DMAE Ingredients & Drug Interactions
What is this page for?
First and foremost: checking DMAE against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
DMAE is a dietary supplement by Swanson Premium Brand with 3 active ingredients. Its ingredients are commonly taken for morning sickness in pregnancy, premenstrual syndrome (pms), preventing or treating b6 deficiency.Based on those ingredients, 527 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are DMAE, Vitamin B6, Pantethine. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against DMAE by Swanson Premium Brand
Ask about any prescription or over-the-counter medication and we check it for interactions with DMAE by Swanson Premium Brand — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of DMAE by Swanson Premium Brand
Four independent checks of what is known — a summary of the available information, not a grade of the product itself.
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
The stated purpose hasn't been mapped to our evidence data yet.
Why this rating?
- We haven't mapped this product's purpose to our evidence data yet — it'll be graded on the next content refresh.
Every active ingredient lists its own amount on the label.
Why this rating?
- The label discloses an exact amount for 3 of its 3 active ingredients.
- No proprietary blends here — you can verify the dose of every single component.
The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.
Why this rating?
- 3 of the 3 matched ingredients can interact with medications — Deanol, Vitamin B6, Pantethine.
- The most serious interaction on file is rated Moderate.
- Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; Parkinson's medications.
- For scale: 527 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.
Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.
Why this rating?
- We hold adverse-effect (side-effect) data for 3 of the 3 matched ingredients.
- Pregnancy & breastfeeding safety ratings cover 3 of 3.
- General safety write-ups exist for 3 of 3.
- Remember: this measures how much safety information exists. Thin data is not the same as being safe.
HelloPharmacist summaryFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
Assessment coverage: 3 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated May 28, 2019.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about DMAE, straight from the product label.
| Brand | Swanson Premium Brand |
|---|---|
| Barcode (UPC) | 087614018713 |
| Net contents | 100 Capsule(s) |
| Market status | Off market |
| Date entered into DSLD | May 28, 2019 |
| DSLD ID | 202755 |
| Product type | Other Combinations |
| Supplement form | Capsule |
| Dietary claims / uses | All Other |
| Intended target group(s) | Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for DMAE by Swanson Premium Brand, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Vitamin B6 | 10 mg | 588% |
| Pantethine | 50 mg | -- |
| DMAE | 130 mg | -- |
Other ingredients: Microcrystalline Cellulose, Gelatin, Calcium Pantothenate, May contain one or both of the following
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements
Bringing wellness to the world since 1969
To reorder, call toll free 1-800-437-4148 or visit our website at www.swansonvitamins.com
FDA Statement of Identity
Dietary Supplement
Seals/Symbols
Guaranteed purity & potency
Precautions
Do not use if seal is broken.
Keep out of reach of children.
Warning: Do not use if you are pregnant or nursing.
Consult your healthcare provider before using this product if you have a medical condition, especially depression, schizophrenia or epilepsy.
Storage
Store in a cool, dry place.
Suggested/Recommended/Usage/Directions
Suggested Use: As a dietary supplement, take one capsule one to two times per day with water.
General
SW871 Rev 1 10 30 18
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
DMAE by Swanson Premium Brand label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in DMAE by Swanson Premium Brand
These are the 3 active ingredients this product is made of. Select any to open its full monograph.
Serving size1 Capsule(s) Dosage formCapsule Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Vitamin B6
Interacts with210 drugs
Vitamin B6 (pyridoxine) is an essential water-soluble vitamin that your body needs for metabolism, brain function, and making red blood cells. It is b...
Vitamin B6 monograph & interactionsPantethine
Interacts with122 drugs
Pantethine is a derivative of vitamin B5 (pantothenic acid) that some studies suggest may modestly lower cholesterol and triglycerides. The evidence i...
Pantethine monograph & interactionsDMAE
Interacts with219 drugs
Deanol (DMAE) is a compound related to choline that is marketed for memory, focus, and mood, but solid human evidence for most of these uses is limite...
DMAE monograph & interactionsOther (inactive) ingredients: Microcrystalline Cellulose, Gelatin, Calcium Pantothenate, May contain one or both of the following. These complete the product’s ingredient list but are not active constituents.
DMAE by Swanson Premium Brand Drug Interactions
DMAE contains 3 ingredients, and 3 of them have known drug interactions. Altogether they interact with 527 medications. Here’s the picture, then you can look up your own drug.
