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Dietary supplement

Elderberry 450 mg Ingredients & Drug Interactions

by We Like Vitamins

Capsule Category: Botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Elderberry 450 mg is a dietary supplement by We Like Vitamins with 1 active ingredient. Its ingredients are commonly taken for colds, flu (influenza), other respiratory infections.Based on those ingredients, 121 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Elderberry. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Elderberry 450 mg by We Like Vitamins

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: elderberry extract at 450 mg per capsule. The inactive ingredients are gelatin and rice powder.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Elderberry's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: immune system support and antioxidant protection.
  • We looked for evidence on: Upper respiratory tract infection (URTI), Lower respiratory tract infections, Respiratory tract infections, Common cold, Influenza.
  • The closest evidence on file: Elderberry is rated "Insufficient Reliable Evidence To Rate" for Respiratory tract infections (Natural Medicines).
  • Also on file: Elderberry is rated "Insufficient Reliable Evidence To Rate" for Upper respiratory tract infection (URTI), Lower respiratory tract infections.

The evidence for elderberry isn't established yet in our data. We hold insufficient reliable evidence to rate it for allergic rhinitis (hay fever), cardiovascular disease, chronic fatigue syndrome, chronic obstructive pulmonary disease, cognitive function, or respiratory tract infections.

That doesn't mean it doesn't work—it means the research so far hasn't been strong or complete enough to say.

The evidence, ingredient by ingredient Elderberry

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Properly prepared elderberry products are generally well tolerated. The key word is prepared: raw or unripe berries, seeds, leaves, and bark contain compounds that can cause nausea, vomiting, severe diarrhea, weakness, dizziness, numbness, and even confusion.

Cooking removes that toxin, so a supplement like this one should be safe on that front. Rare case reports include nausea, vomiting, and in one instance liver inflammation tied to long-term elderberry use in someone with autoimmune disease.

There isn't enough reliable safety information to know whether elderberry is safe during pregnancy or while breastfeeding, so the data advises against it during both. Talk with your doctor or pharmacist about whether this product is right for you if you're pregnant, planning pregnancy, or nursing.

Side effects, ingredient by ingredient Elderberry

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Elderberry.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: immunosuppressants / transplant drugs.
  • For scale: 121 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take this product, double-check with your pharmacist or doctor if you're on immunosuppressants (drugs used after organ transplant or for autoimmune conditions) or pazopanib (a cancer medication). Both are Moderate-severity interactions.

If you don't take either of these, no other interactions are documented for the ingredients we could check—but that's not a guarantee none exist, so run your full medication list through the tool below to be sure.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

If you don't take immunosuppressants or pazopanib, and you're not pregnant or breastfeeding, properly prepared elderberry is generally well tolerated. If you do take either of those medications, check with your doctor or pharmacist before starting.

The evidence for what elderberry actually does for colds, hay fever, or other conditions isn't established yet.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Mar 25, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Elderberry 450 mg, straight from the product label.

Brand We Like Vitamins
Barcode (UPC) X001P8YCFB
Net contents 200 Capsule(s)
Market status On market
Date entered into DSLD Mar 25, 2021
DSLD ID 244196
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Elderberry 450 mg by We Like Vitamins, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
200
UPC/BARCODE
X001P8YCFB
IngredientAmount% DV
Elderberry450 mg--

Other ingredients: Gelatin, Rice powder

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested use: For adults, take one (1) capsule 1 to 3 times daily or as directed by your healthcare provider. As a reminder, always discuss all supplements with your health care provider.

Precautions

Warning: If you are pregnant, nursing, taking any medications, have or have had a health condition, or planning a medical procedure, consult your doctor before use.

Discontinue use and consult your doctor if any adverse reactions occur.

Not intended for use by persons under the age of 18. Keep out of reach of children.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Storage

Store in a cool dry place. Avoid excessive heat or moisture.

Formulation

Helps support immune system Helps protect against free radicals

Zero: preservatives, artificial colors, artificial flavors, yeast, corn, milk or milk derivatives, lactose, salt, sodium, soy, sugar, gluten, starch, or wheat.

FDA Statement of Identity

Dietary Supplement

General Statements

Vitamin angels proud supporter Every bottle counts Every time you purchase from us helps to provide life-changing vitamins to a mother or child in need. Thank you!

See for yourself

Elderberry 450 mg by We Like Vitamins label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Elderberry 450 mg by We Like Vitamins

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container200 Amounts shown are per serving.

Elderberry

Interacts with
121 drugs
450 mg per serving

Elderberry is a popular herbal supplement, mainly taken to help with colds and flu. Some small studies suggest it may modestly shorten cold or flu sym...

