Interactions on record — worth a quick check against your medications. Based on 3 of 5 ingredients. Check your meds →
Dietary supplement

Eleg Fem Ingredients & Drug Interactions

by Ayush Herbs

Eleg Fem label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Eleg Fem against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Eleg Fem is a dietary supplement by Ayush Herbs with 5 active ingredients. Its ingredients are commonly taken for heart health and circulation, digestive problems (constipation, diarrhea), cholesterol support.Based on those ingredients, 1,227 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Terminalia arjuna, Asparagus racemosus, Dioscorea villosa. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Eleg Fem by Ayush Herbs

Ask about any prescription or over-the-counter medication and we check it for interactions with Eleg Fem by Ayush Herbs — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Eleg Fem by Ayush Herbs

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Partial disclosure
Ingredient Transparency · database check
Partial

Most active ingredients list an amount, but at least one is hidden in a blend or missing.

Why this rating?
  • The label discloses an exact amount for 4 of its 8 active ingredients.
  • “Proprietary Blend” is a proprietary blend — the label gives one combined amount (100 mg) without saying how much of each component you get.
  • “Extracts of” is listed as a grouped ingredient — the label doesn't break down how much of each component you get.

Eleg Fem contains 8 ingredients, including a proprietary blend and extracts. The active components are Cissus quadrangularis (a plant traditionally used for bone and weight-related purposes), Bamboo Manna, Coral powder (a calcium source), Terminalia arjuna (used in Ayurvedic medicine for heart and metabolic health), Cimicifuga racemosa (black cohosh, traditionally used for menopausal symptoms), Dioscorea villosa (wild yam, also linked to menopausal support), Asparagus racemosus (used traditionally to support female wellness), and Saraca asoca.

The capsule itself is vegetarian.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: Women's health and menopausal symptom support.
  • We looked for evidence on: Menopausal symptoms, Breast cancer-related hot flashes, Premenstrual syndrome (PMS), Dysmenorrhea, Lactation, Postmenopausal conditions — and 3 related terms.
  • The strongest evidence on file: Black Cohosh is rated "Possibly Effective" for Menopausal symptoms (Natural Medicines).
  • Also on file: Wild Yam is rated "Possibly Ineffective" for Menopausal symptoms.
  • Also on file: Black Cohosh is rated "Insufficient Reliable Evidence To Rate" for Breast cancer-related hot flashes, Breast cancer, Premenstrual syndrome (PMS), Dysmenorrhea.

The evidence for Eleg Fem's individual ingredients is mixed. Cissus quadrangularis is rated possibly effective for obesity, but evidence for other uses—including bone density and cholesterol—is insufficient.

Black cohosh is possibly effective for menopausal symptoms, though wild yam is rated possibly ineffective for the same purpose. Coral powder is likely effective as a bone substitute in surgical settings.

The evidence for Terminalia arjuna, Bamboo Manna, and Asparagus racemosus for the conditions mentioned in traditional use is rated insufficient; we hold no established effectiveness ratings for Saraca asoca.

The evidence, ingredient by ingredient Terminalia Wild Yam Asparagus Racemosus

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 5 of the 7 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 7 of 7.
  • General safety write-ups exist for 7 of 7.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Cissus quadrangularis is generally well tolerated short-term, though long-term safety is not well studied; headache and insomnia have been reported at rates similar to placebo, as have mild digestive side effects. Terminalia arjuna and black cohosh are generally well tolerated in short-term studies, but black cohosh carries rare concerns about liver damage, and Terminalia arjuna's long-term safety varies by product quality.

Wild yam is typically well tolerated, though headache, fever, upset stomach, and vomiting have been reported; anaphylaxis is rare. Bamboo is widely eaten when properly cooked, but supplement safety is not well studied, and raw shoots contain cyanide-like compounds.

Asparagus racemosus is generally considered well tolerated in traditional use, though high-quality safety data are limited. Coral is largely a calcium source but carries quality and contamination concerns.