Want to check YOUR meds against DMAE?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in DMAE interact with 527 drugs. Click any drug to see the details.
3 of the 3 ingredients in DMAE interact with drugs. Each result below shows which ingredient is responsible. DMAE Vitamin B6 Pantethine
AprocitentanTryvio
How Aprocitentan interacts with DMAE — through 1 ingredient. Tap an ingredient for the detail:
Vitamin B6Antihypertensive Drugs Moderate
Interaction Summary
Theoretically, vitamin B6 may have additive effects when used with antihypertensive drugs.
Read the full Vitamin B6 + Aprocitentan interactionArgatrobanArgatroban
How Argatroban interacts with DMAE — through 1 ingredient. Tap an ingredient for the detail:
PantethineAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, pantethine might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Pantethine + Argatroban interactionAspirinAngettes 75, ASA, Asaphen, Aspirin, Caprin, Cartia +8 more
How Aspirin interacts with DMAE — through 1 ingredient. Tap an ingredient for the detail:
PantethineAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, pantethine might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Pantethine + Aspirin interactionAspirin, Aluminum Hydroxide, Codeine Phosphate, Magnesium HydroxideAscriptin Codeine #3
How Aspirin, Aluminum Hydroxide, Codeine Phosphate, Magnesium Hydroxide interacts with DMAE — through 1 ingredient. Tap an ingredient for the detail:
PantethineAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, pantethine might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Pantethine + Aspirin, Aluminum Hydroxide, Codeine Phosphate, Magnesium Hydroxide interactionAspirin, ButalbitalAxotal
How Aspirin, Butalbital interacts with DMAE — through 1 ingredient. Tap an ingredient for the detail:
PantethineAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, pantethine might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Pantethine + Aspirin, Butalbital interactionAspirin, Butalbital, CaffeineFiorinal
How Aspirin, Butalbital, Caffeine interacts with DMAE — through 1 ingredient. Tap an ingredient for the detail:
PantethineAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, pantethine might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Pantethine + Aspirin, Butalbital, Caffeine interactionAspirin, Butalbital, Caffeine, Codeine PhosphateFiorinal w/ Codeine
How Aspirin, Butalbital, Caffeine, Codeine Phosphate interacts with DMAE — through 1 ingredient. Tap an ingredient for the detail:
PantethineAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, pantethine might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Pantethine + Aspirin, Butalbital, Caffeine, Codeine Phosphate interactionAspirin, Butalbital, Caffeine, PhenacetinMarnal
How Aspirin, Butalbital, Caffeine, Phenacetin interacts with DMAE — through 1 ingredient. Tap an ingredient for the detail:
PantethineAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, pantethine might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Pantethine + Aspirin, Butalbital, Caffeine, Phenacetin interactionAspirin, CaffeineAnacin
How Aspirin, Caffeine interacts with DMAE — through 1 ingredient. Tap an ingredient for the detail:
PantethineAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, pantethine might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Pantethine + Aspirin, Caffeine interactionAspirin, Caffeine, Codeine PhosphateAnacin w/ Codeine
How Aspirin, Caffeine, Codeine Phosphate interacts with DMAE — through 1 ingredient. Tap an ingredient for the detail:
PantethineAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, pantethine might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Pantethine + Aspirin, Caffeine, Codeine Phosphate interactionAspirin, Caffeine, Dihydrocodeine BitartrateSynalgos DC
How Aspirin, Caffeine, Dihydrocodeine Bitartrate interacts with DMAE — through 1 ingredient. Tap an ingredient for the detail:
PantethineAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, pantethine might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Pantethine + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionAspirin, Caffeine, Dover's PwdAcedoval, Dovacet
How Aspirin, Caffeine, Dover's Pwd interacts with DMAE — through 1 ingredient. Tap an ingredient for the detail:
PantethineAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, pantethine might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Pantethine + Aspirin, Caffeine, Dover's Pwd interactionAspirin, Caffeine, HydrocodoneDamason-P
How Aspirin, Caffeine, Hydrocodone interacts with DMAE — through 1 ingredient. Tap an ingredient for the detail:
PantethineAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, pantethine might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Pantethine + Aspirin, Caffeine, Hydrocodone interactionAspirin, Caffeine, Isobutylallylbarbituric Acid, PhenacetinLanorinal
How Aspirin, Caffeine, Isobutylallylbarbituric Acid, Phenacetin interacts with DMAE — through 1 ingredient. Tap an ingredient for the detail:
PantethineAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, pantethine might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Pantethine + Aspirin, Caffeine, Isobutylallylbarbituric Acid, Phenacetin interactionAspirin, Caffeine, OrphenadrineInvagesic, Invagesic Forte, Norgesic, Norgesic Forte, Orphengesic, Orphengesic Forte
How Aspirin, Caffeine, Orphenadrine interacts with DMAE — through 1 ingredient. Tap an ingredient for the detail:
PantethineAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, pantethine might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Pantethine + Aspirin, Caffeine, Orphenadrine interactionAspirin, Caffeine, Phenacetin, PropoxypheneMargesic Comp. 65
How Aspirin, Caffeine, Phenacetin, Propoxyphene interacts with DMAE — through 1 ingredient. Tap an ingredient for the detail:
PantethineAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, pantethine might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Pantethine + Aspirin, Caffeine, Phenacetin, Propoxyphene interactionAspirin, Calcium Carbonate, Magnesium Carbonate, Magnesium OxideBufferin
How Aspirin, Calcium Carbonate, Magnesium Carbonate, Magnesium Oxide interacts with DMAE — through 1 ingredient. Tap an ingredient for the detail:
PantethineAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, pantethine might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Pantethine + Aspirin, Calcium Carbonate, Magnesium Carbonate, Magnesium Oxide interactionAspirin, CarisoprodolSoma Compound
How Aspirin, Carisoprodol interacts with DMAE — through 1 ingredient. Tap an ingredient for the detail:
PantethineAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, pantethine might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Pantethine + Aspirin, Carisoprodol interactionAspirin, Carisoprodol, Codeine PhosphateSoma Compound w/ Codeine
How Aspirin, Carisoprodol, Codeine Phosphate interacts with DMAE — through 1 ingredient. Tap an ingredient for the detail:
PantethineAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, pantethine might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Pantethine + Aspirin, Carisoprodol, Codeine Phosphate interactionAspirin, Chlorpheniramine, PhenylpropanolamineAlka-Seltzer Plus Cold
How Aspirin, Chlorpheniramine, Phenylpropanolamine interacts with DMAE — through 2 ingredients. Tap an ingredient for the detail:
PantethineAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, pantethine might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Pantethine + Aspirin, Chlorpheniramine, Phenylpropanolamine interactionDmaeAnticholinergic Drugs Minor
Interaction Summary
Theoretically, deanol might decrease the effectiveness of anticholinergic drugs.
Read the full Dmae + Aspirin, Chlorpheniramine, Phenylpropanolamine interactionAspirin, Citric Acid, Sodium BicarbonateAlka-Seltzer Pain Reliever and Antacid
How Aspirin, Citric Acid, Sodium Bicarbonate interacts with DMAE — through 1 ingredient. Tap an ingredient for the detail:
PantethineAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, pantethine might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Pantethine + Aspirin, Citric Acid, Sodium Bicarbonate interactionAspirin, Codeine PhosphateAspirin w/ Codeine
How Aspirin, Codeine Phosphate interacts with DMAE — through 1 ingredient. Tap an ingredient for the detail:
PantethineAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, pantethine might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Pantethine + Aspirin, Codeine Phosphate interactionAspirin, Codeine Phosphate, MethocarbamolRobaxisal C
How Aspirin, Codeine Phosphate, Methocarbamol interacts with DMAE — through 1 ingredient. Tap an ingredient for the detail:
PantethineAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, pantethine might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Pantethine + Aspirin, Codeine Phosphate, Methocarbamol interactionAspirin, Codeine Phosphate, PhenobarbitalPhenaphen
How Aspirin, Codeine Phosphate, Phenobarbital interacts with DMAE — through 2 ingredients. Tap an ingredient for the detail:
Vitamin B6Phenobarbital (luminal) Moderate
Interaction Summary
High doses of vitamin B6 may reduce the levels and clinical effects of phenobarbital.
