Major interaction on record — check this product against your medications before combining. Based on 5 of 6 ingredients. Check your meds →
Dietary supplement

Crave Stop Ingredients & Drug Interactions

by Redd Remedies

Crave Stop label
See full label image
Capsule Category: Botanical With Nutrients
Most serious interaction: Major
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Crave Stop against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Major

Crave Stop is a dietary supplement by Redd Remedies with 6 active ingredients. Its ingredients are commonly taken for blood sugar support, type 2 diabetes, sugar cravings.Based on those ingredients, 1,187 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Gymnema (Gymnema sylvestre) leaf extract, Banaba (Lagerstroemia speciosa) (Glucohelp) leaf extract, American Ginseng (Panax quinquefolium) root extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Crave Stop by Redd Remedies

Ask about any prescription or over-the-counter medication and we check it for interactions with Crave Stop by Redd Remedies — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Crave Stop by Redd Remedies

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 23, 2026

What’s inside

Partial disclosure
Ingredient Transparency · database check
Partial

Most active ingredients list an amount, but at least one is hidden in a blend or missing.

Why this rating?
  • The label discloses an exact amount for 3 of its 6 active ingredients.

Crave Stop contains six active ingredients. Gymnema (an Ayurvedic plant extract), vanadium (a trace mineral), chromium (another trace mineral), American ginseng root extract, and banaba leaf extract are the five we have data on; we could not check the Healthy Appetite Blend proprietary blend.

The product also contains inactive ingredients—vegetarian capsule, microcrystalline cellulose (a binder), magnesium stearate, and silicon dioxide—which are standard tablet and capsule fillers.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: blood sugar support and sugar cravings.
  • We looked for evidence on: Diabetes, Impaired glucose tolerance (prediabetes), Hypoglycemia, Metabolic syndrome, Obesity, Polycystic ovary syndrome (PCOS) — and 4 related terms.
  • The strongest evidence on file: Vanadium is rated "Likely Effective" for Vanadium deficiency (Natural Medicines).
  • Also on file: Chromium is rated "Likely Effective" for Chromium deficiency.
  • Also on file: Chromium is rated "Possibly Effective" for Diabetes.

The evidence for this product's purposes isn't yet established in our data. Gymnema shows insufficient reliable evidence for diabetes, obesity, or prediabetes; chromium is possibly effective for diabetes but possibly ineffective for prediabetes; American ginseng is possibly effective for upper respiratory tract infections; and banaba has insufficient evidence for diabetes, prediabetes, or metabolic syndrome.

Vanadium is likely effective for vanadium deficiency but has insufficient evidence for diabetes or other uses.

The evidence, ingredient by ingredient Gymnema Vanadium Chromium American Ginseng Banaba

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 5 of the 5 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 5 of 5.
  • General safety write-ups exist for 5 of 5.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Gymnema is generally well tolerated short-term, but a rare case of drug-induced liver inflammation (hepatitis) was reported in someone who drank gymnema tea three times daily for 10 days; liver function normalized after 6 months. Vanadium at supplement doses can cause stomach upset, diarrhea, and nausea above the safe upper limit of 1.8 mg daily; rare cases of kidney damage have been reported at high doses over time.

Chromium is usually well tolerated at typical doses, though gastrointestinal irritation, headaches, and mood changes occur, and rare serious cases of kidney and liver damage have been reported. American ginseng is generally well tolerated short-term but may cause headaches; long-term safety isn't well studied.

Banaba appears well tolerated in short studies, though dizziness, headaches, tremor, and weakness were reported in one combination product (it's unclear which ingredient caused them). The product should be avoided during pregnancy and breastfeeding: gymnema, vanadium (supplement doses), chromium (extra supplement doses), American ginseng, and banaba all lack enough safety data to recommend their use.

Side effects, ingredient by ingredient Gymnema Vanadium Chromium American Ginseng Banaba

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 5 of the 5 matched ingredients can interact with medications — Vanadium, Gymnema, Chromium, American Ginseng, Banaba.
  • The most serious interaction on file is rated Major.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; immunosuppressants / transplant drugs; diabetes medications.
  • For scale: 1,188 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking Crave Stop, check with your doctor or pharmacist if you take warfarin or other blood thinners—American ginseng may reduce their effectiveness (Major severity). Also double-check if you're on diabetes medications (including insulin), blood pressure medications, thyroid medication (levothyroxine), immunosuppressant drugs, or MAOIs (older antidepressants)—all documented as moderate concerns with ingredients in this product.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glancePartially disclosed formula with clinical evidence supporting its stated purpose. Major medication interactions have been identified, and safety information is well characterized.

Crave Stop combines five botanical and mineral ingredients with documented interactions, the most serious being American ginseng with blood thinners like warfarin. If you take any blood thinners, diabetes medications, thyroid medication, blood pressure medication, immune-suppressing drugs, or an older antidepressant (MAOI), talk with your doctor or pharmacist before using this product.

Don't take it during pregnancy or breastfeeding. Use the medication interaction checker on this page to verify your specific prescriptions.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 5 of 6 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jan 25, 2016.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Crave Stop, straight from the product label.

Brand Redd Remedies
Barcode (UPC) 855735001255
Net contents 60 Vegetarian Capsule(s)
Market status On market
Date entered into DSLD Jan 25, 2016
DSLD ID 56022
Product type Botanical With Nutrients
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegetarian, Adult (18 - 50 Years), Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Crave Stop by Redd Remedies, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Vegetarian Capsule(s)
Maximum serving Sizes:
2 Vegetarian Capsule(s)
Servings per container
30
UPC/BARCODE
855735001255
IngredientAmount% DV
Gymnema (Gymnema sylvestre) leaf extract0 NP--
Vanadium100 mcg--
Chromium200 mcg167%
Healthy Appetite Blend380 mg--
American Ginseng (Panax quinquefolium) root extract0 NP--
Banaba (Lagerstroemia speciosa) (Glucohelp) leaf extract0 NP--

Other ingredients: Vegetarian Capsule, Microcrystalline Cellulose, Magnesium Stearate, Silicon Dioxide

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Brand IP Statement(s)

Putting Health In Order

Chromium 454 is a registered trademark of VDF Futureceuticals, Inc., used under license.

Glucohelp is a registered trademark of OptiPure brand.

Crave Stop is designed to help manage sugar and food cravings and promote a healthy caloric intake.*

General Statements

{Capsule} Actual Size

{Capsule} Actual Size

Helps manage sugar cravings Supports a healthy appetite Supports healthy weight management

FDA Statement of Identity

Dietary Supplement

Formulation

Vegetarian

Contains no: sugar, sodium, corn, dairy products, artificial flavoring or coloring, preservatives or animal ingredients.

Seals/Symbols

Quality & Pure Guaranteed. Laboratory Tested

Suggested/Recommended/Usage/Directions

Suggested Use: 2 capsules daily. Best taken in divided dose.

Precautions

Warning: Insulin Dependent Diabetics should consult with a healthcare practitioner prior to use.

If pregnant, nursing, or taking prescription drugs, discuss all products used with a healthcare practitioner.

FDA Disclaimer Statement

* This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Crave Stop by Redd Remedies label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Crave Stop label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Crave Stop by Redd Remedies

These are the 6 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 Vegetarian Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Gymnema (Gymnema sylvestre) leaf extract

Interacts with
851 drugs
0 NP per serving

Gymnema is an Ayurvedic herb best known for possibly helping lower blood sugar and reducing the taste of sweetness on the tongue. Some early human stu...

Gymnema (Gymnema sylvestre) leaf extract monograph & interactions

Vanadium

Interacts with
208 drugs
100 mcg per serving Form: Vanadium Amino Acid Chelate

Vanadium is a trace mineral found in tiny amounts in food, and people get plenty from a normal diet. Supplement claims for diabetes, weight, and athle...

Vanadium monograph & interactions

Chromium

Interacts with
178 drugs
200 mcg per serving Form: Chromium 454

Chromium is an essential trace mineral involved in how the body handles sugar and fat. Some studies suggest it may modestly help blood sugar control i...

