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Dietary supplement

Cordyceps Mushroom Ingredients & Drug Interactions

by Fresh Nutrition

Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Cordyceps Mushroom is a dietary supplement by Fresh Nutrition with 1 active ingredient. Its ingredients are commonly taken for fatigue and low energy, athletic performance and stamina, respiratory and lung support.Based on those ingredients, 249 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are organic Cordyceps Mushroom. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Cordyceps Mushroom by Fresh Nutrition

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: organic cordyceps mushroom, a fungus traditionally used to support energy and stamina. The capsule itself is made from vegetarian material (an inactive ingredient).

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Cordyceps's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: Cordyceps mushroom for energy and immune support.
  • We looked for evidence on: Fatigue, Athletic performance, Asthma, Cough, stamina, endurance — and 1 related terms.
  • The closest evidence on file: Cordyceps is rated "Possibly Ineffective" for Athletic performance (Natural Medicines).
  • Also on file: Cordyceps is rated "Insufficient Reliable Evidence To Rate" for Asthma, Cough, Fatigue.

The evidence for cordyceps is mixed. For athletic performance, current data suggests it's possibly ineffective.

For sexual dysfunction, asthma, arrhythmia (irregular heartbeat), chronic obstructive pulmonary disease (COPD), and lung cancer, there simply isn't enough reliable evidence to say whether it works or doesn't. If you're considering cordyceps for any of these reasons, the science doesn't yet back it up.

The evidence, ingredient by ingredient Cordyceps

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Cordyceps is generally well tolerated when taken for up to a year, though the overall safety data is limited and product quality varies widely between brands. The most common side effects are mild—abdominal discomfort, constipation, or diarrhea—and these are uncommon; taking it with food may help reduce them.

There's one case report of liver inflammation (cholestasis) in someone taking a cordyceps product, but it's unclear whether cordyceps itself was the cause or a contaminant in that particular supplement. Because there isn't enough safety data, the evidence advises against cordyceps during pregnancy and while breastfeeding.

Talk with your doctor or pharmacist about whether it's right for you.

Side effects, ingredient by ingredient Cordyceps

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Cordyceps.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; immunosuppressants / transplant drugs.
  • For scale: 249 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, check with your doctor or pharmacist if you're on blood thinners or antiplatelet drugs (a moderate interaction), immunosuppressants (moderate), or testosterone therapy (minor). No interactions are documented for the ingredient we could check beyond those listed.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

Cordyceps may be worth considering if you're interested in a traditional energy supplement, but the evidence for athletic performance or other health claims isn't strong. If you take blood thinners, immunosuppressants, or testosterone therapy, you'll want to check with your doctor or pharmacist before starting.

Given the gaps in safety data, it's best to skip it during pregnancy or while breastfeeding.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Feb 25, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Cordyceps Mushroom, straight from the product label.

Brand Fresh Nutrition
Barcode (UPC) 851039008044
Net contents 90 Capsule(s)
Market status On market
Date entered into DSLD Feb 25, 2021
DSLD ID 241923
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Cordyceps Mushroom by Fresh Nutrition, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
3 Capsule(s)
Maximum serving Sizes:
3 Capsule(s)
Servings per container
30
UPC/BARCODE
851039008044
IngredientAmount% DV
organic Cordyceps Mushroom1500 mg--

Other ingredients: Vegetarian Capsules

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Vegan

Non GMO Gluten free Soy free

Cordyceps Mushroom A fungus that has been used by traditional Chinese herbalists for its energizing and adaptogenic properties for centuries. Scientific studies have shown that Cordyceps may support a healthy immune system and promote normal vascular function also act as anti-oxidant, immunopotentiation, andti-tumor and hypo-glycemic activity.

No artificial colors, no artificial flavors, no preservatives, gluten-free Made with Non-GMO, all natural ingredients!

Natural detox Natural immune support Diabetes & blood sugar support Adrenal health enhanced Healthy vascular function

Carefully sourced from the world's largest Cordyceps cultivator. Fresh Nutrition produces the most potent Cordyceps products. The QC Lab at Fresh Nutrition verifies the Pure Cordyceps with a DNA profile, proving a 100% exactly matching the wild Cordyceps!

Quality Verified Third Party Tested For Quality And Purity To provide our consumers with complete confidence in our product quality, every batch is 3rd party tested for quality & purity.

General Statements

Fresh Nutrition Our goal has been to create a range of high-quality, natural products, using responsibly sourced materials to optimize health and well-being.

All natural

Appreciate to choose the best Cordyceps with affordable price through Fresh Nutrition.

Suggested/Recommended/Usage/Directions

Recommended Dosage: 3 capsules daily

Formula

Made with Non-GMO, all natural ingredients!

Made with organic cordyceps

Seals/Symbols

CCOF California Certified Organic Farmers Non GMO Project Verified nongmoproject.org

Made in USA

FDA Statement of Identity

Dietary Supplement

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

See for yourself

Cordyceps Mushroom by Fresh Nutrition label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Cordyceps Mushroom by Fresh Nutrition

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size3 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Organic Cordyceps Mushroom

Interacts with
249 drugs
1500 mg per serving

Cordyceps is a fungus used in traditional Chinese medicine for energy, exercise performance, and lung and immune support. Human research is limited an...

Organic Cordyceps Mushroom monograph & interactions

Other (inactive) ingredients: Vegetarian Capsules. These complete the product’s ingredient list but are not active constituents.

Interaction report

Cordyceps Mushroom by Fresh Nutrition Drug Interactions

Want to check YOUR meds against Cordyceps Mushroom?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
249Drugs
241 Moderate 8 Minor

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Cordyceps Mushroom with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

organic Cordyceps Mushroom3 drug types · 249 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, cordyceps may increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
In vitro and animal research suggests that cordyceps extract inhibits platelet aggregation and function. However, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Immunosuppressants

Theoretically, concurrent use of cordyceps might interfere with immunosuppressive therapy.
Animal and in vitro research suggests that cordyceps stimulates the immune system. However, limited clinical research suggests that taking cordyceps may lower the necessary therapeutic dose of the immunosuppressant cyclosporine, which suggests that cordyceps may have an immunosuppressive effect.

Likelihood Possible Evidence B
Testosterone

Theoretically, concurrent use of cordyceps and testosterone might have additive effects.
Animal research suggests that cordyceps can increase testosterone levels. The clinical significance of this finding is unclear.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Cordyceps Mushroom, from the product label.

Fresh Nutrition

See all Fresh Nutrition products
Name
Fresh Nutrition Inc.
Street Address
5305 River Rd North
City
Keizer
State
OR
ZipCode
97303
Web Address
www.fresh-nutrition.com
Pharmacist Counseling Corner

Cordyceps Mushroom by Fresh Nutrition: Common Questions

Does Cordyceps Mushroom by Fresh Nutrition interact with any medications?
Yes. Based on its ingredients, Cordyceps Mushroom has a known interaction with 249 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Cordyceps Mushroom contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is cordyceps safe to take during pregnancy?
No, there isn't enough safety data to know, so the evidence advises against it. Talk with your doctor or pharmacist for personalized advice.
Can I breastfeed while taking cordyceps?
The safety data isn't there to say it's safe while breastfeeding, so it's best avoided. Check with your doctor or pharmacist for guidance on your situation.
Does cordyceps actually help athletic performance?
The current evidence suggests it's possibly ineffective for athletic performance. If you're looking for a supplement to boost workout results, this one isn't backed by strong science.
What are the side effects?
Most people tolerate it well, but some experience mild abdominal discomfort, constipation, or diarrhea—and these are uncommon. Taking it with food may help. There's one case report of liver inflammation, though it's unclear if cordyceps was the cause.
Can I take cordyceps if I'm on warfarin or another blood thinner?
Lab research suggests cordyceps might slow blood clotting, which could increase bleeding risk with these drugs. Don't start it without checking with your doctor or pharmacist first.
Does quality vary between brands?
Yes—product quality varies widely, so you may want to research the brand you're considering and look for third-party testing if available.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Cordyceps Mushroom is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Cordyceps Mushroom label
Sources

Sources & How We Checked

Cordyceps Mushroom's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 14 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Cordyceps 14 references
  1. Zhu JS, Halpern GM, Jones K. The scientific rediscovery of an ancient Chinese herbal medicine: Cordyceps sinensis: part I. J Altern Complement Med 1998;4:289-303.
  2. Zhu JS, Halpern GM, Jones K. The scientific rediscovery of a precious ancient Chinese herbal regimen: Cordyceps sinensis: part II. J Altern Complement Med 1998;4:429-57.
  3. Chen YJ, Shiao MS, Lee SS, Wang SY. Effect of Cordyceps sinensis on the proliferation and differentiation of human leukemic U937 cells. Life Sci 1997;60:2349-59. PubMed
  4. Zhao Y. [Inhibitory effects of alcoholic extract of Cordyceps sinensis on abdominal aortic thrombus formation in rabbits]. Chung Hua I Hsueh Tsa Chih (Taipei) 1991;71:612-5, 42.
  5. Chen GZ, Chen GL, Sun T, et al. Effects of Cordyceps sinensis on murine T lymphocyte subsets. Chin Med J (English) 1991;104:4-8.
  6. Zhu XY, Yu HY. [Immunosuppressive effect of cultured Cordyceps sinensis on cellular immune response]. Chung Hsi I Chieh Ho Tsa Chih 1990;10:485-7, 454.
  7. Hsu, C. C., Huang, Y. L., Tsai, S. J., Sheu, C. C., and Huang, B. M. In vivo and in vitro stimulatory effects of Cordyceps sinensis on testosterone production in mouse Leydig cells. Life Sci 9-5-2003;73(16):2127-2136. PubMed
  8. Ikumoto, T., Sasaki, S., Namba, H., Toyama, R., Moritoki, H., and Mouri, T. [Physiologically active compounds in the extracts from tochukaso and cultured mycelia of Cordyceps and Isaria]. Yakugaku Zasshi 1991;111(9):504-509. PubMed
  9. Wu, T. N., Yang, K. C., Wang, C. M., Lai, J. S., Ko, K. N., Chang, P. Y., and Liou, S. H. Lead poisoning caused by contaminated Cordyceps, a Chinese herbal medicine: two case reports. Sci.Total Environ. 4-5-1996;182(1-3):193-195. PubMed
  10. Hong T, Zhang M, Fan J. Cordyceps sinensis (a traditional Chinese medicine) for kidney transplant recipients (Review). Cochrane Database Syst Rev. 2015;(10):CD009698. doi: 10.1002/14651858.CD009698.pub2.
  11. Zhang HW, Lin ZX, Tung YS, Kwan TH, Mok CK, Leung C, Chan LS. Cordyceps sinensis (a traditional Chinese medicine) for treating chronic kidney disease (Review). Cochrane Database Syst Rev. 2014;(12):CD008353. doi: 10.1002/14651858.CD008353.pub2. PubMed
  12. Bee Yean O, Zoriah A. Efficacy of Cordyceps sinensis as an adjunctive treatment in hemodialysis patients: a systematic review and Meta-analysis. J Tradit Chin Med. 2019;39(1):1-14.
  13. Thurian D, Montani M, Stickel F. Drug-induced, mixed-type hepatitis following ingestion of Cordyceps sinensis. Int J Clin Pharmacol Ther 2022;60(2):115-120. PubMed
  14. Yu X, Mao Y, Shergis JL, et al. Effectiveness and safety of oral Cordyceps sinensis on stable COPD of GOLD stages 2-3: Systematic review and meta-analysis. Evid Based Complement Alternat Med. 2019;2019:4903671.

See these in context on the Cordyceps monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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