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Dietary supplement

Ellagic Acid Ingredients & Drug Interactions

by Biotech Nutritions

Capsule Category: Botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Ellagic Acid is a dietary supplement by Biotech Nutritions with 2 active ingredients. Its ingredients are commonly taken for antioxidant support, heart health, oral and gum health.Based on those ingredients, 208 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Red Raspberry extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Ellagic Acid by Biotech Nutritions

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Partial disclosure
Ingredient Transparency · database check
Partial

Most active ingredients list an amount, but at least one is hidden in a blend or missing.

Why this rating?
  • The label discloses an exact amount for 1 of its 2 active ingredients.
  • “Proprietary Blend” is a proprietary blend — the label gives one combined amount (1,120 mg) without saying how much of each component you get.
  • “Red Raspberry extract” is listed as a grouped ingredient — the label doesn't break down how much of each component you get.

This product contains 2 active ingredients: ellagic acid, a polyphenol compound found naturally in berries and other plant foods, and black raspberry powder, which contributes additional plant compounds. The capsule itself is vegetable-based.

Ellagic acid is the main active component here, often studied for potential effects on cell growth and metabolism. Black raspberry adds a whole-food source of similar compounds.

We have no interaction data on file for the red raspberry extract listed in the proprietary blend, so we can't assess whether it adds to the product's profile beyond what ellagic acid and black raspberry provide.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

The label doesn't state a purpose we can grade — see each ingredient's own graded uses on its monograph instead.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence for what this product can actually do is limited. Ellagic acid is rated as having insufficient reliable evidence for bladder cancer, cognitive function, diabetes, melasma, and polycystic ovary syndrome (PCOS).

Black raspberry is also rated as having insufficient evidence for oral cancer, high blood pressure, prediabetes, and metabolic syndrome. In plain terms: these ingredients have been studied, but we don't yet have enough reliable data to say whether they work for any particular condition.

The evidence, ingredient by ingredient Black Raspberry Red Raspberry

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Ellagic acid concentrates are not well studied in humans at supplement doses, so safety data is limited — the product facts recommend caution or avoidance of concentrated forms. In one clinical trial, a combination product containing ellagic acid and another herb caused nausea and diarrhea in a small number of participants, though it's unclear which ingredient was responsible.

Black raspberry is likely safe during pregnancy and lactation when eaten as food, but concentrated supplements lack good safety data. Because ellagic acid itself has no pregnancy and lactation data on file, there isn't enough information to say either way — talk with your doctor or pharmacist if you're pregnant, breastfeeding, or planning to be.

Side effects, ingredient by ingredient Black Raspberry Red Raspberry

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 2 matched ingredients can interact with medications — Ellagic Acid.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 86 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take antidiabetes drugs (blood sugar medications) such as metformin, glipizide, or insulin, talk with your doctor or pharmacist before starting this product — ellagic acid may lower blood sugar and increase the risk of low blood sugar (hypoglycemia). No other medication interactions are documented for the ingredients we could check.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glancePartially disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This product is built around ellagic acid, an ingredient with very limited evidence for the conditions it's studied in and unknown safety at supplement doses. The main medication concern is blood sugar drugs — if you take them, check with your doctor or pharmacist first.

If you're pregnant or breastfeeding, there isn't enough safety data; your doctor or pharmacist can help you decide whether to use it.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Feb 25, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Ellagic Acid, straight from the product label.

Brand Biotech Nutritions
Barcode (UPC) 616983002759
Net contents 60 Capsule(s)
Market status On market
Date entered into DSLD Feb 25, 2021
DSLD ID 243965
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Ellagic Acid by Biotech Nutritions, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
30
UPC/BARCODE
616983002759
IngredientAmount% DV
Proprietary Blend1120 mg--
Ellagic Acid120 mg--
Black Raspberry Powder0 NP--
Red Raspberry extract0 NP--

Other ingredients: Vegetable Capsule

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested use: As a dietary supplement, take two (2) capsules with an 8 oz glass of water, or as directed by a health care professional.

Precautions

Caution: Do not exceed recommended dose.

Pregnant or nursing mothers, children under 18, and individuals with a known medical condition should consult a physician before using this or any dietary supplement.

Pregnant or nursing mothers, children under 18, and individuals with a known medical condition should consult a physician before using this or any dietary supplement.

Keep out of the reach of children.

