D-Mannose 1000 mg Ingredients & Drug Interactions
What is this page for?
First and foremost: checking D-Mannose 1000 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
D-Mannose 1000 mg is a dietary supplement by We Like Vitamins with 2 active ingredients. Its ingredients are commonly taken for preventing urinary tract infections (utis), treating mild utis, urinary tract health.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.
HelloPharmacist Scorecard of D-Mannose 1000 mg by We Like Vitamins
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains one active ingredient: D-mannose at 1,000 mg per capsule. D-mannose is a simple sugar (a monosaccharide) that your body doesn't metabolize the way it does glucose—most of it passes through and gets filtered into your urine.
The capsule itself is made from gelatin with rice powder and magnesium stearate as inactive ingredients (fillers and flow agents that help the powder move through the manufacturing equipment).
Does it work?
Leans against
The evidence for D-mannose is mixed. It's rated likely effective for carbohydrate-deficient glycoprotein syndrome type 1b, a rare genetic condition affecting how your body makes certain proteins.
For urinary tract infections (UTIs), though, it's rated possibly ineffective—meaning the evidence doesn't support that it prevents or treats them the way some manufacturers claim.
How safe is it?
Well-documented data
D-mannose is generally well tolerated in the short term, but long-term safety data are limited—we just don't have enough high-quality studies following people over months or years. The most common side effects are bloating, diarrhea, and nausea.
Diarrhea is more likely if you take a single dose larger than about 200 mg per kilogram of body weight (or if you take high doses for extended periods, like 2 grams daily for 6 months). There isn't enough reliable safety data to recommend it during pregnancy, so if you're pregnant, talk with your doctor first.
Safety while breastfeeding is also not well studied, so caution is advised if you're nursing.
Meds to double-check
No known interactions
No interactions are documented in our data for D-mannose. That said, if you take diabetes medication or anything else you're unsure about, check your specific drugs with the tool on this page before you start.
The bottom line
Scorecard at a glanceFully disclosed formula with graded evidence leaning against its stated purpose. No medication interactions are currently documented, and safety information is well characterized.
D-mannose is most useful if you have carbohydrate-deficient glycoprotein syndrome type 1b and your doctor recommends it—that's where the evidence is strongest. If you're taking it for UTIs, be aware the evidence doesn't support that use.
Watch for diarrhea and bloating, especially if you're taking it long-term or at high doses. Talk with your doctor or pharmacist before starting, especially if you're pregnant, breastfeeding, or have diabetes.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Mar 25, 2021.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about D-Mannose 1000 mg, straight from the product label.
| Brand | We Like Vitamins |
|---|---|
| Barcode (UPC) | X0017VX4NH |
| Net contents | 180 Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Mar 25, 2021 |
| DSLD ID | 244191 |
| Product type | Fiber And Other Nutrients |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Gluten Free, Dairy Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for D-Mannose 1000 mg by We Like Vitamins, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Calories | 4 Calorie(s) | -- |
| Total Carbohydrates | 1 Gram(s) | -- |
| Sugar | 1 Gram(s) | -- |
| D-Mannose | 1000 mg | -- |
Other ingredients: Gelatin, Rice powder, Magnesium Stearate
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Suggested use: For adults, take two (2) capsule daily, preferably with a meal or as directed by a healthcare professional. As a reminder, always discus all supplements with your health care provider.
Precautions
Warning: If you are pregnant, nursing, taking any medications, have or have had a health condition, or planning a medical procedure, consult your doctor before use.
Discontinue use and consult your doctor if any adverse reactions occur.
Keep out of reach of children.
Not intended for use by persons under the age of 18.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Storage
Store in a cool, dry place. Avoid excessive heat or moisture.
Formulation
Helps to support healthy urinary tract Helps to support healthy liver function
Zero: preservatives, artificial colors, artificial flavors, yeast, milk or milk derivatives, lactose, salt, sodium, soy, gluten, starch, or wheat.
FDA Statement of Identity
Dietary Supplement
General Statements
Vitamin angels proud supporter Every bottle counts every item you purchase from us helps to provide life-changing vitamins to a mother or child in need. Thank you!
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
D-Mannose 1000 mg by We Like Vitamins label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in D-Mannose 1000 mg by We Like Vitamins
These are the 2 active ingredients this product is made of. Select any to open its full monograph.
Serving size2 Capsule(s) Dosage formCapsule Servings per container90 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Sugar
D-Mannose
No knowninteractions
D-mannose is a natural sugar most often used to help prevent urinary tract infections, especially those caused by E. coli. Early research is promising...
D-Mannose monograph & interactionsOther (inactive) ingredients: Gelatin, Rice powder, Magnesium Stearate. These complete the product’s ingredient list but are not active constituents.
D-Mannose 1000 mg by We Like Vitamins Drug Interactions
We don’t currently list any known drug interactions for the mapped ingredients in D-Mannose 1000 mg. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.
Brand information
Manufacturer and brand details for D-Mannose 1000 mg, from the product label.
We Like Vitamins
See all We Like Vitamins products- Name
- We Like Vitamins
- Street Address
- 7125 Headley St. #51
- City
- Ada
- State
- MI
- ZipCode
- 49301
- Web Address
- welikevitamins.com
D-Mannose 1000 mg by We Like Vitamins: Common Questions
Does D-Mannose 1000 mg by We Like Vitamins interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Will D-mannose help prevent urinary tract infections?
What are the most common side effects?
Can I take this while pregnant?
Is it safe to breastfeed while taking D-mannose?
Does long-term use have good safety data?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if D-Mannose 1000 mg is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind D-Mannose 1000 mg’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
D-Mannose 1000 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 6 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
D-mannose 6 references
- Westphal V, Kjaergaard S, Davis JA, et al. Genetic and metabolic analysis of the first adult with congenital disorder of glycosylation type Ib: long-term outcome and effects of mannose supplementation. Mol Genet Metab 2001;73:77-85. PubMed
- Kranjcec B, Papes D, Altarac S. D-mannose powder for prophylaxis of recurrent urinary tract infections in women: a randomized clinical trial. World J Urol. 2014 Feb;32(1):79-84.
- de Lonlay P, Seta N. The clinical spectrum of phosphomannose isomerase deficiency, with an evaluation of mannose treatment for CDG-Ib. Biochim Biophys Acta. 2009;1792(9):841-3. PubMed
- Harms HK, Zimmer KP, Kurnik K, Bertele-Harms RM, Weidinger S, Reiter K. Oral mannose therapy persistently corrects the severe clinical symptoms and biochemical abnormalities of phosphomannose isomerase deficiency. Acta Paediatr. 2002;91(10):1065-72. DOI
- . Damen G, de Klerk H, Huijmans J, den Hollander J, Sinaasappel M. Gastrointestinal and other clinical manifestations in 17 children with congenital disorders of glycosylation type Ia, Ib, and Ic. J Pediatr Gastroenterol Nutr. 2004;38(3):282-7. DOI
- Lenger SM, Bradley MS, Thomas DA, Bertolet MH, Lowder JL, Sutcliffe S. D-mannose vs other agents for recurrent urinary tract infection prevention in adult women: a systematic review and meta-analysis. Am J Obstet Gynecol. 2020;223(2):265.e1-265.e13. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC