Med 1999;340:814-5. PubMed
  2. Vahedi K, Domingo V, Amarenco P, Bousser MG. Ischemic stroke in a sportsman who consumed MaHuang extract and creatine monohydrate for bodybuilding. J Neurol Neurosurg Psychiatr 2000;68:112-3.
  3. Greenhaff P. Renal dysfunction accompanying oral creatine supplements. Lancet 1998;352:233-4. PubMed
  4. Vandenberghe K, Goris M, Van Hecke P, et al. Long-term creatine intake is beneficial to muscle performance during resistance training (abstract). J Appl Physiol 1997;83:2055-63. PubMed
  5. Hultman E, Soderlund K, Timmons JA, et al. Muscle creatine loading in men. J Appl Physiol 1996;81:232-7. PubMed
  6. Pritchard NR, Kalra PA. Renal dysfunction accompanying oral creatine supplements. Lancet 1998;351:1252-3. PubMed
  7. Poortmans JR, Auquier H, Renaut V, et al. Effect of short-term creatine supplementation on renal responses in men (abstract). Eur J Appl Physiol Occup Physiol 1997;76:566-7. PubMed
  8. Poortmans JR, Francaux M. Long-term oral creatine supplementation does not impair renal function in healthy athletes. Med Sci Sports Exerc 1999;31:1108-10. PubMed
  9. Mihic S, MacDonald JR, McKenzie S, Tarnopolsky MA. Acute creatine loading increases fat-free mass, but does not affect blood pressure, plasma creatinine, or CK activity in men and women. Med Sci Sports Exerc 2000;32:291-6. PubMed
  10. Rawson ES, Wehnert ML, Clarkson PM. Effects of 30 days of creatine ingestion in older men. Eur J Appl Physiol Occup Physiol 1999;80:139-44. PubMed
  11. Earnest CP, Almada AL, Mitchell TL. High-performance capillary electrophoresis-pure creatine monohydrate reduces blood lipids in men and women. Clin Sci (Colch) 1996;91:113-8. PubMed
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See these in context on the Rhodiola monograph →

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See these in context on the Magnesium monograph →

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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

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