Read the full Vitamin B6 + Aspirin, Codeine Phosphate, Phenobarbital interactionPantethineAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, pantethine might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Pantethine + Aspirin, Codeine Phosphate, Phenobarbital interactionAspirin, Diphenhydramine, PhenylpropanolamineAlka Seltzer Plus Night Time Effervescent
How Aspirin, Diphenhydramine, Phenylpropanolamine interacts with DMAE — through 2 ingredients. Tap an ingredient for the detail:
PantethineAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, pantethine might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Pantethine + Aspirin, Diphenhydramine, Phenylpropanolamine interactionDmaeAnticholinergic Drugs Minor
Interaction Summary
Theoretically, deanol might decrease the effectiveness of anticholinergic drugs.
Read the full Dmae + Aspirin, Diphenhydramine, Phenylpropanolamine interactionAspirin, DipyridamoleAggrenox, Asasantin Retard
How Aspirin, Dipyridamole interacts with DMAE — through 1 ingredient. Tap an ingredient for the detail:
PantethineAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, pantethine might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Pantethine + Aspirin, Dipyridamole interactionAspirin, Ethoheptazine, MeprobamateEquagesic
How Aspirin, Ethoheptazine, Meprobamate interacts with DMAE — through 1 ingredient. Tap an ingredient for the detail:
PantethineAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, pantethine might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Pantethine + Aspirin, Ethoheptazine, Meprobamate interactionAspirin, HydrocodoneAlor 5 500, Lortab ASA
How Aspirin, Hydrocodone interacts with DMAE — through 1 ingredient. Tap an ingredient for the detail:
PantethineAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, pantethine might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Pantethine + Aspirin, Hydrocodone interactionAspirin, MeprobamateMicrainin
How Aspirin, Meprobamate interacts with DMAE — through 1 ingredient. Tap an ingredient for the detail:
PantethineAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, pantethine might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Pantethine + Aspirin, Meprobamate interactionAspirin, MethocarbamolRobaxisal
How Aspirin, Methocarbamol interacts with DMAE — through 1 ingredient. Tap an ingredient for the detail:
PantethineAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, pantethine might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Read the full Pantethine + Aspirin, Methocarbamol interactionEach ingredient & the kinds of drugs it affects
For each ingredient in DMAE with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
DMAE
Anticholinergic Drugs
Theoretically, deanol might decrease the effectiveness of anticholinergic drugs.
Deanol is thought to increase acetylcholine levels.
Cholinergic Drugs
Theoretically, deanol might increase the effects and adverse effects of cholinergic drugs.
Deanol is thought to increase acetylcholine levels.
Vitamin B6
Amiodarone (Cordarone)
Theoretically, vitamin B6 might increase the photosensitivity caused by amiodarone.
Despite initial case reports suggesting that pyridoxine may have a protective effect against amiodarone-induced photosensitivity, preliminary clinical research suggests that pyridoxine may actually exacerbate this adverse effect.
Antihypertensive Drugs
Theoretically, vitamin B6 may have additive effects when used with antihypertensive drugs.
Research in hypertensive rats shows that vitamin B6 can decrease systolic blood pressure. Similarly, clinical research in patients with hypertension shows that taking high doses of vitamin B6 may reduce systolic and diastolic blood pressure, possibly by reducing plasma levels of epinephrine and norepinephrine.
Phenobarbital (Luminal)
High doses of vitamin B6 may reduce the levels and clinical effects of phenobarbital.
Preliminary clinical evidence suggests that vitamin B6 200 mg daily can reduce plasma levels of phenobarbital, possibly by increasing metabolism. It is not known whether lower doses have any effect. Advise people taking phenobarbital to avoid high doses of vitamin B6.
Phenytoin (Dilantin)
High doses of vitamin B6 may reduce the levels and clinical effects of phenytoin.
Preliminary clinical evidence suggests that vitamin B6 200 mg daily can reduce plasma levels of phenytoin, possibly by increasing metabolism. It is not known whether lower doses have any effect. Advise people taking phenytoin to avoid high doses of vitamin B6.
Levodopa
Vitamin B6 may increase the metabolism of levodopa when taken alone, but not when taken in conjunction with carbidopa.
Vitamin B6 (pyridoxine) enhances the metabolism of levodopa, reducing its clinical effects. However, this interaction does not occur when carbidopa is used concurrently with levodopa (Sinemet). Therefore, it is not likely to be a problem in most people.
Pantethine
Anticoagulant/Antiplatelet Drugs
Theoretically, pantethine might increase the risk of bleeding with anticoagulant or antiplatelet drugs.
Some evidence suggests that pantethine reduces platelet aggregation.
Brand information
Manufacturer and brand details for DMAE, from the product label.
Swanson Premium Brand
See all Swanson Premium Brand products- Name
- Swanson Health Products
- City
- Fargo
- State
- ND
- ZipCode
- 58104
- Phone Number
- 1-800-437-4148
- Web Address
- www.swansonvitamins.com
DMAE by Swanson Premium Brand: Common Questions
Does DMAE by Swanson Premium Brand interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if DMAE is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind DMAE’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Vitamin B6
Interacts with 210 drugsVitamin B6 (pyridoxine) is an essential water-soluble vitamin that your body needs for metabolism, brain function, and making red blood cells. It is best known for helping with pregnancy-rel...
Read the full Vitamin B6 monograph → Herb & supplement monographPantethine
Interacts with 122 drugsPantethine is a derivative of vitamin B5 (pantothenic acid) that some studies suggest may modestly lower cholesterol and triglycerides. The evidence is limited and not strong enough to repla...
Read the full Pantethine monograph → Herb & supplement monographDeanol
Interacts with 219 drugsDeanol (DMAE) is a compound related to choline that is marketed for memory, focus, and mood, but solid human evidence for most of these uses is limited or mixed. It can cause side effects in...
Read the full Deanol monograph →Sources & How We Checked
DMAE's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 56 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Vitamin B6 32 references
- Hansten PD, Horn JR. Drug Interactions Analysis and Management. Vancouver, WA: Applied Therapeutics Inc., 1997 and updates.
- Yates AA, Schlicker SA, Suitor CW. Dietary reference intakes: The new basis for recommendations for calcium and related nutrients, B vitamins, and choline. J Am Diet Assoc 1998;98:699-706. PubMed
- Geerling BJ, Dagnelie PC, Badart-Smook A, et al. Diet as a risk factor for the development of ulcerative colitis. Am J Gastroenterol 2000;95:1008-13. PubMed
- South M. Neonatal seizures after pyridoxine use -- reply. Lancet 1999;354:2083. PubMed
- Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline (2000). Washington, DC: National Academy Press, 2000. Available at: http://b
- Baxter P, Aicardi J. Neonatal seizures after pyridoxine use. Lancet 1999;354:2082-3. PubMed
- Bendich A, Cohen M. Vitamin B6 safety issues. Ann N Y Acad Sci 1990;585:321-30.
- Schaumburg H, Kaplan J, Windebank A. Sensory neuropathy from pyridoxine abuse. A new megavitamin syndrome. N Engl J Med 1983;309:445-8. PubMed
- Gordon N. Pyridoxine dependency: an update. Dev Med Child Neurol 1997;39:63-5. PubMed
- Lewis PJ. Pain in the hand and wrist. Pyridoxine supplements may help patients with carpal tunnel syndrome. BMJ 1995;310:1534. PubMed
- Kaufman G. Pyridoxine against amiodarone-induced photosensitivity (letter). Lancet 1984;1:51-2. PubMed
- Mulrow JP, Mulrow CD, McKenna WJ. Pyridoxine and amiodarone-induced photosensitivity. Ann Intern Med 1985;103:68-9. PubMed
- Kawada A, Kashima A, Shiraishi H, et al. Pyridoxine-induced photosensitivity and hypophosphatasia. Dermatology 2000;201:356-60.. PubMed
- Vasile A, Goldberg R, Kornberg B. Pyridoxine toxicity: report of a case. J Am Osteopath Assoc 1984;83:790-1. DOI
- Hansson O, Sillanpaa M. Pyridoxine and serum concentration of phenytoin and phenobarbitone. Lancet 1976;1:256. DOI
- Jansen T, Romiti R, Kreuter A, Altmeyer P. Rosacea fulminans triggered by high-dose vitamins B6 and B12. J Eur Acad Dermatol Venereol 2001;15:484-5..
- Chittumma P, Kaewkiattikun K, Wiriyasiriwach B. Comparison of the effectiveness of ginger and vitamin B6 for treatment of nausea and vomiting in early pregnancy: a randomized double-blind controlled trial. J Med Assoc Thai 2007;90:15-20.
