Interactions on record — worth a quick check against your medications. Check your meds →
Dietary supplement

Collagen Enhance Ingredients & Drug Interactions

by ResVitale

Collagen Enhance label
See full label image
Capsule Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Collagen Enhance against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Collagen Enhance is a dietary supplement by ResVitale with 4 active ingredients. Its ingredients are commonly taken for skin hydration and aging, joint comfort and osteoarthritis, dry eyes.Based on those ingredients, 925 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Resveratrol Polyphenol Complex, Chondroitin Sulfate. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Collagen Enhance by ResVitale

Ask about any prescription or over-the-counter medication and we check it for interactions with Collagen Enhance by ResVitale — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Collagen Enhance by ResVitale

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 12, 2026

What’s inside

Partial disclosure
Ingredient Transparency · database check
Partial

Most active ingredients list an amount, but at least one is hidden in a blend or missing.

Why this rating?
  • The label discloses an exact amount for 4 of its 7 active ingredients.
  • “BioCell Collagen” is listed as a grouped ingredient — the label gives one combined amount (1,000 mg) without saying how much of each component you get.
  • “Resveratrol Polyphenol Complex” is a proprietary blend — the label gives one combined amount (400 mg) without saying how much of each component you get.

Collagen Enhance contains 7 ingredients, including hyaluronic acid, trans-resveratrol, hydrolyzed collagen type II, chondroitin sulfate, wildcrafted Japanese knotweed extract, organic French grape, and organic muscadine. These are the active players—hyaluronic acid and collagen peptides support skin hydration and aging, resveratrol and the grape and knotweed extracts bring polyphenol antioxidants, and chondroitin supports joint and eye health.

The product also contains inactive ingredients: vegetarian capsule material, rice bran, and silica for flow and stability.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: skin health and younger-looking appearance.
  • We looked for evidence on: Aging skin, Atopic dermatitis (eczema), Brittle nails, Burns, Cellulite, Corneal abrasion — and 4 related terms.
  • The strongest evidence on file: Hyaluronic Acid is rated "Possibly Effective" for Dry eye (Natural Medicines).
  • Also on file: Collagen Peptides is rated "Possibly Effective" for Aging skin, Dry skin.
  • Also on file: Resveratrol is rated "Insufficient Reliable Evidence To Rate" for Aging skin.

The evidence is mixed and modest across the board. Hyaluronic acid is possibly effective for dry eyes and venous leg ulcers, but there's insufficient evidence for aging skin.

Trans-resveratrol is possibly effective for obesity and hay fever, though possibly ineffective for heart disease and high cholesterol. Hydrolyzed collagen is possibly effective for aging and dry skin, but possibly ineffective for muscle strength.

Chondroitin is possibly effective for cataracts and osteoarthritis. The Japanese knotweed extract and both grape varieties have insufficient or no reliable evidence for the conditions listed in our data—hepatitis, rheumatoid arthritis, wound healing, gout, osteoarthritis, venous insufficiency, and others.

The evidence, ingredient by ingredient Hyaluronic Acid Collagen Peptides Chondroitin Sulfate Resveratrol Hu Zhang Grape

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 5 of the 6 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 6 of 6.
  • General safety write-ups exist for 6 of 6.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Most of the individual ingredients are generally well tolerated at typical doses. Resveratrol and the grape ingredients are generally well tolerated orally, though higher doses of resveratrol may cause digestive upset (diarrhea, loose stools, discomfort).

Collagen peptides rarely cause nausea, dyspepsia, diarrhea, or flatulence. Chondroitin is well tolerated short-term but can cause abdominal pain, bloating, constipation, diarrhea, heartburn, or nausea; rare reports exist of liver injury and skin reactions.

Hyaluronic acid appears well tolerated orally, though the data note that long-term safety of oral supplements is not fully studied. Japanese knotweed has limited human safety data but may cause digestive upset from its emodin content.

During pregnancy, resveratrol and both grape ingredients are rated Likely Safe as foods, but concentrated supplements lack safety data—check with your doctor. Hyaluronic acid, chondroitin, and Japanese knotweed all advise against use in pregnancy and breastfeeding due to insufficient data.

