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Dietary supplement

White Mulberry Leaf Extract 1000 mg Ingredients & Drug Interactions

by We Like Vitamins

White Mulberry Leaf Extract 1000 mg label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking White Mulberry Leaf Extract 1000 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

White Mulberry Leaf Extract 1000 mg is a dietary supplement by We Like Vitamins with 1 active ingredient. Its ingredients are commonly taken for blood sugar support, high cholesterol, weight management.Based on those ingredients, 87 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are White Mulberry leaf extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against White Mulberry Leaf Extract 1000 mg by We Like Vitamins

Ask about any prescription or over-the-counter medication and we check it for interactions with White Mulberry Leaf Extract 1000 mg by We Like Vitamins — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of White Mulberry Leaf Extract 1000 mg by We Like Vitamins

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: white mulberry leaf extract at 1000 mg per capsule. White mulberry leaf is the concentrated extract of the leaf from the white mulberry plant, used traditionally to help with blood sugar and other health concerns.

The capsule itself is made from gelatin and rice powder as inactive ingredients.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see White Mulberry's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: supports healthy glucose levels and appetite control.
  • We looked for evidence on: Diabetes, Impaired glucose tolerance (prediabetes), Obesity, Blood sugar management, Weight management.
  • The closest evidence on file: White Mulberry is rated "Insufficient Reliable Evidence To Rate" for Diabetes (Natural Medicines).
  • Also on file: White Mulberry is rated "Insufficient Reliable Evidence To Rate" for Obesity, Impaired glucose tolerance (prediabetes).

The evidence on white mulberry leaf extract isn't established for the conditions we hold data on. For androgenic alopecia (pattern hair loss), osteoporosis, common cold, diabetes, and high cholesterol, the research is insufficient to rate whether it actually works.

We can't tell you whether this product will deliver on any of those uses based on the clinical evidence available.

The evidence, ingredient by ingredient White Mulberry

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

White mulberry leaf appears to be well tolerated overall when taken orally — most side effects are digestive and mild. In one clinical study using 4.6 grams three times daily for 4 weeks, about half of participants experienced bloating and flatulence, a quarter had loose stools, and a fifth had constipation.

The good news is that for some people these effects seem to ease as you keep taking it, though they may linger for others. For pregnancy and breastfeeding, there isn't enough safety data.

The guidance advises against medicinal amounts during pregnancy and while breastfeeding — talk with your doctor or pharmacist for personalized advice based on your situation.

Side effects, ingredient by ingredient White Mulberry

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — White Mulberry.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 87 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this supplement, check whether you're on any antidiabetes drugs — white mulberry leaf can lower blood sugar, so the risk of low blood sugar (hypoglycemia) is Moderate if combined. Also check for OCT2 substrates, a class of medications that rely on kidney transporters for clearance (Moderate severity).

Use the medication search tool on this page to verify your exact prescriptions.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

This extract is generally well tolerated, but it's not the product to start without checking your medications first. If you take diabetes drugs or medications cleared through your kidneys, you need to run them through the checker below.

Talk to your pharmacist before you begin — it'll take two minutes and could prevent a real problem.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Feb 25, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about White Mulberry Leaf Extract 1000 mg, straight from the product label.

Brand We Like Vitamins
Net contents 200 Capsule(s)
Market status On market
Date entered into DSLD Feb 25, 2021
DSLD ID 244296
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for White Mulberry Leaf Extract 1000 mg by We Like Vitamins, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
100
IngredientAmount% DV
White Mulberry leaf extract1000 mg--

Other ingredients: Gelatin, Rice powder

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested use: For adults, take two (2) capsules daily, preferably with a meal or as directed by a healthcare professional. Always discus all supplements with your health care provider.

Precautions

Warning: If you are pregnant, nursing, taking any medications, have or have had a health condition, or planning a medical procedure, consult your doctor before use.

Discontinue use and consult your doctor if any adverse reactions occur.

Keep out of reach of children.

Not intended for use by persons under the age of 18.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Storage

Store in a cool, dry place. Avoid excessive heat or moisture.

Formulation

Helps to support healthy glucose levels Helps to support appetite control

Zero: preservatives, artificial colors, artificial flavors, yeast, corn, milk or milk derivatives, lactose, salt, sodium, soy, sugar, gluten, starch, or wheat.

FDA Statement of Identity

Dietary Supplement

General Statements

Vitamin angels proud supporter Every bottle counts Every item you purchase from us helps to provide life-changing vitamins to a mother or child in need. Thank you!

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

White Mulberry Leaf Extract 1000 mg by We Like Vitamins label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

White Mulberry Leaf Extract 1000 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in White Mulberry Leaf Extract 1000 mg by We Like Vitamins

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size2 Capsule(s) Dosage formCapsule Servings per container100 Amounts shown are per serving.

White Mulberry leaf extract

Interacts with
87 drugs
1000 mg per serving Form: Alkaloids, Flavonoids

White mulberry leaf is most studied for helping blunt the rise in blood sugar after meals, but the human evidence is limited and not strong. It is gen...

White Mulberry leaf extract monograph & interactions

Other (inactive) ingredients: Gelatin, Rice powder. These complete the product’s ingredient list but are not active constituents.

