Colon Pro Health Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Colon Pro Health against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Colon Pro Health is a dietary supplement by Logos Nutritionals with 10 active ingredients. Its ingredients are commonly taken for digestive health and balance, diarrhea (including antibiotic-related), vaginal yeast and bacterial infections.Based on those ingredients, 2,135 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Glucomannan, Powder, Aloe Vera, Powder, Lactobacillus acidophilus. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Colon Pro Health by Logos Nutritionals
Ask about any prescription or over-the-counter medication and we check it for interactions with Colon Pro Health by Logos Nutritionals — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Colon Pro Health by Logos Nutritionals
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
Colon Pro Health contains 10 ingredients, including a proprietary blend with live Lactobacillus acidophilus (a beneficial bacteria), apple pectin, aloe vera powder, black walnut powder, and glucomannan, plus flaxseed, oat bran, psyllium husk, bentonite clay, and prune powder. The first six ingredients are listed individually; the others are part of the proprietary blend or checked separately.
Inactive ingredients include bovine gelatin (the capsule), magnesium stearate, and silicon dioxide.
Does it work?
Moderate evidence
Lactobacillus acidophilus is rated possibly effective for irritable bowel syndrome (IBS), Helicobacter pylori infection, antibiotic-associated diarrhea, and bacterial vaginosis, but possibly ineffective for atopic disease. There isn't enough evidence to rate it for acute respiratory distress syndrome.
Apple pectin is possibly effective for high cholesterol but has insufficient evidence for prediabetes or radiation exposure. Aloe vera is possibly effective for acne, obesity, diabetes, psoriasis, burns, and constipation.
Black walnut has insufficient evidence for heart disease or wound healing. Glucomannan is possibly effective for constipation, diabetes, and high cholesterol, with insufficient evidence for high blood pressure.
For flaxseed, oat bran, psyllium husk, and bentonite clay, effectiveness data are not on file.
How safe is it?
Well-documented data
Lactobacillus acidophilus is generally well tolerated in healthy adults and children. A small number of trial participants reported gastrointestinal side effects like abdominal pain, bloating, flatulence, and diarrhea, though these were uncommon.
Rare cases of serious infections (bacteremia, sepsis, abscess) have been reported, usually in patients whose immune systems were already compromised. Apple pectin is generally well tolerated; most common side effects are diarrhea, gas, and mild cramps.
Rare allergic reactions including anaphylaxis have been reported in sensitive individuals. Aloe vera powder carries the greatest caution — oral aloe latex may cause abdominal pain, cramps, and diarrhea, and long-term use can lead to potassium loss and muscle weakness.
Black walnut is acceptably used short-term but has limited long-term safety data; the leaf, bark, and hull contain tannins that may cause gastrointestinal upset and skin irritation. Glucomannan is well tolerated with adequate water but can cause bloating, gas, diarrhea, nausea, and rarely, choking or intestinal blockage if not taken properly.
Pregnancy data: aloe latex should be avoided in pregnancy; black walnut is best avoided; glucomannan, pectin, and Lactobacillus acidophilus lack sufficient pregnancy safety data — ask your doctor. For breastfeeding: aloe should be avoided; glucomannan and black walnut have limited data — check with your healthcare provider.
Meds to double-check
Major interaction found
Before taking Colon Pro Health, double-check with your pharmacist if you take: digoxin (a heart medication) — aloe creates a Major interaction; blood thinners or warfarin; diabetes medications; diuretics; antibiotics; lovastatin; tetracycline antibiotics; or stimulant laxatives. The product may also interact with other oral medications due to glucomannan's effects on absorption.
Separate antibiotics from this product by at least a few hours if possible.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. Major medication interactions have been identified, and safety information is well characterized.
Colon Pro Health may help with constipation, IBS, or cholesterol if you're not taking certain medications. If you take digoxin, antibiotics, warfarin, diabetes drugs, diuretics, or lovastatin, you'll need to discuss this product with your pharmacist or doctor first — interactions could affect how your medications work or your safety.
Even if you're not on those drugs, the aloe vera content means you should check your full medication list before starting.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 5 of 10 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Aug 22, 2025.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Colon Pro Health, straight from the product label.
| Brand | Logos Nutritionals |
|---|---|
| Barcode (UPC) | 850045673161 |
| Net contents | 90 Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Aug 22, 2025 |
| DSLD ID | 335702 |
| Product type | Other Combinations |
| Supplement form | Capsule |
| Dietary claims / uses | Nutrient, All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Women (not pregnant or lactating) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Colon Pro Health by Logos Nutritionals, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Proprietary Blend | 2250 mg | -- |
| Lactobacillus acidophilus | 0 NP | -- |
| Flaxseed, Powder | 0 NP | -- |
| Oat Bran, Powder | 0 NP | -- |
| Psyllium Husk | 0 NP | -- |
| Bentonite Clay | 0 NP | -- |
| Apple Pectin, Powder | 0 NP | -- |
| Aloe Vera, Powder | 0 NP | -- |
| Black Walnut, Powder | 0 NP | -- |
| Glucomannan, Powder | 0 NP | -- |
| Prune, Powder | 0 NP | -- |
Other ingredients: Bovine Gelatin, Magnesium Stearate, Silicon Dioxide
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula
Gentle maintenance formula with cleansing herbs, probiotics, fiber and soothing agents to help remove buildup of wastes and maintain regularity.
Formulation
Unlike our seven day cleanse (MagnifiCleanse), this product may be taken on a daily regimen for as long as desired.
We back our products with an unconditional satisfaction guarantee!
Gentle maintenance cleanse
Purity Potency Renew your health, naturally
Non-GMO
Dietary Supplement
Suggested/Recommended/Usage/Directions
Suggested use: Take 3 capsules daily with 8 ounces of water or as directed by a healthcare professional.
Precautions
This product is not intended for pregnant or nursing mothers or children under 18 years of age.
This product is not intended for pregnant or nursing mothers or children under 18 years of age.