Hydrolyzed collagen has not been well studied in pregnancy or breastfeeding.

Side effects, ingredient by ingredient Hyaluronic Acid Collagen Peptides Chondroitin Sulfate Resveratrol Hu Zhang Grape

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 4 of the 6 matched ingredients can interact with medications — Resveratrol, Grape, Chondroitin Sulfate, Hu Zhang.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; immunosuppressants / transplant drugs.
  • For scale: 926 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking Collagen Enhance, check with your pharmacist or doctor if you take blood thinners or antiplatelet drugs (like warfarin, dabigatran, or aspirin)—resveratrol, the grape extracts, and knotweed all may increase bleeding risk. Also check if you take drugs processed by liver enzymes CYP2C19, CYP1A2, CYP3A4, CYP2D6, or CYP2E1; cyclosporine (an immunosuppressant); carbamazepine (an anti-seizure medication); midazolam (a sedative); or estrogen replacement therapy.

Altogether, these interactions span 926 individual medications.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glancePartially disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Collagen Enhance is a multi-ingredient supplement aimed at skin aging and joint support, but the evidence for most claims is modest or missing. Its biggest concern is medication interactions, especially if you take blood thinners, cyclosporine, carbamazepine, or drugs processed by several liver enzymes.

Talk to your pharmacist or doctor before adding it to your routine, and use the interaction checker on this page to verify your specific medications.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 7 of 7 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Oct 21, 2017.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Collagen Enhance, straight from the product label.

Brand ResVitale
Barcode (UPC) 094922372116
Net contents 120 Veggie Capsule(s)
Market status On market
Date entered into DSLD Oct 21, 2017
DSLD ID 79461
Product type Other Combinations
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Collagen Enhance by ResVitale, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Veggie Capsule(s)
Maximum serving Sizes:
2 Veggie Capsule(s)
Servings per container
60
UPC/BARCODE
094922372116
IngredientAmount% DV
Hyaluronic Acid100 mg--
Trans-Resveratrol100 mg--
Hydrolyzed Collagen Type II600 mg--
Chondroitin Sulfate200 mg--
BioCell Collagen1000 mg--
Resveratrol Polyphenol Complex400 mg--
Wildcrafted Japanese Knotweed extract0 NP--
organic French whole Grape0 NP--
organic Muscadine0 NP--

Other ingredients: Vegetarian Capsule, Rice Bran, Silica

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Vital for smooth, glowing skin, collagen production diminishes with age.

Helps promote and support a younger-looking appearance Helps retain firmer skin to help reduce the visible signs of aging

Smoothes the looks of lines and wrinkles Boosts skin's luminosity, texture & firmness

Formula

A powerful infusion of 1,000 mg of BioCell Collagen with Hyaluronic Acid helps hydrate and plump the foundational layer of skin, while trans-Resveratrol helps boost cellular energy to replenish youthful DNA.

1000 mg Biocell Collagen

BioCell Collagen

1,000 mg of BioCell Collagen with Hyaluronic Acid

Formulation

Gluten free. No artificial colors or flavors.

Precautions

Keep out of reach of children and pets.

Keep out of reach of children and pets. Do not use if seal is broken or missing.

Consult your healthcare professional before using this product if you are pregnant, nursing, on medication or under a doctor’s care.

Brand IP Statement(s)

BioCell Collagen is a registered trademark of BioCell Technology, LLC Newport Beach California, USA (US Patent Pending 6,025,327; 6,323,319; 7,780,841; 7,091,180; 7,799,348 other US and foreign patents pending).

Pure youth activating

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

General

VL1321

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Suggested Use: As a dietary supplement, take 2 capsules daily. For intense use take 4 capsules daily. Product can be taken on an empty stomach, with food or as recommended by your healthcare practitioner

Storage

Store tightly in a cool, dry place.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Collagen Enhance by ResVitale label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Collagen Enhance label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Collagen Enhance by ResVitale

These are the 4 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 Veggie Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

BioCell Collagen

1000 mg per serving

Resveratrol Polyphenol Complex

Interacts with
822 drugs
400 mg per serving

Resveratrol is a plant compound found in red grapes, berries, and peanuts that is popular for heart health, anti-aging, and antioxidant support. While...

