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Dietary supplement

Cordyceps Mushroom Ingredients & Drug Interactions

by Natgrown

Cordyceps Mushroom label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 30, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Cordyceps Mushroom against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Cordyceps Mushroom is a dietary supplement by Natgrown with 1 active ingredient. Its ingredients are commonly taken for fatigue and low energy, athletic performance and stamina, respiratory and lung support.Based on those ingredients, 249 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Cordyceps Mushroom extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Cordyceps Mushroom by Natgrown

Ask about any prescription or over-the-counter medication and we check it for interactions with Cordyceps Mushroom by Natgrown — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Cordyceps Mushroom by Natgrown

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 16, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

Natgrown Cordyceps Mushroom is a single-ingredient product: cordyceps mushroom extract in capsule form. The capsule itself contains vegetable cellulose, magnesium stearate, and rice flour as inactive ingredients (the stuff that holds it together and makes the capsule work).

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Cordyceps product and its label doesn't state a use — see Cordyceps's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence for cordyceps is mixed and often thin. For athletic performance, the data suggests it's probably ineffective.

For sexual dysfunction, asthma, arrhythmia (heart rhythm problems), chronic obstructive pulmonary disease (COPD), and lung cancer, we don't have enough reliable evidence to say either way. That doesn't mean it doesn't work for these conditions — just that the research isn't solid enough yet to rate it.

The evidence, ingredient by ingredient Cordyceps

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Cordyceps is generally well tolerated when used for up to a year, though the safety evidence is limited and product quality varies a lot between brands. The most common side effects are mild: abdominal discomfort, constipation, diarrhea, dry mouth, and throat discomfort — and these are uncommon.

Taking it with food can help reduce stomach upset. There is one case report of liver inflammation (hepatitis) in someone taking a cordyceps product, but it's unclear whether cordyceps itself caused it or a contaminant did.

The safety data advises against cordyceps during pregnancy and breastfeeding because there simply isn't enough information to know it's safe.

Side effects, ingredient by ingredient Cordyceps

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Cordyceps.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; immunosuppressants / transplant drugs.
  • For scale: 249 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take Natgrown Cordyceps Mushroom, double-check with your doctor or pharmacist if you're on blood thinners or antiplatelet drugs (like warfarin, clopidogrel, or aspirin for heart health) — cordyceps may raise bleeding risk. Also check if you take immunosuppressants (drugs used after transplant or for certain autoimmune conditions) — cordyceps might interfere with how well they work.

Finally, if you're on testosterone therapy, mention cordyceps since animal research hints they could have additive effects.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Cordyceps might appeal to you if you're curious about traditional uses for energy or sexual function, but the evidence for those purposes is either lacking or suggests it doesn't work well. It's best known for a theoretical risk of bleeding with blood thinners and a possible interaction with immune-suppressing medications.

If you take any prescription medications — especially anticoagulants, antiplatelet drugs, or immunosuppressants — talk with your doctor or pharmacist before starting it.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Oct 22, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Cordyceps Mushroom, straight from the product label.

Brand Natgrown
Barcode (UPC) X002L3E5Y7
Net contents 120 Veggie Capsule(s)
Market status On market
Date entered into DSLD Oct 22, 2021
DSLD ID 259737
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Cordyceps Mushroom by Natgrown, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Veggie Capsule(s)
Maximum serving Sizes:
2 Veggie Capsule(s)
Servings per container
60
UPC/BARCODE
X002L3E5Y7
IngredientAmount% DV
Cordyceps Mushroom extract1000 mg--

Other ingredients: Vegetable Cellulose, Magnesium Stearate, Rice Flour

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested use: as a dietary supplement, take two (2) capsules once a day with food and a full glass of water. Best when taken as directed by a qualified healthcare professional.

Precautions

Caution: Do not exceed the recommended dose.

Pregnant or nursing mothers, children under the age of 18, and individuals with a known medical condition should consult a physician before using this or any dietary supplement. Keep out of reach of children.

Pregnant or nursing mothers, children under the age of 18, and individuals with a known medical condition should consult a physician before using this or any dietary supplement.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, or prevent any disease.

Seals/Symbols

GMP Good Manufacturing Practice Consistent Quality Made in USA

Formulation

100% Natural GMO free

Manufactured and quality tested in the USA Ingredients carefully sourced from around the world

Energy Support Traditionally for vitality, and endurance. Supports healthy immune system.

Zero gluten, milk, soy, eggs, shellfish, tree nuts, peanuts & wheat

Formula

Cordyceps Mushrooms 1000 mg per serving

FDA Statement of Identity

Dietary Supplement

General Statements

To reorder go to www.NATGROWN.com Lot number & expiration date printed on bottom of bottle

6 67061 79676 7

Brand IP Statement(s)

NATGROWN is a registered trademark

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Cordyceps Mushroom by Natgrown label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Cordyceps Mushroom label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Cordyceps Mushroom by Natgrown

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size2 Veggie Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.

Cordyceps Mushroom extract

Interacts with
249 drugs
1000 mg per serving

Cordyceps is a fungus used in traditional Chinese medicine for energy, exercise performance, and lung and immune support. Human research is limited an...

Cordyceps Mushroom extract monograph & interactions

Other (inactive) ingredients: Vegetable Cellulose, Magnesium Stearate, Rice Flour. These complete the product’s ingredient list but are not active constituents.

Interaction report

Cordyceps Mushroom by Natgrown Drug Interactions

Want to check YOUR meds against Cordyceps Mushroom?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
249Drugs
241 Moderate 8 Minor

Ingredients driving the most interactions

Cordyceps Mushroom extract 249

Individual Drug Interactions

The ingredients in Cordyceps Mushroom interact with 249 drugs. Click any drug to see the details.

1 of the 1 ingredient in Cordyceps Mushroom interact with drugs. Each result below shows which ingredient is responsible. Cordyceps Mushroom extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Cordyceps Mushroom with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Cordyceps Mushroom extract3 drug types · 249 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, cordyceps may increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
In vitro and animal research suggests that cordyceps extract inhibits platelet aggregation and function. However, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Immunosuppressants

Theoretically, concurrent use of cordyceps might interfere with immunosuppressive therapy.
Animal and in vitro research suggests that cordyceps stimulates the immune system. However, limited clinical research suggests that taking cordyceps may lower the necessary therapeutic dose of the immunosuppressant cyclosporine, which suggests that cordyceps may have an immunosuppressive effect.

Likelihood Possible Evidence B
Testosterone

Theoretically, concurrent use of cordyceps and testosterone might have additive effects.
Animal research suggests that cordyceps can increase testosterone levels. The clinical significance of this finding is unclear.

Likelihood Possible Evidence D
Cordyceps Mushroom extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Cordyceps Mushroom, from the product label.

Natgrown

See all Natgrown products
Name
GSD & Company, Inc.
City
West Palm Beach
State
FL
Web Address
www.NATGROWN.com
Pharmacist Counseling Corner

Cordyceps Mushroom by Natgrown: Common Questions

Does Cordyceps Mushroom by Natgrown interact with any medications?
Yes. Based on its ingredients, Cordyceps Mushroom has a known interaction with 249 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Cordyceps Mushroom contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does cordyceps actually work for energy and athletic performance?
For athletic performance specifically, the research suggests cordyceps is probably ineffective. For energy in general, we don't have enough solid evidence to say. You might see cordyceps marketed for both, but the data doesn't back those claims well.
Is it safe to take cordyceps if I'm pregnant or breastfeeding?
The safety data advises against it during both pregnancy and breastfeeding because there isn't enough information to know either way. Talk with your doctor or pharmacist about what's right for you in those situations.
What side effects might I get from cordyceps?
Most people tolerate it well, but the most common side effects are mild: abdominal discomfort, constipation, diarrhea, dry mouth, and throat discomfort — and these are uncommon. Taking it with food can help reduce stomach upset. Long-term safety evidence is limited.
I've heard cordyceps is from a rare mushroom. What is it really?
The product facts here don't cover what cordyceps is or where it comes from, only that this is a cordyceps mushroom extract. If you want to know more about the source or how it's grown, the brand or package label should have that information.
Can I take cordyceps with my blood thinner?
Not without checking first — cordyceps may increase bleeding risk when combined with blood thinners or antiplatelet drugs. This hasn't been reported in actual patients yet, but the research suggests it's possible. Talk with your doctor or pharmacist before adding it.
Does cordyceps help with sexual dysfunction?
The evidence isn't strong enough to say. We have insufficient reliable evidence to rate cordyceps for sexual dysfunction, which means we don't know if it works for that purpose yet.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Cordyceps Mushroom is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Cordyceps Mushroom label
Go deeper

The Full Monographs Behind Cordyceps Mushroom’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Cordyceps

Interacts with 249 drugs

Cordyceps is a fungus used in traditional Chinese medicine for energy, exercise performance, and lung and immune support. Human research is limited and mostly low quality, so its benefits ar...