Do not use if you have abdominal pain, diarrhea or loose stools. Rectal bleeding, abdominal cramping, and/or failure to have a bowel movement after the use of a laxative formula may be an indication of a more serious condition.
Rectal bleeding, abdominal cramping, and/or failure to have a bowel movement after the use of a laxative formula may be an indication of a more serious condition. Should this occur, or if you have a known medical condition and are taking medication, consult your physician before taking this or any dietary supplement.
This product is manufactured and packaged in a facility which may also process milk, soy, wheat, egg, peanuts, tree nuts, fish and crustacean shellfish.
Allergen warning: Contains tree nuts (black walnut).
Keep out of the reach of children.
Do not use if safety seal is damaged or missing.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
General Statements
Questions or comments - call 800-556-5530 or visit our website: www.logosnutritionals.com
Brand IP Statement(s)
Copyright 2022 Logos
Seals/Symbols
Sourced from A GMP Certified Facility Good manufacturing practice Quality assured Lab Verified 3rd Party Tested
Storage
Store in a cool, dry place.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Colon Pro Health by Logos Nutritionals label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Colon Pro Health by Logos Nutritionals
These are the 10 active ingredients this product is made of. Select any to open its full monograph.
Serving size3 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Proprietary Blend
- › Lactobacillus acidophilus
- › Flaxseed, Powder
- › Oat Bran, Powder
- › Psyllium Husk
- › Bentonite Clay
- › Apple Pectin, Powder
- › Aloe Vera, Powder
- › Black Walnut, Powder
- › Glucomannan, Powder
- › Prune, Powder
Other (inactive) ingredients: Bovine Gelatin, Magnesium Stearate, Silicon Dioxide. These complete the product’s ingredient list but are not active constituents.
Colon Pro Health by Logos Nutritionals Drug Interactions
HelloPharmacist Interaction Report
Colon Pro Health by Logos Nutritionals contains several ingredients with documented interactions.
The most serious concern is aloe vera powder, which carries a Major-severity interaction with digoxin (Lanoxin), a heart medication. Overuse of aloe latex can deplete potassium and increase the risk of heart drug toxicity.
Read the full breakdown — every affected drug type, severity by severity
Aloe vera also has Moderate-severity interactions with blood thinners (anticoagulants/antiplatelet drugs) and warfarin, raising bleeding risk; diabetes medications, which may lower blood sugar too much; diuretics, which could worsen potassium loss; and stimulant laxatives, which may compound fluid and electrolyte loss. It also has a Minor interaction with CYP1A2 substrates, a group of drugs your liver processes.
Lactobacillus acidophilus carries a Moderate interaction with antibiotic drugs — antibiotics may kill the beneficial bacteria in the supplement, reducing its effectiveness. Apple pectin has Moderate interactions with lovastatin, tetracycline antibiotics, and digoxin, potentially lowering their absorption and effectiveness.
Glucomannan, also included, has a Moderate interaction with oral drugs in general due to its bulking effects on absorption.
We could not check flaxseed, oat bran, psyllium husk, bentonite clay, or prune powder — we hold no interaction data for them. Altogether, these interactions span 2,116 individual medications.
Check your exact medications with the search tool below before starting this product.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Colon Pro Health?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Colon Pro Health interact with 2,135 drugs. Click any drug to see the details.
4 of the 10 ingredients in Colon Pro Health interact with drugs. Each result below shows which ingredient is responsible. Glucomannan, Powder Aloe Vera, Powder Lactobacillus acidophilus Apple Pectin, Powder
DigoxinDigitek, Lanoxicaps, Lanoxin
How Digoxin interacts with Colon Pro Health — through 3 ingredients. Tap an ingredient for the detail:
Aloe Vera, PowderDigoxin (lanoxin) Major
Interaction Summary
Theoretically, aloe latex might increase the risk of adverse effects when taken with cardiac glycosides.
Read the full Aloe Vera, Powder + Digoxin interactionGlucomannan, PowderOral Drugs Moderate
Interaction Summary
Theoretically, glucomannan may decrease absorption of drugs taken orally.
Read the full Glucomannan, Powder + Digoxin interactionApple Pectin, PowderDigoxin (lanoxin) Moderate
Interaction Summary
Theoretically, pectin might reduce the absorption of digoxin, potentially decreasing its effectiveness.
Read the full Apple Pectin, Powder + Digoxin interaction"phentolamineOraVerse, Rogitine, Ryzumvi
How "phentolamine interacts with Colon Pro Health — through 1 ingredient. Tap an ingredient for the detail:
Glucomannan, PowderOral Drugs Moderate
Interaction Summary
Theoretically, glucomannan may decrease absorption of drugs taken orally.
Read the full Glucomannan, Powder + "phentolamine interaction6-mercaptopurinePurinethol
How 6-mercaptopurine interacts with Colon Pro Health — through 1 ingredient. Tap an ingredient for the detail:
Glucomannan, PowderOral Drugs Moderate
Interaction Summary
Theoretically, glucomannan may decrease absorption of drugs taken orally.
Read the full Glucomannan, Powder + 6-mercaptopurine interactionAbacavirZiagen
How Abacavir interacts with Colon Pro Health — through 1 ingredient. Tap an ingredient for the detail:
Glucomannan, PowderOral Drugs Moderate
Interaction Summary
Theoretically, glucomannan may decrease absorption of drugs taken orally.
Read the full Glucomannan, Powder + Abacavir interactionAbacavir Sulfate, Dolutegravir, LamivudineTriumeq
How Abacavir Sulfate, Dolutegravir, Lamivudine interacts with Colon Pro Health — through 1 ingredient. Tap an ingredient for the detail:
Glucomannan, PowderOral Drugs Moderate
Interaction Summary
Theoretically, glucomannan may decrease absorption of drugs taken orally.
Read the full Glucomannan, Powder + Abacavir Sulfate, Dolutegravir, Lamivudine interactionAbacavir, LamivudineEpzicom
How Abacavir, Lamivudine interacts with Colon Pro Health — through 1 ingredient. Tap an ingredient for the detail:
Glucomannan, PowderOral Drugs Moderate
Interaction Summary
Theoretically, glucomannan may decrease absorption of drugs taken orally.
Read the full Glucomannan, Powder + Abacavir, Lamivudine interactionAbciximabReoPro
How Abciximab interacts with Colon Pro Health — through 2 ingredients. Tap an ingredient for the detail:
Aloe Vera, PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Aloe Vera, Powder + Abciximab interactionGlucomannan, PowderOral Drugs Moderate
Interaction Summary
Theoretically, glucomannan may decrease absorption of drugs taken orally.
Read the full Glucomannan, Powder + Abciximab interactionAbemaciclibVerzenio
How Abemaciclib interacts with Colon Pro Health — through 1 ingredient. Tap an ingredient for the detail:
Glucomannan, PowderOral Drugs Moderate
Interaction Summary
Theoretically, glucomannan may decrease absorption of drugs taken orally.
Read the full Glucomannan, Powder + Abemaciclib interactionAbiraterone
How Abiraterone interacts with Colon Pro Health — through 1 ingredient. Tap an ingredient for the detail:
Glucomannan, PowderOral Drugs Moderate
Interaction Summary
Theoretically, glucomannan may decrease absorption of drugs taken orally.
Read the full Glucomannan, Powder + Abiraterone interactionAbiraterone AcetateYonsa, Zytiga
How Abiraterone Acetate interacts with Colon Pro Health — through 1 ingredient. Tap an ingredient for the detail:
Glucomannan, PowderOral Drugs Moderate
Interaction Summary
Theoretically, glucomannan may decrease absorption of drugs taken orally.
Read the full Glucomannan, Powder + Abiraterone Acetate interactionAbrocitinibCibinqo
How Abrocitinib interacts with Colon Pro Health — through 2 ingredients. Tap an ingredient for the detail:
Glucomannan, PowderOral Drugs Moderate
Interaction Summary
Theoretically, glucomannan may decrease absorption of drugs taken orally.
Read the full Glucomannan, Powder + Abrocitinib interactionAloe Vera, PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Aloe Vera, Powder + Abrocitinib interactionAcalabrutinibCalquence
How Acalabrutinib interacts with Colon Pro Health — through 1 ingredient. Tap an ingredient for the detail:
Glucomannan, PowderOral Drugs Moderate
Interaction Summary
Theoretically, glucomannan may decrease absorption of drugs taken orally.
Read the full Glucomannan, Powder + Acalabrutinib interactionAcamprosateCampral
How Acamprosate interacts with Colon Pro Health — through 1 ingredient. Tap an ingredient for the detail:
Glucomannan, PowderOral Drugs Moderate
Interaction Summary
Theoretically, glucomannan may decrease absorption of drugs taken orally.
Read the full Glucomannan, Powder + Acamprosate interactionAcarboseGlucobay, Prandase, Precose
How Acarbose interacts with Colon Pro Health — through 2 ingredients. Tap an ingredient for the detail:
Aloe Vera, PowderAntidiabetes Drugs Moderate
Interaction Summary
Aloe might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Aloe Vera, Powder + Acarbose interactionGlucomannan, PowderOral Drugs Moderate
Interaction Summary
Theoretically, glucomannan may decrease absorption of drugs taken orally.
Read the full Glucomannan, Powder + Acarbose interactionAcebutololRhotral, Sectral
How Acebutolol interacts with Colon Pro Health — through 1 ingredient. Tap an ingredient for the detail:
Glucomannan, PowderOral Drugs Moderate
Interaction Summary
Theoretically, glucomannan may decrease absorption of drugs taken orally.
Read the full Glucomannan, Powder + Acebutolol interactionAcenocoumarolSintrom
How Acenocoumarol interacts with Colon Pro Health — through 2 ingredients. Tap an ingredient for the detail:
Aloe Vera, PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Aloe Vera, Powder + Acenocoumarol interactionGlucomannan, PowderOral Drugs Moderate
Interaction Summary
Theoretically, glucomannan may decrease absorption of drugs taken orally.
Read the full Glucomannan, Powder + Acenocoumarol interactionAcepromazineAtravet
How Acepromazine interacts with Colon Pro Health — through 1 ingredient. Tap an ingredient for the detail:
Glucomannan, PowderOral Drugs Moderate
Interaction Summary
Theoretically, glucomannan may decrease absorption of drugs taken orally.
Read the full Glucomannan, Powder + Acepromazine interactionAcetaminophenChildren's Tylenol, Children's Tylenol Meltaways, Tylenol, Tylenol Ex Strength
How Acetaminophen interacts with Colon Pro Health — through 2 ingredients. Tap an ingredient for the detail:
Glucomannan, PowderOral Drugs Moderate
Interaction Summary
Theoretically, glucomannan may decrease absorption of drugs taken orally.
Read the full Glucomannan, Powder + Acetaminophen interactionAloe Vera, PowderCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, aloe might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Aloe Vera, Powder + Acetaminophen interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Colon Pro Health — through 2 ingredients. Tap an ingredient for the detail:
Aloe Vera, PowderCytochrome P450 1a2 (cyp1a2) Substrates, Anticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, aloe might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Aloe Vera, Powder + Acetaminophen, Aspirin interactionGlucomannan, PowderOral Drugs Moderate
Interaction Summary
Theoretically, glucomannan may decrease absorption of drugs taken orally.
Read the full Glucomannan, Powder + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Colon Pro Health — through 2 ingredients. Tap an ingredient for the detail:
Aloe Vera, PowderAnticoagulant/antiplatelet Drugs, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Aloe Vera, Powder + Acetaminophen, Aspirin, Caffeine interactionGlucomannan, PowderOral Drugs Moderate
Interaction Summary
Theoretically, glucomannan may decrease absorption of drugs taken orally.
