No known drug interactions for the matched ingredients — not a guarantee none exist. Based on 1 of 3 ingredients. Check your meds →
Dietary supplement

Digest Gluten Plus Ingredients & Drug Interactions

by Genestra Brands

Capsule Category: Non-nutrient/non-botanical
No known interaction
The interaction bottom line No known interaction

Digest Gluten Plus is a dietary supplement by Genestra Brands with 3 active ingredients. Its ingredients are commonly taken for digestion and bloating, muscle soreness and exercise recovery, inflammation and swelling.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Digest Gluten Plus by Genestra Brands

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 3 of its 3 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

This product has 3 active ingredients, all proteolytic enzymes (proteases) — proteins that break down other proteins. Gluten-specific bacterial protease, acid protease, and alkaline protease work together to digest proteins, particularly gluten.

The capsule also contains inactive ingredients: hypromellose and magnesium stearate.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Proteolytic Enzymes (proteases) product and its label doesn't state a use — see Proteolytic Enzymes (proteases)'s own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

We don't hold effectiveness data for these ingredients in our system, so we can't tell you how well they work for their intended purpose. If you'd like more information on their performance, your pharmacist or the manufacturer can help.

The evidence, ingredient by ingredient Proteolytic Enzymes (proteases)

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

These proteolytic enzymes are generally well tolerated in adults, though some people report digestive upset or allergic reactions. Because proteases are used in laundry products, rarely some people develop allergies to them — usually from airborne or skin exposure at work.

Occupational exposure to airborne pepsin (another protease) has occasionally caused allergic rhinitis or asthma in case reports. During pregnancy, safety has not been established, so it's best avoided unless your doctor prescribes it.

During breastfeeding, there's little safety data, so medical advice is needed before use.

Side effects, ingredient by ingredient Proteolytic Enzymes (proteases)

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for the ingredients we could check.

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. No medication interactions are currently documented, and safety information is well characterized.

Digest Gluten Plus is a protein-digesting enzyme blend intended to help break down gluten. It's generally well tolerated, but people with known protease allergies should be cautious.

If you're pregnant, breastfeeding, or have any concerns, talk with your doctor or pharmacist before starting.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 3 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Feb 23, 2016.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Digest Gluten Plus, straight from the product label.

Brand Genestra Brands
Barcode (UPC) 88319612241
Net contents 90 Vegetable Capsule(s)
Market status On market
Date entered into DSLD Feb 23, 2016
DSLD ID 56324
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other
Intended target group(s) Vegetarian, Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Digest Gluten Plus by Genestra Brands, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
90
UPC/BARCODE
88319612241
IngredientAmount% DV
Gluten Specific Bacterial Protease350 mg--
Acid Protease10 mg--
Alkaline Protease10 mg--

Other ingredients: Hypromellose, Magnesium Stearate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Recommended Adult Dose: Take one capsule daily with a meal or as recommended by your healthcare practitioner.

Precautions

Risk Information: If you are pregnant or breastfeeding, consult your healthcare practitioner prior to use.

Hypersensitivity/allergy has been known to occur; in which case, discontinue use.

Quality Assurance: Safety-sealed for your protection and for product freshness. Do not use if outer seal is missing or broken.

Contains: Milk, wheat

Formulation

Guaranteed to contain no added yeast, corn, soy, sodium, sugar, artificial coloring or flavoring or antimicrobial preservatives.

Ideal for vegetarians.

The capsules are made from 100% pure vegetable sources, free of preservatives and additives.

Storage

Store in a cool, dry place.

General Statements
FDA Statement of Identity

ENZYME SUPPLEMENT

Formula

Contains: Milk, wheat

Seals/Symbols

Seroyal

General

V2.0563

See for yourself

Digest Gluten Plus by Genestra Brands label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Digest Gluten Plus by Genestra Brands

These are the 3 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container90 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Gluten Specific Bacterial Protease

No known
interactions
350 mg per serving Form: Bacillus subtilis

Proteolytic enzymes are proteins that help break down other proteins, and common examples include bromelain (from pineapple), papain (from papaya), tr...

Gluten Specific Bacterial Protease monograph & interactions

Acid Protease

No known
interactions
10 mg per serving Form: Aspergillus oryzae

Proteolytic enzymes are proteins that help break down other proteins, and common examples include bromelain (from pineapple), papain (from papaya), tr...

Acid Protease monograph & interactions

Alkaline Protease

No known
interactions
10 mg per serving Form: Aspergillus oryzae

Proteolytic enzymes are proteins that help break down other proteins, and common examples include bromelain (from pineapple), papain (from papaya), tr...

Alkaline Protease monograph & interactions

Other (inactive) ingredients: Hypromellose, Magnesium Stearate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Digest Gluten Plus by Genestra Brands Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Digest Gluten Plus. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Digest Gluten Plus, from the product label.

Genestra Brands

Name
Seroyal USA
City
Pittsburgh
State
PA
ZipCode
15275
Phone Number
1-888-737-6925
Web Address
seroyal.com
Pharmacist Counseling Corner

Digest Gluten Plus by Genestra Brands: Common Questions

Does Digest Gluten Plus by Genestra Brands interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Digest Gluten Plus. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Digest Gluten Plus contains 3 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What exactly do these enzymes do?
They're proteases — enzymes that break down proteins. The gluten-specific protease targets gluten proteins specifically, while the acid and alkaline proteases work at different points in your digestive tract to further break down proteins you eat.
Can I take this if I'm allergic to laundry detergent?
Possibly, but be careful. Proteases are used in some laundry products, and rarely people develop allergies to them. If you've had an allergic reaction to detergent containing enzymes, mention it to your pharmacist before taking this supplement.
Is it safe during pregnancy?
Safety hasn't been established in pregnancy, so it's best avoided unless your doctor prescribes it. Talk with your doctor or pharmacist about whether it's right for you.
Can I take this while breastfeeding?
There's little safety data during breastfeeding, so medical advice is needed. Check with your doctor or pharmacist before starting.
What side effects might I notice?
Most people tolerate it well, but some experience digestive upset or allergic reactions. If you notice unusual symptoms, stop and talk with your pharmacist.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Digest Gluten Plus is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Digest Gluten Plus label
Sources

Sources & How We Checked

Digest Gluten Plus's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 3 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Proteolytic Enzymes (proteases) 3 references
  1. Weeks JA, Harper RA, Simon RA, Burdick JD. Assessment of sensitization risk of a laundry pre-spotter containing protease. Cutan Ocul Toxicol. 2011;30(4):272-9. PubMed
  2. Marquès LI, Lara S, Abós T, Bartolomé B. Occupational rhinitis due to pepsin. J Investig Allergol Clin Immunol. 2006;16(2):136-7. DOI
  3. Cartier A, Malo JL, Pineau L, Dolovich J. Occupational asthma due to pepsin. J Allergy Clin Immunol. 1984;73(5 Pt 1):574-7. PubMed

See these in context on the Proteolytic Enzymes (proteases) monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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