Resveratrol Polyphenol Complex monograph & interactions

Other (inactive) ingredients: Vegetarian Capsule, Rice Bran, Silica. These complete the product’s ingredient list but are not active constituents.

Interaction report

Collagen Enhance by ResVitale Drug Interactions

Want to check YOUR meds against Collagen Enhance?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
925Drugs
888 Moderate 37 Minor

Ingredients driving the most interactions

Resveratrol Polyphenol Complex 822
Chondroitin Sulfate 2

Individual Drug Interactions

The ingredients in Collagen Enhance interact with 925 drugs. Click any drug to see the details.

2 of the 4 ingredients in Collagen Enhance interact with drugs. Each result below shows which ingredient is responsible. Resveratrol Polyphenol Complex Chondroitin Sulfate

Each ingredient & the kinds of drugs it affects

For each ingredient in Collagen Enhance with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Resveratrol Polyphenol Complex5 drug types · 822 drugs

Anticoagulant/Antiplatelet Drugs

Resveratrol may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Resveratrol seems to have antiplatelet effects.

Likelihood Possible Evidence D
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, resveratrol might increase levels of drugs metabolized by CYP1A2.
In vitro research shows that resveratrol can inhibit CYP1A2 enzymes. However, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2C19 (Cyp2C19) Substrates

Theoretically, resveratrol might increase levels of drugs metabolized by CYP2C19.
In vitro research shows that resveratrol can inhibit CYP2C19 enzymes. However, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2E1 (Cyp2E1) Substrates

Resveratrol might increase levels of drugs metabolized by CYP2E1.
In vitro research suggests that resveratrol inhibits CYP2E1 isoenzyme. Also, a pharmacokinetic study shows that taking resveratrol 500 mg daily for 10 days prior to taking a single dose of chlorzoxazone 250 mg increases the maximum concentration of chlorzoxazone by about 54%, the area under the curve of chlorzoxazone by about 72%, and the half-life of chlorzoxazone by about 35%. Chlorzoxazone is used as a probe drug for CYP2E1.

Likelihood Probable Evidence B
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, resveratrol might increase levels of drugs metabolized by CYP3A4.
In vitro research shows that resveratrol can inhibit the CYP3A4 enzyme. However, clinical research shows that taking resveratrol 3000 mg daily for 8 weeks does not necessitate dose adjustments to medications metabolized by CYP3A4.

Likelihood Possible Evidence D
Resveratrol Polyphenol Complex full monograph & interactions

Chondroitin Sulfate1 drug type · 2 drugs

Warfarin (Coumadin)

Taking chondroitin in combination with glucosamine might increase the anticoagulant effects of warfarin. However, the effect of chondroitin alone is unclear.
There have been multiple reports of increased international normalized ratio (INR) in patients taking warfarin with glucosamine, with or without chondroitin. The lack of reports with chondroitin alone seem to suggest that the interactions occurring in these reports may have been due to glucosamine. In two individual case reports, glucosamine/chondroitin combinations were associated with a significant increase in INR in patients previously stabilized on warfarin. Additionally, 20 voluntary case reports to the US Food & Drug Administration (FDA) have linked glucosamine plus chondroitin with increased INR, bruising, and bleeding in patients who were also taking warfarin. There have also been 20 additional case reports to the World Health Organization (WHO) that link glucosamine alone, without chondroitin, to increased INR in patients taking warfarin.

Likelihood Unlikely Evidence D
Chondroitin Sulfate full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Collagen Enhance, from the product label.

