CoQ-10 100 mg Ingredients & Drug Interactions
by GNC
What is this page for?
First and foremost: checking CoQ-10 100 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
CoQ-10 100 mg is a dietary supplement by GNC with 1 active ingredient. Its ingredients are commonly taken for heart health, statin-related muscle aches, migraine prevention.Based on those ingredients, 198 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Coenzyme Q-10. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against CoQ-10 100 mg by GNC
Ask about any prescription or over-the-counter medication and we check it for interactions with CoQ-10 100 mg by GNC — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of CoQ-10 100 mg by GNC
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains one active ingredient: coenzyme Q-10, a compound your body makes naturally and that plays a role in energy production in your cells. It's also found in foods like meat and fish.
The softgel also includes inactive ingredients — gelatin, soybean oil, glycerin, chlorophyll, and titanium dioxide — which help form and deliver the capsule.
Does it work?
Strong evidence
The evidence for CoQ-10 varies by what you're taking it for. It's rated likely effective for CoQ-10 deficiency itself.
For fibromyalgia, migraine headaches, congestive heart failure, and diabetic neuropathy, the evidence is rated possibly effective — meaning there's some promising research, but it's not yet conclusive. If you're considering CoQ-10 for a specific condition, talk with your pharmacist or doctor about what the current evidence shows for your particular situation.
How safe is it?
Well-documented data
CoQ-10 is generally well tolerated by most adults when used as directed. In clinical studies, no serious adverse effects were reported.
The most common side effects are gastrointestinal — things like appetite suppression, diarrhea, heartburn, nausea, and vomiting — though these occur in less than 1% of patients. Dividing larger daily doses can help minimize these.
Headache, dizziness, and insomnia have also been reported, along with rare reports of other effects. There is not enough reliable safety data regarding pregnancy, so it's best to avoid CoQ-10 unless your doctor advises otherwise.
Safety while breastfeeding has not been well studied — use caution and check with your doctor before taking this product if you're nursing.
Meds to double-check
Moderate interaction found
Before you start CoQ-10, double-check your medications with your pharmacist, particularly blood thinners like warfarin (Moderate severity), chemotherapy drugs such as alkylating agents (Moderate severity), and any blood pressure medications you're on (Minor severity). If you take any of these, do not start this product without talking to your doctor or pharmacist first.
The bottom line
Scorecard at a glanceFully disclosed formula with clinical evidence supporting its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
CoQ-10 may be worth considering if you have a CoQ-10 deficiency or are interested in its possibly effective uses like migraines or heart health — but you should check with your pharmacist first, especially if you take blood thinners like warfarin, chemotherapy drugs, or blood pressure medications. The interaction with warfarin is the main concern here.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jun 23, 2017.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about CoQ-10 100 mg, straight from the product label.
| Brand | GNC |
|---|---|
| Barcode (UPC) | 048107121198 |
| Net contents | 60 Softgel(s) |
| Market status | On market |
| Date entered into DSLD | Jun 23, 2017 |
| DSLD ID | 75290 |
| Product type | Non-nutrient/non-botanical |
| Supplement form | Softgel Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for CoQ-10 100 mg by GNC, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Coenzyme Q-10 | 100 mg | -- |
Other ingredients: Gelatin, Soybean Oil, Glycerin, Chlorophyll, Titanium Dioxide
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
General Statements
Clinically shown to support heart health Helps replenish CoQ-10 levels reduced by statin drugs
Potency verified by GNC procedure #5012. Conforms to USP <2091> for weight. Meets USP <2040> disintegration.
FDA Statement of Identity
Dietary Supplement
General
CODE 785322 ARG
Suggested/Recommended/Usage/Directions
Directions: As a dietary supplement, take one to four softgel capsules daily after a meal.
Precautions
Warning: Consult your physician prior to using this product if you are pregnant, nursing, taking medication, or have a medical condition.
Discontinue use two weeks prior to surgery.
Keep out of reach of children.
Formulation
No sugar, no starch, no artificial colors, no artificial flavors, no preservatives, no wheat, gluten free, no corn, no dairy, yeast free.
