Interactions on record — worth a quick check against your medications. Based on 5 of 12 ingredients. Check your meds →
Dietary supplement

Estrogenex Depot 625 mg Ingredients & Drug Interactions

by Hi-Tech Pharmaceuticals

Estrogenex Depot 625 mg label
See full label image
Tablet Or Pill Category: Botanical With Nutrients
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Estrogenex Depot 625 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Estrogenex Depot 625 mg is a dietary supplement by Hi-Tech Pharmaceuticals with 12 active ingredients. Its ingredients are commonly taken for estrogen and hormone balance support, breast and cervical health, prostate health.Based on those ingredients, 452 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Indole-3-Carbinol, Stinging Nettle extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Estrogenex Depot 625 mg by Hi-Tech Pharmaceuticals

Ask about any prescription or over-the-counter medication and we check it for interactions with Estrogenex Depot 625 mg by Hi-Tech Pharmaceuticals — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Estrogenex Depot 625 mg by Hi-Tech Pharmaceuticals

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 12 active ingredients.
  • “Proprietary Blend” is a proprietary blend — the label gives one combined amount (625 mg) without saying how much of each component you get.

Estrogenex Depot contains 12 active ingredients in a proprietary blend, though the exact amounts of each aren't broken out individually. The main players we can identify are indole-3-carbinol (a compound from cruciferous vegetables), epiandrosterone (a hormone precursor), beta-sitosterol (a plant sterol), stinging nettle extract, muira puama extract, and several other botanical or synthetic compounds.

The product also contains inactive ingredients like microcrystalline cellulose (a binder), magnesium stearate and stearic acid (flow agents), and colorants including FD&C dyes, plus dextrose and silica. These inactive ingredients are standard tablet fillers and don't change how the active ingredients work.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use.

Why this rating?
  • The label markets this product for: supports optimal free testosterone activity.
  • We looked for evidence on: Athletic performance, Erectile dysfunction (ED), Muscle strength, Sexual arousal, Sexual dysfunction, Lean body mass — and 2 related terms.
  • The closest evidence on file: Muira Puama is rated "Insufficient Reliable Evidence To Rate" for Sexual dysfunction (Natural Medicines).
  • Also on file: Muira Puama is rated "Insufficient Reliable Evidence To Rate" for Erectile dysfunction (ED).
  • Also on file: Epiandrosterone is rated "Insufficient Reliable Evidence To Rate" for Athletic performance, Erectile dysfunction (ED), Muscle strength, Sexual arousal.

The evidence for what this product actually does is thin. Indole-3-carbinol has insufficient evidence to rate for breast cancer, colorectal cancer, cervical dysplasia, liver disease, and fibromyalgia—meaning we don't have reliable data showing it works for those uses.

Beta-sitosterol is likely effective for benign prostate enlargement and possibly effective for familial high cholesterol and coronary heart disease, but that's just one ingredient here and the blend as a whole isn't studied for its claimed purpose. Stinging nettle is possibly effective for diabetes and has insufficient evidence for hay fever, anemia, asthma, prostate health, and gingivitis.

Epiandrosterone and muira puama both have insufficient evidence for their claimed uses—sexual function, muscle, athletic performance, and obesity. The bottom line: we don't have solid evidence that this specific product works as marketed.

The evidence, ingredient by ingredient Indole-3-carbinol Epiandrosterone Beta-sitosterol Stinging Nettle Muira Puama

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 3 of the 5 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 5 of 5.
  • General safety write-ups exist for 5 of 5.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Indole-3-carbinol is generally well tolerated when taken orally, though the most common side effects are diarrhea, nausea, rash, tremor, unsteadiness, and imbalance—especially at higher doses. One case involved a man taking 400 mg twice daily who developed tremor and imbalance after 10 days; cutting the dose in half resolved it.

Beta-sitosterol is generally well tolerated and may cause constipation, diarrhea, gas, indigestion, nausea, or reduced appetite; it can also worsen acne. Stinging nettle is generally well tolerated and most commonly causes constipation or diarrhea, though a rare case of liver injury has been reported.