Do not use if safety seal is damaged or missing.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Seals/Symbols

Made in USA GMP Good Manufacturing Practice Certified Facility

General Statements

Please recycle Order online: www.BiotechNutrtions.com

Formula

Ellagic acid from black raspberry & extract

FDA Statement of Identity

Dietary Supplement

See for yourself

Ellagic Acid by Biotech Nutritions label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Ellagic Acid by Biotech Nutritions

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Proprietary Blend

1120 mg per serving

Other (inactive) ingredients: Vegetable Capsule. These complete the product’s ingredient list but are not active constituents.

Interaction report

Ellagic Acid by Biotech Nutritions Drug Interactions

Want to check YOUR meds against Ellagic Acid?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
208Drugs
208 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Ellagic Acid with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Red Raspberry extract2 drug types · 135 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, taking red raspberry leaf with anticoagulant/antiplatelet drugs might increase the risk of bleeding.
In vitro research suggests that red raspberry leaf extract has antiplatelet activity and enhances the in vitro effects of the antiplatelet medication cangrelor. This interaction has not been reported in humans.

Likelihood Possible Evidence D
Insulin

Red raspberry leaf might reduce glucose levels in patients being treated with insulin.
In one case report, a 38-year-old patient with gestational diabetes, whose blood glucose was being controlled with medical nutrition therapy and insulin, developed hypoglycemia after consuming two servings of raspberry leaf tea daily for 3 days beginning at 32 weeks' gestation. The patient required an insulin dose reduction. The hypoglycemia was considered to be probably related to use of red raspberry leaf tea.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Ellagic Acid, from the product label.

Biotech Nutritions

See all Biotech Nutritions products
Name
Biotech Nutritions
Street Address
P.O. Box 865
City
Novi
State
MI
ZipCode
48376
Phone Number
888-662-7001
Web Address
www.BiotechNutritions.com
Pharmacist Counseling Corner

Ellagic Acid by Biotech Nutritions: Common Questions

Does Ellagic Acid by Biotech Nutritions interact with any medications?
Yes. Based on its ingredients, Ellagic Acid has a known interaction with 208 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Ellagic Acid contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does ellagic acid actually help with diabetes?
The evidence isn't established yet. While some research shows ellagic acid may lower blood sugar levels, we don't have enough reliable data to say whether it works for managing diabetes itself. That's why it's rated as insufficient evidence for diabetes.
Can I take this if I'm pregnant or breastfeeding?
Black raspberry is likely safe during pregnancy and lactation when eaten as food, but we don't have safety data for this concentrated supplement or for ellagic acid at supplement doses. Talk with your doctor or pharmacist — they can help you figure out whether it's right for you right now.
What side effects has this caused in trials?
In one clinical trial, a combination product containing ellagic acid and another herb caused nausea and diarrhea in a few participants out of 30. It's not clear whether ellagic acid, the other herb, or the combination was responsible. Otherwise, adverse effects aren't well documented.
Is this product safe in general?
Ellagic acid from food sources is considered safe, but concentrated supplement doses haven't been well studied in humans — the product facts advise caution. Black raspberry is generally well tolerated as a food or supplement, though concentrated extracts have less safety data than the whole berry.
Why are the effectiveness ratings all 'insufficient evidence'?
These ingredients have been researched, but the studies so far haven't been large enough or strong enough to prove they work for any specific condition. That doesn't mean they don't work — it means we need better evidence to know for sure.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Ellagic Acid is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Ellagic Acid label
Sources