Storage
Store in a cool, dry place.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
CoQ-10 100 mg by GNC label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in CoQ-10 100 mg by GNC
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 Softgel Capsule(s) Dosage formSoftgel Capsule Amounts shown are per serving.
Coenzyme Q-10
Interacts with198 drugs
CoQ10 is a vitamin-like substance your body makes naturally that helps cells produce energy and acts as an antioxidant. It is generally well tolerated...
Coenzyme Q-10 monograph & interactionsOther (inactive) ingredients: Gelatin, Soybean Oil, Glycerin, Chlorophyll, Titanium Dioxide. These complete the product’s ingredient list but are not active constituents.
CoQ-10 100 mg by GNC Drug Interactions
HelloPharmacist Interaction Report
CoQ-10 100 mg by GNC does interact with some medications, most notably blood thinners.
Coenzyme Q-10 is chemically similar to vitamin K and may have procoagulant effects — meaning it could reduce how well warfarin (Coumadin) and similar blood thinners work. There have been four reported cases of decreased warfarin effectiveness linked to CoQ-10.
If you're on warfarin, this one needs a conversation with your pharmacist or doctor before you start.
Read the full breakdown — every affected drug type, severity by severity
CoQ-10 may also reduce the effectiveness of certain chemotherapy drugs, particularly alkylating agents like cyclophosphamide. The concern is that CoQ-10's antioxidant properties might shield tumor cells from the oxidative stress these drugs rely on to work.
If you're undergoing cancer treatment, check with your oncologist first.
Another consideration: CoQ-10 can lower blood pressure, so if you're already taking blood pressure medications, there's a potential for additive effects — meaning your pressure might drop further than intended. This is rated Minor, but it's worth monitoring.
Additionally, there are other common medications out there whose interaction status with CoQ-10 we haven't documented. Use the medication checker on this page to verify your exact prescriptions before you start.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against CoQ-10 100 mg?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in CoQ-10 100 mg interact with 198 drugs. Click any drug to see the details.
1 of the 1 ingredient in CoQ-10 100 mg interact with drugs. Each result below shows which ingredient is responsible. Coenzyme Q-10
FenoldopamCorlopam
How Fenoldopam interacts with CoQ-10 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q-10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q-10 + Fenoldopam interactionFosinoprilMonopril
How Fosinopril interacts with CoQ-10 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q-10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q-10 + Fosinopril interactionFosinopril, HydrochlorothiazideMonopril HCT
How Fosinopril, Hydrochlorothiazide interacts with CoQ-10 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q-10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q-10 + Fosinopril, Hydrochlorothiazide interactionFurosemideLasix
How Furosemide interacts with CoQ-10 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q-10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q-10 + Furosemide interactionGuanabenz AcetateWytensin
How Guanabenz Acetate interacts with CoQ-10 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q-10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q-10 + Guanabenz Acetate interactionGuanadrel SulfateHylorel
How Guanadrel Sulfate interacts with CoQ-10 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q-10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q-10 + Guanadrel Sulfate interactionGuanethidine MonosulfateIsimil, Ismelin
How Guanethidine Monosulfate interacts with CoQ-10 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q-10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q-10 + Guanethidine Monosulfate interactionGuanethidine, HydrochlorothiazideEsimil
How Guanethidine, Hydrochlorothiazide interacts with CoQ-10 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q-10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q-10 + Guanethidine, Hydrochlorothiazide interactionGuanfacineTenex
How Guanfacine interacts with CoQ-10 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q-10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q-10 + Guanfacine interactionHydralazineApresoline, Apresoline Injection, Dralzine, Hydralazine, Hylazin
How Hydralazine interacts with CoQ-10 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q-10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q-10 + Hydralazine interactionHydralazine, HydrochlorothiazideApresazide, Apresoline-Esidrix
How Hydralazine, Hydrochlorothiazide interacts with CoQ-10 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q-10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q-10 + Hydralazine, Hydrochlorothiazide interactionHydralazine, Hydrochlorothiazide, ReserpineSer-Ap-Es, Unipres, Uniserp
How Hydralazine, Hydrochlorothiazide, Reserpine interacts with CoQ-10 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q-10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q-10 + Hydralazine, Hydrochlorothiazide, Reserpine interactionHydralazine, ReserpineSerpasil-Apresoline1, Serpasil-Apresoline2
