Interactions on record — worth a quick check against your medications. Based on 5 of 16 ingredients. Check your meds →
Dietary supplement

Complete Digestive Blend Ingredients & Drug Interactions

by OL Olympian Labs, Inc. The Optimal Blend

Complete Digestive Blend label
See full label image
Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Complete Digestive Blend against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Complete Digestive Blend is a dietary supplement by OL Olympian Labs, Inc. The Optimal Blend with 16 active ingredients. Its ingredients are commonly taken for lactose intolerance, gas and bloating after dairy, diarrhea from dairy foods.Based on those ingredients, 122 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Serrapeptase. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Complete Digestive Blend by OL Olympian Labs, Inc. The Optimal Blend

Ask about any prescription or over-the-counter medication and we check it for interactions with Complete Digestive Blend by OL Olympian Labs, Inc. The Optimal Blend — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Complete Digestive Blend by OL Olympian Labs, Inc. The Optimal Blend

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 6 of its 16 active ingredients.
  • “Amylase” is listed as a grouped ingredient — the label doesn't break down how much of each component you get.
  • “HemiSeb(R)” is listed as a grouped ingredient — the label gives one combined amount (366 HCU) without saying how much of each component you get.

Complete Digestive Blend contains 16 active ingredients — a blend of digestive enzymes designed to break down different components of food. Lactase helps you digest lactose (the sugar in milk).

Serrapeptase is a proteolytic enzyme that breaks down proteins and has been studied for other uses. The rest are plant-derived and fungal enzymes: proteases break down proteins, lipase breaks down fats, and the others target carbohydrates, fiber, and other plant compounds.

The inactive ingredients are the capsule itself, rice flour, microcrystalline cellulose (a binder), silicon dioxide, and ascorbyl palmitate (a preservative).

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: full spectrum enzyme blend and digestive aid.
  • We looked for evidence on: Dyspepsia, Lactose intolerance, Postoperative swelling, bloating and gas, fat digestion, indigestion.
  • The strongest evidence on file: Lactase is rated "Effective" for Lactose intolerance (Natural Medicines).
  • Also on file: Lipase is rated "Insufficient Reliable Evidence To Rate" for Dyspepsia.
  • Also on file: Serrapeptase is rated "Insufficient Reliable Evidence To Rate" for Postoperative swelling.

The evidence backing these ingredients is mixed. Lactase is effective for lactose intolerance — if you can't digest milk sugar, it helps.

For serrapeptase, the data we hold shows insufficient evidence for its claimed uses, which include chronic bronchitis, asthma, atherosclerosis, back pain, and osteoporosis. The same is true for protease, lipase, and phytase — the evidence for their use as supplements isn't established in our data.

Most of these are digestive enzymes found naturally in your gut, but whether adding them as supplements works is a question your pharmacist can help you think through based on what you're looking for.

The evidence, ingredient by ingredient Lactase Proteolytic Enzymes (proteases) Lipase Serrapeptase Phytase

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 5 of the 5 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 5 of 5.
  • General safety write-ups exist for 5 of 5.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Lactase is generally well tolerated and likely safe in pregnancy and while breastfeeding. Serrapeptase is tolerated short-term but has limited long-term safety data, and should be avoided in pregnancy and while breastfeeding due to insufficient data.

Protease may cause digestive upset or allergic reactions and is best avoided in pregnancy and during breastfeeding. Lipase is generally well tolerated, though people with serious digestive conditions should use it only under medical guidance, and safety data in pregnancy and breastfeeding are limited.

Phytase has very limited human safety data and should be avoided unless your doctor advises otherwise; safety in pregnancy and breastfeeding is unknown. Occupational exposure to powdered forms of lactase and phytase has caused allergic reactions in workers; you're taking this orally, but if you're sensitive to enzymes, mention that to your pharmacist.

Side effects, ingredient by ingredient Lactase Proteolytic Enzymes (proteases) Lipase Serrapeptase Phytase

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 5 matched ingredients can interact with medications — Serrapeptase.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 122 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take blood thinners or antiplatelet drugs (warfarin, clopidogrel, aspirin, etc.), check this product with your pharmacist — serrapeptase poses a moderate interaction risk. No other medication interactions are documented for the other ingredients we could check.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with clinical evidence supporting its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This blend is a digestive enzyme supplement, most useful if you have lactose intolerance or want to try enzyme support for digestion. If you take blood thinners or antiplatelet medications, check with your pharmacist before starting — serrapeptase may increase bleeding risk.

Pregnant or breastfeeding? Talk to your doctor first, especially about serrapeptase and phytase.

Your pharmacist can help you decide if it's right for your situation.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 5 of 16 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Mar 25, 2015.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Complete Digestive Blend, straight from the product label.

Brand OL Olympian Labs, Inc. The Optimal Blend
Barcode (UPC) 710013001177
Net contents 60 Capsule(s)
Market status On market
Date entered into DSLD Mar 25, 2015
DSLD ID 43308
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult Female (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Complete Digestive Blend by OL Olympian Labs, Inc. The Optimal Blend, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
30
UPC/BARCODE
710013001177
IngredientAmount% DV
Lactase1270 LACU--
Cellulase251 CU--
Glucoamylase15 AG--
Xylanase0 NP--
Pectinase0 NP--
Beta-Glucanase0 NP--
Phytase0 NP--
Hemicellulase0 NP--
Diastase22100 DP--
Alpha-Amylase0 NP--
Beta-Amylase0 NP--
Amylase0 NP--
Protease0 NP--
Lipase0 NP--
Sucrase290 INVU--
Peptizyme SP(R)1000 SPU--
Serrapeptase0 NP--
HemiSeb(R)366 HCU--

Other ingredients: Vegetarian Capsule, Rice Flour, Microcrystalline Cellulose, Silicon Dioxide, Ascorbyl Palmitate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested Use: As a dietary supplement, take two (2) capsules daily or as directed by a healthcare professional.

Precautions

Caution: If you are pregnant, nursing or have a medical condition, or are taking medication, consult your healthcare professional before taking this or any other nutritional supplement.

Discontinue use if allergic reaction occurs.

KEEP OUT OF REACH OF CHILDREN.

General Statements

The Complete Digestive Blend is a full spectrum enzyme blend and digestive aid. Contains enzymes that breakdown starches, fat, proteins, sugars, cellulose and lactose to improve digestion.

Stimulates recovery from injury of both muscle and skin. Also digests unwanted debris in the blood such as viruses and bacteria and supports the immune system.*

- Reduces Bloating - Improves Absorption of Nutrients and Digestion - Supports the Immune System

Made in USA

Storage

STORE IN A COOL, DRY PLACE.

FDA Disclaimer Statement

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Seals/Symbols

OL OLYMPIAN LABS, INC(TM)

Brand IP Statement(s)

THE OPTIMAL BLEND FOR DYNAMIC WOMEN(TM)

FDA Statement of Identity

DIETARY SUPPLEMENT

General

REV 09/20/13

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Complete Digestive Blend by OL Olympian Labs, Inc. The Optimal Blend label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Complete Digestive Blend label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Complete Digestive Blend by OL Olympian Labs, Inc. The Optimal Blend

These are the 16 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Lactase

No known
interactions
1270 LACU per serving

Lactase is a digestive enzyme supplement that helps people who lack enough natural lactase break down lactose, the sugar in milk and dairy. It can red...

Lactase monograph & interactions

Cellulase

251 CU per serving

Glucoamylase

15 AG per serving

Diastase

22100 DP per serving

Amylase

0 NP per serving Form: Alpha-Amylase, Beta-Amylase
  • › Alpha-Amylase
  • › Beta-Amylase

Protease

No known
interactions
0 NP per serving Form: Protease I, Protease II, Protease III, Protease IV

Proteolytic enzymes are proteins that help break down other proteins, and common examples include bromelain (from pineapple), papain (from papaya), tr...

Protease monograph & interactions

Lipase

No known
interactions
0 NP per serving Form: Lipase I, Lipase II

Lipase is a digestive enzyme that helps your body break down dietary fats. It is well established as part of prescription pancreatic enzyme therapy fo...

Lipase monograph & interactions

Sucrase

290 INVU per serving Form: Invertase

Peptizyme SP(R)

1000 SPU per serving

Serrapeptase

Interacts with
122 drugs
0 NP per serving Form: Peptizyme SP-EN(R)

Serrapeptase is an enzyme marketed to reduce inflammation, swelling, pain, and mucus, but the human evidence is limited and mostly low quality. If you...

Serrapeptase monograph & interactions

HemiSeb(R)

366 HCU per serving
  • › Xylanase
  • › Pectinase
  • › Beta-Glucanase
  • › Phytase
  • › Hemicellulase

Other (inactive) ingredients: Vegetarian Capsule, Rice Flour, Microcrystalline Cellulose, Silicon Dioxide, Ascorbyl Palmitate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Complete Digestive Blend by OL Olympian Labs, Inc. The Optimal Blend Drug Interactions

Want to check YOUR meds against Complete Digestive Blend?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
122Drugs
122 Moderate

Ingredients driving the most interactions

Serrapeptase 122

Individual Drug Interactions

The ingredients in Complete Digestive Blend interact with 122 drugs. Click any drug to see the details.

1 of the 16 ingredients in Complete Digestive Blend interact with drugs. Each result below shows which ingredient is responsible. Serrapeptase

Each ingredient & the kinds of drugs it affects

For each ingredient in Complete Digestive Blend with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Serrapeptase1 drug type · 122 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, taking serrapeptase with drugs that have antiplatelet or anticoagulant effects might increase the risk of bruising and bleeding.
In vitro research shows that serrapeptase has fibrinolytic activity.

Likelihood Possible Evidence D
Serrapeptase full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Complete Digestive Blend, from the product label.

OL Olympian Labs, Inc. The Optimal Blend

See all OL Olympian Labs, Inc. The Optimal Blend products
Name
Olympian Labs, Inc.
City
Phoenix
State
AZ
ZipCode
85027
Phone Number
1.800.473.5883
Web Address
www.olympianlabs.com
Pharmacist Counseling Corner

Complete Digestive Blend by OL Olympian Labs, Inc. The Optimal Blend: Common Questions

Does Complete Digestive Blend by OL Olympian Labs, Inc. The Optimal Blend interact with any medications?
Yes. Based on its ingredients, Complete Digestive Blend has a known interaction with 122 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Complete Digestive Blend contains 16 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does this help with lactose intolerance?
Lactase, one of the active ingredients, is effective for lactose intolerance. If dairy upsets your stomach because you can't digest the milk sugar, lactase can help. The other enzymes in the blend are meant to support overall digestion, but lactase is the one with proven effectiveness for this.
Can I take it if I'm pregnant?
Not all ingredients have been studied in pregnancy. Lactase is likely safe, but serrapeptase and phytase should be avoided unless your doctor says otherwise. For the other enzymes, there isn't enough data to say one way or the other. Talk with your doctor or pharmacist before starting — they can advise you based on your specific situation.
Can I take it while breastfeeding?
Lactase is likely safe while breastfeeding. Serrapeptase and phytase should be avoided due to lack of safety data. For the other ingredients, we don't have enough information. Check with your doctor or pharmacist first to be sure.
What are the side effects?
Most people tolerate these enzymes well. Serrapeptase may cause epigastric pain (discomfort just below the ribs), gastrointestinal upset, or nausea, though these side effects appeared at the same rate as placebo in studies. Protease may cause digestive upset or allergic reactions. Rare serious allergic reactions have been reported with occupational exposure to enzyme powders, but that's different from taking a supplement by mouth.
Does it actually work for digestion?
The evidence isn't established in our data for most of these enzymes as supplements — we don't have reliable evidence that adding them improves digestion in people without an enzyme deficiency. Lactase is the exception: it's effective for lactose intolerance. If you have specific digestive concerns, your pharmacist can help you figure out whether this blend makes sense for you.
Is this safe if I have digestive problems like IBS or ulcers?
People with serious digestive conditions should use lipase only under medical guidance. For the others, there isn't enough data to say. If you have a digestive disorder, talk with your doctor or pharmacist before taking this — they can make sure it won't interfere with your condition or your medications.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Complete Digestive Blend is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Complete Digestive Blend label
Go deeper

The Full Monographs Behind Complete Digestive Blend’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Lactase

Lactase is a digestive enzyme supplement that helps people who lack enough natural lactase break down lactose, the sugar in milk and dairy. It can reduce gas, bloating, cramping, and diarrhe...

Read the full Lactase monograph → Herb & supplement monograph

Proteolytic Enzymes (proteases)

Proteolytic enzymes are proteins that help break down other proteins, and common examples include bromelain (from pineapple), papain (from papaya), trypsin, chymotrypsin, and pancreatin. Peo...

Read the full Proteolytic Enzymes (proteases) monograph → Herb & supplement monograph

Lipase

Lipase is a digestive enzyme that helps your body break down dietary fats. It is well established as part of prescription pancreatic enzyme therapy for people who cannot make enough of their...

