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Dietary supplement

European Mistletoe Young Shoot Ingredients & Drug Interactions

by Genestra Brands

Liquid Category: Botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

European Mistletoe Young Shoot is a dietary supplement by Genestra Brands with 1 active ingredient. Its ingredients are commonly taken for cancer supportive care, immune support, high blood pressure.Based on those ingredients, 293 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are European Mistletoe (Viscum album) young shoot extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of European Mistletoe Young Shoot by Genestra Brands

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: European mistletoe young shoot extract. It's prepared as a liquid in ethanol and glycerin with purified water.

Does it work?

Leans against
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Leans against

The strongest graded evidence we hold for the stated purpose leans against a benefit.

Why this rating?
  • The label markets this product for: European Mistletoe for immune and cancer support.
  • We looked for evidence on: Bladder cancer, Breast cancer, Cancer-related fatigue, Chemotherapy-induced diarrhea, Colorectal cancer, Gastric cancer — and 4 related terms.
  • The closest evidence on file: European Mistletoe is rated "Possibly Ineffective" for Head and neck cancer (Natural Medicines).
  • Also on file: European Mistletoe is rated "Insufficient Reliable Evidence To Rate" for Bladder cancer, Breast cancer, Gastric cancer, Chemotherapy-induced diarrhea, and more.

The evidence for this product doesn't establish that it works for the conditions studied. For melanoma and head and neck cancer, research shows it's possibly ineffective.

For breast cancer, gastric cancer, and chemotherapy-related diarrhea, the available evidence is too limited to say either way.

The evidence, ingredient by ingredient European Mistletoe

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

When taken by mouth in small amounts, European mistletoe is generally well tolerated, though a full safety review hasn't been completed. At high doses, diarrhea, intestinal cramps, and vomiting may occur.

Raw mistletoe is toxic and should never be swallowed — only use standardized products, ideally under medical supervision. The safety data advises against this product during pregnancy and while breastfeeding because of potential toxicity and insufficient safety information.

Side effects, ingredient by ingredient European Mistletoe

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — European Mistletoe.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: immunosuppressants / transplant drugs.
  • For scale: 293 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check your blood pressure medications (antihypertensive drugs) and any immune-suppressing medications (immunosuppressants) with your pharmacist before taking this product — both carry Moderate interaction concerns.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with graded evidence leaning against its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This product is a single-ingredient extract intended for specific medical conditions, but evidence of effectiveness is limited or absent. If you take blood pressure medications or immunosuppressants, talk with your pharmacist before starting it.

Pregnancy and breastfeeding are not appropriate times to use it. Always use under professional guidance.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Oct 22, 2016.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about European Mistletoe Young Shoot, straight from the product label.

Brand Genestra Brands
Barcode (UPC) 88319612780
Net contents 0.5 fl. Oz.; 15 mL
Market status Off market
Date entered into DSLD Oct 22, 2016
DSLD ID 65578
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other
Intended target group(s) Children 4 or More Years of Age, Vegan, Vegetarian, Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for European Mistletoe Young Shoot by Genestra Brands, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
0.28 mL
Maximum serving Sizes:
0.28 mL
Servings per container
53
UPC/BARCODE
88319612780
IngredientAmount% DV
European Mistletoe (Viscum album) young shoot extract0.28 mL--

Other ingredients: purified Water, Ethanol, Glycerin

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Recommended Dose: Adults and Children (over 12 years): Take 10 drops once daily, or as recommended by your healthcare practitioner. Invert bottle to 45(0) and shake lightly allowing drops to fall directly into mouth or in 1/4 oz. of water.

Precautions

For risk information, see outer box. Do not use if seal is missing or broken.

Risk Information: If you are pregnant or breastfeeding, do not use, unless directed by your healthcare practitioner.

If symptoms persist or worsen, consult your healthcare practitioner.

Quality Assurance: Safety-sealed for your protection and for product freshness. Do not use if inner seal is missing or broken.

General

977

FDA Statement of Identity

Herbal Supplement

General Statements

Phyto-Gen

Formulation

Guaranteed to contain no added starch, yeast, gluten, corn, soy, sodium, sugar, artificial coloring or flavoring, antimicrobial preservatives, dairy or animal products.

Ideal for vegans.

Storage

Store in a cool, dry place.

See for yourself

European Mistletoe Young Shoot by Genestra Brands label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in European Mistletoe Young Shoot by Genestra Brands

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size0.28 mL Dosage formLiquid Servings per container53 Amounts shown are per serving.

0.28 mL per serving

European mistletoe is a parasitic plant most studied as an injectable extract used alongside conventional cancer care in some European countries, main...

European Mistletoe (Viscum album) young shoot extract monograph & interactions

Other (inactive) ingredients: Purified Water, Ethanol, Glycerin. These complete the product’s ingredient list but are not active constituents.