How Hydralazine, Reserpine interacts with CoQ-10 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q-10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q-10 + Hydralazine, Reserpine interactionHydrochlorothiazideAquazide, Aquazide H, Esidrix, HCTZ, Hydro, Hydro-D +3 more
How Hydrochlorothiazide interacts with CoQ-10 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q-10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q-10 + Hydrochlorothiazide interactionHydrochlorothiazide, IrbesartanAvalide
How Hydrochlorothiazide, Irbesartan interacts with CoQ-10 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q-10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q-10 + Hydrochlorothiazide, Irbesartan interactionHydrochlorothiazide, LabetalolTrandate HCT
How Hydrochlorothiazide, Labetalol interacts with CoQ-10 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q-10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q-10 + Hydrochlorothiazide, Labetalol interactionHydrochlorothiazide, LisinoprilPrinzide, Zestoretic
How Hydrochlorothiazide, Lisinopril interacts with CoQ-10 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q-10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q-10 + Hydrochlorothiazide, Lisinopril interactionHydrochlorothiazide, Losartan PotassiumHyzaar
How Hydrochlorothiazide, Losartan Potassium interacts with CoQ-10 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q-10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q-10 + Hydrochlorothiazide, Losartan Potassium interactionHydrochlorothiazide, MethyldopaAldoril 15, Aldoril 25, Aldoril D30, Methazide
How Hydrochlorothiazide, Methyldopa interacts with CoQ-10 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q-10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q-10 + Hydrochlorothiazide, Methyldopa interactionHydrochlorothiazide, MetoprololLopressor HCT
How Hydrochlorothiazide, Metoprolol interacts with CoQ-10 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q-10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q-10 + Hydrochlorothiazide, Metoprolol interactionHydrochlorothiazide, MoexiprilUniretic
How Hydrochlorothiazide, Moexipril interacts with CoQ-10 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q-10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q-10 + Hydrochlorothiazide, Moexipril interactionHydrochlorothiazide, PindololViskazide
How Hydrochlorothiazide, Pindolol interacts with CoQ-10 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q-10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q-10 + Hydrochlorothiazide, Pindolol interactionHydrochlorothiazide, PropranololInderide
How Hydrochlorothiazide, Propranolol interacts with CoQ-10 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q-10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q-10 + Hydrochlorothiazide, Propranolol interactionHydrochlorothiazide, QuinaprilAccuretic
How Hydrochlorothiazide, Quinapril interacts with CoQ-10 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q-10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q-10 + Hydrochlorothiazide, Quinapril interactionHydrochlorothiazide, ReserpineHydropres, Serpasil-Esidrix, Serpasil-Esidrix #1, Serpasil-Esidrix #2
How Hydrochlorothiazide, Reserpine interacts with CoQ-10 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q-10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q-10 + Hydrochlorothiazide, Reserpine interactionHydrochlorothiazide, SpironolactoneAldactazide, Aldactide 25, Aldactide 50, Spirozine
How Hydrochlorothiazide, Spironolactone interacts with CoQ-10 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q-10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q-10 + Hydrochlorothiazide, Spironolactone interactionHydrochlorothiazide, TimololTimolide
How Hydrochlorothiazide, Timolol interacts with CoQ-10 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q-10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q-10 + Hydrochlorothiazide, Timolol interactionHydrochlorothiazide, TriamtereneDyazide, Maxzide, Maxzide-25, Triamzide, Triazide
How Hydrochlorothiazide, Triamterene interacts with CoQ-10 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q-10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q-10 + Hydrochlorothiazide, Triamterene interactionHydrochlorothiazide, ValsartanDiovan HCT
How Hydrochlorothiazide, Valsartan interacts with CoQ-10 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q-10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q-10 + Hydrochlorothiazide, Valsartan interactionHydroflumethiazideSaluron
How Hydroflumethiazide interacts with CoQ-10 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q-10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q-10 + Hydroflumethiazide interactionEach ingredient & the kinds of drugs it affects
For each ingredient in CoQ-10 100 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Coenzyme Q-10
Alkylating Agents
Coenzyme Q10 has antioxidant effects. Theoretically, this may reduce the activity of chemotherapy drugs that generate free radicals.