Elderberry monograph & interactions

Other (inactive) ingredients: Gelatin, Rice powder. These complete the product’s ingredient list but are not active constituents.

Interaction report

Elderberry 450 mg by We Like Vitamins Drug Interactions

Want to check YOUR meds against Elderberry 450 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
121Drugs
121 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Elderberry 450 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Elderberry2 drug types · 121 drugs

Immunosuppressants

Theoretically, elderberry might interfere with immunosuppressant therapy due to its immunostimulant activity.
Elderberry has immunostimulant activity, increasing the production of cytokines, including interleukin and tumor necrosis factor.

Likelihood Possible Evidence B
Pazopanib (Votrient)

Theoretically, elderberry might interact with pazopanib, potentially increasing the risk of adverse effects.
In one case, a 65-year-old patient taking pazopanib for 4 weeks for soft-tissue sarcoma developed severe nausea, loose stools, and elevated alanine transaminase and aspartate transaminase levels and was diagnosed with grade 3 liver injury. The patient reported taking elderberry supplements for 2 years, dose unspecified, and was also taking a multivitamin and a calcium supplement. The patient's symptoms and liver enzyme levels improved upon discontinuation of pazopanib and all supplements. Pazopanib treatment was re-initiated, at a lower dose, with no further evidence of liver injury. It was unclear in this case report if the elderberry supplements were derived from the berry, the flower, or the combination.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Elderberry 450 mg, from the product label.

We Like Vitamins

See all We Like Vitamins products
Name
We Like Vitamins
Street Address
7125 Headley St. #51
City
Ada
State
MI
ZipCode
49301
Web Address
welikevitamins.com
Pharmacist Counseling Corner

Elderberry 450 mg by We Like Vitamins: Common Questions

Does Elderberry 450 mg by We Like Vitamins interact with any medications?
Yes. Based on its ingredients, Elderberry 450 mg has a known interaction with 121 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Elderberry 450 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does elderberry actually work for colds or the flu?
The evidence isn't established yet in our data. We don't have reliable evidence to rate elderberry for respiratory tract infections or other common reasons people take it. That means more research is needed before we can say whether it works.
Is this safe if I'm pregnant or breastfeeding?
No—there isn't enough reliable safety information, so the data advises against it during pregnancy and while breastfeeding. Talk with your doctor or pharmacist about your options.
What are the side effects I should watch for?
When properly prepared (like in this capsule), elderberry is generally well tolerated and side effects are rare. If you do have nausea, vomiting, or diarrhea, it would likely be from raw or unripe berries—not cooked supplements like this one. One rare case report linked long-term use to liver inflammation in someone with autoimmune disease.
Can I take this if I'm on an immunosuppressant medication?
Probably not without checking first. Elderberry stimulates your immune system, which could interfere with drugs designed to suppress it. Talk with your doctor or pharmacist before taking this product if you're on any immunosuppressant.
What's in this besides the elderberry?
The inactive ingredients are gelatin and rice powder—standard capsule materials and a filler.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Elderberry 450 mg is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Elderberry 450 mg label
Sources

Sources & How We Checked

Elderberry 450 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 6 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Elderberry 6 references
  1. Barak V, Halperin T, Kalickman I. The effect of Sambucol, a black elderberry-based, natural product, on the production of human cytokines: I. Inflammatory cytokines. Eur Cytokine Netw 2001;12:290-6..
  2. Elderberry (Sambucus species). The Poison Plant Patch, Novia Scotia Museum, 2007. Available at: http://museum.gov.ns.ca/poison/?section=species&id=117 (Accessed 16 October 2009).
  3. European elder. Canadian Poisonous Plants Information System. Available at: http://www.cbif.gc.ca/pls/pp/ppack.jump?p_null=all&p_psn=121&p_type=all&p_sci=comm&p_x=px (Accessed 16 October 2009).
  4. Raus K, Pleschka S, Klein P, Schoop R, Fisher P. Effect of an echinacea-based hot drink versus oseltamivir in Influenza treatment: a randomized, double-blind, double-dummy, multicenter, noninferiority clinical trial. . Curr Ther Res Clin Exp. 2015;20;77:6 PubMed
  5. Ramachandran A, Antala D, Pudasainee P, Panginikkod S, Gupta H. A Plausible Association Between the Use of Elderberry and Autoimmune Hepatitis. Cureus 2022;14(4):e24250. PubMed
  6. Agarwal N, Mangla A. Elderberry interaction with pazopanib in a patient with soft-tissue sarcoma: A case report and literature review. Mol Clin Oncol 2024;20(5):36. PubMed

See these in context on the Elderberry monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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