Read the full Glucomannan, Powder + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, Brompheniramine, PhenylpropanolamineDimetapp Cold and Flu
How Acetaminophen, Brompheniramine, Phenylpropanolamine interacts with Colon Pro Health — through 2 ingredients. Tap an ingredient for the detail:
Glucomannan, PowderOral Drugs Moderate
Interaction Summary
Theoretically, glucomannan may decrease absorption of drugs taken orally.
Read the full Glucomannan, Powder + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionAloe Vera, PowderCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, aloe might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Aloe Vera, Powder + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionAcetaminophen, ButalbitalAxocet, Bancap, Bucet, Butex Forte, Esgic CF, Orbivan CF +5 more
How Acetaminophen, Butalbital interacts with Colon Pro Health — through 2 ingredients. Tap an ingredient for the detail:
Glucomannan, PowderOral Drugs Moderate
Interaction Summary
Theoretically, glucomannan may decrease absorption of drugs taken orally.
Read the full Glucomannan, Powder + Acetaminophen, Butalbital interactionAloe Vera, PowderCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, aloe might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Aloe Vera, Powder + Acetaminophen, Butalbital interactionAcetaminophen, Butalbital, CaffeineEsgic, Esgic Plus, Fiogesic, Fioricet, Repan, Tecnal +1 more
How Acetaminophen, Butalbital, Caffeine interacts with Colon Pro Health — through 2 ingredients. Tap an ingredient for the detail:
Glucomannan, PowderOral Drugs Moderate
Interaction Summary
Theoretically, glucomannan may decrease absorption of drugs taken orally.
Read the full Glucomannan, Powder + Acetaminophen, Butalbital, Caffeine interactionAloe Vera, PowderCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, aloe might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Aloe Vera, Powder + Acetaminophen, Butalbital, Caffeine interactionAcetaminophen, Butalbital, Caffeine, CodeineEsgic with Codeine, Fioricet w/ Codeine
How Acetaminophen, Butalbital, Caffeine, Codeine interacts with Colon Pro Health — through 2 ingredients. Tap an ingredient for the detail:
Glucomannan, PowderOral Drugs Moderate
Interaction Summary
Theoretically, glucomannan may decrease absorption of drugs taken orally.
Read the full Glucomannan, Powder + Acetaminophen, Butalbital, Caffeine, Codeine interactionAloe Vera, PowderCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, aloe might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Aloe Vera, Powder + Acetaminophen, Butalbital, Caffeine, Codeine interactionAcetaminophen, Butalbital, CodeineBancap w/ Codeine
How Acetaminophen, Butalbital, Codeine interacts with Colon Pro Health — through 2 ingredients. Tap an ingredient for the detail:
Glucomannan, PowderOral Drugs Moderate
Interaction Summary
Theoretically, glucomannan may decrease absorption of drugs taken orally.
Read the full Glucomannan, Powder + Acetaminophen, Butalbital, Codeine interactionAloe Vera, PowderCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, aloe might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Aloe Vera, Powder + Acetaminophen, Butalbital, Codeine interactionAcetaminophen, Butalbital, Codeine PhosphatePhrenilin #3
How Acetaminophen, Butalbital, Codeine Phosphate interacts with Colon Pro Health — through 2 ingredients. Tap an ingredient for the detail:
Glucomannan, PowderOral Drugs Moderate
Interaction Summary
Theoretically, glucomannan may decrease absorption of drugs taken orally.
Read the full Glucomannan, Powder + Acetaminophen, Butalbital, Codeine Phosphate interactionAloe Vera, PowderCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, aloe might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Aloe Vera, Powder + Acetaminophen, Butalbital, Codeine Phosphate interactionAcetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, PhenylephrineHycomine Compound
How Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interacts with Colon Pro Health — through 2 ingredients. Tap an ingredient for the detail:
Glucomannan, PowderOral Drugs Moderate
Interaction Summary
Theoretically, glucomannan may decrease absorption of drugs taken orally.
Read the full Glucomannan, Powder + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionAloe Vera, PowderCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, aloe might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Aloe Vera, Powder + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionAcetaminophen, Caffeine, CodeineGesic C15, Gesic C30, Gesic C8, Lenoltec 1, Lenoltec 2, Lenoltec 3 +1 more
How Acetaminophen, Caffeine, Codeine interacts with Colon Pro Health — through 2 ingredients. Tap an ingredient for the detail:
Glucomannan, PowderOral Drugs Moderate
Interaction Summary
Theoretically, glucomannan may decrease absorption of drugs taken orally.
Read the full Glucomannan, Powder + Acetaminophen, Caffeine, Codeine interactionAloe Vera, PowderCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, aloe might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Aloe Vera, Powder + Acetaminophen, Caffeine, Codeine interactionAcetaminophen, Caffeine, Codeine, SalicylamideCodalan No.1, Codalan No.2, Codalan No.3
How Acetaminophen, Caffeine, Codeine, Salicylamide interacts with Colon Pro Health — through 2 ingredients. Tap an ingredient for the detail:
Glucomannan, PowderOral Drugs Moderate
Interaction Summary
Theoretically, glucomannan may decrease absorption of drugs taken orally.
Read the full Glucomannan, Powder + Acetaminophen, Caffeine, Codeine, Salicylamide interactionAloe Vera, PowderCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, aloe might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Aloe Vera, Powder + Acetaminophen, Caffeine, Codeine, Salicylamide interactionAcetaminophen, Caffeine, DihydrocodeineDHC Plus, Panlor DC, Panlor SS
How Acetaminophen, Caffeine, Dihydrocodeine interacts with Colon Pro Health — through 2 ingredients. Tap an ingredient for the detail:
Glucomannan, PowderOral Drugs Moderate
Interaction Summary
Theoretically, glucomannan may decrease absorption of drugs taken orally.
Read the full Glucomannan, Powder + Acetaminophen, Caffeine, Dihydrocodeine interactionAloe Vera, PowderCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, aloe might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Aloe Vera, Powder + Acetaminophen, Caffeine, Dihydrocodeine interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Colon Pro Health with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Glucomannan, Powder
Oral Drugs
Theoretically, glucomannan may decrease absorption of drugs taken orally.