Sources & How We Checked

Ellagic Acid's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 21 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Ellagic Acid 9 references
  1. Ertam I, Mutlu B, Unal I, Alper S, Kivçak B, Ozer O. Efficiency of ellagic acid and arbutin in melasma: a randomized, prospective, open-label study. J Dermatol. 2008;35(9):570-4. PubMed
  2. Dahl A, Yatskayer M, Raab S, Oresajo C. Tolerance and efficacy of a product containing ellagic and salicylic acids in reducing hyperpigmentation and dark spots in comparison with 4% hydroquinone. J Drugs Dermatol. 2013;12(1):52-8.
  3. Falsaperla M, Morgia G, Tartarone A, Ardito R, Romano G. Support ellagic acid therapy in patients with hormone refractory prostate cancer (HRPC) on standard chemotherapy using vinorelbine and estramustine phosphate. Eur Urol. 2005;47(4):449-54 PubMed
  4. Le Donne M, Lentini M, Alibrandi A, et al. Antiviral activity of Ellagic acid and Annona Muricata in cervical HPV related pre-neoplastic lesions: A randomized trial. J Funct Food 2017;35:549-54. DOI
  5. Liu Y, Yu S, Wang F, et al. Chronic administration of ellagic acid improved the cognition in middle-aged overweight men. Appl Physiol Nutr Metab. 2018;43(3):266-73. PubMed
  6. Serretta V, Berardinis E, Simonato A, et al. A prospective observational study on oral administration of Ellagic Acid and Annona Muricata in patients affected by non-muscle invasive bladder cancer not undergoing maintenance after 6-week intravesical proph
  7. Ghadimi M, Foroughi F, Hashemipour S, et al. Randomized double-blind clinical trial examining the Ellagic acid effects on glycemic status, insulin resistance, antioxidant, and inflammatory factors in patients with type 2 diabetes. Phytother Res 2021;35(2) PubMed
  8. Kazemi M, Lalooha F, Nooshabadi MR, Dashti F, Kavianpour M, Haghighian HK. Randomized double blind clinical trial evaluating the Ellagic acid effects on insulin resistance, oxidative stress and sex hormones levels in women with polycystic ovarian syndrome PubMed
  9. Ghadimi M, Foroughi F, Hashemipour S, et al. Decreased insulin resistance in diabetic patients by influencing Sirtuin1 and Fetuin-A following supplementation with ellagic acid: a randomized controlled trial. Diabetol Metab Syndr 2021;13(1):16. PubMed

See these in context on the Ellagic Acid monograph →

Black Raspberry 4 references
  1. An JH, Kim DL, Lee TB, et al. Effect of Rubus Occidentalis Extract on Metabolic Parameters in Subjects with Prediabetes: A Proof-of-concept, Randomized, Double-blind, Placebo-controlled Clinical Trial. Phytother Res. 2016;30(10):1634-40.
  2. Jeong HS, Hong SJ, Cho JY, et al. Effects of Rubus occidentalis extract on blood pressure in patients with prehypertension: Randomized, double-blinded, placebo-controlled clinical trial. Nutrition. 2016;32(4):461-7. PubMed
  3. Mallery SR, Tong M, Shumway BS, et al. Topical application of a mucoadhesive freeze-dried black raspberry gel induces clinical and histologic regression and reduces loss of heterozygosity events in premalignant oral intraepithelial lesions: results from a
  4. Jeong HS, Kim S, Hong SJ, et al. Black Raspberry Extract Increased Circulating Endothelial Progenitor Cells and Improved Arterial Stiffness in Patients with Metabolic Syndrome: A Randomized Controlled Trial. J Med Food. 2016;19(4):346-52. PubMed

See these in context on the Black Raspberry monograph →

Red Raspberry 8 references
  1. Eagon PK, Elm MS, Hunter DS, et al. Medicinal herbs: modulation of estrogen action. Era of Hope Mtg, Dept Defense; Breast Cancer Res Prog, Atlanta, GA 2000;Jun 8-11.
  2. Parsons M, Simpson M, Ponton T. Raspberry leaf and its effects on labour: safety and efficacy. Aust Coll Midwives Inc J 1999;12:20-5.
  3. Simpson M, Parsons M, Greenwood J, Wade K. Raspberry leaf in pregnancy: its safety and efficacy in labor. J Midwifery Womens Health 2001;46:51-9.. PubMed
  4. Mullen W, McGinn J, Lean ME, et al. Ellagitannins, flavonoids, and other phenolics in red raspberries and their contribution to antioxidant capacity and vasorelaxation properties. J Agric Food Chem 2002;50:5191-6.. PubMed
  5. Sherson, D., Andersen, B., Hansen, I., and Kjoller, H. Occupational asthma due to freeze-dried raspberry. Ann Allergy Asthma Immunol. 2003;90(6):660-663. PubMed
  6. Cheang KI, Nguyen TT, Karjane NW, Salley KE. Raspberry Leaf and Hypoglycemia in Gestational Diabetes Mellitus. Obstet Gynecol. 2016;128(6):1421-4. PubMed
  7. Dudzinska D, Bednarska K, Boncler M, Luzak B, Watala C. The influence of Rubus idaeus and Rubus caesius leaf extracts on platelet aggregation in whole blood. Cross-talk of platelets and neutrophils. Platelets. 2016;27(5):433-9.
  8. Henrotin Y, Cozannet RL, Fança-Berthon P, et al. Rubus idaeus extract improves symptoms in knee osteoarthritis patients: results from a phase II double-blind randomized controlled trial. BMC Musculoskelet Disord 2022;23(1):650. PubMed

See these in context on the Red Raspberry monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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