Interactions on record — worth a quick check against your medications. Based on 4 of 10 ingredients. Check your meds →
Dietary supplement

Digestive Enzymes Ingredients & Drug Interactions

by ALLMAX ESSENTIALS

Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Digestive Enzymes is a dietary supplement by ALLMAX ESSENTIALS with 10 active ingredients. Its ingredients are commonly taken for inflammation and swelling, sinus and nasal congestion, digestion support.Based on those ingredients, 141 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Bromelain. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Digestive Enzymes by ALLMAX ESSENTIALS

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 10 active ingredients.
  • “Protein Digestion Complex” is a proprietary blend — the label doesn't break down how much of each component you get.
  • “Lacto-Lipid Digestion Complex” is a proprietary blend — the label doesn't break down how much of each component you get.
  • “Phyto Digestion Complex” is a proprietary blend — the label doesn't break down how much of each component you get.

ALLMAX ESSENTIALS Digestive Enzymes contains 10 active ingredients, all digestive enzymes designed to break down different food components. Bromelain breaks down proteins; protease and protease SP also help digest proteins; lipase handles fats; lactase breaks down milk sugar (lactose); and cellulase, pectinase, glucoamylase, and hemicellulase work on plant fibers and carbohydrates.

Three of these ingredients are listed in proprietary blends (Protein Digestion Complex, Lacto-Lipid Digestion Complex, and Phyto Digestion Complex), which combine several enzymes in each category. The capsules also contain inactive ingredients (fillers and binders): hypromellose, medium chain triglyceride, and maltodextrin.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: digestive support and enzyme supplementation.
  • We looked for evidence on: Dyspepsia, Lactose intolerance, Exercise-induced muscle soreness, Inflammatory bowel disease (IBD), Postoperative swelling, Rhinosinusitis — and 3 related terms.
  • The strongest evidence on file: Lactase is rated "Effective" for Lactose intolerance (Natural Medicines).
  • Also on file: Lipase is rated "Insufficient Reliable Evidence To Rate" for Inflammatory bowel disease (IBD), Dyspepsia.
  • Also on file: Bromelain is rated "Insufficient Reliable Evidence To Rate" for Exercise-induced muscle soreness, Rhinosinusitis, Postoperative swelling.

In our data, lactase is rated effective for lactose intolerance—if you have trouble digesting milk products, this ingredient has evidence behind it. The other enzymes in this product have insufficient evidence: bromelain, for instance, has been studied for hay fever, burns, cancer support, and chronic venous insufficiency, but the research isn't strong enough to say whether it works.

Protease, lipase, and the remaining enzymes similarly lack established effectiveness ratings for digestive support or other conditions in the data we hold.

The evidence, ingredient by ingredient Bromelain Proteolytic Enzymes (proteases) Lipase Lactase

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 4 of the 4 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 4 of 4.
  • General safety write-ups exist for 4 of 4.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Most of these enzymes are generally well tolerated. Bromelain taken by mouth commonly causes diarrhea, gas, stomach upset, and headache; it can also trigger allergic reactions in sensitive people, especially if inhaled as a powder.

Protease may cause digestive upset or allergies. Lactase is generally well tolerated and likely low-risk.

Lipase has not reported adverse effects in adults, though serious complications (abdominal pain, bleeding) can occur in premature infants receiving a specific medical form. During pregnancy, bromelain safety data advises against it.

Protease should be avoided in pregnancy unless prescribed. For lactase, pregnancy data suggests it's likely safe, but check with your doctor.

Limited data exists for lipase and protease in breastfeeding—talk with your healthcare provider first before using regularly.

Side effects, ingredient by ingredient Bromelain Proteolytic Enzymes (proteases) Lipase Lactase

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 4 matched ingredients can interact with medications — Bromelain.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 141 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check before taking if you're on blood thinners or antiplatelet drugs (like warfarin, clopidogrel, or aspirin)—bromelain may increase bleeding risk. Also check if you take tetracycline antibiotics, since bromelain may change how they're absorbed.

No interactions are documented in our data for the other checked enzymes, but we couldn't verify several ingredients because we don't hold their interaction data.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with clinical evidence supporting its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This enzyme blend may help people with lactose intolerance, but evidence for digestive support overall is limited in our data. If you take blood thinners, antiplatelet drugs, or tetracycline antibiotics, you'll want to check with us or your pharmacist first—bromelain may interact with these.

Pregnant or breastfeeding? Talk with your doctor before starting, especially regarding bromelain.

Otherwise, it's usually well tolerated for short-term use.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 5 of 10 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Feb 23, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Digestive Enzymes, straight from the product label.

Brand ALLMAX ESSENTIALS
Barcode (UPC) 665553202372
Net contents 90 Capsule(s)
Market status On market
Date entered into DSLD Feb 23, 2025
DSLD ID 325795
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Kosher, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Digestive Enzymes by ALLMAX ESSENTIALS, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
90
UPC/BARCODE
665553202372
IngredientAmount% DV
Amylase0 NP--
Bromelain0 NP--
Protease0 NP--
Lipase0 NP--
Lactase0 NP--
Cellulase0 NP--
Pectinase0 NP--
Glucoamylase0 NP--
Hemicellulase0 NP--
Protein Digestion Complex0 NP--
Lacto-Lipid Digestion Complex0 NP--
Phyto Digestion Complex0 NP--
Protease SP0 NP--

Other ingredients: Hypromellose, Medium Chain Triglyceride, Maltodextrin

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Professional Grade Supplements

Considering the high levels of protein in our diets, ALLMAX has ensured that the protein digestion complex is very high in digestive activity and has 4 different variations with different pH levels to ensure maximum protein absorption. Enhanced protein absorption leads to increased levels of plasma amino acids and nitrogen retention levels, both esssential for growth and recovery.

Vegan

+ Enhanced Nutrient Digestion + Optimal Protein Absorption

Vegan Caps

Product of USA

General Statements

When the food we eat are cooked or processed, they lose their natural enzymes. Lacking these crucial enzymes, our bodies take on the added burden of enzyme production. This can lead to an over worked pancreas and a reduction in the quality of digestion. In addition, as we age, our levels of enzyme production drop even further. Even a small decrease in nutrient digestion can lead to gas, bloating and indigestion. Indigested fats can become rancid (toxic), indigested carbs feed colonic bacterial strains and indigested proteins can pass through the intestinal mucosa leading to allergic immune responses. Optimal digestion increases the nutrients that our bodies need. It decreases the digestive load placed on our bodies when we consume enzyme-depleted foods.

With as much as 90% of typical diet coming from cooked, boiled, baked, microwaved, barbecued, processed and shelf-stable products - digestive enzymes are a must.

Formula

11 different enzyme forms have been recruited to supply a truly full spectrum of highly active enzymes.

Kosher Certified

+ 11 Highly-Active Enzymes

Seals/Symbols

Lab Tested Every Lot cGMP Registered Facility Kosher Certified

Purity & Potency Tested Quality Guarantee

Brand IP Statement(s)

Copyright 2021 ALLMAX Nutrition Inc. All rights reserved. Trademarks are property of their respective owners.

Science Innovation Quality Results ALLMAX Essentials

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Directions of Use: Take 1 capsule before each meal. If you are eating larger than normal portions, take 2 capsules.

Precautions

Warnings: This product is to be used by adults only. Keep out of reach of children.

Consult a healthcare practitioner prior to use if; you are pregnant or breastfeeding, you have a gastrointestinal lesion/ulcer, you are taking an anticoagulant/blood thinner or an anti-inflammatory, or are having surgery, or you have diabetes.

Nausea, vomiting, and diarrhea have been known to occur, in which case discontinue use and consult a health care practitioner. Do not use if inner seal is broken.

Hypersensitivity/allergy has been known to occur, in which case discontinue use.

California Warning: Lead is known to the State of California to cause birth defects or reproductive harm. Consuming this product can expose you to more than 0.0000005 g of lead. For more information go to www.P65Warnings.ca.gov. Prop 65

Allergen Warning: Produced in a facility that also handles milk, soy, wheat, egg, peanut, tree nuts, fish, crustacean and shellfish products.

See for yourself

Digestive Enzymes by ALLMAX ESSENTIALS label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Digestive Enzymes by ALLMAX ESSENTIALS

These are the 10 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container90 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Protein Digestion Complex

0 NP per serving

Lacto-Lipid Digestion Complex

0 NP per serving

Phyto Digestion Complex

0 NP per serving
  • › Amylase
  • › Cellulase
  • › Pectinase
  • › Glucoamylase
  • › Hemicellulase

Other (inactive) ingredients: Hypromellose, Medium Chain Triglyceride, Maltodextrin. These complete the product’s ingredient list but are not active constituents.