Read the full Cordyceps monograph →
Sources

Sources & How We Checked

Cordyceps Mushroom's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 14 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Cordyceps 14 references
  1. Zhu JS, Halpern GM, Jones K. The scientific rediscovery of an ancient Chinese herbal medicine: Cordyceps sinensis: part I. J Altern Complement Med 1998;4:289-303.
  2. Zhu JS, Halpern GM, Jones K. The scientific rediscovery of a precious ancient Chinese herbal regimen: Cordyceps sinensis: part II. J Altern Complement Med 1998;4:429-57.
  3. Chen YJ, Shiao MS, Lee SS, Wang SY. Effect of Cordyceps sinensis on the proliferation and differentiation of human leukemic U937 cells. Life Sci 1997;60:2349-59. PubMed
  4. Zhao Y. [Inhibitory effects of alcoholic extract of Cordyceps sinensis on abdominal aortic thrombus formation in rabbits]. Chung Hua I Hsueh Tsa Chih (Taipei) 1991;71:612-5, 42.
  5. Chen GZ, Chen GL, Sun T, et al. Effects of Cordyceps sinensis on murine T lymphocyte subsets. Chin Med J (English) 1991;104:4-8.
  6. Zhu XY, Yu HY. [Immunosuppressive effect of cultured Cordyceps sinensis on cellular immune response]. Chung Hsi I Chieh Ho Tsa Chih 1990;10:485-7, 454.
  7. Hsu, C. C., Huang, Y. L., Tsai, S. J., Sheu, C. C., and Huang, B. M. In vivo and in vitro stimulatory effects of Cordyceps sinensis on testosterone production in mouse Leydig cells. Life Sci 9-5-2003;73(16):2127-2136. PubMed
  8. Ikumoto, T., Sasaki, S., Namba, H., Toyama, R., Moritoki, H., and Mouri, T. [Physiologically active compounds in the extracts from tochukaso and cultured mycelia of Cordyceps and Isaria]. Yakugaku Zasshi 1991;111(9):504-509. PubMed
  9. Wu, T. N., Yang, K. C., Wang, C. M., Lai, J. S., Ko, K. N., Chang, P. Y., and Liou, S. H. Lead poisoning caused by contaminated Cordyceps, a Chinese herbal medicine: two case reports. Sci.Total Environ. 4-5-1996;182(1-3):193-195. PubMed
  10. Hong T, Zhang M, Fan J. Cordyceps sinensis (a traditional Chinese medicine) for kidney transplant recipients (Review). Cochrane Database Syst Rev. 2015;(10):CD009698. doi: 10.1002/14651858.CD009698.pub2.
  11. Zhang HW, Lin ZX, Tung YS, Kwan TH, Mok CK, Leung C, Chan LS. Cordyceps sinensis (a traditional Chinese medicine) for treating chronic kidney disease (Review). Cochrane Database Syst Rev. 2014;(12):CD008353. doi: 10.1002/14651858.CD008353.pub2. PubMed
  12. Bee Yean O, Zoriah A. Efficacy of Cordyceps sinensis as an adjunctive treatment in hemodialysis patients: a systematic review and Meta-analysis. J Tradit Chin Med. 2019;39(1):1-14.
  13. Thurian D, Montani M, Stickel F. Drug-induced, mixed-type hepatitis following ingestion of Cordyceps sinensis. Int J Clin Pharmacol Ther 2022;60(2):115-120. PubMed
  14. Yu X, Mao Y, Shergis JL, et al. Effectiveness and safety of oral Cordyceps sinensis on stable COPD of GOLD stages 2-3: Systematic review and meta-analysis. Evid Based Complement Alternat Med. 2019;2019:4903671.

See these in context on the Cordyceps monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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