ResVitale

See all ResVitale products
Phone Number
1-877-787-5454
Web Address
www.resvitale.com
Pharmacist Counseling Corner

Collagen Enhance by ResVitale: Common Questions

Does Collagen Enhance by ResVitale interact with any medications?
Yes. Based on its ingredients, Collagen Enhance has a known interaction with 925 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Collagen Enhance contains 4 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is this safe to take if I'm pregnant or breastfeeding?
It depends on the ingredient. Resveratrol and the grape ingredients are rated Likely Safe as foods but not as concentrated supplements during pregnancy—avoid supplemental forms unless your doctor approves. Hyaluronic acid, chondroitin, and Japanese knotweed all have insufficient safety data and are best avoided in pregnancy and breastfeeding. Hydrolyzed collagen hasn't been well studied in either period. Talk to your doctor or pharmacist for personalized advice.
What's hyaluronic acid in here for?
It's possibly effective for dry eyes and venous leg ulcers, and it supports skin hydration. For aging skin itself, though, the evidence is insufficient. It's generally well tolerated when taken orally, though long-term safety hasn't been fully studied.
Will this actually help my skin or joints?
Hydrolyzed collagen is possibly effective for aging and dry skin. Chondroitin is possibly effective for cataracts and osteoarthritis. Resveratrol, the grapes, and knotweed don't have enough reliable evidence in our data to say they work for skin or joint conditions. Results vary, and the evidence is modest.
What are the most common side effects?
Resveratrol at higher doses may cause diarrhea, loose stools, or digestive discomfort. Collagen peptides rarely cause nausea or digestive upset. Chondroitin can cause abdominal pain, bloating, constipation, diarrhea, or heartburn. The grape and knotweed ingredients are generally well tolerated, though grapes may rarely cause abdominal pain, diarrhea, or headache.
Can I take this with my blood thinner?
Not without checking first. Resveratrol, the grape extracts, and Japanese knotweed all have antiplatelet effects and may increase bleeding risk with blood thinners. There's also a potential interaction between chondroitin and warfarin when combined with glucosamine. Talk to your pharmacist before starting this product if you take any blood thinner or antiplatelet medication.
Is there anything in here that doesn't have interactions documented?
Hyaluronic acid and hydrolyzed collagen type II have no known interactions documented. That said, absence of documented interactions doesn't guarantee none exist—use the medication checker on this page to verify your specific drugs.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Collagen Enhance label
Go deeper

The Full Monographs Behind Collagen Enhance’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Hyaluronic Acid

Hyaluronic acid is a natural substance in the body that helps hold water in the skin, joints, and eyes. Oral and topical products are popular for skin moisture and joint comfort, and the evi...

Read the full Hyaluronic Acid monograph → Herb & supplement monograph

Collagen Peptides

Collagen peptides are a well-absorbed form of protein that may modestly improve skin elasticity and joint comfort for some people, though evidence is still developing and results vary. They...

Read the full Collagen Peptides monograph → Herb & supplement monograph

Chondroitin Sulfate

Interacts with 2 drugs

Chondroitin sulfate is a naturally occurring building block of cartilage that is widely taken, often with glucosamine, for osteoarthritis joint pain. The evidence is mixed—some people report...

Read the full Chondroitin Sulfate monograph → Herb & supplement monograph

Resveratrol

Interacts with 822 drugs

Resveratrol is a plant compound found in red grapes, berries, and peanuts that is popular for heart health, anti-aging, and antioxidant support. While lab and animal studies are promising, s...

Read the full Resveratrol monograph → Herb & supplement monograph

Hu Zhang

Interacts with 826 drugs

Hu Zhang (Japanese knotweed root) is a traditional Chinese herb that is one of the richest natural sources of resveratrol and emodin. Some lab and early human research looks interesting for...

Read the full Hu Zhang monograph → Herb & supplement monograph

Grape

Interacts with 910 drugs

Grapes and grape products like grape seed extract contain antioxidant compounds such as resveratrol and proanthocyanidins that may support heart and blood vessel health. While the food is he...

