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Dietary supplement

Cordyceps 1000 mg Ingredients & Drug Interactions

by Nature's Way

Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Cordyceps 1000 mg is a dietary supplement by Nature's Way with 1 active ingredient. Its ingredients are commonly taken for fatigue and low energy, athletic performance and stamina, respiratory and lung support.Based on those ingredients, 249 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Cordyceps (Cordyceps militaris) Mushroom. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Cordyceps 1000 mg by Nature's Way

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: cordyceps mushroom (Cordyceps militaris). The capsule also holds inactive ingredients—silica and cellulose as binders and fillers, and a plant-derived capsule shell.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Cordyceps's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: traditionally used for vitality and endurance.
  • We looked for evidence on: Athletic performance, Fatigue, stamina, energy.
  • The closest evidence on file: Cordyceps is rated "Possibly Ineffective" for Athletic performance (Natural Medicines).
  • Also on file: Cordyceps is rated "Insufficient Reliable Evidence To Rate" for Fatigue.

The evidence on cordyceps is mixed and mostly limited. For athletic performance, the data suggests it's possibly ineffective.

For sexual dysfunction, asthma, COPD, arrhythmia, and lung cancer, there isn't enough reliable evidence in our data to say whether it works or not. If you're considering cordyceps for any of these uses, it's worth talking to your doctor about what the current research actually supports.

The evidence, ingredient by ingredient Cordyceps

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Cordyceps is generally well tolerated when taken short-term, though the long-term safety record is thin and product quality can vary a lot. The most common side effects from studies are mild—abdominal discomfort, diarrhea, and constipation—and often improve if you take it after eating.

Dry mouth and throat discomfort have also been reported but are uncommon. One case report describes hepatitis (liver inflammation) that may have been linked to a cordyceps product, though it's unclear whether cordyceps itself or a contaminant was responsible; the person recovered once they stopped.

There isn't enough safety data to use cordyceps during pregnancy or while breastfeeding. If you're pregnant, nursing, or planning to become pregnant, talk with your doctor or pharmacist before taking this.

Side effects, ingredient by ingredient Cordyceps

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Cordyceps.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; immunosuppressants / transplant drugs.
  • For scale: 249 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking Cordyceps 1000 mg, check with your doctor or pharmacist if you take blood thinners (anticoagulants or antiplatelet drugs like warfarin or aspirin), immune-suppressing medications (such as cyclosporine), or testosterone supplements or hormone therapy. No interactions are documented for other drug types in our data, but your pharmacist can help you review your complete medication list.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

Cordyceps is a single-ingredient supplement generally well tolerated short-term, but the evidence for what it actually does is weak or absent for most uses. The main medication concerns are blood thinners, immune-suppressing drugs, and testosterone.

If you take any prescription medication, check your exact drugs with the search tool on this page, then confirm with your doctor or pharmacist before starting.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jan 7, 2019.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Cordyceps 1000 mg, straight from the product label.

Brand Nature's Way
Barcode (UPC) 033674153840
Net contents 60 Vegetarian Capsule(s)
Market status On market
Date entered into DSLD Jan 7, 2019
DSLD ID 184369
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Cordyceps 1000 mg by Nature's Way, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
30
UPC/BARCODE
033674153840
IngredientAmount% DV
Total Carbohydrates1 Gram(s)1%
Cordyceps (Cordyceps militaris) Mushroom1 Gram(s)--

Other ingredients: plant-derived Capsule, Silica, Cellulose

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Traditionally used for vitality & endurance

Premium herbal

1000mg per serving

Formula

Derived from the Latin word meaning club head, Nature's Way Cordyceps are grown in the United States and routinely tested for superior quality standards.

Precautions

Keep out of reach of children.

Safety sealed with printed outer shrink-wrap and inner seal. Do not use if either is broken or missing.

If pregnant, nursing, or taking any medications, consult a healthcare professional before use.

Formulation

Gluten free. No sugar, salt, yeast, wheat, corn, soy, dairy products, artificial colors, flavors, or preservatives.

Vegan

Seals/Symbols

Vegan

Certified Authentic Tru-ID

General

LG15384.A01 BLK8303A

FDA Disclaimer Statement

These statements have not been evaluated by the Food & Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Recommendation: Take 2 capsules twice daily with food or water.

Brand IP Statement(s)

2018 Nature's Way Brands, LLC

See for yourself

Cordyceps 1000 mg by Nature's Way label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Cordyceps 1000 mg by Nature's Way

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size2 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

1 Gram(s) per serving

Cordyceps is a fungus used in traditional Chinese medicine for energy, exercise performance, and lung and immune support. Human research is limited an...

Cordyceps (Cordyceps militaris) Mushroom monograph & interactions

Other (inactive) ingredients: Plant-derived Capsule, Silica, Cellulose. These complete the product’s ingredient list but are not active constituents.

Interaction report

Cordyceps 1000 mg by Nature's Way Drug Interactions

Want to check YOUR meds against Cordyceps 1000 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
249Drugs
241 Moderate 8 Minor

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Cordyceps 1000 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Cordyceps (Cordyceps militaris) Mushroom3 drug types · 249 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, cordyceps may increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
In vitro and animal research suggests that cordyceps extract inhibits platelet aggregation and function. However, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Immunosuppressants

Theoretically, concurrent use of cordyceps might interfere with immunosuppressive therapy.
Animal and in vitro research suggests that cordyceps stimulates the immune system. However, limited clinical research suggests that taking cordyceps may lower the necessary therapeutic dose of the immunosuppressant cyclosporine, which suggests that cordyceps may have an immunosuppressive effect.