Interaction report

European Mistletoe Young Shoot by Genestra Brands Drug Interactions

Want to check YOUR meds against European Mistletoe Young Shoot?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
293Drugs
293 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in European Mistletoe Young Shoot with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

European Mistletoe (Viscum album) young shoot extract2 drug types · 293 drugs

Antihypertensive Drugs

Theoretically, European mistletoe might increase the risk of hypotension when taken with antihypertensive drugs.
Animal research suggests that European mistletoe extracts have hypotensive effects.

Likelihood Possible Evidence D
Immunosuppressants

Theoretically, European mistletoe might decrease the effectiveness of immunosuppressants.
Clinical and in vitro studies suggest that European mistletoe might have immunostimulant effects.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for European Mistletoe Young Shoot, from the product label.

Genestra Brands

Name
Seroyal USA
City
Wood Dale
State
Illinois
ZipCode
60191
Phone Number
1-888-737-6925
Pharmacist Counseling Corner

European Mistletoe Young Shoot by Genestra Brands: Common Questions

Does European Mistletoe Young Shoot by Genestra Brands interact with any medications?
Yes. Based on its ingredients, European Mistletoe Young Shoot has a known interaction with 293 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
European Mistletoe Young Shoot contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is raw mistletoe the same as this extract?
No. Raw mistletoe is toxic if you swallow it. This is a standardized extract, which is much safer — but it should still be used under medical supervision, not on your own.
Can I take this while I'm pregnant?
No. The safety data advises against it because of potential toxicity and the lack of safety information in pregnancy. Talk with your doctor about what's appropriate for you.
What are the most common side effects?
When taken by mouth in small amounts, it's generally well tolerated. At higher doses, diarrhea, intestinal cramps, and vomiting may happen. If you experience any of these, stop and talk to your pharmacist.
Does this product work for cancer?
The evidence doesn't establish that it works. For melanoma and head and neck cancer, research shows it's possibly ineffective. For breast and gastric cancers and chemotherapy-related diarrhea, there's not enough reliable evidence to say.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if European Mistletoe Young Shoot is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

European Mistletoe Young Shoot label
Sources

Sources & How We Checked

European Mistletoe Young Shoot's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 35 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