Theoretically, antioxidants such as coenzyme Q10 might protect tumor cells from chemotherapeutic agents that work by inducing oxidative stress, such as alkylating agents (e.g., cyclophosphamide) and radiation therapy. The clinical importance of this interaction is unknown.
Warfarin (Coumadin)
Coenzyme Q10 is chemically similar to menaquinone and might have vitamin K-like procoagulant effects, which could decrease the effects of warfarin.
Concomitant use of coenzyme Q10 and warfarin might reduce the anticoagulant effects of warfarin. Four cases of decreased warfarin efficacy thought to be due to coenzyme Q10 have been reported. However, there is some preliminary clinical research that suggests coenzyme Q10 might not significantly decrease the effects of warfarin in patients who have a stable INR.
Antihypertensive Drugs
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Some clinical research shows that coenzyme Q10 can significantly lower blood pressure, although other studies have shown conflicting results.
Brand information
Manufacturer and brand details for CoQ-10 100 mg, from the product label.
GNC
See all GNC products- Name
- General Nutrition Corporation
- City
- Pittsburgh
- State
- PA
- ZipCode
- 15222
- Phone Number
- 1-888-462-2548
- Web Address
- gnc.com
CoQ-10 100 mg by GNC: Common Questions
Does CoQ-10 100 mg by GNC interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
I'm pregnant — is CoQ-10 safe?
I'm breastfeeding — can I take this?
What are the side effects I might experience?
Does CoQ-10 actually work for migraines?
Can I take this with my blood pressure medication?
What exactly is coenzyme Q-10?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if CoQ-10 100 mg is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind CoQ-10 100 mg’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
CoQ-10 100 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 40 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Coenzyme Q10 40 references
- Kamikawa T, Kobayashi A, Yamashita T, et al. Effects of coenzyme Q10 on exercise tolerance in chronic stable angina pectoris. Am J Cardiol 1985;56:247-51. PubMed
- Langsjoen P, Willis R, Folkers K. Treatment of essential hypertension with coenzyme Q10. Mol Aspects Med 1994;S265-72. PubMed
- Spigset O. Reduced effect of warfarin caused by ubidecarenone. Lancet 1994;334:1372-3. PubMed
- Singh RB, Niaz MA, Rastogi SS, et al. Effect of hydrosoluble coenzyme Q10 on blood pressures and insulin resistance in hypertensive patients with coronary artery disease. J Hum Hypertens 1999;13:203-8. PubMed
- Portakal O, Ozkaya O, Erden Inal M, et al. Coenzyme Q10 concentrations and antioxidant status in tissues of breast cancer patients. Clin Biochem 2000;33:279-84. PubMed
- Lund EL, Quistorff B, Spang-Thomsen M, Kristjansen PE. Effect of radiation therapy on small-cell lung cancer is reduced by ubiquinone intake. Folia Microbiol (Praha) 1998;43:505-6. PubMed
- Langsjoen PH, Langsjoen PH, Folkers K. Long-term efficacy and safety of coenzyme Q10 therapy for idiopathic dilated cardiomyopathy. Am J Cardiol 1990;65:521-3. PubMed
- Heck AM, DeWitt BA, Lukes AL. Potential interactions between alternative therapies and warfarin. Am J Health Syst Pharm 2000;57:1221-7. DOI
- Landbo C, Almdal TP. [Interaction between warfarin and coenzyme Q10]. Ugeskr Laeger 1998;160:3226-7.