Read the full Grape monograph →
Sources

Sources & How We Checked

Collagen Enhance's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 105 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Hyaluronic Acid 4 references
  1. Park Y, Song JS, Choi CY, Yoon KC, Lee HK, Kim HS. A randomized multicenter study comparing 0.1%, 0.15%, and 0.3% sodium hyaluronate with 0.05% cyclosporine in the treatment of dry eye. J Ocul Pharmacol Ther. 2017;33(2):66-72. PubMed
  2. U.S. Food and Drug Administration. Do Not Use Needle-Free Devices for Injection of Dermal Fillers - FDA Safety Communication. October 8, 2021. Available at: https://www.fda.gov/medical-devices/safety-communications/do-not-use-needle-free-devices-injection
  3. Disphanurat W, Srisantithum B. Efficacy and safety of 0.15% isobutylamido thiazolyl resorcinol combined with hyaluronic acid vs 0.15% isobutylamido thiazolyl resorcinol or hyaluronic acid alone in melasma treatment: A randomized evaluator-blind trial. J C PubMed
  4. Humbert P, Mikosinki J, Benchikhi H, Allaert FA. Efficacy and safety of a gauze pad containing hyaluronic acid in treatment of leg ulcers of venous or mixed origin: a double-blind, randomised, controlled trial. Int Wound J 2013;10(2):159-66. PubMed

See these in context on the Hyaluronic Acid monograph →

Resveratrol 24 references
  1. Soleas GJ, Diamandis EP, Goldberg DM. Resveratrol: a molecule whose time has come? And gone? Clin Biochem 1997;30:91-113.
  2. Pace-Asciak CR, Rounova O, Hahn SE, et al. Wines and grape juices as modulators of platelet aggregation in healthy human subjects. Clin Chim Acta 1996;246:163-82. PubMed
  3. Bertelli AA, Giovannini L, Bernini W, et al. Antiplatelet activity of cis-resveratrol. Drugs Exp Clin Res 1996;22:61-3.
  4. Pace-Asciak CR, Hahn S, Diamandis EP, et al. The red wine phenolics trans-resveratrol and quercetin block human platelet aggregation and eicosanoid synthesis: implications for protection against coronary heart disease. Clin Chim Acta 1995;235:207-19.
  5. Bertelli A, Bertelli AA, Gozzini A, Giovannini L. Plasma and tissue resveratrol concentrations and pharmacological activity. Drugs Exp Clin Res 1998;24:133-8.
  6. Bertelli AA, Giovannini L, Giannessi D, et al. Antiplatelet activity of synthetic and natural resveratrol in red wine. Int J Tissue React 1995;17:1-3.
  7. Piver B, Berthou F, Dreano Y, Lucas D. Inhibition of CYP3A, CYP1A and CYP2E1 activities by resveratrol and other non volatile red wine components. Toxicol Lett 2001;125:83-91. PubMed
  8. Chang, T. K., Chen, J., and Lee, W. B. Differential inhibition and inactivation of human CYP1 enzymes by trans-resveratrol: evidence for mechanism-based inactivation of CYP1A2. J.Pharmacol.Exp.Ther. 2001;299(3):874-882.
  9. Dobrydneva, Y., Williams, R. L., and Blackmore, P. F. trans-Resveratrol inhibits calcium influx in thrombin-stimulated human platelets. Br.J.Pharmacol. 1999;128(1):149-157.
  10. Kirk, R. I., Deitch, J. A., Wu, J. M., and Lerea, K. M. Resveratrol decreases early signaling events in washed platelets but has little effect on platalet in whole food. Blood Cells Mol.Dis. 2000;26(2):144-150.
  11. Zbikowska, H. M. and Olas, B. Antioxidants with carcinostatic activity (resveratrol, vitamin E and selenium) in modulation of blood platelet adhesion. J Physiol Pharmacol. 2000;51(3):513-520.
  12. Olas, B., Wachowicz, B., Saluk-Juszczak, J., and Zielinski, T. Effect of resveratrol, a natural polyphenolic compound, on platelet activation induced by endotoxin or thrombin. Thromb.Res 8-15-2002;107(3-4):141-145. PubMed
  13. Yu, C., Shin, Y. G., Kosmeder, J. W., Pezzuto, J. M., and van Breemen, R. B. Liquid chromatography/tandem mass spectrometric determination of inhibition of human cytochrome P450 isozymes by resveratrol and resveratrol-3-sulfate. Rapid Commun.Mass Spectro PubMed
  14. Ma, Z. H. and Ma, Q. Y. Resveratrol: a medical drug for acute pancreatitis. World J Gastroenterol. 6-7-2005;11(21):3171-3174. PubMed
  15. la, Porte C., Voduc, N., Zhang, G., Seguin, I., Tardiff, D., Singhal, N., and Cameron, D. W. Steady-State pharmacokinetics and tolerability of trans-resveratrol 2000 mg twice daily with food, quercetin and alcohol (ethanol) in healthy human subjects. Cli PubMed
  16. Brown, V. A., Patel, K. R., Viskaduraki, M., Crowell, J. A., Perloff, M., Booth, T. D., Vasilinin, G., Sen, A., Schinas, A. M., Piccirilli, G., Brown, K., Steward, W. P., Gescher, A. J., and Brenner, D. E. Repeat dose study of the cancer chemopreventive
  17. Pendurthi, U. R., Williams, J. T., and Rao, L. V. Resveratrol, a polyphenolic compound found in wine, inhibits tissue factor expression in vascular cells : A possible mechanism for the cardiovascular benefits associated with moderate consumption of wine. PubMed
  18. Chachay VS, Macdonald GA, Martin JH, Whitehead JP, O'Moore-Sullivan TM, Lee P, Franklin M, Klein K, Taylor PJ, Ferguson M, Coombes JS, Thomas GP, Cowin GJ, Kirkpatrick CM, Prins JB, Hickman IJ. Resveratrol does not benefit patients with nonalcoholic fatty
  19. Bedada SK, Neerati P. Resveratrol Pretreatment Affects CYP2E1 Activity of Chlorzoxazone in Healthy Human Volunteers. Phytother Res. 2016;30(3):463-8. PubMed
  20. Lin CT, Sun XY, Lin AX. Supplementation with high-dose trans-resveratrol improves ultrafiltration in peritoneal dialysis patients: a prospective, randomized, double-blind study. Ren Fail. 2016;38(2):214-21. PubMed
  21. Li Q, Yang G, Xu H, Tang S, Lee WY. Effects of resveratrol supplementation on bone quality: a systematic review and meta-analysis of randomized controlled trials. BMC Complement Med Ther 2021;21(1):214. PubMed
  22. McCreary MR, Schnell PM, Rhoda DA. Randomized double-blind placebo-controlled proof-of-concept trial of resveratrol for outpatient treatment of mild coronavirus disease (COVID-19). Sci Rep 2022;12(1):10978. PubMed
  23. Abdelhaleem IA, Brakat AM, Adayel HM, Asla MM, Rizk MA, Aboalfetoh AY. The effects of resveratrol on glycemic control and cardiometabolic parameters in patients with T2DM: A systematic review and meta-analysis. Med Clin (Barc) 2022;158(12):576-585. PubMed
  24. Badaoui A. Allergic contact dermatitis to resveratrol and Scutellaria baicalensis root extract in a cosmetic product. Contact Dermatitis 2022.

See these in context on the Resveratrol monograph →

Collagen Peptides 2 references
  1. Trc T, Bohmová J. Efficacy and tolerance of enzymatic hydrolysed collagen (EHC) vs. glucosamine sulphate (GS) in the treatment of knee osteoarthritis (KOA). Int Orthop. 2011;35(3):341-8. PubMed
  2. Evans M, Lewis ED, Zakaria N, Pelipyagina T, Guthrie N. A randomized, triple-blind, placebo-controlled, parallel study to evaluate the efficacy of a freshwater marine collagen on skin wrinkles and elasticity. J Cosmet Dermatol. 2021;20(3):825-834. PubMed

See these in context on the Collagen Peptides monograph →

Chondroitin Sulfate 22 references
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Hu Zhang 19 references
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Grape 34 references
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  12. de Lange, D. W., Scholman, W. L., Kraaijenhagen, R. J., Akkerman, J. W., and van de Wiel, A. Alcohol and polyphenolic grape extract inhibit platelet adhesion in flowing blood. Eur.J Clin.Invest 2004;34(12):818-824. PubMed
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