- Hatzitolios, A., Iliadis, F., Katsiki, N., and Baltatzi, M. Is the anti-hypertensive effect of dietary supplements via aldehydes reduction evidence based? A systematic review. Clin Exp.Hypertens. 2008;30(7):628-639. PubMed
- Vasdev, S., Ford, C. A., Parai, S., Longerich, L., and Gadag, V. Dietary vitamin B6 supplementation attenuates hypertension in spontaneously hypertensive rats. Mol.Cell Biochem. 1999;200(1-2):155-162.
- de, Vogel S., Dindore, V., van, Engeland M., Goldbohm, R. A., van den Brandt, P. A., and Weijenberg, M. P. Dietary folate, methionine, riboflavin, and vitamin B-6 and risk of sporadic colorectal cancer. J Nutr 2008;138(12):2372-2378. PubMed
- Hagen, I., Nesheim, B. I., and Tuntland, T. No effect of vitamin B-6 against premenstrual tension. A controlled clinical study. Acta Obstet.Gynecol.Scand. 1985;64(8):667-670. PubMed
- Aybak, M., Sermet, A., Ayyildiz, M. O., and Karakilcik, A. Z. Effect of oral pyridoxine hydrochloride supplementation on arterial blood pressure in patients with essential hypertension. Arzneimittelforschung. 1995;45(12):1271-1273.
- Lal, K. J., Dakshinamurti, K., and Thliveris, J. The effect of vitamin B6 on the systolic blood pressure of rats in various animal models of hypertension. J Hypertens. 1996;14(3):355-363. PubMed
- Lauritzen CH, Reuter HD, Repges R, Bohnert K, and Schmidt U. Treatment of premenstrual tension syndrome with Vitex agnus castus. Controlled, double-blind study versus pyridoxine. Phytomed 1997;4(3):183-189. PubMed
- Fonseca VA, Lavery LA, Thethi TK, et al. Metanx in type 2 diabetes with peripheral neuropathy: A randomized trial. Am J Med 2013;126(2):141-9. PubMed
- Hankey GJ, Eikelboom JW, Yi Q, et al. Treatment with B vitamins and incidence of cancer in patients with previous stroke or transient ischemic attack: Results of a randomized placebo-controlled trial. Stroke 2012;43(6):1572-7. PubMed
- Hoyer-Kuhn H, Kohbrok S, Volland R, Franklin J, Hero B, Beck BB, Hoppe B. Vitamin B6 in primary hyperoxaluria I: first prospective trial after 40 years of practice. Clin J Am Soc Nephrol. 2014 Mar;9(3):468-77. PubMed
- Mahmoud A, Tabassum S, Al Enazi S, et al. Amelioration of levetiracetam-induced behavioral side effects by pyridoxine. A randomized double blind controlled study. Pediatr Neurol 2021;119:15-21. PubMed
- Gupta M, Gallante B, Bamberger JN, et al. Prospective randomized evaluation of idiopathic hyperoxaluria treatments. J Endourol 2021;35(12):1844-1851. PubMed
- Li H, Chen M, Liang S, et al. Excessive vitamin B6 during treatment is related to poor prognosis of patients with nasopharyngeal carcinoma: A U-shaped distribution suggests low dose supplement. Clin Nutr 2021;40(4):2293-2300. PubMed
- Tanigawa J, Nabatame S, Tominaga K, et al. High-dose pyridoxine treatment for inherited glycosylphosphatidylinositol deficiency. Brain Dev 2021;43(6):680-687. PubMed
- Committee on Practice Bulletins-Obstetrics. ACOG Practice Bulletin No. 189: Nausea And Vomiting Of Pregnancy. Obstet Gynecol. 2018;131(1):e15-e30. PubMed
Pantethine 9 references
- Da Col PG, Cattin L, Fonda M, et al. Pantethine in the treatment of hypercholesterolemia: a randomized double-blind trial versus tiadenol. Curr Ther Res 1984;36:314-22.
- Rubba P, Postaiglione B, De Simone F, et al. Comparative evaluation of the lipid-lowering effects of fenofibrate and pantethine in type II hyperlipoproteinemia. Curr Ther Res 1985;38:719-27.