Interaction report

Digestive Enzymes by ALLMAX ESSENTIALS Drug Interactions

Want to check YOUR meds against Digestive Enzymes?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
141Drugs
122 Moderate 19 Minor

Ingredients driving the most interactions

Bromelain 141

Each ingredient & the kinds of drugs it affects

For each ingredient in Digestive Enzymes with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Bromelain2 drug types · 141 drugs

Anticoagulant/Antiplatelet Drugs

Bromelain may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
There is one case report of a patient experiencing minor bruising while taking bromelain with naproxen. Bromelain is thought to have antiplatelet activity. Whether this interaction is of concern with topical bromelain is unclear. Interference with coagulation of burn wounds has been reported in a patient receiving bromelain-based enzymatic debridement. However, observational research has found that topical bromelain debridement is not associated with increases or decreases in laboratory markers of coagulation when compared with surgical debridement.

Likelihood Possible Evidence D
Tetracycline Antibiotics

Theoretically, bromelain might increase levels of tetracycline antibiotics.
Laboratory research suggests that bromelain might increase the absorption of tetracycline antibiotics. However, a study in healthy adults reported no difference in tetracycline plasma levels when a 500 mg dose was taken with or without bromelain 80 mg.

Likelihood Possible Evidence B
The maker

Brand information

Manufacturer and brand details for Digestive Enzymes, from the product label.

ALLMAX ESSENTIALS

See all ALLMAX ESSENTIALS products
Name
HBS INTERNATIONAL CORP.
Street Address
711 S. Carson St., Suite 4
City
Carson City
State
NV
ZipCode
89701
Web Address
ALLMAXNUTRITION.COM
Pharmacist Counseling Corner

Digestive Enzymes by ALLMAX ESSENTIALS: Common Questions

Does Digestive Enzymes by ALLMAX ESSENTIALS interact with any medications?
Yes. Based on its ingredients, Digestive Enzymes has a known interaction with 141 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Digestive Enzymes contains 10 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm pregnant?
Bromelain in this product should be avoided during pregnancy based on safety data. Protease also should not be used in pregnancy unless your doctor prescribes it. For lactase and lipase, there isn't enough data to know—talk with your doctor or pharmacist for personalized advice before using regularly.
Is this safe while breastfeeding?
Safety data is limited. Bromelain should be avoided; protease is not recommended without medical advice. Lactase and lipase have little safety data during breastfeeding, so check with your healthcare provider first before using regularly.
What side effects might I notice?
Bromelain most commonly causes diarrhea, gas, stomach upset, and headache. Protease may cause digestive upset or allergic reactions. Lactase and lipase rarely cause side effects in adults, though allergic reactions to lactase powder have been reported in workers handling it. Serious allergic reactions (like asthma or throat tightness) are uncommon but possible with enzyme products.
Does this actually help with digestion?
Lactase is rated effective for lactose intolerance—it helps break down milk sugar. For the other enzymes, the evidence isn't established in our data. Bromelain, protease, and lipase haven't been rated as effective for digestive support based on the research we hold.
Why can't you check some of the ingredients?
We don't hold interaction data for amylase, cellulase, pectinase, glucoamylase, and hemicellulase—we simply don't have their safety monographs on file. That doesn't mean they're unsafe, just that we can't verify interactions for them. Stick to the search tool for your medications or ask us directly.
Is there anything in here I might be allergic to?
If you're sensitive to pineapple or papaya proteins, bromelain may trigger a reaction. Protease and lactase can cause allergic responses in sensitive people, especially with airborne exposure to enzyme powders. If you've had reactions to enzyme-based products before, talk with us before starting.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Digestive Enzymes is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Digestive Enzymes label
Sources

Sources & How We Checked

Digestive Enzymes's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 24 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Bromelain 19 references
  1. Nettis E, Napoli G, Ferrannini A, Tursi A. IgE-mediated allergy to bromelain. Allergy 2001;56:257-8. PubMed
  2. Taussig SJ, Batkin S. Bromelain, the enzyme complex of pineapple (Ananas comosus) and its clinical application. An update. J Ethnopharmacol 1988;22:191-203.. PubMed
  3. Bradbrook ID, Morrison PJ, Rogers HJ. The effect of bromelain on the absorption of orally administered tetracycline. Br J Clin Pharmacol 1978;6:552-4. PubMed
  4. Bush TM, Rayburn KS, Holloway SW, et al. Adverse interactions between herbal and dietary substances and prescription medications: a clinical survey. Altern Ther Health Med 2007;13:30-5.
  5. Brien S, Lewith G, Walker AF, et al. Bromelain as an adjunctive treatment for moderate-to-severe osteoarthritis of the knee: a randomized placebo-controlled pilot study. QJM 2006;99:841-50. PubMed
  6. Mori S, Ojima Y, Hirose T, et al. The clinical effect of proteolytic enzyme containing bromelain and trypsin on urinary tract infection evaluated by double blind method. Acta Obstet Gynaecol Jpn 1972;19:147-53.
  7. Glaser D, Hilberg T. The influence of bromelain on platelet count and platelet activity in vitro. Platelets 2006;17:37-41. PubMed
  8. Heinicke R M, van der Wal L, Yokoyama M. Effect of bromelain (Ananase) on human platelet aggregation. Experientia 1972;28:844-5. PubMed
  9. Gailhofer, G., Wilders-Truschnig, M., Smolle, J., and Ludvan, M. Asthma caused by bromelain: an occupational allergy. Clin Allergy 1988;18(5):445-450. PubMed
  10. Mattei, O., Fabri, G., and Farina, G. [Occupational health experience regarding four cases of asthma due to bromelain (author's transl)]. Medicina del Lavoro 1979;70(5):404-409.
  11. Galleguillos, F. and Rodriguez, J. C. Asthma caused by bromelin inhalation. Clin Allergy 1978;8(1):21-24. PubMed
  12. Perez-Camo I, Quirce S, Duran MA, and et al. Latex allergy: evidence of cross-reactivity with papain and bromelain [abstract]. Allergy 1996;51(suppl 31):48.
  13. Martin GJ, Ehrenreich J, and Asbell N. Bromelain: pineapple proteases with anti-edema activity. Exp Med Surg 1962;20:227-247.
  14. Kasemsuk T, Saengpetch N, Sibmooh N, Unchern S. Improved WOMAC score following 16-week treatment with bromelain for knee osteoarthritis. Clin Rheumatol. 2016 Oct;35(10):2531-40. PubMed
  15. Kutlu Ö, DemirbaS A, Elmas ÖF, Güvenç U, Metin A. Fixed drug eruption: a new side effect of bromelain. Contact Dermatitis 2020. Online ahead of print. PubMed
  16. Shoham Y, Shapira E, Haik J, et al. Bromelain-based enzymatic debridement of chronic wounds: Results of a multicentre randomized controlled trial. Wound Repair Regen 2021;29(6):899-907. PubMed
  17. Pfister P, Garcia Wendel PD, Kim BS, et al. Coagulation side effects of enzymatic debridement in burned patients. Burns 2022. PubMed
  18. Hasham S, Riyat H, Fletcher A, O'Boyle CP, Alexander S. To bleed or not to bleed? Case series and discussion of haemorrhage risk with enzymatic debridement in burn injuries. Scars Burn Heal 2023;9:20595131231168333. PubMed
  19. Leelakanok N, Petchsomrit A, Janurai T, Saechan C, Sunsandee N. Efficacy and safety of bromelain: A systematic review and meta-analysis. Nutr Health 2023. PubMed

See these in context on the Bromelain monograph →

Proteolytic Enzymes (proteases) 3 references
  1. Weeks JA, Harper RA, Simon RA, Burdick JD. Assessment of sensitization risk of a laundry pre-spotter containing protease. Cutan Ocul Toxicol. 2011;30(4):272-9. PubMed
  2. Marquès LI, Lara S, Abós T, Bartolomé B. Occupational rhinitis due to pepsin. J Investig Allergol Clin Immunol. 2006;16(2):136-7. DOI
  3. Cartier A, Malo JL, Pineau L, Dolovich J. Occupational asthma due to pepsin. J Allergy Clin Immunol. 1984;73(5 Pt 1):574-7. PubMed

See these in context on the Proteolytic Enzymes (proteases) monograph →

Lipase 1 reference
  1. Casper C, Hascoet JM, Ertl T, et al. Recombinant bile salt-stimulated lipase in preterm infant feeding: A randomized phase 3 study. PLoS One. 2016;11(5):e0156071. PubMed

See these in context on the Lipase monograph →

Lactase 1 reference
  1. Laukkanen A, Ruoppi P, Remes S, Koistinen T, Mäkinen-Kiljunen S. Lactase-induced occupational protein contact dermatitis and allergic rhinoconjunctivitis. Contact Dermatitis. 2007;57(2):89-93. PubMed

See these in context on the Lactase monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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