Culver's Root Ingredients & Drug Interactions
by Herbal Terra
What is this page for?
First and foremost: checking Culver's Root against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Culver's Root is a dietary supplement by Herbal Terra with 1 active ingredient. Its ingredients are commonly taken for constipation, liver and gallbladder complaints, digestive upset.Based on those ingredients, 78 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are certified organic Culver's Root (Veronicastrum virginicum) dried root liquid extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Culver's Root by Herbal Terra
Ask about any prescription or over-the-counter medication and we check it for interactions with Culver's Root by Herbal Terra — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Culver's Root by Herbal Terra
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
Culver's Root contains one active ingredient: certified organic Culver's Root (Veronicastrum virginicum) dried root liquid extract. The liquid is prepared with menstruum, which is the solvent used to extract the plant's compounds.
This is a straightforward single-ingredient product.
Does it work?
Couldn't assess
No effectiveness ratings are listed in our data for Culver's Root. We don't have established evidence on file for what this product is intended to do, so we can't tell you whether it works for its claimed purpose.
How safe is it?
Well-documented data
Modern safety data for Culver's Root are limited. The fresh root can cause significant digestive irritation, and the product may trigger abdominal pain or cramps, changes in stool color or odor, drowsiness, headache, nausea, and vomiting.
Hepatotoxicity (liver damage) has been reported after ingestion of large amounts. The safety data advises against use during pregnancy because of its strong laxative effect and lack of safety information.
There isn't enough data on file to know whether it's safe while breastfeeding—talk with your doctor or pharmacist about that if it applies to you.
Meds to double-check
Moderate interaction found
Before taking Culver's Root, check whether you use warfarin (Coumadin) or other blood thinners, diuretics (water pills), or digoxin (Lanoxin). These medications have documented Moderate interactions with this product.
Use the medication checker on this page to confirm your exact prescriptions.
The bottom line
Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
Culver's Root is a single-ingredient herbal extract with documented interactions in patients on blood thinners, diuretics, or heart medications. If you take any of those drug types, or any prescription at all, check your medications with the tool below before you start.
Talk to your pharmacist about whether this product is right for you.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Sep 25, 2020.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Culver's Root, straight from the product label.
| Brand | Herbal Terra |
|---|---|
| Barcode (UPC) | 7429523587547 |
| Net contents | 4 Fluid Ounce(s); 120 mL |
| Market status | On market |
| Date entered into DSLD | Sep 25, 2020 |
| DSLD ID | 235358 |
| Product type | Botanical |
| Supplement form | Liquid |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Organic, Gluten Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Culver's Root by Herbal Terra, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| certified organic Culver's Root (Veronicastrum virginicum) dried root liquid extract | 970 mg | -- |
Other ingredients: Menstruum
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation
Origin of plant material: USA.
Manufactured in the USA in an FDA registered facility
Alcohol free
Dried herb/menstruum ratio: 1:3 Expertly extracted Laboratory tested 330 mg/1 mL Premium product Alcohol-free liquid herbal extract
Non GMO
No artificial ingredients, GMO, gluten, color additives, fillers, preservatives or binders. Natural Gluten Free
Suggested/Recommended/Usage/Directions
Direction Shake well before use. Adults take up to 30 drops (1 mL, one full squeeze of the dropper bulb) in 3-4 fl. oz of juice or water up to 4 times a day. We recommend to seek expert medical advice before taking this or any other herbal supplements.
FDA Disclaimer Statement
Notice This product has not been evaluated by the FDA and is not intended to diagnose, treat, cure, or prevent any disease.
Precautions
Caution May have contraindications.
Do not use if you are allergic to any ingredients.
Consult a physician before using during pregnancy, if nursing, or if you are on any medications.
Keep out of the reach of children.
Storage
Store in a cool, dry, dark place.
Formula
Veronicastrum virginicum
FDA Statement of Identity
Herbal Supplement
Seals/Symbols
Made in USA Made in an FDA registered facility Natural Gluten Free
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Culver's Root by Herbal Terra label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Culver's Root by Herbal Terra
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 mL Dosage formLiquid Servings per container120 Amounts shown are per serving.