- Coronel F, Tornero F, Torrente J, et al. Treatment of hyperlipemia in diabetic patients on dialysis with a physiological substance. Am J Nephrol 1991;11:32-6.. PubMed
- Agrati AM, Ambrosi G, Ferraro G, Palmieri. Gemfibrozil efficacy vs pantethine in dyslipoproteinemic patients: a controlled study. Curr Ther Res 1989;45:650-63.
- Rumberger, J. A., Napolitano, J., Azumano, I., Kamiya, T., and Evans, M. Pantethine, a derivative of vitamin B(5) used as a nutritional supplement, favorably alters low-density lipoprotein cholesterol metabolism in low- to moderate-cardiovascular risk No
- Hiramatsu, K., Nozaki, H., and Arimori, S. Influence of pantethine on platelet volume, microviscosity, lipid composition and functions in diabetes mellitus with hyperlipidemia. Tokai J.Exp.Clin.Med. 1981;6(1):49-57.
- McRae MP. Treatment of hyperlipoproteinemia with pantethine: A review and analysis of efficacy and tolerability. Nutrition Res 2005;25:319-333. DOI
- Cattin, L., Da Col, P. G., Fonda, M., Mameli, M. G., and Fergulio, G. A. Treatment of hypercholesterolemia with pantethine and fenofibrate; open randomized study on 43 subjects. Current Therapeutic Research 1985;38(Sep):386-395.
- Evans M, Rumberger JA, Azumano I, Napolitano JJ, Citrolo D, Kamiya T. Pantethine, a derivative of vitamin B5, favorably alters total, LDL and non-HDL cholesterol in low to moderate cardiovascular risk subjects eligible for statin therapy: a triple-blinded
Deanol 15 references
- Davies C, Maidment S, Hanley P, et al. Dimethylaminoethanol (DMAE). HSE. Risk assessment document; EH72/2;1997. (TOXLINE).
- Re O. 2-Dimethylaminoethanol (deanol): a brief review of its clinical efficacy and postulated mechanism of action. Curr Ther Res Clin Exp 1974;16:1238-42.
- Pieralisi G, Ripari P, Vecchiet L. Effects of a standardized ginseng extract combined with dimethylaminoethanol bitartrate, vitamins, minerals, and trace elements on physical performance during exercise. Clin Ther 1991;13:373-82.
- George J, Pridmore S, Aldous D. Double blind controlled trial of deanol in tardive dyskinesia. Aust N Z J Psychiatry 1981;15:68-71. PubMed
- Penovich P, Morgan JP, Kerzner B, et al. Double-blind evaluation of deanol in tardive dyskinesia. JAMA 1978;239:1997-8. DOI
- de Montigny C, Chouinard G, Annable L. Ineffectiveness of deanol in tardive dyskinesia: a placebo controlled study. Psychopharmacology (Berl) 1979;65:219-23. PubMed
- Lindeboom SF, Lakke JP. Deanol and physostigmine in the treatment of L-dopa-induced dyskinesias. Acta Neurol Scand 1978;58:134-8. PubMed
- Jus A, Villeneuve A, Gautier J, et al. Deanol, lithium and placebo in the treatment of tardive dyskinesia. A double-blind crossover study. Neuropsychobiology 1978;4:140-9. PubMed
- Lewis JA, Young R. Deanol and methylphenidate in minimal brain dysfunction. Clin Pharmacol Ther 1975;17:534-40. PubMed
- Fisman M, Mersky H, Helmes E. Double-blind trial of 2-dimethylaminoethanol in Alzheimer's disease. Am J Psychiatry 1981;138:970-2. PubMed
- Ferris SH, Sathananthan G, Gershon S, et al. Senile dementia: treatment with deanol. J Am Geriatr Soc 1977;25:241-4. PubMed
- Haug BA, Holzgraefe M. Orofacial and respiratory tardive dyskinesia: potential side effects of 2-dimethylaminoethanol (deanol)? Eur Neurol 1991;31:423-5. PubMed
- Casey DE. Mood alterations during deanol therapy. Psychopharmacology (Berl) 1979;62:187-91. PubMed
- Sergio W. Use of DMAE (2-dimethylaminoethanol) in the induction of lucid dreams. Med Hypotheses 1988;26:255-7. PubMed
- Osol A, Hoover JE, eds. Remington's Pharmaceutical Science, 15th ed. Easton, PA: Mack Publishing Company, 1975.
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