Likelihood Possible Evidence B
Testosterone

Theoretically, concurrent use of cordyceps and testosterone might have additive effects.
Animal research suggests that cordyceps can increase testosterone levels. The clinical significance of this finding is unclear.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Cordyceps 1000 mg, from the product label.

Nature's Way

See all Nature's Way products
Name
Nature's Way Brands, LLC
City
Green Bay
State
WI
ZipCode
54311
Phone Number
1-800-962-8873
Web Address
naturesway.com
Pharmacist Counseling Corner

Cordyceps 1000 mg by Nature's Way: Common Questions

Does Cordyceps 1000 mg by Nature's Way interact with any medications?
Yes. Based on its ingredients, Cordyceps 1000 mg has a known interaction with 249 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Cordyceps 1000 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take cordyceps if I'm pregnant or breastfeeding?
There isn't enough safety data to know either way. The safety data available advises against using it during pregnancy and while breastfeeding. Talk with your doctor or pharmacist for advice tailored to your situation.
What side effects might I get from cordyceps?
Most common are mild stomach issues—abdominal discomfort, diarrhea, and constipation. Some people report dry mouth or throat discomfort, but these are uncommon. These effects are usually mild and may improve if you take it after eating rather than on an empty stomach.
Does cordyceps actually work for athletic performance?
The evidence suggests it's likely ineffective for athletic performance. For other uses like sexual function or lung conditions, there isn't enough reliable research in our data to say whether it works.
How long is it safe to take cordyceps?
Research shows cordyceps is generally well tolerated for up to 1 year. Beyond that, the safety evidence is limited. If you're considering long-term use, ask your pharmacist what's known.
Why does the product have silica and cellulose in it?
These are inactive ingredients—binders and fillers that help hold the capsule together and give it shape. They're not the active part; cordyceps mushroom is what you're taking it for.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Cordyceps 1000 mg is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Cordyceps 1000 mg label
Sources

Sources & How We Checked

Cordyceps 1000 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 14 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Cordyceps 14 references
  1. Zhu JS, Halpern GM, Jones K. The scientific rediscovery of an ancient Chinese herbal medicine: Cordyceps sinensis: part I. J Altern Complement Med 1998;4:289-303.
  2. Zhu JS, Halpern GM, Jones K. The scientific rediscovery of a precious ancient Chinese herbal regimen: Cordyceps sinensis: part II. J Altern Complement Med 1998;4:429-57.
  3. Chen YJ, Shiao MS, Lee SS, Wang SY. Effect of Cordyceps sinensis on the proliferation and differentiation of human leukemic U937 cells. Life Sci 1997;60:2349-59. PubMed
  4. Zhao Y. [Inhibitory effects of alcoholic extract of Cordyceps sinensis on abdominal aortic thrombus formation in rabbits]. Chung Hua I Hsueh Tsa Chih (Taipei) 1991;71:612-5, 42.
  5. Chen GZ, Chen GL, Sun T, et al. Effects of Cordyceps sinensis on murine T lymphocyte subsets. Chin Med J (English) 1991;104:4-8.
  6. Zhu XY, Yu HY. [Immunosuppressive effect of cultured Cordyceps sinensis on cellular immune response]. Chung Hsi I Chieh Ho Tsa Chih 1990;10:485-7, 454.
  7. Hsu, C. C., Huang, Y. L., Tsai, S. J., Sheu, C. C., and Huang, B. M. In vivo and in vitro stimulatory effects of Cordyceps sinensis on testosterone production in mouse Leydig cells. Life Sci 9-5-2003;73(16):2127-2136. PubMed
  8. Ikumoto, T., Sasaki, S., Namba, H., Toyama, R., Moritoki, H., and Mouri, T. [Physiologically active compounds in the extracts from tochukaso and cultured mycelia of Cordyceps and Isaria]. Yakugaku Zasshi 1991;111(9):504-509. PubMed
  9. Wu, T. N., Yang, K. C., Wang, C. M., Lai, J. S., Ko, K. N., Chang, P. Y., and Liou, S. H. Lead poisoning caused by contaminated Cordyceps, a Chinese herbal medicine: two case reports. Sci.Total Environ. 4-5-1996;182(1-3):193-195. PubMed
  10. Hong T, Zhang M, Fan J. Cordyceps sinensis (a traditional Chinese medicine) for kidney transplant recipients (Review). Cochrane Database Syst Rev. 2015;(10):CD009698. doi: 10.1002/14651858.CD009698.pub2.
  11. Zhang HW, Lin ZX, Tung YS, Kwan TH, Mok CK, Leung C, Chan LS. Cordyceps sinensis (a traditional Chinese medicine) for treating chronic kidney disease (Review). Cochrane Database Syst Rev. 2014;(12):CD008353. doi: 10.1002/14651858.CD008353.pub2. PubMed
  12. Bee Yean O, Zoriah A. Efficacy of Cordyceps sinensis as an adjunctive treatment in hemodialysis patients: a systematic review and Meta-analysis. J Tradit Chin Med. 2019;39(1):1-14.
  13. Thurian D, Montani M, Stickel F. Drug-induced, mixed-type hepatitis following ingestion of Cordyceps sinensis. Int J Clin Pharmacol Ther 2022;60(2):115-120. PubMed
  14. Yu X, Mao Y, Shergis JL, et al. Effectiveness and safety of oral Cordyceps sinensis on stable COPD of GOLD stages 2-3: Systematic review and meta-analysis. Evid Based Complement Alternat Med. 2019;2019:4903671.

See these in context on the Cordyceps monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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