Due to its viscosity and bulking effects, there is concern that glucomannan can decrease the absorption of oral drugs. A small clinical study in healthy volunteers shows that taking glyburide 2.5 mg plus glucomannan 3.9 grams with breakfast reduces plasma levels of glyburide when compared with breakfast and glyburide alone. In addition, animal research demonstrates this effect on amoxicillin, but shows increased absorption of metronidazole. This mouse model also demonstrates that metronidazole elimination is prolonged, but amoxicillin elimination is enhanced by 38%; glucomannan may also affect the distribution of some drugs. To avoid changes in absorption, take glucomannan 30-60 minutes after taking oral drugs.
Aloe Vera, Powder
Digoxin (Lanoxin)
Theoretically, aloe latex might increase the risk of adverse effects when taken with cardiac glycosides.
Overuse of aloe latex can increase the risk of adverse effects from cardiac glycoside drugs, such as digoxin, due to potassium depletion. Overuse of aloe, along with cardiac glycoside drugs, can increase the risk of toxicity.
Anticoagulant/Antiplatelet Drugs
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
In vitro research shows that aloe gel can inhibit platelet aggregation. This inhibition was greater than that seen with celecoxib, but less than that seen with aspirin.
Antidiabetes Drugs
Aloe might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Preliminary clinical research suggests aloe gel might lower blood glucose levels and have additive effects when used with antidiabetes drugs. Monitor blood glucose levels closely.
Diuretic Drugs
Theoretically, aloe latex might increase the risk of hypokalemia when taken with diuretic drugs.
Overuse of aloe latex might compound diuretic-induced potassium loss, increasing the risk of hypokalemia.
Stimulant Laxatives
Theoretically, aloe latex might increase the risk for fluid and electrolyte loss when taken with stimulant laxatives.
Due to cathartic laxative effects of aloe latex, concomitant use with other stimulant laxatives might compound fluid and electrolyte loss.
Warfarin (Coumadin)
Theoretically, aloe latex might increase the risk of bleeding when taken with warfarin.
Aloe latex has stimulant laxative effects. In some people aloe latex can cause diarrhea. Diarrhea can increase the effects of warfarin, increase international normalized ratio (INR), and increase the risk of bleeding. Advise patients who take warfarin not to take excessive amounts of aloe vera.
Cytochrome P450 1A2 (Cyp1A2) Substrates
Theoretically, aloe might decrease the levels and clinical effects of CYP1A2 substrates.
In vitro research shows that aloe extract induces CYP1A2 enzymes.
Lactobacillus acidophilus
Antibiotic Drugs
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L. acidophilus.
L. acidophilus preparations usually contain live and active organisms. Therefore, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and L. acidophilus preparations by at least two hours.
Apple Pectin, Powder
Digoxin (Lanoxin)
Theoretically, pectin might reduce the absorption of digoxin, potentially decreasing its effectiveness.
A small clinical study shows that taking digoxin with a kaolin-pectin suspension reduces the absorption of digoxin by about 62%. It is unclear if these effects are due to pectin, kaolin, or the combination.
Lovastatin (Mevacor)
Theoretically, pectin might reduce the absorption of lovastatin, potentially decreasing its effectiveness.
Case reports suggest that concomitant use of pectin and lovastatin might reduce the cholesterol-lowering effect of lovastatin, possibly due to reduced intestinal absorption of lovastatin.
Tetracycline Antibiotics
Theoretically, pectin might reduce the absorption of tetracycline antibiotics, potentially decreasing their effectiveness.
A small clinical study shows that taking tetracycline with bismuth subsalicylate in a kaolin-pectin suspension reduces the absorption of tetracycline by about 34%. It is unclear if these effects are due to pectin, kaolin, bismuth subsalicylate, or the combination.
Brand information
Manufacturer and brand details for Colon Pro Health, from the product label.
Logos Nutritionals
See all Logos Nutritionals products- Name
- Logos Nutritionals, LLC.
- Street Address
- 912 Killian Hill Road SW, Ste. 202-O
- City
- Lilburn
- State
- GA
- ZipCode
- 30047
- Phone Number
- 800-556-5530
- Web Address
- www.logosnutritionals.com
Colon Pro Health by Logos Nutritionals: Common Questions
Does Colon Pro Health by Logos Nutritionals interact with any medications?
How can one product interact with so many drugs?
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Is glucomannan safe to take?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Colon Pro Health’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Lactobacillus Acidophilus
Interacts with 182 drugsLactobacillus acidophilus is a 'friendly' bacterium used as a probiotic to support gut and vaginal health. It is generally well tolerated in healthy people, and there is reasonable evidence...
Read the full Lactobacillus Acidophilus monograph → Herb & supplement monographPectin
Interacts with 23 drugsPectin is a natural soluble fiber found in fruits like apples and citrus, and it is widely used in foods and as a fiber supplement. It may modestly help with cholesterol, blood sugar, and di...
Read the full Pectin monograph → Herb & supplement monographAloe
Interacts with 461 drugsAloe vera gel is widely used on the skin for minor burns and irritation, and some research suggests it may help. Aloe latex (the yellow part) is a strong laxative that can cause cramping and...
Read the full Aloe monograph → Herb & supplement monographBlack Walnut
Black walnut is a tree whose green hulls are traditionally used as a natural antiparasitic and digestive remedy, but solid human evidence for these uses is lacking. It contains a compound ca...
Read the full Black Walnut monograph → Herb & supplement monographGlucomannan
Interacts with 2,022 drugsGlucomannan is a soluble fiber from the konjac root that swells into a gel in your stomach, which may help with mild weight loss, constipation, and modestly lowering cholesterol. It is gener...
Read the full Glucomannan monograph →Sources & How We Checked
Colon Pro Health's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 85 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Lactobacillus Acidophilus 15 references
- Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
- Begtrup LM, de Muckadell OB, Kjeldsen J, Christensen RD, Jarbøl DE. Long-term treatment with probiotics in primary care patients with irritable bowel syndrome--a randomised, double-blind, placebo controlled trial. Scand J Gastroenterol 2013;48(10):1127-35 PubMed
- Chatterjee S, Kar P, Das T, Ray S, Gangulyt S, Rajendiran C, Mitra M. Randomised placebo-controlled double blind multicentric trial on efficacy and safety of Lactobacillus acidophilus LA-5 and Bifidobacterium BB-12 for prevention of antibiotic-associated
- Shavakhi A, Tabesh E, Yaghoutkar A, Hashemi H, Tabesh F, Khodadoostan M,Minakari M, Shavakhi S, Gholamrezaei A. The effects of multistrain probiotic compound on bismuth-containing quadruple therapy for Helicobacter pylori infection: a randomized placebo-c
- Karamali M, Dadkhah F, Sadrkhanlou M, et al. Effects of probiotic supplementation on glycaemic control and lipid profiles in gestational diabetes: a randomized, double-blind, placebo-controlled trial. Diabetes Metab 2016;42(4):234-41. PubMed
- Badehnoosh B, Karamali M, Zarrati M, et al. The effects of probiotic supplementation on biomarkers of inflammation, oxidative stress and pregnancy outcomes in gestational diabetes. J Matern Fetal Neonatal Med. 2018 May;31(9):1128-1136.
- Kumar S, Kumar R, Rohilla L, Jacob N, Yadav J, Sachdeva N. A high potency multi-strain probiotic improves glycemic control in children with new-onset type 1 diabetes mellitus: A randomized, double-blind, and placebo-controlled pilot study. Pediatr Diabete
- Shahriari A, Karimi E, Shahriari M, Aslani N, Khooshideh M, Arab A. The effect of probiotic supplementation on the risk of gestational diabetes mellitus among high-risk pregnant women: A parallel double-blind, randomized, placebo-controlled clinical trial PubMed
- Xiao SD, Zhang DZ, Lu H, et al. Multicenter, randomized, controlled trial of heat-killed Lactobacillus acidophilus LB in patients with chronic diarrhea. Adv Ther. 2003;20(5):253-60.
- Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed
- Ozer M, Goksu SY, Shahverdiani A, Mustafa M. Lactobacillus acidophilus-induced endocarditis and associated splenic abscess. Case Rep Infect Dis 2020;2020:1382709.
- Sadrin S, Sennoune S, Gout B, et al. A 2-strain mixture of Lactobacillus acidophilus in the treatment of irritable bowel syndrome: A placebo-controlled randomized clinical trial. Dig Liver Dis 2020;52(5):534-540. PubMed
- Stoffer JN, Slingsby TJ, Giuliari GP. Lactobacillus acidophilus endophthalmitis after intravitreal bevacizumab injection requiring intraocular lens explantation. Can J Ophthalmol 2022;57(1):e21-e22. PubMed
- Cukovic-Cavka S, Likic R, Francetic I, Rustemovic N, Opacic M, Vucelic B. Lactobacillus acidophilus as a cause of liver abscess in a NOD2/CARD15-positive patient with Crohn's disease. Digestion 2006;73(2-3):107-10.
- Hui J, Ren Y, Wang Y, Han Q. Lactobacillus acidophilus endophthalmitis postcataract operation: A case report with a literature review. Ocul Immunol Inflamm 2023.
See these in context on the Lactobacillus Acidophilus monograph →
Pectin 11 references
- Jaakkola MS, et al. Asthma caused by occupational exposure to pectin. J Allergy Clin Immunol 1997;100:575-6. PubMed
- Westphal W, et al. [Exogenous allergic asthma following pectin exposure-a new occupational allergen]. Pneumologie 1990;44(Suppl 1):337-8.
- Baldwin JL, et al. Pectin-induced occupational asthma. Chest 1993;104:1936-7. PubMed
- Cohen AJ, Forse MS, Tarlo SM. Occupational asthma caused by pectin inhalation during the manufacture of jam. Chest 1993;103:309-11.
- Kraut A, et al. Christmas candy maker's asthma. IgG4-mediated pectin allergy. Chest 1992;102:1605-7. PubMed
- Richter WO, Jacob BG, Schwandt P. Interaction between fibre and lovastatin. Lancet 1991;338:706.
- Albert KS, Ayres JW, DiSanto AR, et al. Influence of kaolin-pectin suspension on digoxin bioavailability. J Pharm Sci 1978;67:1582-6. PubMed
- Albert KS, Welch RD, DeSante KA, et al. Decreased tetracycline bioavailability caused by a bismuth subsalicylate antidiarrheal mixture. J Pharm Sci 1979;68:586-8. PubMed
- Electronic Code of Federal Regulations. Title 21. Part 182 -- Substances Generally Recognized As Safe. Available at: https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?CFRPart=182
- Federal Register April 17,2003. Anti-Diarrheal Products for over-the-counter human use; final monograph. Available at: http://www.fda.gov/OHRMS/DOCKETS/98fr/03-9380.pdf (Accessed 27 December 2004).
- Washio K, Nakamura M, Sato N, et al. Anaphylaxis in a pectin- and cashew nut-allergic child caused by a citrus bath. Allergol Int 2022;71(1):155-157. PubMed
Aloe 41 references
- Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
- Wichtl MW. Herbal Drugs and Phytopharmaceuticals. Ed. N.M. Bisset. Stuttgart: Medpharm GmbH Scientific Publishers, 1994.
- Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
- Nusko G, Schneider B, Schneider I, et al. Anthranoid laxative use is not a risk factor for colorectal neoplasia: results of a prospective case control study. Gut 2000;46:651-5. PubMed
- Luyckx VA, Ballantine R, Claeys M, et al. Herbal remedy-associated acute renal failure secondary to Cape aloes. Am J Kidney Dis 2002;39:E13. PubMed
- Rajasekaran S, Sivagnanam K, Ravi K, Subramanian S. Hypoglycemic effect of Aloe vera gel on streptozotocin-induced diabetes in experimental rats. J Med Food 2004;7:61-6.