European Mistletoe 35 references
  1. Wichtl MW. Herbal Drugs and Phytopharmaceuticals. Ed. N.M. Bisset. Stuttgart: Medpharm GmbH Scientific Publishers, 1994.
  2. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
  3. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  4. Harvey J, Colin-Jones DG. Mistletoe hepatitis. Br Med J (Clin Res Ed) 1981;282:186-7.
  5. Natl Cancer Inst. Mistletoe (PDQ). CancerNet. www.cancernet.nci.nih.gov/cam/mistletoe.htm#7 (Accessed 30 March 2001).
  6. Kaegi E. Unconventional therapies for cancer: 3. Iscador. Task Force on Alternative Therapies of the Canadian Breast Cancer Research Initiative. CMAJ 1998;158:1157-9.
  7. Grossarth-Matichek R, Kiene H, Baumgartner SM, Ziegler R. Use of Iscador, an extract of European mistletoe (Viscum album), in cancer treatment: prospective nonrandomized and randomized matched-pair studies nested within a cohort study. Altern Ther Health
  8. Huber R, Barth H, Schmitt-Graff A, Klein R. Hypereosinophilia induced by high-dose intratumoral and peritumoral mistletoe application to a patient with pancreatic carcinoma. J Altern Complement Med 2000;6:305-10. PubMed
  9. Timoshenko AV, Cherenkevich SN, Gabius HJ. Viscum album agglutinin-induced aggregation of blood cells and the lectin effects on neutrophil function. Biomed Pharmacother 1995;49:153-8.. PubMed
  10. Bussing A, Regnery A, Schweizer K. Effects of Viscum album L. on cyclophosphamide-treated peripheral blood mononuclear cells in vitro: sister chromatid exchanges and activation/proliferation marker expression. Cancer Lett 1995;94:199-205.. PubMed
  11. Deliorman D, Calis I, Ergun F. A new acyclic monoterpene glucoside from Viscum album ssp. album. Fitoterapia 2001;72:101-5. PubMed
  12. Finall AI, McIntosh SA, Thompson WD. Subcutaneous inflammation mimicking metastatic malignancy induced by injection of mistletoe extract. BMJ 2006;333:1293-4. PubMed
  13. Bauer C, Oppel T, Rueff F, Przybilla B. Anaphylaxis to viscotoxins of mistletoe (Viscum album) extracts. Ann Allergy Asthma Immunol 2005;94:86-9. PubMed
  14. Schoffski P, Breidenbach I, Krauter J, et al. Weekly 24 h infusion of aviscumine (rViscumin): A phase I study in patients with solid tumours. Eur J Cancer 2005;41:1431-8.
  15. Chernyshov VP, Omelchenko LI, Heusser P, and et al. Immunomodulatory actions of Viscum album (Iscador) in children with recurrent respiratory disease as a result of the Chernobyl nuclear accident. Complementary Therapies in Medicine 1997;5(3):141-146. DOI
  16. Chernyshov, V. P., Heusser, P., Omelchenko, L. I., Chernyshova, L. I., Vodyanik, M. A., Vykhovanets, E. V., Galazyuk, L. V., Pochinok, T. V., Gaiday, N. V., Gumenyuk, M. E., Zelinsky, G. M., Schaefermeyer, H., and Schaefermeyer, G. Immunomodulatory and cl
  17. Kim HJ, Kim H, Ahn JH, Suk JH. Liver injury induced by herbal extracts containing mistletoe and kudzu. J Altern Complement Med 2015;21(3):180-5. PubMed
  18. Kienle GS, Grugel R, Kiene H. Safety of higher dosages of Viscum album L. in animals and humans--systematic review of immune changes and safety parameters. BMC Complement Altern Med. 2011 Aug 28;11:72. PubMed
  19. Schad F, Atxner J, Buchwald D, Happe A, Popp S, Kröz M, Matthes H. Intratumoral Mistletoe (Viscum album L) Therapy in Patients With Unresectable Pancreas Carcinoma: A Retrospective Analysis. Integr Cancer Ther. 2014 Jul;13(4):332-40.
  20. Steele ML, Axtner J, Happe A, Kröz M, Matthes H, Schad F. Adverse Drug Reactions and Expected Effects to Therapy with Subcutaneous Mistletoe Extracts (Viscum album L.) in Cancer Patients. Evid Based Complement Alternat Med. 2014;2014:724258.
  21. Steele ML, Axtner J, Happe A, Kröz M, Matthes H, Schad F. Safety of Intravenous Application of Mistletoe (Viscum album L.) Preparations in Oncology: An Observational Study. Evid Based Complement Alternat Med. 2014;2014:236310.
  22. von Schoen-Angerer T, Wilkens J, Kienle GS, Kiene H, Vagedes J. High-Dose Viscum album Extract Treatment in the Prevention of Recurrent Bladder Cancer: A Retrospective Case Series. Perm J. 2015 Fall;19(4):76-83.
  23. Nazaruk J, Orlikowski P. Phytochemical profile and therapeutic potential of Viscum album L. Nat Prod Res. 2016;30(4):373-85.
  24. Bussing A, Stumpf C, Troger W, Schietzel M. Course of mitogen-stimulated T lymphocytes in cancer patients treated with Viscum album extracts. Anticancer Res. 2007 Jul-Aug;27(4C):2903-10.
  25. Noh D, Park JS, Lee DY. Acute respiratory distress syndrome after Viscum album pleurodesis for primary spontaneous pneumothorax. Koren J THorac Cariodvasc Surg. 2017 Feb;50(1):64-67.
  26. Schad F, Axtner J, Kroz M, Matthes H, Steele ML. Safety of combined treatment with monoclonal antibodies and Viscum album L preparations. Integr Cancer Ther. 2018 Mar;17(1):41-51.
  27. Thronicke A, Steele ML, Grah C, Matthes B, Schad F. Clinical safety of combined therapy of immune checkpoint inhibitors and Viscum album L. therapy in patients with advanced or metastatic cancer. BMC Complement Altern Med. 2017 Dec 13;17(1):534. PubMed
  28. Khan T, Ali S, Qayyum R, Hussain I, Wahid F, Shah AJ. Intestinal and vascular smooth muscle relaxant effect of Viscum album explains its medicinal use in hyperactive gut disorders and hypertension. BMC Complement Altern Med. 2016 Jul 27;16:251. PubMed
  29. Cho SJ, Kim SW, Chang JW. Acute pneumonitis consequent on pleurodesis with Viscum album extract: severe chest images but benign clinical course. Multidiscip Respir Med. 2014 Nov 27;9(1):61. PubMed
  30. Steele ML, Axtner J, Happe A, Kroz M, Matthes H, Schad F. Use and safety of intratumoral application of European mistletoe (Visum album L) preparations in oncology. Integr Cancer Ther. 2015 Mar;14(2):140-8.
  31. Zuzak TJ, Wasmuth A, Bernitzki S, Schwermer M, Längler A. Safety of high-dose intravenous mistletoe therapy in pediatric cancer patients: A case series. Complement Ther Med. 2018;40:198-202. PubMed
  32. Kim JD, Choi JW, Park HO, et al. Chemical pleurodesis with Viscum album L. extract for secondary spontaneous pneumothorax in elderly patients. J Thorac Dis 2020;12(10):5440-5445. PubMed
  33. Baek JH, Jeon Y, Han KW, Jung DH, Kim KO. Effect of mistletoe extract on tumor response in neoadjuvant chemoradiotherapy for rectal cancer: a cohort study. World J Surg Oncol 2021;19(1):178. PubMed
  34. Casetti F, Rafei-Shamsabadi D, Müller S. Grade II-anaphylaxis after subcutaneous injection of mistletoe extract. Contact Dermatitis 2021;85(4):462-5.
  35. Cogo E, Elsayed M, Bhardwaj S, et al. Mistletoe Extracts during the Oncological Perioperative Period: A Systematic Review and Meta-Analysis of Human Randomized Controlled Trials. Curr Oncol 2023;30(9):8196-8219. PubMed

See these in context on the European Mistletoe monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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