- Baggio E, Gandini R, Plauncher AC, et al. Italian multicenter study on the safety and efficacy of coenzyme Q10 as adjunctive therapy in heart failure. CoQ10 Drug Surveillance Investigators. Mol Aspects Med 1994;15 Suppl:S287-94. PubMed
- Burke BE, Neuenschwander R, Olson RD. Randomized, double-blind, placebo-controlled trial of coenzyme Q10 in isolated systolic hypertension. South Med J 2001;94:1112-7. PubMed
- The Huntington Study Group. A randomized, placebo-controlled trial of coenzyme Q10 and remacemide in Huntington's disease. Neurology 2001;57:397-404.
- Hodgson JM, Watts GF, Playford DA, et al. Coenzyme Q10 improves blood pressure and glycaemic control: a controlled trial in subjects with type 2 diabetes. Eur J Clin Nutr 2002;56:1137-42. PubMed
- Singh RB, Neki NS, Kartikey K, et al. Effect of coenzyme Q10 on risk of atherosclerosis in patients with recent myocardial infarction. Mol Cell Biochem 2003;246:75-82. DOI
- Porterfield LM. Why did the response to warfarin change? RN 2000;63:107.
- Sandor PS, Di Clemente L, Coppola G, et al. Efficacy of coenzyme Q10 in migraine prophylaxis: A randomized controlled trial. Neurology 2005;64:713-5. PubMed
- Engelsen J, Nielsen JD, Winther K. Effect of coenzyme Q10 and Ginkgo biloba on warfarin dosage in stable, long-term warfarin treated outpatients. A randomised, double blind, placebo-crossover trial. Thromb Haemost 2002;87:1075-6. DOI
- Berman M, Erman A, Ben-Gal T, et al. Coenzyme Q10 in patients with end-stage heart failure awaiting cardiac transplantation: a randomized, placebo-controlled study. Clin Cardiol 2004;27:295–9. PubMed
- Storch A, Jost WH, Vieregge P, et al. Randomized, double-blind, placebo-controlled trial on symptomatic effects of coenzyme Q10 in Parkinson disease. Arch Neurol 2007;64:938-44. DOI
- Digiesi V, Cantini F, Oradei A, et al. Coenzyme Q10 in essential hypertension. Mol Aspects Med 1994;15 Suppl:s257-63. PubMed
- Yamagami T, Takagi M, Akagami H, et al. Effect of coenzyme Q10 on essential hypertension, a double blind controlled study. In: Folkers KA, Yamamura Y, eds. Biomedical and Clinical Aspects of Coenzyme Q, Vol. 5. Amsterdam: Elsevier Science Publications, 19
- Ho MJ, Bellusci A, Wright JM. Blood pressure lowering efficacy of coenzyme Q10 for primary hypertension (review). Cochrane Database Syst Rev 2009;(4):CD007435. PubMed
- Rosenfeldt, F. L., Haas, S. J., Krum, H., Hadj, A., Ng, K., Leong, J. Y., and Watts, G. F. Coenzyme Q10 in the treatment of hypertension: a meta-analysis of the clinical trials. J Hum.Hypertens. 2007;21(4):297-306. PubMed
- Stamelou, M., Reuss, A., Pilatus, U., Magerkurth, J., Niklowitz, P., Eggert, K. M., Krisp, A., Menke, T., Schade-Brittinger, C., Oertel, W. H., and Hoglinger, G. U. Short-term effects of coenzyme Q10 in progressive supranuclear palsy: a randomized, place DOI
- Keogh A, Fenton S, Leslie C, et al. Randomised double-blind, placebo-controlled trial of coenzyme Q, therapy in class II and III systolic heart failure. Heart Lung Circ. 2003;12:135-41.
- Gane, E. J., Weilert, F., Orr, D. W., Keogh, G. F., Gibson, M., Lockhart, M. M., Frampton, C. M., Taylor, K. M., Smith, R. A., and Murphy, M. P. The mitochondria-targeted anti-oxidant mitoquinone decreases liver damage in a phase II study of hepatitis C
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