Interaction report

White Mulberry Leaf Extract 1000 mg by We Like Vitamins Drug Interactions

Want to check YOUR meds against White Mulberry Leaf Extract 1000 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
87Drugs
87 Moderate

Ingredients driving the most interactions

White Mulberry leaf extract 87

Individual Drug Interactions

The ingredients in White Mulberry Leaf Extract 1000 mg interact with 87 drugs. Click any drug to see the details.

1 of the 1 ingredient in White Mulberry Leaf Extract 1000 mg interact with drugs. Each result below shows which ingredient is responsible. White Mulberry leaf extract

Each ingredient & the kinds of drugs it affects

For each ingredient in White Mulberry Leaf Extract 1000 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

White Mulberry leaf extract2 drug types · 87 drugs

Antidiabetes Drugs

Theoretically, white mulberry leaf might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Clinical research shows that white mulberry leaf can lower blood glucose levels. Advise patients to monitor glucose levels closely.

Likelihood Possible Evidence D
Organic Cation Transporter 2 (Oct2) Substrates

Theoretically, white mulberry leaf might slow the elimination and increase the adverse effects of drugs which are OCT2 substrates.
Animal research shows that coadministration of white mulberry leaf extract with metformin, an OCT2 substrate, slows the renal elimination of metformin via inhibition of OCT2 activity. OCT2 is expressed in the kidneys and is responsible for transporting cationic drugs into tubular epithelial cells in order to be excreted in the urine.

Likelihood Possible Evidence D
White Mulberry leaf extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for White Mulberry Leaf Extract 1000 mg, from the product label.

We Like Vitamins

See all We Like Vitamins products
Name
We Like Vitamins
Street Address
7125 Headley St. #51
City
Ada
State
MI
ZipCode
49301
Web Address
welikevitamins.com
Pharmacist Counseling Corner

White Mulberry Leaf Extract 1000 mg by We Like Vitamins: Common Questions

Does White Mulberry Leaf Extract 1000 mg by We Like Vitamins interact with any medications?
Yes. Based on its ingredients, White Mulberry Leaf Extract 1000 mg has a known interaction with 87 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
White Mulberry Leaf Extract 1000 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will this lower my blood sugar if I don't have diabetes?
White mulberry leaf can lower blood glucose, so yes — theoretically it could affect your blood sugar even if you don't have diabetes. That's why it's especially important to check your medications first, and if you take any diabetes drug, your doctor will want to monitor your levels closely.
What's the most common side effect?
Digestive issues — bloating, flatulence, loose stools, and constipation are the ones we see reported. In one study, half of people taking it had bloating and gas, but the good news is these effects often ease off over a few weeks.
Can I take this if I'm pregnant or breastfeeding?
There isn't enough safety data for medicinal amounts during pregnancy or breastfeeding. Talk with your doctor or pharmacist — they can weigh your individual situation and help you decide what's right for you.
Does this product actually work for diabetes or high cholesterol?
The research evidence isn't strong enough for us to say. For diabetes, high cholesterol, osteoporosis, hair loss, and common cold, the data we have rates as insufficient — we can't tell you whether it actually delivers on those claims.
What does 'OCT2 substrate' mean, and should I worry about it?
OCT2 is a kidney transporter — a gatekeeper that helps clear certain drugs from your body. White mulberry leaf may slow that process, so drugs that rely on it could build up in your system. Metformin is one example. That's why checking your medications with us is important.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if White Mulberry Leaf Extract 1000 mg is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

White Mulberry Leaf Extract 1000 mg label
Go deeper

The Full Monographs Behind White Mulberry Leaf Extract 1000 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

White Mulberry

Interacts with 87 drugs

White mulberry leaf is most studied for helping blunt the rise in blood sugar after meals, but the human evidence is limited and not strong. It is generally well tolerated as a food and tea,...

Read the full White Mulberry monograph →
Sources

Sources & How We Checked

White Mulberry Leaf Extract 1000 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 6 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

White Mulberry 6 references
  1. Andallu B, Suryakantham V, Lakshmi Srikanthi B, Reddy GK. Effect of mulberry (Morus indica L.) therapy on plasma and erythrocyte membrane lipids in patients with type 2 diabetes. Clin Chim Acta 2001;314:47-53. PubMed
  2. Mudra M, Ercan-Fang N, Zhong L, et al. Influence of mulberry leaf extract on the blood glucose and breath hydrogen response to ingestion of 75 g sucrose by type 2 diabetic and control subjects. Diabetes Care 2007;30:1272-4. PubMed
  3. Kimura T, Nakagawa K, Kubota H, et al. Food-grade mulberry powder enriched with 1-deoxynojirimycin suppresses the elevation of postprandial blood glucose in humans. J Agric Food Chem 2007;55:5869-74. PubMed
  4. Huh HW, Na YG, Bang KH, et al. Extended intake of mulberry leaf extract delayed metformin elimination via inhibiting the organic cation transporter 2. Pharmaceutics. 2020;12(1):49. PubMed
  5. Thaipitakwong T, Supasyndh O, Rasmi Y, Aramwit P. A randomized controlled study of dose-finding, efficacy, and safety of mulberry leaves on glycemic profiles in obese persons with borderline diabetes. Complement Ther Med. 2020;49:102292. PubMed
  6. Thondre PS, Lightowler H, Ahlstrom L, Gallagher A. Mulberry leaf extract improves glycaemic response and insulaemic response to sucrose in healthy subjects: results of a randomized, double blind, placebo-controlled study. Nutr Metab (Lond) 2021;18(1):41. PubMed

See these in context on the White Mulberry monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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