Chromium monograph & interactions

Healthy Appetite Blend

380 mg per serving

American Ginseng (Panax quinquefolium) root extract

Interacts with
217 drugs
0 NP per serving

American ginseng is an herbal root used as an 'adaptogen' to support energy, stress, immune function, and blood sugar. Some uses—such as reducing the...

American Ginseng (Panax quinquefolium) root extract monograph & interactions

Banaba (Lagerstroemia speciosa) (Glucohelp) leaf extract

Interacts with
299 drugs
0 NP per serving

Banaba is a leaf extract most often used to help support healthy blood sugar, and small early studies suggest its active compound corosolic acid may m...

Banaba (Lagerstroemia speciosa) (Glucohelp) leaf extract monograph & interactions

Other (inactive) ingredients: Vegetarian Capsule, Microcrystalline Cellulose, Magnesium Stearate, Silicon Dioxide. These complete the product’s ingredient list but are not active constituents.

Interaction report

Crave Stop by Redd Remedies Drug Interactions

Want to check YOUR meds against Crave Stop?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
1,187Drugs
2 Major 739 Moderate 446 Minor

Ingredients driving the most interactions

Gymnema (Gymnema sylvestre) leaf extract 851
Banaba (Lagerstroemia speciosa) (Glucohelp) leaf extract 299
American Ginseng (Panax quinquefolium) root extract 217
Vanadium 208
Chromium 178

Individual Drug Interactions

The ingredients in Crave Stop interact with 1,187 drugs. Click any drug to see the details.

5 of the 6 ingredients in Crave Stop interact with drugs. Each result below shows which ingredient is responsible. Gymnema (Gymnema sylvestre) leaf extract Banaba (Lagerstroemia speciosa) (Glucohelp) leaf extract American Ginseng (Panax quinquefolium) root extract Vanadium Chromium

Each ingredient & the kinds of drugs it affects

For each ingredient in Crave Stop with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Gymnema (Gymnema sylvestre) leaf extract6 drug types · 851 drugs

Antidiabetes Drugs

Theoretically, taking gymnema with antidiabetes drugs might increase the risk of hypoglycemia.
Gymnema reduces blood glucose levels in some human and animal research. In human studies, it has been shown to enhance the blood glucose lowering effects of hypoglycemic drugs. However, other research in adults with prediabetes or metabolic syndrome suggests that gymnema does not reduce fasting levels of blood glucose. Until more is known, monitor blood glucose levels closely.

Likelihood Probable Evidence B
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, gymnema might increase levels of drugs metabolized by CYP1A2.
Animal and in vitro research shows that gymnema can inhibit the CYP1A2 enzyme. In one animal study, oral administration of gymnema for 7 days increased the plasma concentrations of phenacetin, a CYP1A2 substrate, by about 1.4-fold and reduced the clearance of phenacetin by about 29%.

Likelihood Possible Evidence D
Cytochrome P450 2C9 (Cyp2C9) Substrates

Theoretically, gymnema might increase or decrease levels of drugs metabolized by CYP2C9.
Animal research shows that gymnema can induce the CYP2C9 enzyme. In one animal study, gymnema caused a 2.4-fold increase in the clearance of tolbutamide, a CYP2C9 substrate, in rats. In vitro research also shows that gymnema can inhibit CYP2C9.

Likelihood Possible Evidence D
Phenacetin

Theoretically, taking gymnema with phenacetin might increase the levels of phenacetin.
Animal research shows that gymnema, administered orally for 7 days, decreases the clearance of phenacetin in a dose-dependent manner by about 21% to 29% and increases plasma levels about 1.3- to 1.4-fold when compared to control.

Likelihood Possible Evidence D
Tolbutamide (Orinase)

Theoretically, taking gymnema with tolbutamide might the decrease levels of tolbutamide.
Animal research shows that gymnema, administered orally for 7 days, increases the clearance of tolbutamide by 2.4-fold when compared to control.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, gymnema might increase levels of drugs metabolized by CYP3A4.
One in vitro study using rat liver microsomes shows that gymnema can modestly inhibit the CYP3A4 enzyme. However, other in vitro research using human liver microsomes shows that gymnema does not affect CYP3A4 activity. Animal research also shows that gymnema does not alter the function of CYP3A4. In one study in rats, oral administration of gymnema for 7 days did not alter the clearance of amlodipine, a CYP3A4 substrate.

Likelihood Unlikely Evidence D
Gymnema (Gymnema sylvestre) leaf extract full monograph & interactions

Banaba (Lagerstroemia speciosa) (Glucohelp) leaf extract3 drug types · 299 drugs

Antidiabetes Drugs

Theoretically, concomitant use of banaba and hypoglycemic drugs might have additive effects.
Human and animal research suggests that banaba can lower blood glucose levels.

Likelihood Probable Evidence B
Antihypertensive Drugs

Theoretically, concomitant use of banaba and antihypertensive drugs might cause additive effects.
Human and animal research suggests that banaba can lower blood pressure.

Likelihood Probable Evidence B
Organic Anion-Transporting Polypeptide Substrates (Oatp)

Theoretically, concomitant use of banaba with substrates of OATP might reduce the bioavailability of the OATP substrate.
In vitro research shows that banaba inhibits OATP, particularly OATP2B1. OATPs are expressed in the small intestine and liver and are responsible for the absorption of drugs and other compounds.

Likelihood Possible Evidence D
Banaba (Lagerstroemia speciosa) (Glucohelp) leaf extract full monograph & interactions

American Ginseng (Panax quinquefolium) root extract4 drug types · 217 drugs

Warfarin (Coumadin)

American ginseng seems to decrease the effectiveness of warfarin therapy.
Healthy patients receiving warfarin 5 mg daily, who also take American ginseng 1 gram twice daily, seem to have a significantly reduced international normalized ratio (INR).

Likelihood Likely Evidence B
Antidiabetes Drugs

Theoretically, taking American ginseng with antidiabetes drugs might increase the risk of hypoglycemia.
American ginseng seems to lower postprandial blood glucose. Theoretically, concomitant use with antidiabetes drugs might enhance blood glucose lowering effects and possibly cause hypoglycemia.

Likelihood Probable Evidence B
Immunosuppressants

Theoretically, American ginseng use might interfere with immunosuppressive therapy.
American ginseng seems to stimulate immune function. Theoretically, American ginseng might decrease the effectiveness of immunosuppressant drugs.

Likelihood Possible Evidence D
Monoamine Oxidase Inhibitors (Maois)

Theoretically, American ginseng can interfere with MAOI therapy.
There is one case report of insomnia, headache, and tremors when an unspecified ginseng product was used with phenelzine (Nardil), an MAOI. There is also one case report of hypomania when an unspecified ginseng product was used with phenelzine. Theoretically, American ginseng may interfere with MAOI therapy.

Likelihood Possible Evidence D
American Ginseng (Panax quinquefolium) root extract full monograph & interactions

Vanadium2 drug types · 208 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, vanadium might increase the risk of bleeding when taken with anticoagulant/antiplatelet drugs.
In vitro research shows that the sodium orthovanadate form of vanadium prolongs clotting time, likely through inhibition of thrombin and factor Xa.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, vanadium might increase the risk of hypoglycemia when taken with antidiabetes drugs.
A few very small clinical studies in patients with type 2 diabetes show that the vanadyl sulfate form of vanadium increases insulin sensitivity and might lower blood glucose levels.

Likelihood Probable Evidence B
Vanadium full monograph & interactions

Chromium5 drug types · 178 drugs

Antidiabetes Drugs

Theoretically, chromium may have additive effects with antidiabetic agents and increase the risk of hypoglycemia.
Some research shows that taking chromium might lower blood glucose levels, especially in patients with poorly controlled type 2 diabetes.

Likelihood Possible Evidence A
Insulin

Theoretically, concomitant use of chromium and insulin might increase the risk of hypoglycemia.
In clinical research, chromium has been shown to increase insulin sensitivity,

Likelihood Possible Evidence B
Levothyroxine (Synthroid, Others)

Chromium might bind levothyroxine in the intestinal tract and decrease levothyroxine absorption.
Clinical research in healthy volunteers shows that taking chromium picolinate 1000 mcg with levothyroxine 1 mg decreases serum levels of levothyroxine by 17% when compared to taking levothyroxine alone. Advise patients to take levothyroxine at least 30 minutes before or 3-4 hours after taking chromium.

Likelihood Probable Evidence B
Aspirin

Theoretically, aspirin might increase chromium absorption.
Animal research suggests that aspirin may increase chromium absorption and chromium levels in the blood.

Likelihood Possible Evidence D
Nonsteroidal Anti-Inflammatory Drugs (Nsaids)

NSAIDs might increase chromium levels in the body.
Drugs that are prostaglandin inhibitors, such as NSAIDs, seem to increase chromium absorption and retention.

Likelihood Possible Evidence D
Chromium full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Crave Stop, from the product label.

Redd Remedies

See all Redd Remedies products
Name
Redd Remedies
City
Bradley
State
IL
ZipCode
60915
Phone Number
888-453-5058
Web Address
www.reddremedies.com
Pharmacist Counseling Corner

Crave Stop by Redd Remedies: Common Questions

Does Crave Stop by Redd Remedies interact with any medications?
Yes. Based on its ingredients, Crave Stop has a known interaction with 1,187 medications, including 2 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Crave Stop contains 6 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm on metformin or another diabetes drug?
Not without checking first with your doctor. Gymnema, vanadium, chromium, American ginseng, and banaba all lower blood sugar, so combining them with diabetes medications increases your risk of low blood sugar (hypoglycemia). Talk with your doctor or pharmacist before starting.
Is it safe to take if I'm pregnant or breastfeeding?
No. The safety data for all five active ingredients is either lacking or advises against use during pregnancy and breastfeeding. Avoid this product and talk with your doctor or pharmacist before taking any supplement during pregnancy or nursing.
I take warfarin. Can I use Crave Stop?
No. American ginseng in this product appears to reduce warfarin's effectiveness and lower your blood clotting ability, which is serious. Talk with your doctor or pharmacist before using any supplement while on warfarin.
I take levothyroxine for my thyroid. Is this product okay?
Probably not without checking first. Chromium in this product may bind to levothyroxine in your gut and reduce how much gets absorbed, making your thyroid medication less effective. Talk with your doctor or pharmacist before starting.
What does each ingredient actually do?
The evidence isn't clear yet for most of them in our data. Gymnema, chromium, and banaba are studied for blood sugar control; American ginseng for cold and flu symptoms; vanadium for vanadium deficiency; and the Healthy Appetite Blend's purposes we cannot determine from the data we hold.
What are the most common side effects?
Gymnema, vanadium, chromium, and banaba can all cause stomach upset, nausea, diarrhea, dizziness, headaches, or tremor in some people. American ginseng may cause headache. A very rare case of liver inflammation was reported with gymnema, and high-dose vanadium has rarely caused kidney damage.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Crave Stop label
Go deeper

The Full Monographs Behind Crave Stop’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Gymnema

Interacts with 851 drugs

Gymnema is an Ayurvedic herb best known for possibly helping lower blood sugar and reducing the taste of sweetness on the tongue. Some early human studies are encouraging for blood sugar sup...

Read the full Gymnema monograph → Herb & supplement monograph

Vanadium

Interacts with 208 drugs

Vanadium is a trace mineral found in tiny amounts in food, and people get plenty from a normal diet. Supplement claims for diabetes, weight, and athletic performance are not well proven, and...

Read the full Vanadium monograph → Herb & supplement monograph

Chromium

Interacts with 178 drugs

Chromium is an essential trace mineral involved in how the body handles sugar and fat. Some studies suggest it may modestly help blood sugar control in certain people with type 2 diabetes, b...

Read the full Chromium monograph → Herb & supplement monograph

American Ginseng

Interacts with 217 drugs

American ginseng is an herbal root used as an 'adaptogen' to support energy, stress, immune function, and blood sugar. Some uses—such as reducing the chance or length of colds and modestly l...

Read the full American Ginseng monograph → Herb & supplement monograph

Banaba

Interacts with 299 drugs

Banaba is a leaf extract most often used to help support healthy blood sugar, and small early studies suggest its active compound corosolic acid may modestly lower glucose. The overall evide...

Read the full Banaba monograph →
Sources

Sources & How We Checked

Crave Stop's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 99 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Gymnema 12 references
  1. Shanmugasundaram ER, Rajeswari G, Baskaran K, et al. Use of Gymnema sylvestre leaf extract in the control of blood glucose in insulin-dependent diabetes mellitus. J Ethnopharmacol 1990;30:281-94. PubMed
  2. Baskaran K, Kizar Ahamath B, Radha Shanmugasundaram K, Shanmugasundaram ER. Antidiabetic effect of leaf extract from Gymnema sylvestre in non-insulin-dependent diabetes mellitus patients. J Ethnopharmacol 1990;30:295-300.
  3. Kamble B, Gupta A, Moothedath I, Khatal L, Janrao S, Jadhav A, et al. Effects of Gymnema sylvestre extract on the pharmacokinetics and pharmacodynamics of glimepiride in streptozotocin induced diabetic rats. Chem Biol Interact. 2016;245:30-8. PubMed
  4. Tiwari P, Mishra BN, Sangwan NS. Phytochemical and pharmacological properties of Gymnema sylvestre: an important medicinal plant. Biomed Res Int. 2014; 2014:830285.
  5. Fabio GD, Romanucci V, De Marco A, Zarrelli A. Triterpenoids from Gymnema sylvestre and their pharmacological activities. Molecules. 2014;19(8):10956-81. PubMed
  6. Shiyovich A, Sztarkier I, Nesher L. Toxic hepatitis induced by Gymnema sylvestre, a natural remedy for type 2 diabetes mellitus. Am J Med Sci. 2010;340(6):514-7. PubMed
  7. Zuniga LY, Gonzalez-Ortiz M, Martinez-Abundis E. Effect of gymnema sylvestre administration on metabolic syndrome, insulin sensitivity, and insulin secretion. J Med Food. 2017 Aug;20(8):750-54.
  8. Rammohan B, Samit K, Chinmoy D, et al. Human cytochrome P450 enzyme modulation by gymnema sylvestre: a predictive safety evaluation by LC-MS/MS. Pharmacogn Mag. 2016 Jul;12(Suppl 4):S389-S394.
  9. Vaghela M, Sahu N, Kharkar P, Pandita N. In vivo pharmacokinetic interaction by ethanolic extract of gymnema sylvestre with CYP2C9 (tolbutamide), CYP3A4 (amlodipine) and CYP1A2 (phenacetin) in rats. Chem Biol Interact. 2017 Dec 25;278:141-151. PubMed
  10. Vaghela M, Iyer K, Pandita N. In vitro inhibitory effect of gymnema sylvestre extracts and total gymnemic acids fraction on select cytochrome P450 activities in rat liver microsomes. Eur J Drug Metab Pharmacokinet. 2017 Oct 10. PubMed
  11. Gaytán Martínez LA, Sánchez-Ruiz LA, Zuñiga LY, González-Ortiz M, Martínez-Abundis E. Effect of Gymnema sylvestre administration on glycemic control, insulin secretion, and insulin sensitivity in patients with impaired glucose tolerance. J Med Food. 2021;
  12. Philips CA, Theruvath AH, Ravindran R. Toxic hepatitis-associated aplastic anaemia after dual homeopathic remedies and Gymnema sylvestre use. BMJ Case Rep 2022;15(3):e247867. PubMed

See these in context on the Gymnema monograph →

Vanadium 15 references
  1. Harland BF, Harden-Williams BA. Is vanadium of human nutritional importance yet? J Am Diet Assoc 1994;94:891-4. PubMed
  2. Sitprija V, Tungsanga K, Tosukhowong P, et al. Metabolic problems in northeastern Thailand: possible role of vanadium. Mineral Electrolyte Metab 1998;19:51-6.
  3. Funakoshi T, Shimada H, Kojima S, et al. Anticoagulant action of vanadate. Chem Pharmaceut Bull 1992;40:174-6. PubMed
  4. Halberstam M, Cohen N, Shlimovich P, et al. Oral vanadyl sulfate improves insulin sensitivity in NIDDM but not in obese nondiabetic subjects. Diabetes 1996;45:659-66. PubMed
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Chromium 53 references
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American Ginseng 12 references
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Banaba 7 references
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