During pregnancy, the safety data advises against Cissus quadrangularis, Terminalia arjuna, black cohosh, wild yam, and Bamboo Manna; Asparagus racemosus safety is not well established. While breastfeeding, avoid Cissus quadrangularis, Terminalia arjuna, and black cohosh; Bamboo safety is unknown unless cleared by your doctor, and Asparagus racemosus is traditionally used to support milk supply but should be used only under professional guidance.

No pregnancy or breastfeeding data are on file for Saraca asoca or Coral.

Side effects, ingredient by ingredient Terminalia Wild Yam Asparagus Racemosus

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 6 of the 7 matched ingredients can interact with medications — Bamboo, Terminalia, Black Cohosh, Wild Yam, Cissus Quadrangularis, among others.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications; lithium.
  • For scale: 1,228 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking Eleg Fem, double-check these medication types with your pharmacist: drugs broken down by liver pathways (CYP2D6, CYP2C9, CYP3A4 substrates — a very large group including many antidepressants, heart and cancer drugs), blood thinners and antiplatelet drugs, hepatotoxic (liver-damaging) drugs, antidiabetes medications, diuretics (water pills), lithium, estrogen therapy, antithyroid drugs, and serotonergic drugs (antidepressants like SSRIs). No interactions are documented in our data for Coral powder.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glancePartially disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Eleg Fem is a multi-ingredient supplement with documented interactions affecting over 1,200 medications, mostly through Terminalia arjuna's effects on how your liver breaks down drugs, and through black cohosh's liver concerns. If you take any prescription medication—especially blood thinners, diabetes drugs, antidepressants, or liver-metabolized medications—check with your pharmacist or doctor before starting this product.

It's not suitable in pregnancy or while breastfeeding.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 7 of 8 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Apr 25, 2013.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Eleg Fem, straight from the product label.

Brand Ayush Herbs
Barcode (UPC) 891501001135
Net contents 60 Capsule(s)
Market status On market
Date entered into DSLD Apr 25, 2013
DSLD ID 20591
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other
Intended target group(s) Vegetarian, Adult (18 - 50 Years), Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Eleg Fem by Ayush Herbs, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
60
UPC/BARCODE
891501001135
IngredientAmount% DV
Proprietary Blend100 mg--
Cissus quadrangularis0 NP--
Extracts of0 NP--
Bamboo Manna0 NP--
Coral powder0 NP--
Terminalia arjuna100 mg--
Cimicifuga racemosa0 NP--
Dioscorea villosa100 mg--
Asparagus racemosus100 mg--
Saraca asoca100 mg--

Other ingredients: Vegetarian Capsule

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Precautions

Warning: If pregnant, consult your physician before using this or any other product.

Keep Away From Reach Of Children

DO NOT USE IF SEAL IS BROKEN.

Suggested/Recommended/Usage/Directions

SUGGESTED USE: One capsule three times daily or as directed by your physician.

FDA Statement of Identity

DIETARY SUPPLEMENT

General Statements

52010 2-2013

Ayurveda - Wealth of Health

Formulation

Milk, Soy, Egg and Wheat Free.

Formula

Vegetarian

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Eleg Fem by Ayush Herbs label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Eleg Fem label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Eleg Fem by Ayush Herbs

These are the 5 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Extracts of

0 NP per serving

Other (inactive) ingredients: Vegetarian Capsule. These complete the product’s ingredient list but are not active constituents.

Interaction report

Eleg Fem by Ayush Herbs Drug Interactions

Want to check YOUR meds against Eleg Fem?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
1,227Drugs
1,219 Moderate 8 Minor

Ingredients driving the most interactions

Terminalia arjuna 933
Asparagus racemosus 76
Dioscorea villosa 41

Individual Drug Interactions

The ingredients in Eleg Fem interact with 1,227 drugs. Click any drug to see the details.