Certified organic Culver's Root (Veronicastrum virginicum) dried root liquid extract
Interacts with78 drugs
Black Root is a traditional North American herb that was historically used as a strong laxative and to support digestion and liver function. There is...
Certified organic Culver's Root (Veronicastrum virginicum) dried root liquid extract monograph & interactionsOther (inactive) ingredients: Menstruum. These complete the product’s ingredient list but are not active constituents.
Culver's Root by Herbal Terra Drug Interactions
HelloPharmacist Interaction Report
Culver's Root by Herbal Terra is a single-ingredient liquid extract that does interact with several important medications.
The most serious concern is with blood thinners like warfarin (Coumadin). Culver's Root has strong laxative effects, and diarrhea from overuse can increase how much warfarin your body absorbs, raising your bleeding risk.
If you take warfarin, avoid taking large amounts of this product.
Read the full breakdown — every affected drug type, severity by severity
You'll also want to be cautious if you take diuretics (water pills) or digoxin (Lanoxin), a heart medication. Diuretics can already lower your potassium levels, and Culver's Root may add to that effect—you might need extra potassium supplementation.
Digoxin is a narrow-margin drug where even small changes in absorption matter; Culver's Root can chemically bind to it in your digestive tract and reduce how well it works.
Altogether, these interactions span 78 individual medications. Use the medication checker on this page to look up your exact drugs before you start.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Culver's Root?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Culver's Root interact with 78 drugs. Click any drug to see the details.
1 of the 1 ingredient in Culver's Root interact with drugs. Each result below shows which ingredient is responsible. certified organic Culver's Root (Veronicastrum virginicum) dried root liquid extract
Acetaminophen, Caffeine, PyrilamineMidol Max Strength Menstrual
How Acetaminophen, Caffeine, Pyrilamine interacts with Culver's Root — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Culver's Root (veronicastrum Virginicum) Dried Root Liquid ExtractDiuretic Drugs Moderate
Interaction Summary
Overuse of black root might compound diuretic-induced potassium loss.There is some concern that people taking black root along with potassium depleting diuretics might have an increased risk for hypokalemia.
Read the full Certified Organic Culver's Root (veronicastrum Virginicum) Dried Root Liquid Extract + Acetaminophen, Caffeine, Pyrilamine interactionAcetaminophen, Pamabrom, PyrilamineMidol Max Strength PMS, Pamprin, Pamprin ES
How Acetaminophen, Pamabrom, Pyrilamine interacts with Culver's Root — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Culver's Root (veronicastrum Virginicum) Dried Root Liquid ExtractDiuretic Drugs Moderate
Interaction Summary
Overuse of black root might compound diuretic-induced potassium loss.There is some concern that people taking black root along with potassium depleting diuretics might have an increased risk for hypokalemia.
Read the full Certified Organic Culver's Root (veronicastrum Virginicum) Dried Root Liquid Extract + Acetaminophen, Pamabrom, Pyrilamine interactionAcetazolamideAk-Zol, Diamox
How Acetazolamide interacts with Culver's Root — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Culver's Root (veronicastrum Virginicum) Dried Root Liquid ExtractDiuretic Drugs Moderate
Interaction Summary
Overuse of black root might compound diuretic-induced potassium loss.There is some concern that people taking black root along with potassium depleting diuretics might have an increased risk for hypokalemia.
Read the full Certified Organic Culver's Root (veronicastrum Virginicum) Dried Root Liquid Extract + Acetazolamide interactionAmiloride, HydrochlorothiazideAmil-Co, Amilzide, Moduret 25, Moduretic
How Amiloride, Hydrochlorothiazide interacts with Culver's Root — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Culver's Root (veronicastrum Virginicum) Dried Root Liquid ExtractDiuretic Drugs Moderate
Interaction Summary
Overuse of black root might compound diuretic-induced potassium loss.There is some concern that people taking black root along with potassium depleting diuretics might have an increased risk for hypokalemia.
Read the full Certified Organic Culver's Root (veronicastrum Virginicum) Dried Root Liquid Extract + Amiloride, Hydrochlorothiazide interactionAmmonium ChlorideAmmonium Chloride
How Ammonium Chloride interacts with Culver's Root — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Culver's Root (veronicastrum Virginicum) Dried Root Liquid ExtractDiuretic Drugs Moderate
Interaction Summary
Overuse of black root might compound diuretic-induced potassium loss.There is some concern that people taking black root along with potassium depleting diuretics might have an increased risk for hypokalemia.
Read the full Certified Organic Culver's Root (veronicastrum Virginicum) Dried Root Liquid Extract + Ammonium Chloride interactionAtenolol, ChlortalidoneAtenixCo, Tenoret 50, Totaretic
How Atenolol, Chlortalidone interacts with Culver's Root — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Culver's Root (veronicastrum Virginicum) Dried Root Liquid ExtractDiuretic Drugs Moderate
Interaction Summary
Overuse of black root might compound diuretic-induced potassium loss.There is some concern that people taking black root along with potassium depleting diuretics might have an increased risk for hypokalemia.
Read the full Certified Organic Culver's Root (veronicastrum Virginicum) Dried Root Liquid Extract + Atenolol, Chlortalidone interactionAtenolol, ChlorthalidoneTenoretic
How Atenolol, Chlorthalidone interacts with Culver's Root — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Culver's Root (veronicastrum Virginicum) Dried Root Liquid ExtractDiuretic Drugs Moderate
Interaction Summary
Overuse of black root might compound diuretic-induced potassium loss.There is some concern that people taking black root along with potassium depleting diuretics might have an increased risk for hypokalemia.
Read the full Certified Organic Culver's Root (veronicastrum Virginicum) Dried Root Liquid Extract + Atenolol, Chlorthalidone interactionAzilsartan, ChlorthalidoneEdarbyclor
How Azilsartan, Chlorthalidone interacts with Culver's Root — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Culver's Root (veronicastrum Virginicum) Dried Root Liquid ExtractDiuretic Drugs Moderate
Interaction Summary
Overuse of black root might compound diuretic-induced potassium loss.There is some concern that people taking black root along with potassium depleting diuretics might have an increased risk for hypokalemia.
Read the full Certified Organic Culver's Root (veronicastrum Virginicum) Dried Root Liquid Extract + Azilsartan, Chlorthalidone interactionBenazepril, HydrochlorothiazideLotensin HCT
How Benazepril, Hydrochlorothiazide interacts with Culver's Root — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Culver's Root (veronicastrum Virginicum) Dried Root Liquid ExtractDiuretic Drugs Moderate
Interaction Summary
Overuse of black root might compound diuretic-induced potassium loss.There is some concern that people taking black root along with potassium depleting diuretics might have an increased risk for hypokalemia.
Read the full Certified Organic Culver's Root (veronicastrum Virginicum) Dried Root Liquid Extract + Benazepril, Hydrochlorothiazide interactionBendroflumethiazideAprinox, Naturetin, Neo-NaClex
How Bendroflumethiazide interacts with Culver's Root — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Culver's Root (veronicastrum Virginicum) Dried Root Liquid ExtractDiuretic Drugs Moderate
Interaction Summary
Overuse of black root might compound diuretic-induced potassium loss.There is some concern that people taking black root along with potassium depleting diuretics might have an increased risk for hypokalemia.
Read the full Certified Organic Culver's Root (veronicastrum Virginicum) Dried Root Liquid Extract + Bendroflumethiazide interactionBendroflumethiazide, NadololCorzide
How Bendroflumethiazide, Nadolol interacts with Culver's Root — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Culver's Root (veronicastrum Virginicum) Dried Root Liquid ExtractDiuretic Drugs Moderate
Interaction Summary
Overuse of black root might compound diuretic-induced potassium loss.There is some concern that people taking black root along with potassium depleting diuretics might have an increased risk for hypokalemia.
Read the full Certified Organic Culver's Root (veronicastrum Virginicum) Dried Root Liquid Extract + Bendroflumethiazide, Nadolol interactionBendroflumethiazide, PotassiumCentyl K, Neo-NaClex-K
How Bendroflumethiazide, Potassium interacts with Culver's Root — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Culver's Root (veronicastrum Virginicum) Dried Root Liquid ExtractDiuretic Drugs Moderate
Interaction Summary
Overuse of black root might compound diuretic-induced potassium loss.There is some concern that people taking black root along with potassium depleting diuretics might have an increased risk for hypokalemia.