- Williams MS, Burk M, Loprinzi CL, et al. Phase III double-blind evaluation of an aloe vera gel as a prophylactic agent for radiation-induced skin toxicity. Int J Radiat Oncol Biol Phys 1996;36:345-9. PubMed
- Vogler BK, Ernst E. Aloe vera: a systematic review of its clinical effectiveness. Br J Gen Pract 1999;49:823-8.
- Bottenberg MM, Wall GC, Harvey RL, Habib S. Oral aloe vera-induced hepatitis. Ann Pharmacother 2007;41:1740-3. PubMed
- Rabe C, Musch A, Schirmacher P, et al. Acute hepatitis induced by an Aloe vera preparation: a case report. World J Gastroenterol 2005;11:303-4. PubMed
- Kanat O, Ozet A, Ataergin S. Aloe vera-induced acute toxic hepatitis in a healthy young man. Eur J Int Med 2006;17:589. PubMed
- Mueller SO, Stopper H. Characterization of the genotoxicity of anthraquinones in mammalian cells. Biochim Biophys Acta 1999;1428:406-14. PubMed
- Schorkhuber M, Richter M, Dutter A, et al. Effect of anthraquinone laxatives on the proliferation and urokinase secretion of normal, premalignant and malignant colonic epithelial cells. Eur J Cancer 1998;34:1091-8. PubMed
- Yang HN, Kim DJ, Kim YM, et al. Aloe-induced toxic hepatitis. J Korean Med Sci 2010;25:492-5. PubMed
- Choonhakarn C, Busaracome P, Sripanidkulchai B, et al. A prospective, randomized clinical trial comparing topical aloe vera with 0.1% triamcinolone acetonide in mild to moderate plaque psoriasis. J.Eur.Acad.Dermatol.Venereol. 2010;24:168-72. PubMed
- Ishii Y, Tanizawa H, Takino Y. Studies of aloe. IV. Mechanism of cathartic effect. (3). Biol Pharm Bull. 1994;17:495-7. PubMed
- Ishii Y, Tanizawa H, Takino Y. Studies of aloe. V. Mechanism of cathartic effect. (4). Biol Pharm Bull. 1994;17:651-3. PubMed
- Nelemans FA. Clinical and toxicological aspects of anthraquinone laxatives. Pharmacology. 1976;14 Suppl 1:73-7. PubMed
- Paulsen E, Korsholm L, Brandrup F. A double-blind, placebo-controlled study of a commercial Aloe vera gel in the treatment of slight to moderate psoriasis vulgaris. J Eur Acad Dermatol Venereol. 2005;19:326-31.
- Huseini HF, Kianbakht S, Hajiaghaee R, et al. Anti-hyperglycemic and anti-hypercholesterolemic effects of Aloe vera leaf gel in hyperlipidemic type 2 diabetic patients: a randomized double-blind placebo-controlled clinical trial. Planta Med. 2012;78:311-6
- Ferreira, M., Teixeira, M., Silva, E., and Selores, M. Allergic contact dermatitis to Aloe vera. Contact Dermatitis 2007;57(4):278-279.
- Choonhakarn, C., Busaracome, P., Sripanidkulchai, B., and Sarakarn, P. The efficacy of aloe vera gel in the treatment of oral lichen planus: a randomized controlled trial. Br J Dermatol 2008;158(3):573-577. PubMed
- Baretta, Z., Ghiotto, C., Marino, D., and Jirillo, A. Aloe-induced hypokalemia in a patient with breast cancer during chemotherapy. Ann.Oncol. 2009;20(8):1445-1446. PubMed
- Hunter, D. and Frumkin, A. Adverse reactions to vitamin E and aloe vera preparations after dermabrasion and chemical peel. Cutis 1991;47(3):193-196.
- Alvarez-Perea, A., Garcia, A. P., Hernandez, A. L., de, Barrio M., and Baeza, M. L. Urticaria due to aloe vera: a new sensitizer? Ann.Allergy Asthma Immunol. 2010;105(5):404-405. PubMed
- Hogan, D. J. Widespread dermatitis after topical treatment of chronic leg ulcers and stasis dermatitis. CMAJ. 2-15-1988;138(4):336-338.
- Savchak VI. Acute bullous allergic dermatitis due to local application of aloe leaves. Vestnik Dermatologii i Venerologii 1977;12:44-45.
- Nakamura, T. and Kotajima, S. Contact dermatitis from aloe arborescens. Contact Dermatitis 1984;11(1):51. PubMed
- Shoji, A. Contact dermatitis to Aloe arborescens. Contact Dermatitis 1982;8(3):164-167. PubMed
- Morrow, D. M., Rapaport, M. J., and Strick, R. A. Hypersensitivity to aloe. Arch Dermatol. 1980;116(9):1064-1065. DOI
- Cosmetic Ingredient Review Expert Panel. Final report on the safety assessment of AloeAndongensis Extract, Aloe Andongensis Leaf Juice,aloe Arborescens Leaf Extract, Aloe Arborescens Leaf Juice, Aloe Arborescens Leaf Protoplasts, Aloe Barbadensis Flower E
- Bhalang K, Thunyakitpisal P, Rungsirisatean N. Acemannan, a polysaccharide extracted from Aloe vera, is effective in the treatment of oral aphthous ulceration. J Altern Complement Med 2013;19(5):429-34.
- Hajheydari Z, Saeedi M, Morteza-Semnani K, Soltani A. Effect of Aloe vera topical gel combined with tretinoin in treatment of mild and moderate acne vulgaris: a randomized, double-blind, prospective trial. J Dermatolog Treat 2014;25(2):123-9.