Read the full Lipase monograph → Herb & supplement monograph

Serrapeptase

Interacts with 122 drugs

Serrapeptase is an enzyme marketed to reduce inflammation, swelling, pain, and mucus, but the human evidence is limited and mostly low quality. If you want to try it, choose an enteric-coate...

Read the full Serrapeptase monograph → Herb & supplement monograph

Phytase

Phytase is an enzyme that breaks down phytic acid (phytate) found in grains, beans, nuts, and seeds, which can free up minerals like iron, zinc, and calcium for absorption. It is widely used...

Read the full Phytase monograph →
Sources

Sources & How We Checked

Complete Digestive Blend's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 14 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Lactase 1 reference
  1. Laukkanen A, Ruoppi P, Remes S, Koistinen T, Mäkinen-Kiljunen S. Lactase-induced occupational protein contact dermatitis and allergic rhinoconjunctivitis. Contact Dermatitis. 2007;57(2):89-93. PubMed

See these in context on the Lactase monograph →

Phytase 7 references
  1. Lei XG, Weaver JD, Mullaney E, Ullah AH, Azain MJ. Phytase, a new life for an "old" enzyme. Annu Rev Anim Biosci. 2013;1:283-309. PubMed
  2. Smuts CM, Matsungo TM, Malan L, et al. Effect of small-quantity lipid-based nutrient supplements on growth, psychomotor development, iron status, and morbidity among 6- to 12-mo-old infants in South Africa: a randomized controlled trial. Am J Clin Nutr. 2 PubMed
  3. van Heemst RC, Sander I, Rooyackers J, et al. Hypersensitivity pneumonitis caused by occupational exposure to phytase. Eur Respir J. 2009;33(6):1507-9. PubMed
  4. Baur X, Melching-Kollmuss S, Koops F, Strassburger K, Zober A. IgE-mediated allergy to phytase -- a new animal feed additive. Allergy. 2002;57(10):943-5. PubMed
  5. Doekes G, Kamminga N, Helwegen L, Heederik D. Occupational IgE sensitisation to phytase, a phosphatase derived from Aspergillus niger. Occup Environ Med. 1999;56(7):454-9. PubMed
  6. Brnic M, Hurrell RF, Songré-Ouattara LT, et al. Effect of phytase on zinc absorption from a millet-based porridge fed to young Burkinabe children. Eur J Clin Nutr. 2017;71(1):137-141. PubMed
  7. Koshy JC, Sharabi SE, Feldman EM, Hollier LH Jr, Patrinely JR, Soparkar CN. Effect of dietary zinc and phytase supplementation on botulinum toxin treatments. J Drugs Dermatol. 2012;11(4):507-12.

See these in context on the Phytase monograph →

Proteolytic Enzymes (proteases) 3 references
  1. Weeks JA, Harper RA, Simon RA, Burdick JD. Assessment of sensitization risk of a laundry pre-spotter containing protease. Cutan Ocul Toxicol. 2011;30(4):272-9. PubMed
  2. Marquès LI, Lara S, Abós T, Bartolomé B. Occupational rhinitis due to pepsin. J Investig Allergol Clin Immunol. 2006;16(2):136-7. DOI
  3. Cartier A, Malo JL, Pineau L, Dolovich J. Occupational asthma due to pepsin. J Allergy Clin Immunol. 1984;73(5 Pt 1):574-7. PubMed

See these in context on the Proteolytic Enzymes (proteases) monograph →

Lipase 1 reference
  1. Casper C, Hascoet JM, Ertl T, et al. Recombinant bile salt-stimulated lipase in preterm infant feeding: A randomized phase 3 study. PLoS One. 2016;11(5):e0156071. PubMed

See these in context on the Lipase monograph →

Serrapeptase 2 references
  1. Tachibana M, Mizukoshi O, Harada Y, et al. A multi-centre, double-blind study of serrapeptase versus placebo in post-antrotomy buccal swelling. Pharmatherapeutica 1984;3:526-30..
  2. Mazzone A, Catalani M, Costanzo M, et al. Evaluation of Serratia peptidase in acute or chronic inflammation of otorhinolaryngology pathology: a multicentre, double-blind, randomized trial versus placebo. J Int Med Res 1990;18:379-88.. PubMed

See these in context on the Serrapeptase monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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