Read the full Certified Organic Culver's Root (veronicastrum Virginicum) Dried Root Liquid Extract + Bendroflumethiazide, Potassium interactionBendroflumethiazide, Rauwolfia SerpentinaRauzide
How Bendroflumethiazide, Rauwolfia Serpentina interacts with Culver's Root — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Culver's Root (veronicastrum Virginicum) Dried Root Liquid ExtractDiuretic Drugs Moderate
Interaction Summary
Overuse of black root might compound diuretic-induced potassium loss.There is some concern that people taking black root along with potassium depleting diuretics might have an increased risk for hypokalemia.
Read the full Certified Organic Culver's Root (veronicastrum Virginicum) Dried Root Liquid Extract + Bendroflumethiazide, Rauwolfia Serpentina interactionBenzthiazideExna
How Benzthiazide interacts with Culver's Root — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Culver's Root (veronicastrum Virginicum) Dried Root Liquid ExtractDiuretic Drugs Moderate
Interaction Summary
Overuse of black root might compound diuretic-induced potassium loss.There is some concern that people taking black root along with potassium depleting diuretics might have an increased risk for hypokalemia.
Read the full Certified Organic Culver's Root (veronicastrum Virginicum) Dried Root Liquid Extract + Benzthiazide interactionBisoprolol, HydrochlorothiazideZiac
How Bisoprolol, Hydrochlorothiazide interacts with Culver's Root — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Culver's Root (veronicastrum Virginicum) Dried Root Liquid ExtractDiuretic Drugs Moderate
Interaction Summary
Overuse of black root might compound diuretic-induced potassium loss.There is some concern that people taking black root along with potassium depleting diuretics might have an increased risk for hypokalemia.
Read the full Certified Organic Culver's Root (veronicastrum Virginicum) Dried Root Liquid Extract + Bisoprolol, Hydrochlorothiazide interactionBumetanideBurinex
How Bumetanide interacts with Culver's Root — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Culver's Root (veronicastrum Virginicum) Dried Root Liquid ExtractDiuretic Drugs Moderate
Interaction Summary
Overuse of black root might compound diuretic-induced potassium loss.There is some concern that people taking black root along with potassium depleting diuretics might have an increased risk for hypokalemia.
Read the full Certified Organic Culver's Root (veronicastrum Virginicum) Dried Root Liquid Extract + Bumetanide interactionBumetanide, PotassiumBurinex K
How Bumetanide, Potassium interacts with Culver's Root — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Culver's Root (veronicastrum Virginicum) Dried Root Liquid ExtractDiuretic Drugs Moderate
Interaction Summary
Overuse of black root might compound diuretic-induced potassium loss.There is some concern that people taking black root along with potassium depleting diuretics might have an increased risk for hypokalemia.
Read the full Certified Organic Culver's Root (veronicastrum Virginicum) Dried Root Liquid Extract + Bumetanide, Potassium interactionCaffeine, Potassium Salicylate, SalicylamideTrim-Elim
How Caffeine, Potassium Salicylate, Salicylamide interacts with Culver's Root — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Culver's Root (veronicastrum Virginicum) Dried Root Liquid ExtractDiuretic Drugs Moderate
Interaction Summary
Overuse of black root might compound diuretic-induced potassium loss.There is some concern that people taking black root along with potassium depleting diuretics might have an increased risk for hypokalemia.
Read the full Certified Organic Culver's Root (veronicastrum Virginicum) Dried Root Liquid Extract + Caffeine, Potassium Salicylate, Salicylamide interactionCandesartan Cilexetil, HydrochlorothiazideAtacand HCT
How Candesartan Cilexetil, Hydrochlorothiazide interacts with Culver's Root — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Culver's Root (veronicastrum Virginicum) Dried Root Liquid ExtractDiuretic Drugs Moderate
Interaction Summary
Overuse of black root might compound diuretic-induced potassium loss.There is some concern that people taking black root along with potassium depleting diuretics might have an increased risk for hypokalemia.
Read the full Certified Organic Culver's Root (veronicastrum Virginicum) Dried Root Liquid Extract + Candesartan Cilexetil, Hydrochlorothiazide interactionCaptopril, HydrochlorothiazideAcezide, Capozide
How Captopril, Hydrochlorothiazide interacts with Culver's Root — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Culver's Root (veronicastrum Virginicum) Dried Root Liquid ExtractDiuretic Drugs Moderate
Interaction Summary
Overuse of black root might compound diuretic-induced potassium loss.There is some concern that people taking black root along with potassium depleting diuretics might have an increased risk for hypokalemia.
Read the full Certified Organic Culver's Root (veronicastrum Virginicum) Dried Root Liquid Extract + Captopril, Hydrochlorothiazide interactionChlorothiazideDiuril
How Chlorothiazide interacts with Culver's Root — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Culver's Root (veronicastrum Virginicum) Dried Root Liquid ExtractDiuretic Drugs Moderate
Interaction Summary
Overuse of black root might compound diuretic-induced potassium loss.There is some concern that people taking black root along with potassium depleting diuretics might have an increased risk for hypokalemia.
Read the full Certified Organic Culver's Root (veronicastrum Virginicum) Dried Root Liquid Extract + Chlorothiazide interactionChlorothiazide, MethyldopaAldochlor, Aldoclor 150, Aldoclor 250
How Chlorothiazide, Methyldopa interacts with Culver's Root — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Culver's Root (veronicastrum Virginicum) Dried Root Liquid ExtractDiuretic Drugs Moderate
Interaction Summary
Overuse of black root might compound diuretic-induced potassium loss.There is some concern that people taking black root along with potassium depleting diuretics might have an increased risk for hypokalemia.
Read the full Certified Organic Culver's Root (veronicastrum Virginicum) Dried Root Liquid Extract + Chlorothiazide, Methyldopa interactionChlorothiazide, ReserpineDiupres
How Chlorothiazide, Reserpine interacts with Culver's Root — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Culver's Root (veronicastrum Virginicum) Dried Root Liquid ExtractDiuretic Drugs Moderate
Interaction Summary
Overuse of black root might compound diuretic-induced potassium loss.There is some concern that people taking black root along with potassium depleting diuretics might have an increased risk for hypokalemia.
Read the full Certified Organic Culver's Root (veronicastrum Virginicum) Dried Root Liquid Extract + Chlorothiazide, Reserpine interactionChlorthalidoneHygroton, Thalitone
How Chlorthalidone interacts with Culver's Root — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Culver's Root (veronicastrum Virginicum) Dried Root Liquid ExtractDiuretic Drugs Moderate
Interaction Summary
Overuse of black root might compound diuretic-induced potassium loss.There is some concern that people taking black root along with potassium depleting diuretics might have an increased risk for hypokalemia.
Read the full Certified Organic Culver's Root (veronicastrum Virginicum) Dried Root Liquid Extract + Chlorthalidone interactionChlorthalidone, ClonidineClorpres, Combipres
How Chlorthalidone, Clonidine interacts with Culver's Root — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Culver's Root (veronicastrum Virginicum) Dried Root Liquid ExtractDiuretic Drugs Moderate
Interaction Summary
Overuse of black root might compound diuretic-induced potassium loss.There is some concern that people taking black root along with potassium depleting diuretics might have an increased risk for hypokalemia.
Read the full Certified Organic Culver's Root (veronicastrum Virginicum) Dried Root Liquid Extract + Chlorthalidone, Clonidine interactionCryptenamine, MethyclothiazideDiutensen
How Cryptenamine, Methyclothiazide interacts with Culver's Root — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Culver's Root (veronicastrum Virginicum) Dried Root Liquid ExtractDiuretic Drugs Moderate
Interaction Summary
Overuse of black root might compound diuretic-induced potassium loss.There is some concern that people taking black root along with potassium depleting diuretics might have an increased risk for hypokalemia.
Read the full Certified Organic Culver's Root (veronicastrum Virginicum) Dried Root Liquid Extract + Cryptenamine, Methyclothiazide interactionCyclothiazideAnhydron, Fluidil
How Cyclothiazide interacts with Culver's Root — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Culver's Root (veronicastrum Virginicum) Dried Root Liquid ExtractDiuretic Drugs Moderate
Interaction Summary
Overuse of black root might compound diuretic-induced potassium loss.There is some concern that people taking black root along with potassium depleting diuretics might have an increased risk for hypokalemia.
Read the full Certified Organic Culver's Root (veronicastrum Virginicum) Dried Root Liquid Extract + Cyclothiazide interactionDeserpidine, HydrochlorothiazideOreticyl, Oreticyl Forte
How Deserpidine, Hydrochlorothiazide interacts with Culver's Root — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Culver's Root (veronicastrum Virginicum) Dried Root Liquid ExtractDiuretic Drugs Moderate
Interaction Summary
Overuse of black root might compound diuretic-induced potassium loss.There is some concern that people taking black root along with potassium depleting diuretics might have an increased risk for hypokalemia.
Read the full Certified Organic Culver's Root (veronicastrum Virginicum) Dried Root Liquid Extract + Deserpidine, Hydrochlorothiazide interactionDeserpidine, MethyclothiazideEnduronyl, Enduronyl Forte
How Deserpidine, Methyclothiazide interacts with Culver's Root — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Culver's Root (veronicastrum Virginicum) Dried Root Liquid ExtractDiuretic Drugs Moderate
Interaction Summary
Overuse of black root might compound diuretic-induced potassium loss.There is some concern that people taking black root along with potassium depleting diuretics might have an increased risk for hypokalemia.
Read the full Certified Organic Culver's Root (veronicastrum Virginicum) Dried Root Liquid Extract + Deserpidine, Methyclothiazide interactionDigoxinDigitek, Lanoxicaps, Lanoxin
How Digoxin interacts with Culver's Root — through 1 ingredient. Tap an ingredient for the detail:
Certified Organic Culver's Root (veronicastrum Virginicum) Dried Root Liquid ExtractDigoxin (lanoxin) Moderate
Interaction Summary
Theoretically, the overuse or abuse of black root can increase the risk of adverse effects of cardiac glycoside drugs.
Read the full Certified Organic Culver's Root (veronicastrum Virginicum) Dried Root Liquid Extract + Digoxin interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Culver's Root with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
certified organic Culver's Root (Veronicastrum virginicum) dried root liquid extract
Digoxin (Lanoxin)
Theoretically, the overuse or abuse of black root can increase the risk of adverse effects of cardiac glycoside drugs. Black root chemically binds with the glycosides while in the gastrointestinal (GI) tract, which may reduce their effectiveness if used concomitantly.
Diuretic Drugs
Overuse of black root might compound diuretic-induced potassium loss.There is some concern that people taking black root along with potassium depleting diuretics might have an increased risk for hypokalemia. Initiation of potassium supplementation or an increase in potassium supplement dose may be necessary for some patients. Some diuretics that can deplete potassium include chlorothiazide (Diuril), chlorthalidone (Thalitone), furosemide (Lasix), hydrochlorothiazide (HCTZ, Hydrodiuril, Microzide), and others.
Warfarin (Coumadin)
Black root has stimulant laxative effects. In some people black root can cause diarrhea. Diarrhea can increase the effects of warfarin, increase international normalized ratio (INR), and increase the risk of bleeding. Advise patients who take warfarin not to take excessive amounts of black root.
Brand information
Manufacturer and brand details for Culver's Root, from the product label.
Culver's Root by Herbal Terra: Common Questions
Does Culver's Root by Herbal Terra interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Can I take Culver's Root if I'm pregnant or breastfeeding?
What side effects might I experience?
Why is this product a concern with warfarin?
What's in this product?
Can I take this with diuretics?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Culver's Root is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Culver's Root’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Culver's Root's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 2 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Black Root 2 references
- Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
- Fetrow CW, Avila JR. Professional's Handbook of Complementary & Alternative Medicines. 1st ed. Springhouse, PA: Springhouse Corp., 1999.
Parts of this content are provided by the Therapeutic Research Center, LLC.
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