- Jiménez-Encarnación E, Ríos G, Muñoz-Mirabal A, Vilá LM. Euforia-induced acute hepatitis in a patient with scleroderma. BMJ Case Rep 2012;2012. PubMed
- Lee J, Lee MS, Nam KW. Acute toxic hepatitis caused by an aloe vera preparation in a young patient: a case report with a literature review. Korean J Gastroenterol 2014;64(1):54-8. PubMed
- Guo X, Mei N. Aloe Vera - A Review of Toxicity and Adverse Clinical Effects. J Environ Sci Health C Environ Carcinog Ecotoxicol Rev 2016;34(2):77-96.
- Hoogenboom TCH, Patel N, Cook NA, Williams R, Taylor-Robinson SD, Lim AKP. The effect of Aloe vera juice on liver enzymes and hepatic structure in a healthy population. Integr Med (Encinitas) 2020;19(3):30-4.
- Mushtaq S, Mushtaq Z, Sarfraz J, et al. Comparison of effect of aloe vera gel with aspirin and celecoxib on platelet aggregation. Professional Med J. 2020; 27(5):973-978. DOI
- Haron MH, Dale O, Martin K, et al. Evaluation of the Herb-Drug Interaction Potential of Commonly Used Botanicals on the US Market with Regard to PXR- and AhR-Mediated Influences on CYP3A4 and CYP1A2. J Diet Suppl 2022. PubMed
- Sabbaghzadegan S, Soltani MH, Kamalinejad M, Bahrami M, Kabir A, Dadmehr M. The effect of a standardized capsule of Aloe vera gel on the quality of life in patients with systolic heart failure: A randomized double-blind placebo-controlled clinical trial.
- Lewis ED, Crowley DC, Guthrie N, Evans M. Healthy adults supplemented with a nutraceutical formulation containing Aloe vera gel, rosemary and Poria cocos enhances the effect of influenza vaccination in a randomized, triple-blind, placebo-controlled trial. PubMed
Black Walnut 3 references
- Blumenthal M, ed. The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Trans. S. Klein. Boston, MA: American Botanical Council, 1998.
- McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
- Food and Drug Administration. Food Allergen Labeling and Consumer Protection Act of 2004 (FALCPA); Public Law 108-282, Title II. Accessed on May 19, 2021. Available at: https://www.fda.gov/food/food-allergensgluten-free-guidance-documents-regulatory-infor
Glucomannan 15 references
- Henry DA, Mitchell AS, Aylward J, et al. Glucomannan and risk of oesophageal obstruction. Br Med J 1986;292:591-2. PubMed
- Shima K, Tanaka A, Ikegami H, et al. Effect of dietary fiber, glucomannan, on absorption of sulfonylurea in man. Horm Metab Res 1983;15:1-3. PubMed
- Villaverde, A. F., Benlloch, S., Berenguer, M., Miguel, Rayon J., Pina, R., and Berenguer, J. Acute hepatitis of cholestatic type possibly associated with the use of glucomannan (amorphophalus konjac). J Hepatol. 2004;41(6):1061-1062. PubMed
- Yoshida, M., Vanstone, C. A., Parsons, W. D., Zawistowski, J., and Jones, P. J. Effect of plant sterols and glucomannan on lipids in individuals with and without type II diabetes. Eur.J Clin Nutr. 2006;60(4):529-537. PubMed
- Wood, R. J., Fernandez, M. L., Sharman, M. J., Silvestre, R., Greene, C. M., Zern, T. L., Shrestha, S., Judelson, D. A., Gomez, A. L., Kraemer, W. J., and Volek, J. S. Effects of a carbohydrate-restricted diet with and without supplemental soluble fiber
- Vanderbeek, P. B., Fasano, C., O'Malley, G., and Hornstein, J. Esophageal obstruction from a hygroscopic pharmacobezoar containing glucomannan. Clin Toxicol.(Phila) 2007;45(1):80-82. PubMed
- Bernstein, J. A., Crandall, M. S., and Floyd, R. Respiratory sensitization of a food manufacturing worker to konjac glucomannan. J Asthma 2007;44(8):675-680. PubMed
- Shichijo, K., Kobayashi, Y., Fueki, R., Shimoyama, K., and Masaya, M. [2 cases of konjac bronchial asthma found outside the "konnyaku" producing district]. Arerugi 1969;18(2):97-100.
- Carabin IG, Lyon MR, Wood S, et al. Supplementation of the diet with the functional fiber PolyGlycoplex is well tolerated by healthy subjects in a clinical trial. Nutr J 2009;8:9. PubMed
- Lyon MR, Reichert RG. The effect of a novel viscous polysaccharide along with lifestyle changes on short-term weight loss and associated risk factors in overweight and obese adults: an observational retrospective clinical program analysis. Altern Med Rev
- Lyon M, Wood S, Pelletier X, et al. Effects of a 3-month supplementation with a novel soluble highly viscous polysaccharide on anthropometry and blood lipids in nondieting overweight or obese adults. J Hum Nutr Diet 2011;24(4):351-9. PubMed
- Han Y, Zhang L, Liu XQ, Zhao ZJ, Lv LX. Effect of glucomannan on functional constipation in children: a systematic review and meta-analysis of randomised controlled trials. Asia Pac J Clin Nutr 2017;26(3):471-7.
- Health Canada Safety Alert. Health Canada Advises Canadians that natural health products containing glucomannan may cause serious choking if used with insufficient fluid. January 29, 2010. Alert # RA-110003825. https://healthycanadians.gc.ca/recall-alert-
- Mortensen A, Aguilar F, Crebelli, et al. EFSA Panel on Food Additives and Nutrient Sources added to Food. Re-evaluation of konjac gum (E 425 i) and konjac glucomannan (E425 ii) as food additives. EFSA Journal 2017;15(6):4864.
- Zhang Y, Aldamarany WAS, Song G, et al. Influence of konjac glucomannan and its derivatives on the oral pharmacokinetics of antimicrobial agent in antibiotics cocktails: Keep vigilant on dietary fiber supplement. Int J Biol Macromol 2023;251:126306. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC