Collagen Complex Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Collagen Complex against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Collagen Complex is a dietary supplement by Purely Optimal with 5 active ingredients. Its ingredients are commonly taken for skin health and wrinkles, joint pain and osteoarthritis, bone health.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.
HelloPharmacist Scorecard of Collagen Complex by Purely Optimal
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
This product contains 5 active collagen peptide ingredients: bovine collagen peptides, eggshell membrane collagen peptides, hydrolyzed chicken collagen peptides, pure hydrolyzed marine collagen peptides, and avian sternum collagen peptides. These are all hydrolyzed forms — broken down into smaller peptide chains so your body can absorb them more easily.
The inactive ingredient is gelatin capsules.
Does it work?
Moderate evidence
The collagen peptides in this product are possibly effective for aging skin and dry skin based on the evidence we have. For muscle strength, the evidence suggests these ingredients are possibly ineffective.
The data isn't established enough to rate how well they work for acne or athletic performance, so we can't make a claim either way on those.
How safe is it?
Well-documented data
These collagen peptides are generally well tolerated as a dietary protein. Side effects are mild and uncommon, but orally they may cause nausea, upset stomach (dyspepsia), diarrhea, and gas — though this is rare.
If you're pregnant, these ingredients haven't been well studied, so talk with your doctor before using. If you're breastfeeding, there's little safety data available, so caution is advised and you should check with your doctor or pharmacist.
Meds to double-check
No known interactions
No interactions are documented in our data for the collagen peptide ingredients we checked. If you're on any medications, use the search tool on this page to verify your specific drugs.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. No medication interactions are currently documented, and safety information is well characterized.
Collagen Complex is a reasonable option if you're looking to support aging or dry skin — the evidence is modest but positive. Pregnant or breastfeeding women should check with their doctor first.
No medication interactions are documented, but always run your exact drugs through the tool on this page to be certain.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 5 of 5 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Feb 25, 2021.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Collagen Complex, straight from the product label.
| Brand | Purely Optimal |
|---|---|
| Barcode (UPC) | X001Z6OOG5 |
| Net contents | 90 Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Feb 25, 2021 |
| DSLD ID | 243945 |
| Product type | Other Combinations |
| Supplement form | Capsule |
| Dietary claims / uses | Nutrient, All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Collagen Complex by Purely Optimal, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Bovine Collagen Peptides | 0 NP | -- |
| Eggshell Membrane Collagen Peptides | 0 NP | -- |
| Premium Collagen Protein Complex | 1500 mg | -- |
| Hydrolyzed Chicken Collagen Peptides | 0 NP | -- |
| Pure Hydrolyzed Marine Collagen Peptides | 0 NP | -- |
| Avian Sternum Collagen Peptides | 0 NP | -- |
Other ingredients: Gelatin Capsules
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Take three (3) capsules one or more times a day or as directed by your health care professional. For best results take on an empty stomach with an 8 oz. glass of water.
Precautions
Caution: Do not exceed recommended dose.
Pregnant or nursing mothers, children under the age of 18, and individuals with a known medical condition should consult a physician before using this or any dietary supplement.
Pregnant or nursing mothers, children under the age of 18, and individuals with a known medical condition should consult a physician before using this or any dietary supplement. Keep out of reach of children.
Do not use if safety seal is damaged or missing.
Contains: Egg, fish
Storage
Store in a cool, dry place.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Formula
5 types of food source collagen Type I II III V X Hydrolyzed protein
FDA Statement of Identity
Dietary Supplement
Formulation
Supports joint health Revitalizes skin Promotes healthy hair Builds stronger nails
Made with Non GMO ingredients
Contains no added: Milk, tree nuts, wheat, peanuts, soy, shellfish
Seals/Symbols
FDA Registered & Inspected Facility cGMP Facility Good Manufacturing Practice Certification Made in the USA Lab Tested 3rd Party Certified for Purity & Potency
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Collagen Complex by Purely Optimal label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Collagen Complex by Purely Optimal
These are the 5 active ingredients this product is made of. Select any to open its full monograph.
Serving size3 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Premium Collagen Protein Complex
Other (inactive) ingredients: Gelatin Capsules. These complete the product’s ingredient list but are not active constituents.
Collagen Complex by Purely Optimal Drug Interactions
We don’t currently list any known drug interactions for the mapped ingredients in Collagen Complex. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.
Brand information
Manufacturer and brand details for Collagen Complex, from the product label.
Purely Optimal
See all Purely Optimal products- Name
- Purely Optimal Nutrition Inc.
- City
- San Jose
- State
- CA
- ZipCode
- 95132
- Phone Number
- 1-800-738-6018
- Web Address
- www.purelyoptimal.com
Collagen Complex by Purely Optimal: Common Questions
Does Collagen Complex by Purely Optimal interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Will this help my skin?
What are the side effects?
Is it safe if I'm pregnant?
Can I take this while breastfeeding?
What are collagen peptides?
Will it interact with my medications?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Collagen Complex is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Collagen Complex’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Collagen Complex's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 2 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Collagen Peptides 2 references
- Trc T, Bohmová J. Efficacy and tolerance of enzymatic hydrolysed collagen (EHC) vs. glucosamine sulphate (GS) in the treatment of knee osteoarthritis (KOA). Int Orthop. 2011;35(3):341-8. PubMed
- Evans M, Lewis ED, Zakaria N, Pelipyagina T, Guthrie N. A randomized, triple-blind, placebo-controlled, parallel study to evaluate the efficacy of a freshwater marine collagen on skin wrinkles and elasticity. J Cosmet Dermatol. 2021;20(3):825-834. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC