Interactions on record — worth a quick check against your medications. Based on 2 of 3 ingredients. Check your meds →
Dietary supplement

Cordastra Ingredients & Drug Interactions

by Beachbody Nutritionals

Capsule Category: Other Combinations
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Cordastra is a dietary supplement by Beachbody Nutritionals with 3 active ingredients. Its ingredients are commonly taken for immune support, colds and flu, upper respiratory infections.Based on those ingredients, 336 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Cordyceps, Astragalus. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Cordastra by Beachbody Nutritionals

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 3 of its 3 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

Cordastra contains 3 active ingredients. Astragalus is a traditional plant used in Chinese medicine.

Cordyceps is a fungus that's been studied for potential energy and immune effects. The product also includes a Herbal Activating System, though we hold no interaction data for that ingredient.

The capsule itself contains inactive ingredients — hypromellose (the capsule shell), magnesium stearate, and silicon dioxide — which are fillers and binders with no active role.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use.

Why this rating?
  • The label markets this product for: Energy, stamina, and immune system support.
  • We looked for evidence on: Athletic performance, Fatigue, Chemotherapy-related fatigue, Post-stroke fatigue, Upper respiratory tract infection (URTI), Endurance — and 2 related terms.
  • The closest evidence on file: Cordyceps is rated "Possibly Ineffective" for Athletic performance (Natural Medicines).
  • Also on file: Cordyceps is rated "Insufficient Reliable Evidence To Rate" for Fatigue.
  • Also on file: Astragalus is rated "Insufficient Reliable Evidence To Rate" for Chemotherapy-related fatigue, Chronic fatigue syndrome (CFS), Upper respiratory tract infection (URTI), Post-stroke fatigue.

The evidence for what astragalus can do is incomplete: we have insufficient data to say whether it works for allergic rhinitis, amenorrhea, aplastic anemia, angina, asthma, or beta-thalassemia. Cordyceps shows a different picture — it appears ineffective for athletic performance, and we lack enough evidence to know if it helps sexual dysfunction, arrhythmias, asthma, lung cancer, or COPD.

Because the effectiveness ratings in our data don't establish clear benefit for any of these uses, you'll want to talk with your doctor about whether this product fits what you're trying to do.

The evidence, ingredient by ingredient Astragalus Cordyceps

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Astragalus is generally well tolerated short-term in healthy adults, but solid human safety data is limited. Cordyceps is also generally well tolerated when used for up to a year, though quality varies widely between products and evidence overall is thin.

The most common side effects from cordyceps are mild — abdominal discomfort, constipation, or diarrhea — and can sometimes be reduced by taking it with food. One case report linked a cordyceps-containing product to liver inflammation (hepatitis), though it's unclear whether cordyceps itself was to blame or if a contaminant caused it.

Both astragalus and cordyceps should be avoided during pregnancy and while breastfeeding — there isn't enough safety data either way to know they're okay in those situations. If you're pregnant, planning pregnancy, or nursing, talk with your doctor or pharmacist before using this product.

Side effects, ingredient by ingredient Astragalus Cordyceps

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 2 of the 2 matched ingredients can interact with medications — Cordyceps, Astragalus.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; immunosuppressants / transplant drugs; diabetes medications; lithium.
  • For scale: 336 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take Cordastra, check with your doctor or pharmacist if you take immunosuppressants (used after transplant or for autoimmune diseases) — astragalus may reduce how well they work. Also confirm your use if you're on blood thinners or antiplatelet drugs like warfarin or aspirin, diabetes medications, or lithium.

Astragalus could worsen low blood sugar risk or increase lithium levels, and cordyceps might raise bleeding risk. The Herbal Activating System ingredient has no interaction data we could check, so run your complete medication list through the tool below.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

Cordastra is worth a closer look if you're interested in immune support or energy, but the evidence for what it actually does is weak or absent. The bigger question is whether it will interfere with medications you take — especially if you're on blood thinners, diabetes drugs, immunosuppressants, or lithium.

Check your exact medications with the tool on this page, and talk it over with your doctor or pharmacist before you start, particularly if you're pregnant, breastfeeding, or managing a chronic condition.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Feb 25, 2015.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Cordastra, straight from the product label.

Brand Beachbody Nutritionals
Net contents 60 Capsule(s)
Market status On market
Date entered into DSLD Feb 25, 2015
DSLD ID 42098
Product type Other Combinations
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Cordastra by Beachbody Nutritionals, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
30
IngredientAmount% DV
Astragalus1000 mg--
Cordyceps50 mg--
Herbal Activating System40 mg--

Other ingredients: Hypromellose, Magnesium Stearate, Silicon Dioxide

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Helps promote: - Energy and stamina - Healthy immune system

WELLNESS nutrition

30-DAY SUPPLY

Made in USA.

TCENV0004 / SUTCA31101 Rev.12/08/11

FDA Statement of Identity

DIETARY SUPPLEMENT

Brand IP Statement(s)

(C) 2012 Beachbody, LLC. All rights reserved.

Beachbody, LLC, is the owner of the Cordastra, Beachbody Nutritionals, Beachbody, and Team Beachbody trademarks, and all related designs, copyrights, trademarks, and other intellectual property.

CORDASTRA(TM) supports daily wellness by naturally promoting a healthy immune system, energy, and stamina, especially during times of stress.

Precautions

WARNING: Consult with a healthcare professional prior to use if pregnant, breast feeding, providing to a child, or if you have other medical conditions.

WARNING: Consult with a healthcare professional prior to use if pregnant, breast feeding, providing to a child, or if you have other medical conditions. Keep out of reach of children.

ALLERGEN INFORMATION: Made in a facility that processes milk, eggs, fish, crustacean shellfish, tree nuts, wheat, peanuts, and soy.

Suggested/Recommended/Usage/Directions

Take daily for optimal health.

DIRECTIONS: As a dietary supplement, take 2 capsules daily with water.

Storage

STORAGE: Keep tightly closed in a cool, dry place.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

See for yourself

Cordastra by Beachbody Nutritionals label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Cordastra by Beachbody Nutritionals

These are the 3 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Astragalus

Interacts with
208 drugs
1000 mg per serving

Astragalus is a root used for centuries in traditional Chinese medicine, mainly to support the immune system and help the body cope with stress. While...

Astragalus monograph & interactions

Cordyceps

Interacts with
249 drugs
50 mg per serving

Cordyceps is a fungus used in traditional Chinese medicine for energy, exercise performance, and lung and immune support. Human research is limited an...

Cordyceps monograph & interactions

Herbal Activating System

40 mg per serving

Other (inactive) ingredients: Hypromellose, Magnesium Stearate, Silicon Dioxide. These complete the product’s ingredient list but are not active constituents.

Interaction report

Cordastra by Beachbody Nutritionals Drug Interactions

Want to check YOUR meds against Cordastra?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
336Drugs
328 Moderate 8 Minor

Ingredients driving the most interactions

Cordyceps 249

Each ingredient & the kinds of drugs it affects

For each ingredient in Cordastra with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Cordyceps3 drug types · 249 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, cordyceps may increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
In vitro and animal research suggests that cordyceps extract inhibits platelet aggregation and function. However, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Immunosuppressants

Theoretically, concurrent use of cordyceps might interfere with immunosuppressive therapy.
Animal and in vitro research suggests that cordyceps stimulates the immune system. However, limited clinical research suggests that taking cordyceps may lower the necessary therapeutic dose of the immunosuppressant cyclosporine, which suggests that cordyceps may have an immunosuppressive effect.

Likelihood Possible Evidence B
Testosterone

Theoretically, concurrent use of cordyceps and testosterone might have additive effects.
Animal research suggests that cordyceps can increase testosterone levels. The clinical significance of this finding is unclear.

Likelihood Possible Evidence D

Astragalus4 drug types · 208 drugs

Antidiabetes Drugs

Theoretically, taking astragalus with antidiabetes drugs might increase the risk of hypoglycemia.
Clinical research in humans shows that astragalus might have hypoglycemic effects. Theoretically, taking astragalus, especially in combination with other hypoglycemic agents, might increase the risk of hypoglycemia.

Likelihood Probable Evidence A
Cyclophosphamide

Theoretically, astragalus might interfere with cyclophosphamide therapy.
Evidence regarding the effect of astragalus on immunosuppression caused by cyclophosphamide is conflicting. Some animal research suggests that astragalus reverses cyclophosphamide-induced immunosuppression. However, other animal research shows no effect.

Likelihood Possible Evidence D
Immunosuppressants

Theoretically, astragalus might interfere with immunosuppressive therapy.
Astragalus seems to stimulate immune function. Theoretically, taking astragalus might decrease the effects of immunosuppressive therapy.

Likelihood Possible Evidence D
Lithium

Theoretically, astragalus might increase levels and adverse effects of lithium.
Animal research suggests that astragalus has diuretic properties. Theoretically, due to this diuretic effect, astragalus might reduce excretion and increase levels of lithium.

Likelihood Probable Evidence D
The maker

Brand information

Manufacturer and brand details for Cordastra, from the product label.

Beachbody Nutritionals

See all Beachbody Nutritionals products
Phone Number
1 (800) 818-5174
Pharmacist Counseling Corner

Cordastra by Beachbody Nutritionals: Common Questions

Does Cordastra by Beachbody Nutritionals interact with any medications?
Yes. Based on its ingredients, Cordastra has a known interaction with 336 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Cordastra contains 3 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take Cordastra if I'm pregnant or breastfeeding?
No — not enough safety data exists for either astragalus or cordyceps during pregnancy or breastfeeding. The safety data advises against it in both cases. Talk with your doctor or pharmacist before you take this product if you're pregnant, planning pregnancy, or nursing.
What are the most common side effects?
Cordyceps may cause mild stomach issues — abdominal discomfort, constipation, or diarrhea. These are uncommon and sometimes improve if you take cordyceps with food. Astragalus side effects are less well documented, but dizziness has been reported in studies, though it may not have been caused by the ingredient itself.
Is Cordastra proven to work?
The evidence isn't strong. For astragalus, we don't have enough reliable data to say it works for the conditions listed. Cordyceps appears ineffective for athletic performance and lacks solid evidence for other uses. Talk with your doctor about whether this product makes sense for what you're trying to achieve.
How long can I safely take Cordastra?
Cordyceps appears well tolerated for up to a year in research. Astragalus is considered generally well tolerated short-term in healthy adults, but long-term safety data is limited. If you plan to use this regularly, check with your pharmacist or doctor.
What does each ingredient do?
Astragalus is a traditional plant used in Chinese medicine. Cordyceps is a fungus studied for potential effects on energy and immune function. The Herbal Activating System is included in the formula, but we have no interaction or effectiveness data on file for it.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Cordastra is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Cordastra label
Sources

Sources & How We Checked

Cordastra's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 27 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Astragalus 13 references
  1. Upton R, ed. Astragalus Root: Analytical, quality control, and therapeutic monograph. Santa Cruz, CA: American Herbal Pharmacopoeia. 1999:1-25.
  2. Khoo KS, Ang PT. Extract of astragalus membranaceus and ligustrum lucidum does not prevent cyclophosphamide-induced myelosuppression. Singapore Med J 1995;36:387-90.
  3. Chu DT, Wong WL, Mavligit GM. Immunotherapy with Chinese medicinal herbs. II. Reversal of cyclophosphamide-induced immune suppression by administration of fractionated Astragalus membranaceus in vivo. J Clin Lab Immunol 1988;25:125-9.
  4. Sun Y, Hersh EM, Lee SL, et al. Preliminary observations on the effects of the Chinese medicinal herbs Astragalus membranaceus and Ligustrum lucidum on lymphocyte blastogenic responses. J Biol Response Mod 1983;2:227-37..
  5. Ma J, Peng A, Lin S. Mechanisms of the therapeutic effect of astragalus membranaceus on sodium and water retention in experimental heart failure. Chin Med J (Engl) 1998;111:17-23.
  6. Matkovic Z, Zivkovic V, Korica M, et al. Efficacy and safety of Astragalus membranaceus in the treatment of patients with seasonal allergic rhinitis. Phytother Res 2010;24:175-81.
  7. Zhang, J. G., Yang, N., He, H., Wei, G. H., Gao, D. S., Wang, X. L., Wang, X. Z., and Song, G. Y. [Effect of Astragalus injection on plasma levels of apoptosis-related factors in aged patients with chronic heart failure.]. Chin J Integr.Med 2005;11(3):18 PubMed
  8. Chen, H. W., Lin, I. H., Chen, Y. J., Chang, K. H., Wu, M. H., Su, W. H., Huang, G. C., and Lai, Y. L. A novel infusible botanically-derived drug, PG2, for cancer-related fatigue: a phase II double-blind, randomized placebo-controlled study. Clin Invest PubMed
  9. Tian H, Lu J, He H, et al.The effect of Astragalus as an adjuvant treatment in type 2 diabetes mellitus: A (preliminary) meta-analysis. J Ethnopharmacol. 2016;191:206-215. doi: 10.1016/j.jep.2016.05.062. PubMed
  10. Hong KF, Liu PY, Zhang W, Gui DK, Xu YH. The Efficacy and Safety of Astragalus as an Adjuvant Treatment for Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis. J Integr Complement Med 2023. PubMed
  11. Chan KW, Kwong ASK, Tsui PN, et al. Add-on astragalus in type 2 diabetes and chronic kidney disease: A multi-center, assessor-blind, randomized controlled trial. Phytomedicine 2024;130:155457. PubMed
  12. Han X, Yu T, Chen X, Du Z, Yu M, Xiong J. Effect of Astragalus membranaceus on left ventricular remodeling in HFrEF: a systematic review and meta-analysis. Front Pharmacol 2024;15:1345797. PubMed
  13. Jing P, Hongzheng H, Zhenqi WU, Meijuan Z, Zuojing LI, Gang C. Long-term efficacy and safety of Huangqi ()-based Traditional Chinese Medicine in diabetic peripheral neuropathy: a Meta-analysis of randomized controlled trials. J Tradit Chin Med 2024;44(2):

See these in context on the Astragalus monograph →

Cordyceps 14 references
  1. Zhu JS, Halpern GM, Jones K. The scientific rediscovery of an ancient Chinese herbal medicine: Cordyceps sinensis: part I. J Altern Complement Med 1998;4:289-303.
  2. Zhu JS, Halpern GM, Jones K. The scientific rediscovery of a precious ancient Chinese herbal regimen: Cordyceps sinensis: part II. J Altern Complement Med 1998;4:429-57.
  3. Chen YJ, Shiao MS, Lee SS, Wang SY. Effect of Cordyceps sinensis on the proliferation and differentiation of human leukemic U937 cells. Life Sci 1997;60:2349-59. PubMed
  4. Zhao Y. [Inhibitory effects of alcoholic extract of Cordyceps sinensis on abdominal aortic thrombus formation in rabbits]. Chung Hua I Hsueh Tsa Chih (Taipei) 1991;71:612-5, 42.
  5. Chen GZ, Chen GL, Sun T, et al. Effects of Cordyceps sinensis on murine T lymphocyte subsets. Chin Med J (English) 1991;104:4-8.
  6. Zhu XY, Yu HY. [Immunosuppressive effect of cultured Cordyceps sinensis on cellular immune response]. Chung Hsi I Chieh Ho Tsa Chih 1990;10:485-7, 454.
  7. Hsu, C. C., Huang, Y. L., Tsai, S. J., Sheu, C. C., and Huang, B. M. In vivo and in vitro stimulatory effects of Cordyceps sinensis on testosterone production in mouse Leydig cells. Life Sci 9-5-2003;73(16):2127-2136. PubMed
  8. Ikumoto, T., Sasaki, S., Namba, H., Toyama, R., Moritoki, H., and Mouri, T. [Physiologically active compounds in the extracts from tochukaso and cultured mycelia of Cordyceps and Isaria]. Yakugaku Zasshi 1991;111(9):504-509. PubMed
  9. Wu, T. N., Yang, K. C., Wang, C. M., Lai, J. S., Ko, K. N., Chang, P. Y., and Liou, S. H. Lead poisoning caused by contaminated Cordyceps, a Chinese herbal medicine: two case reports. Sci.Total Environ. 4-5-1996;182(1-3):193-195. PubMed
  10. Hong T, Zhang M, Fan J. Cordyceps sinensis (a traditional Chinese medicine) for kidney transplant recipients (Review). Cochrane Database Syst Rev. 2015;(10):CD009698. doi: 10.1002/14651858.CD009698.pub2.
  11. Zhang HW, Lin ZX, Tung YS, Kwan TH, Mok CK, Leung C, Chan LS. Cordyceps sinensis (a traditional Chinese medicine) for treating chronic kidney disease (Review). Cochrane Database Syst Rev. 2014;(12):CD008353. doi: 10.1002/14651858.CD008353.pub2. PubMed
  12. Bee Yean O, Zoriah A. Efficacy of Cordyceps sinensis as an adjunctive treatment in hemodialysis patients: a systematic review and Meta-analysis. J Tradit Chin Med. 2019;39(1):1-14.
  13. Thurian D, Montani M, Stickel F. Drug-induced, mixed-type hepatitis following ingestion of Cordyceps sinensis. Int J Clin Pharmacol Ther 2022;60(2):115-120. PubMed
  14. Yu X, Mao Y, Shergis JL, et al. Effectiveness and safety of oral Cordyceps sinensis on stable COPD of GOLD stages 2-3: Systematic review and meta-analysis. Evid Based Complement Alternat Med. 2019;2019:4903671.

See these in context on the Cordyceps monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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