3 of the 5 ingredients in Eleg Fem interact with drugs. Each result below shows which ingredient is responsible. Terminalia arjuna Asparagus racemosus Dioscorea villosa

Each ingredient & the kinds of drugs it affects

For each ingredient in Eleg Fem with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Terminalia arjuna7 drug types · 933 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, concomitant use of Terminalia arjuna with anticoagulant or antiplatelet drugs may increase the risk of bleeding in some patients.
In vitro, Terminalia arjuna bark extract inhibits platelet aggregation, decreases platelet activation, and shows antithrombotic properties.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, concomitant use of Terminalia bellirica or Terminalia chebula with antidiabetes drugs could affect blood sugar control and increase the risk of hypoglycemia.
Animal and in vitro research shows that Terminalia bellirica and Terminalia chebula fruit and seed extract have hypoglycemic effects.

Likelihood Possible Evidence D
Chlorzoxazone (Parafon Forte, Paraflex)

Theoretically, use of Terminalia chebula may increase the risk of adverse effects from chlorzoxazone.
Animal research shows that enteral administration of Terminalia chebula for 15 days prior to administration of chlorzoxazone increases blood levels of chlorzoxazone and decreases chlorzoxazone clearance. It is speculated that Terminalia chebula reduces the metabolism of chlorzoxazone by inhibiting cytochrome P450 2E1.

Likelihood Possible Evidence D
Cytochrome P450 2C9 (Cyp2C9) Substrates

Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP2C9 substrates.
In vitro research shows that Terminalia arjuna extract inhibits CYP2C9 enzymes and reduces CYP2C9 substrate metabolism.

Likelihood Possible Evidence D
Cytochrome P450 2D6 (Cyp2D6) Substrates

Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP2D6 substrates.
In vitro research shows that Terminalia arjuna extract inhibits CYP2D6 enzymes and reduces CYP2D6 substrate metabolism.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
In vitro research shows that Terminalia arjuna extract inhibits CYP3A4 enzymes and reduces CYP3A4 substrate metabolism.

Likelihood Possible Evidence D
Omeprazole (Prilosec)

Theoretically, use of Terminalia chebula may increase the risk of adverse effects from omeprazole.
Animal research shows that enteral administration of Terminalia chebula for 15 days prior to administration of omeprazole increases blood levels of omeprazole and decreases omeprazole clearance. It is speculated that Terminalia chebula reduces the metabolism of omeprazole by inhibiting cytochrome P450 2C19.

Likelihood Possible Evidence D
Terminalia arjuna full monograph & interactions

Asparagus racemosus2 drug types · 76 drugs

Diuretic Drugs

Theoretically, asparagus racemosus root might increase diuresis and electrolyte loss when used with diuretic drugs.
Animal studies show that asparagus racemosus root has diuretic effects when used in high doses. This effect has not been reported in humans.

Likelihood Possible Evidence D
Lithium

Theoretically, Asparagus racemosus root could reduce excretion and increase levels of lithium.
Animal research suggests that Asparagus racemosus root has diuretic properties when used in high doses. Therefore, it might reduce excretion and increase levels of lithium. The dose of lithium might need to be decreased.

Likelihood Probable Evidence D
Asparagus racemosus full monograph & interactions

Dioscorea villosa1 drug type · 41 drugs

Estrogens

Theoretically, wild yam might increase or decrease the effects of estrogen.
Wild yam root shows estrogenic and anti-estrogenic effects in vitro. Theoretically, wild yam might interfere with hormone therapy.

Likelihood Possible Evidence D
Dioscorea villosa full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Eleg Fem, from the product label.

Ayush Herbs

See all Ayush Herbs products
Name
Ayush Herbs, Inc.
City
Redmond
State
WA
ZipCode
98052
Web Address
www.ayush.com
Pharmacist Counseling Corner