Epiandrosterone is a hormone-related supplement with limited safety data and real potential for androgenic (male hormone–like) side effects. None of these ingredients should be used during pregnancy, and none should be used while breastfeeding except that pregnancy and lactation data are not on file for beta-sitosterol and stinging nettle—talk with your doctor or pharmacist about those two.

Side effects, ingredient by ingredient Indole-3-carbinol Epiandrosterone Beta-sitosterol Stinging Nettle Muira Puama

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 2 of the 5 matched ingredients can interact with medications — Stinging Nettle, Indole-3-carbinol.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications; lithium.
  • For scale: 452 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking Estrogenex Depot, check with your pharmacist if you take blood thinners or antiplatelet drugs (like warfarin or aspirin), estrogen therapy, drugs for diabetes, diuretics (water pills), lithium, or any medications your liver metabolizes through CYP1A2. These are Moderate severity interactions.

We could not check several ingredients in this product for interactions, so running your exact medications through our tool on this page is important.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

This is a hormone-related supplement designed to alter estrogen metabolism, so it's not for everyone and carries real risks. If you take any blood thinners, estrogen therapy, blood sugar medications, diuretics, lithium, or medications your liver breaks down, you need to check with us or your pharmacist before starting.

Even if you don't take those, the side effects—especially diarrhea and imbalance at higher doses—are worth knowing about. Talk to your pharmacist about whether this product makes sense for you.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 5 of 12 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Mar 25, 2014.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Estrogenex Depot 625 mg, straight from the product label.

Brand Hi-Tech Pharmaceuticals
Net contents 90 ct
Market status On market
Date entered into DSLD Mar 25, 2014
DSLD ID 31275
Product type Botanical With Nutrients
Supplement form Tablet Or Pill
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Estrogenex Depot 625 mg by Hi-Tech Pharmaceuticals, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Tablet(s)
Maximum serving Sizes:
1 Tablet(s)
Servings per container
90
IngredientAmount% DV
Proprietary Blend625 mg--
Indole-3-Carbinol0 NP--
Epiandrosterone0 NP--
Beta-Sitosterol0 NP--
Naringen0 NP--
Brassaiopsis glomerulata extract0 NP--
N-Benzoyl-L-Phenylalanine Methyl Ester0 NP--
7, 8-Benzoflavone0 NP--
8-Bromo-7-Methoxychrysin0 NP--
9-Hydroxy-Alpha-Naphthoflavone0 NP--
Coumestrol Dimethyl Ether0 NP--
Stinging Nettle extract0 NP--
Muira Puama 20:1 extract0 NP--

Other ingredients: Dextrose, Microcrystalline Cellulose, Stearic Acid, Magnesium Stearate, Sodium Starch Glycolate, Starch, Triacetin, Titanium Dioxide, Silica, FD&C Red #3, FD&C Yellow #6

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Directions: Take 1 tablet three times daily. Best taken near mealtime.

Precautions

Do not exceed 6 tablets daily.

WARNING: NOT FOR USE BY INDIVIDUALS UNDER THE AGE OF 18 YEARS.

DO NOT USE IF PREGNANT OR NURSING.

General Statements

(WARNINGS/INFORMATION CONTINUED ON BACK OF LABEL)

STRONGEST AROMATASE INHIBITOR ANABOLIC LEAN MASS CATALYST SUPPORTS OPTIMAL FREE TESTOSTERONE ACTIVITY

Seals/Symbols

HTP HI-TECH PHARMACEUTICALS

FDA Statement of Identity

DIETARY SUPPLEMENT

FDA Disclaimer Statement

THESE STATEMENTS HAVE NOT BEEN EVALUATED BY THE FOOD AND DRUG ADMINISTRATION. THIS PRODUCT IS NOT INTENDED TO DIAGNOSE, TREAT, CURE OR PREVENT ANY DISEASE.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Estrogenex Depot 625 mg by Hi-Tech Pharmaceuticals label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Estrogenex Depot 625 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Estrogenex Depot 625 mg by Hi-Tech Pharmaceuticals

These are the 12 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Tablet(s) Dosage formTablet Or Pill Servings per container90 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Proprietary Blend

625 mg per serving

Other (inactive) ingredients: Dextrose, Microcrystalline Cellulose, Stearic Acid, Magnesium Stearate, Sodium Starch Glycolate, Starch, Triacetin, Titanium Dioxide, Silica, FD&C Red #3, FD&C Yellow #6. These complete the product’s ingredient list but are not active constituents.

Interaction report

Estrogenex Depot 625 mg by Hi-Tech Pharmaceuticals Drug Interactions

Want to check YOUR meds against Estrogenex Depot 625 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
452Drugs
452 Moderate

Ingredients driving the most interactions

Indole-3-Carbinol 294
Stinging Nettle extract 164

Individual Drug Interactions

The ingredients in Estrogenex Depot 625 mg interact with 452 drugs. Click any drug to see the details.

2 of the 12 ingredients in Estrogenex Depot 625 mg interact with drugs. Each result below shows which ingredient is responsible. Indole-3-Carbinol Stinging Nettle extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Estrogenex Depot 625 mg with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Indole-3-Carbinol3 drug types · 294 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, indole-3-carbinol might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
In vitro research shows that indole-3-carbinol inhibits platelet aggregation.

Likelihood Possible Evidence D
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, indole-3-carbinol might increase the metabolism of CYP1A2 substrates and lower serum concentrations.
Animal research shows that indole-3-carbinol induces CYP1A2 enzymes.

Likelihood Possible Evidence D
Estrogens

Indole-3-carbinol might interfere with the effects of estrogen therapy.
Preliminary clinical and in vitro evidence shows that indole-3-carbinol has antiestrogenic activity.

Likelihood Possible Evidence D
Indole-3-Carbinol full monograph & interactions

Stinging Nettle extract4 drug types · 164 drugs

Antidiabetes Drugs

Theoretically, stinging nettle might have additive effects with antidiabetes drugs.
Clinical research shows that stinging nettle might decrease blood glucose levels in patients with diabetes.

Likelihood Possible Evidence B
Diuretic Drugs

Theoretically, combining stinging nettle with diuretic drugs may have additive effects.
Animal research suggests that the above ground parts and roots of stinging nettle may have a diuretic effect.

Likelihood Possible Evidence D
Lithium

Theoretically, stinging nettle might reduce excretion and increase levels of lithium.
Animal research suggests that stinging nettle has diuretic and natriuretic properties, which could alter the excretion of lithium. The dose of lithium might need to be decreased.

Likelihood Possible Evidence D
Warfarin (Coumadin)

There is some concern that stinging nettle might decrease the effects of anticoagulant drugs such as warfarin.
Stinging nettle contains a significant amount of vitamin K. When taken in large quantities, this might interfere with the activity of warfarin.

Likelihood Possible Evidence D
Stinging Nettle extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Estrogenex Depot 625 mg, from the product label.

Hi-Tech Pharmaceuticals

See all Hi-Tech Pharmaceuticals products
Name
Hi-Tech Pharmaceuticals, Inc.
Street Address
6015-B Unity Drive
City
Norcross
State
GA
ZipCode
30071
Phone Number
1.888.855.7919
Web Address
www.hitechpharma.com
Pharmacist Counseling Corner

Estrogenex Depot 625 mg by Hi-Tech Pharmaceuticals: Common Questions

Does Estrogenex Depot 625 mg by Hi-Tech Pharmaceuticals interact with any medications?
Yes. Based on its ingredients, Estrogenex Depot 625 mg has a known interaction with 452 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Estrogenex Depot 625 mg contains 12 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm on birth control or hormone therapy?
No—indole-3-carbinol in this product has antiestrogenic activity, meaning it may work against estrogen and interfere with how estrogen therapy works. Talk to your doctor before combining this with any hormone medication.
What's the most common side effect I should watch for?
Diarrhea is the most frequently reported side effect from indole-3-carbinol. You may also notice nausea, rash, or at higher doses, unsteadiness and tremor. If you develop imbalance or tremor, tell your pharmacist right away.
Is it safe to take while pregnant or breastfeeding?
No. Indole-3-carbinol, epiandrosterone, and the other hormone-related ingredients should be avoided during pregnancy and breastfeeding because there isn't enough safety data and these are hormone-altering compounds.
Does this actually work for what it claims?
The evidence isn't there yet. Indole-3-carbinol has insufficient evidence for cancer prevention, liver disease, and other claims. Beta-sitosterol does have some evidence for prostate and cholesterol support, but the blend as a whole hasn't been studied, so we can't say whether it works.
What is epiandrosterone, and is it safe?
Epiandrosterone is a hormone-related supplement (a steroid precursor) with very limited safety data and real potential for androgenic—male hormone–like—side effects. It's not recommended during pregnancy or breastfeeding.
What's in the 'proprietary blend,' and why aren't the amounts listed?
The blend contains multiple active ingredients including indole-3-carbinol, epiandrosterone, beta-sitosterol, and several others. Manufacturers often keep the exact amounts proprietary to protect their formulas, which means you don't know how much of each ingredient you're actually getting.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Estrogenex Depot 625 mg is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Estrogenex Depot 625 mg label
Go deeper

The Full Monographs Behind Estrogenex Depot 625 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Indole-3-carbinol

Interacts with 294 drugs

Indole-3-carbinol (I3C) is a compound formed when you eat cruciferous vegetables like broccoli and cabbage, and it is sold as a supplement mainly for hormone-related and cell-protective effe...

Read the full Indole-3-carbinol monograph → Herb & supplement monograph

Epiandrosterone

Epiandrosterone is a steroid-related compound (a metabolite of DHEA) sold as a 'prohormone' supplement, mostly for muscle building and athletic performance. There is very little high-quality...

Read the full Epiandrosterone monograph → Herb & supplement monograph

Beta-sitosterol

Beta-sitosterol is a plant sterol that may modestly lower LDL ('bad') cholesterol and may help ease urinary symptoms from an enlarged prostate. Evidence is moderate for these uses and weaker...

Read the full Beta-sitosterol monograph → Herb & supplement monograph

Stinging Nettle

Interacts with 164 drugs

Stinging nettle is a common plant used as food and in traditional medicine, most often for prostate symptoms, allergies, and joint pain. The evidence is mixed and mostly preliminary, so it i...

Read the full Stinging Nettle monograph → Herb & supplement monograph

Muira Puama

Muira puama is a Brazilian plant traditionally used as an aphrodisiac and general tonic, often nicknamed 'potency wood.' Human research is very limited, so its benefits are not well proven,...

Read the full Muira Puama monograph →
Sources

Sources & How We Checked

Estrogenex Depot 625 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 42 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Indole-3-carbinol 9 references
  1. Rosen CA, Woodson GE, Thompson JW, et al. Preliminary results of the use of indole-3-carbinol for recurrent respiratory papillomatosis. Otolaryngol Head Neck Surg 1998;118:810-5. PubMed
  2. Bell MC, Crowley-Nowick P, Bradlow HL, et al. Placebo-controlled trial of indole-3-carbinol in the treatment of CIN. Gynecol Oncol 2000;78:123-9. PubMed
  3. He YH, Friesen MD, Ruch RJ, Schut HA. Indole-3-carbinol as a chemopreventive agent in 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) carcinogenesis: inhibition of PhIP-DNA adduct formation, acceleration of PhIP metabolism, and induction of cytoch
  4. Kim, Y. S. and Milner, J. A. Targets for indole-3-carbinol in cancer prevention. J.Nutr.Biochem. 2005;16(2):65-73. PubMed
  5. Anon. Indole-3-carbinol. Monograph. Alternative Medicine Review 2005;10(4):337-42.
  6. McAlindon TE, Gulin J, Chen T, et al. Indole-3-carbinol in women with SLE: effect on estrogen metabolism and disease activity. Lupus 2001;10:779-83. PubMed
  7. Reed GA, Peterson KS, Smith HJ, et al. A phase I study of indole-3-carbinol in women: tolerability and effects. Cancer Epidemiol Biomarkers Prev 2005;14:1953-60. PubMed
  8. Bradlow HL, Michnovicz JJ, Halper M, et al. Long-term responses of women to indole-3-carbinol or a high fiber diet. Cancer Epidemiol Biomarkers Prev 1994;3:591-5.
  9. Paliwal P, Chauhan G, Gautam D, Dash D, Patne SCU, Krishnamurthy S. Indole-3-carbinol improves neurobehavioral symptoms in a cerebral ischemic stroke model. Naunyn Schmiedebergs Arch Pharmacol. 2018;391(6):613-625. PubMed

See these in context on the Indole-3-carbinol monograph →

Epiandrosterone 1 reference
  1. Joseph JF, Parr MK. Synthetic androgens as designer supplements. Curr Neuropharmacol. 2015;13(1):89-100. PubMed

See these in context on the Epiandrosterone monograph →

Beta-sitosterol 7 references
  1. Berges RR, Windeler J, Trampisch HJ, et al. Randomised, placebo-controlled, double-blind clinical trial of beta-sitosterol in patients with benign prostatic hyperplasia. Beta-sitosterol Study Group. Lancet 1995;345:1529-32.
  2. Klippel KF, Hiltl DM, Schipp B. A multicentric, placebo-controlled, double-blind clinical trial of beta-sitosterol (phytosterol) for the treatment of benign prostatic hyperplasia. Br J Urol 1997;80:427-32.
  3. Wilt TJ, MacDonald R, Ishani A. beta-sitosterol for the treatment of benign prostatic hyperplasia: a systematic review. BJU Int 1999;83:976-83. PubMed
  4. Oster P, Schlierf G, Heuck CC, et al. [Sitosterol in familial hyperlipoproteinemia type II. A randomized, double-blind, cross-over study]. Dtsch Med Wochenschr 1976;101:1308-11.
  5. Becker M, Staab D, Von Bergman K. Long-term treatment of severe familial hypercholesterolemia in children: effect of sitosterol and bezafibrate. Pediatrics 1992;89:138-42. DOI
  6. Prager N, Bickett K, French N, Marcovici G. A randomized, double-blind, placebo-controlled trial to determine the effectiveness of botanically derived inhibitors of 5-alpha-reductase in the treatment of androgenetic alopecia. J Altern Complement Med 2002
  7. Lorenze A, Hsueh W, Nasr J. Beta-sitosterol-induced acute pancreatitis: A case report and review of the literature. Cureus. 2020;12(3):e7407. PubMed

See these in context on the Beta-sitosterol monograph →

Stinging Nettle 23 references
  1. Monographs on the medicinal uses of plant drugs. Exeter, UK: European Scientific Co-op Phytother, 1997.
  2. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
  3. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
  4. Schulz V, Hansel R, Tyler VE. Rational Phytotherapy: A Physician's Guide to Herbal Medicine. Terry C. Telger, transl. 3rd ed. Berlin, GER: Springer, 1998.
  5. Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics. 2nd ed. New York, NY: John Wiley & Sons, 1996.
  6. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  7. Mittman P. Randomized, double-blind study of freeze-dried Urtica dioica in the treatment of allergic rhinitis. Planta Med 1990;56:44-7.
  8. Vontobel HP, Herzog R, Rutishauser G, Kres H. [Results of a double-blind study on the effectiveness of ERU (extractum radicis Urticae) capsules in conservative treatment of benign prostatic hyperplasia]. (Abstract). Urologe A 1985;24:49-51.
  9. Randall C, Randall H, Dobbs F, et al. Randomized controlled trial of nettle sting for treatment of base-of-thumb pain. J R Soc Med 2000;93:305-9. PubMed
  10. Caliskaner Z, Karaayvaz M, Ozturk S. Misuse of a herb: stinging nettle (Urtica urens) induced severe tongue oedema. Complement Ther Med 2004;12:57-8. PubMed
  11. Krzeski, T., Kazon, M., Borkowski, A., Witeska, A., and Kuczera, J. Combined extracts of Urtica dioica and Pygeum africanum in the treatment of benign prostatic hyperplasia: double-blind comparison of two doses. Clin Ther 1993;15(6):1011-1020.
  12. Randall, C., Meethan, K., Randall, H., and Dobbs, F. Nettle sting of Urtica dioica for joint pain--an exploratory study of this complementary therapy. Complement Ther Med 1999;7(3):126-131. PubMed
  13. Tahri, A., Yamani, S., Legssyer, A., Aziz, M., Mekhfi, H., Bnouham, M., and Ziyyat, A. Acute diuretic, natriuretic and hypotensive effects of a continuous perfusion of aqueous extract of Urtica dioica in the rat. J Ethnopharmacol 2000;73(1-2):95-100. PubMed
  14. Sahin, M., Yilmaz, H., Gursoy, A., Demirel, A. N., Tutuncu, N. B., and Guvener, N. D. Gynaecomastia in a man and hyperoestrogenism in a woman due to ingestion of nettle (Urtica dioica). N.Z.Med.J. 2007;120(1265):U2803.
  15. Randall, C., Dickens, A., White, A., Sanders, H., Fox, M., and Campbell, J. Nettle sting for chronic knee pain: a randomised controlled pilot study. Complement Ther.Med. 2008;16(2):66-72. PubMed
  16. Rayburn, K., Fleischbein, E., Song, J., Allen, B., Kundert, M., Leiter, C., and Bush, T. Stinging nettle cream for osteoarthritis. Altern.Ther.Health Med. 2009;15(4):60-61.
  17. Oliver, F., Amon, E. U., Breathnach, A., Francis, D. M., Sarathchandra, P., Black, A. K., and Greaves, M. W. Contact urticaria due to the common stinging nettle (Urtica dioica)-- histological, ultrastructural and pharmacological studies. Clin Exp Dermato PubMed
  18. Kulze, A. and Greaves, M. Contact urticaria caused by stinging nettles. Br.J Dermatol. 1988;119(2):269-270. PubMed
  19. Patten G. Medicinal plant review: Urtica. Aust J Med Herbalism 1993;5(1):5-13.
  20. Maor D, Little M. Skin contact with a stinging tree requiring intensive care unit admission. Contact Dermatitis. 2017 Nov;77(5):335-37. PubMed
  21. Easton L, Vaid S, Nagel AK, Venci JV, Fortuna RJ. Stinging Nettle (Urtica dioica): An Unusual Case of Galactorrhea. Am J Case Rep 2021;22:e933999. PubMed
  22. Niazi B, Ahmed K, Ahmed M, Ali S, Song K, Elias S. Drug-Induced Liver Injury from Herbal Liver Detoxification Tea. Case Rep Gastroenterol 2022;16(3):612-617. PubMed
  23. Nnamani I, Tolu-Akinnawo O, Dufera RR, Akintunde A, Maliakkal B. Tinospora cordifolia (Guduchi/Giloy)-Induced Liver Injury: A Case Review. Cureus 2023;15(5):e39793. PubMed

See these in context on the Stinging Nettle monograph →

Muira Puama 2 references
  1. Waynberg, J. and Brewer, S. Effects of Herbal vX on libido and sexual activity in premenopausal and postmenopausal women. Adv Ther 2000;17(5):255-262. PubMed
  2. Nguyen S, Rajfer J, Shaheen M. Safety and efficacy of daily Revactin in men with erectile dysfunction: a 3-month pilot study. Transl Androl Urol. 2018;7(2):266-73. PubMed

See these in context on the Muira Puama monograph →

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