Eleg Fem by Ayush Herbs: Common Questions

Does Eleg Fem by Ayush Herbs interact with any medications?
Yes. Based on its ingredients, Eleg Fem has a known interaction with 1,227 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Eleg Fem contains 5 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will Eleg Fem work for hot flashes and other menopausal symptoms?
Black cohosh, one of the ingredients, is rated possibly effective for menopausal symptoms based on available evidence. However, wild yam, another ingredient here, is rated possibly ineffective for the same purpose. The evidence for the supplement as a whole is not established in our data.
Is Eleg Fem safe to take while I'm pregnant or breastfeeding?
No. The safety data advises against most of the ingredients during pregnancy, including Cissus quadrangularis, Terminalia arjuna, black cohosh, wild yam, and Bamboo Manna. While breastfeeding, several ingredients should be avoided or used only under medical guidance. Talk with your doctor or pharmacist before considering this product if you're pregnant or nursing.
What are the common side effects?
Black cohosh can cause breast tenderness, dizziness, gastrointestinal upset, headache, irritability, rash, and tiredness, though serious side effects are rare. Cissus quadrangularis may cause headache, insomnia, flatulence, diarrhea, and dry mouth at rates similar to placebo. Wild yam may cause headache, fever, and upset stomach. Serious adverse effects like anaphylaxis from wild yam or liver damage from black cohosh are uncommon but possible.
What is Asparagus racemosus in this product for?
Asparagus racemosus is used traditionally in Ayurvedic medicine to support female wellness and lactation. However, the evidence for its effectiveness is rated insufficient; we hold no established proof that it works for any specific condition in our data.
Does Eleg Fem contain fillers or other inactive ingredients besides the active herbs?
The capsule itself is a vegetarian capsule, which is an inactive ingredient. Beyond that, no other inactive ingredients are listed on the label you've provided.
Why does this product interact with so many medications?
Terminalia arjuna is the main culprit—it slows how your liver breaks down three major drug-processing pathways, meaning a wide range of medications can build up to higher levels in your body. Black cohosh also interacts with many drugs because it affects serotonin, estrogen, the liver, and other systems. That's why checking your specific prescriptions is essential.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Eleg Fem is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Eleg Fem label
Go deeper

The Full Monographs Behind Eleg Fem’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Terminalia

Interacts with 933 drugs

Terminalia is a group of traditional Ayurvedic tree species (most notably Terminalia arjuna) used for heart, digestive, and general wellness purposes. Some small studies suggest possible ben...

Read the full Terminalia monograph → Herb & supplement monograph

Wild Yam

Interacts with 41 drugs

Wild yam is a root traditionally used for menopausal symptoms, cramps, and as a so-called 'natural' hormone supplement, but solid human evidence for these uses is lacking. Despite popular cl...

Read the full Wild Yam monograph → Herb & supplement monograph

Asparagus Racemosus

Interacts with 76 drugs

Asparagus racemosus, often called shatavari, is an Ayurvedic herb traditionally used to support women's health, digestion, and overall vitality. Human evidence for most of these uses is limi...

Read the full Asparagus Racemosus monograph →
Sources

Sources & How We Checked

Eleg Fem's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 99 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Cissus Quadrangularis 5 references
  1. Oben J, Kuate D, Agbor G, et al. The use of a Cissus quadrangularis formulation in the management of weight loss and metabolic syndrome. Lipids Health Dis 2006, 5:24.
  2. Oben JE, Ngondi JL, Momo CN, et al. The use of Cissus quadrangularis/Irvingia gabonensis combination in the management of weight loss: a double-blind placebo-controlled study. Lipids Health Dis 2008;7:12.
  3. Panpimanmas, S., Sithipongsri, S., Sukdanon, C., and Manmee, C. Experimental comparative study of the efficacy and side effects of Cissus quadrangularis L. (Vitaceae) to Daflon (Servier) and placebo in the treatment of acute hemorrhoids. J Med Assoc.Thai
  4. Nash R, Azantsa B, Kuate D, Singh H, Oben J. The use of a stem and leaf aqueous extract of Cissus quadrangularis (CQR-300) to reduce body fat and other components of metabolic syndrome in overweight participants. J Altern Complement Med. 2019;25(1):98-106
  5. Benjawan S, Nimitphong H, Tragulpiankit P, Musigavong O, Prathanturarug S, Pathomwichaiwat T. The effect of Cissus quadrangularis L. on delaying bone loss in postmenopausal women with osteopenia: A randomized placebo-controlled trial. Phytomedicine 2022;1 PubMed

See these in context on the Cissus Quadrangularis monograph →

Bamboo 4 references
  1. Chandra AK, Ghosh D, Mukhopadhyay S, et al. Effect of bamboo shoot, Bambusa arundinacea (Retz.) Willd. on thyroid status under conditions of varying iodine intake in rats. Indian J Exp Biol 2004;42(8):781-786.
  2. Kitajima T. Contact allergy caused by bamboo shoots. Contact Dermatitis 1986;15(2):100-102. PubMed
  3. Sang-A-Gad P, Guharat S, Wananukul W. A mass cyanide poisoning from pickling bamboo shoots. Clin Toxicol (Phila). 2011 Nov;49(9):834-9. PubMed
  4. Satya S, Bal LM, Singhal P, Naik SN. Bamboo shoot processing: food quality and safety aspect (a review). Trends in Food Sci. Technol. 2010;21(4):181-9. DOI

See these in context on the Bamboo monograph →

Coral 5 references
  1. Schulz A, Hilgers RD, Niedermeier W. The effect of splinting of teeth in combination with reconstructive periodontal surgery in humans. Clin Oral Investig 2000;4:98-105.. PubMed
  2. Vuola J, Bohling T, Kinnunen J, et al. Natural coral as bone-defect-filling material. J Biomed Mater Res 2000;51:117-22.. DOI
  3. Thalgott JS, Klezl Z, Timlin M, Giuffre JM. Anterior lumbar interbody fusion with processed sea coral (coralline hydroxyapatite) as part of a circumferential fusion. Spine 2002;27:E518-25.. PubMed
  4. Marchac D, Sandor G. Use of coral granules in the craniofacial skeleton. J Craniofac Surg 1994;5:213-7. PubMed
  5. Roux FX, Brasnu D, Menard M, et al. Madreporic coral for cranial base reconstruction. 8 years experience. Acta Neurochir (Wien) 1995;133:201-205. PubMed

See these in context on the Coral monograph →

Terminalia 9 references
  1. Sabu, M. C. and Kuttan, R. Anti-diabetic activity of medicinal plants and its relationship with their antioxidant property. J Ethnopharmacol. 2002;81(2):155-160. PubMed
  2. Rao, N. K. and Nammi, S. Antidiabetic and renoprotective effects of the chloroform extract of Terminalia chebula Retz. seeds in streptozotocin-induced diabetic rats. BMC.Complement Altern.Med 2006;6:17. PubMed
  3. Murali, Y. K., Anand, P., Tandon, V., Singh, R., Chandra, R., and Murthy, P. S. Long-term effects of Terminalia chebula Retz. on hyperglycemia and associated hyperlipidemia, tissue glycogen content and in vitro release of insulin in streptozotocin induced
  4. Senthilkumar, G. P. and Subramanian, S. Evaluation of antioxidant potential of Terminalia chebula fruits studies in streptozotocin-induced diabetic rats. Pharmaceutical Biology (Netherlands) 2007;45:511-518.
  5. Malik N, Dhawan V, Bahl A, Kaul D. Inihbitory effects of Terminalia arjuna on platelet activation in vitro in healthy subjects and patients with coronary artery disease. Platelets. 2009;20(3):183-1190.
  6. Varghese A, Savai J, Pandita N, Gaud RS. In vitro modulatory effects of Terminalia arjuna, arjunic acid, arjunetin, and arjungenin on CYP3A4, CYP2D6, and CYP2C9 enzyme activity in human liver microsomes. Toxicology Reports. 2015(2):806-16. PubMed
  7. Wu G, Dong Z, Dong J, et al. Effects of mongolian medicine Terminalia chebula Retz. on 6 CYP450 enzymes in rats. Int J Clin Exp Pathol 2020;13(12):3128-3138.
  8. Das A, Naveen J, Sreerama YN, Gnanesh Kumar BS, Baskaran V. Low-glycemic foods with wheat, barley and herbs (Terminalia chebula, Terminalia bellerica and Emblica officinalis) inhibit a-amylase, a-glucosidase and DPP-IV activity in high fat and low dose st
  9. Eltimamy M, Elshamarka M, Aboelsaad M, Sayed M, Moawad H. Effects of alcoholic extract of Terminalia Chebula dried fruit on blood biochemical profile in diabetic rats. J Diabetes Metab Disord 2022;21(1):159-170. PubMed

See these in context on the Terminalia monograph →

Black Cohosh 68 references
  1. McFarlin BL, Gibson MH, O'Rear J, Harman P. A national survey of herbal preparation use by nurse-midwives for labor stimulation. Review of the literature and recommendations for practice. J Nurse Midwifery 1999;44:205-16. PubMed
  2. Whiting PW, Clouston A, Kerlin P. Black cohosh and other herbal remedies associated with acute hepatitis. Med J Aust 2002;177:440-3. PubMed
  3. Pepping J. Black cohosh: Cimicifuga racemosa. Am J Health Syst Pharm 1999;56:1400-2. PubMed
  4. Liske E. Therapeutic efficacy and safety of Cimicifuga racemosa for gynecologic disorders. Adv Ther 1998;15:45-53.
  5. Kruse SO, Lohning A, Pauli GF, et al. Fukiic and piscidic acid esters from the rhizome of Cimicifuga racemosa and the in vitro estrogenic activity of fukinolic acid. Planta Med 1999;65:763-4.
  6. Jacobson JS, Troxel AB, Evans J, et al. Randomized trial of black cohosh for the treatment of hot flashes among women with a history of breast cancer. J Clin Oncol 2001;19:2739-45. PubMed
  7. Gunn TR, Wright IM. The use of black and blue cohosh in labour. N Z Med J 1996;109:410-1.
  8. Baillie N, Rasmussen P. Black and blue cohosh in labour. N Z Med J 1997;110:20-1.
  9. Lontos S, Jones RM, Angus PW, Gow PJ. Acute liver failure associated with the use of herbal preparations containing black cohosh. Med J Aust 2003;179:390-1.. DOI
  10. Wuttke W, Seidlova-Wuttke D, Gorkow C. The Cimicifuga preparation BNO 1055 vs. conjugated estrogens in a double-blind placebo-controlled study: effects on menopause symptoms and bone markers. Maturitas 2003;44:S67-77. PubMed
  11. Huntley A, Ernst E. A systematic review of the safety of black cohosh. Menopause 2003;10:58-64.. DOI
  12. Cohen SM, O'Connor AM, Hart J, et al. Autoimmune hepatitis associated with the use of black cohosh: a case study. Menopause 2004;11:575-7. PubMed
  13. Vitetta L, Thomsen M, Sali A. Black cohosh and other herbal remedies associated with acute hepatitis. Med J Aust 2003;178:411-2.. PubMed
  14. Thomsen M, Vitetta L, Schmidt M, Sali A. Acute liver failure associated with the use of herbal preparations containing black cohosh. Med J Aust 2004;180:598-600.. DOI
  15. Cohen B, Schardt D. Center for Science in the Public Interest. Letter to Food and Drug Administration. Commissioner Mark McClellan, MD, PhD. March 4, 2004.
  16. Seidlova-Wuttke D, Hesse O, Jarry H, et al. Evidence for selective estrogen receptor modulator activity in a black cohosh (Cimicifuga racemosa) extract: comparison with estradiol-17beta. Eur J Endocrinol 2003;149:351-62. PubMed
  17. Rockwell S, Liu Y, Higgins SA. Alteration of the effects of cancer therapy agents on breast cancer cells by the herbal medicine black cohosh. Breast Cancer Res Treat 2005;90:233-9. PubMed
  18. Levitsky J, Alli TA, Wisecarver J, Sorrell MF. Fulminant liver failure associated with the use of black cohosh. Dig Dis Sci 2005;50:538-9. PubMed
  19. Cheong JL, Bucknall R. Retinal vein thrombosis associated with a herbal phytoestrogen preparation in a susceptible patient. Postgrad Med J 2005;81:266-7.. PubMed
  20. Nappi RE, Malavasi B, Brundu B, Facchinetti F. Efficacy of Cimicifuga racemosa on climacteric complaints: a randomized study versus low-dose transdermal estradiol. Gynecol Endocrinol 2005;20:30-5.
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Wild Yam 7 references
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See these in context on the Wild Yam monograph →

Asparagus Racemosus 1 reference
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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

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