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Dietary supplement

Extra Strength Burdock Root 450 mg 4:1 Extract Ingredients & Drug Interactions

by TerraVita Premium Collection

Extra Strength Burdock Root 450 mg 4:1 Extract label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Extra Strength Burdock Root 450 mg 4:1 Extract against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Extra Strength Burdock Root 450 mg 4:1 Extract is a dietary supplement by TerraVita Premium Collection with 1 active ingredient. Its ingredients are commonly taken for skin conditions like acne and eczema, digestive support, diuretic ('detox') and blood purifier.Based on those ingredients, 122 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Burdock root extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Extra Strength Burdock Root 450 mg 4:1 Extract by TerraVita Premium Collection

Ask about any prescription or over-the-counter medication and we check it for interactions with Extra Strength Burdock Root 450 mg 4:1 Extract by TerraVita Premium Collection — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Extra Strength Burdock Root 450 mg 4:1 Extract by TerraVita Premium Collection

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 30, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: a 4:1 concentrated burdock root extract at 450 mg per capsule. The extract is standardized to be four times the strength of the raw root material.

The capsule itself is made from gelatin and water.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Burdock product and its label doesn't state a use — see Burdock's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence we hold doesn't support claims that burdock works for acne, aging skin, breast cancer, common cold, or atopic dermatitis (eczema). For all of these uses, the data available shows insufficient reliable evidence to rate whether it's effective.

If you're considering burdock for one of these purposes, the science hasn't established it yet.

The evidence, ingredient by ingredient Burdock

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Burdock is generally well tolerated when eaten as food and appears safe for short-term use in healthy adults, though human safety data are limited. It's rarely caused adverse effects historically.

Safety data advise against medicinal use during pregnancy due to lack of safety information and possible effects on the uterus. The same caution applies to breastfeeding — there isn't enough data to know it's safe, so medicinal use should be avoided.

Allergic reactions (including severe ones like anaphylaxis) are rare but possible. Contact dermatitis can occur, particularly with prolonged use of the root oil or burdock plasters.

A single case of liver injury was reported after taking an herbal detox tea containing burdock and other ingredients, but it's unclear whether burdock was responsible.

Side effects, ingredient by ingredient Burdock

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Burdock.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 122 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take anticoagulant or antiplatelet drugs (blood thinners like warfarin, or drugs like aspirin or clopidogrel), check your exact medications with your doctor or pharmacist before starting this product — a Moderate interaction is documented. No other medication interactions are documented in our data for the ingredients we could check.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Burdock has been used traditionally for a long time and is generally well tolerated, but the evidence doesn't establish that it works for the conditions people most often use it for. The main caution is with blood thinners and antiplatelet medications — if you take any of those, check with your doctor or pharmacist before starting.

Avoid medicinal use if you're pregnant or breastfeeding.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Feb 21, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Extra Strength Burdock Root 450 mg 4:1 Extract, straight from the product label.

Brand TerraVita Premium Collection
Barcode (UPC) 064435112547
Net contents 100 Capsule(s)
Market status On market
Date entered into DSLD Feb 21, 2023
DSLD ID 286468
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Extra Strength Burdock Root 450 mg 4:1 Extract by TerraVita Premium Collection, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
100
UPC/BARCODE
064435112547
IngredientAmount% DV
Burdock root extract450 mg--

Other ingredients: Gelatin, Water

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Statement of Identity

A Dietary Supplement

Brand IP Statement(s)

Copyright 2004 TerraVita - Distributed by ZooScape LLC, All Rights Reserved.

Suggested/Recommended/Usage/Directions

Directions Take 1 capsule, 3 times daily, with meals.

General Statements

TerraVita is an exclusive line of premium natural products that use the finest, purest and most potent ingredients in the world. TerraVita's hallmarks are the highest possible standards of purity, potency, stability and freshness. All products are prepared with the greatest quality control, from raw materials through the entire manufacturing process, right up to the moment your product is sealed for freshness and shipped to you.

Please recycle!

FDA Disclaimer Statement

Statements not evaluated by FDA. Product not intended to diagnose, treat, cure, or prevent any disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Extra Strength Burdock Root 450 mg 4:1 Extract by TerraVita Premium Collection label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Extra Strength Burdock Root 450 mg 4:1 Extract label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Extra Strength Burdock Root 450 mg 4:1 Extract by TerraVita Premium Collection

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container100 Amounts shown are per serving.

Burdock root extract

Interacts with
122 drugs
450 mg per serving

Burdock is a traditional herb most often used for skin problems and as a so-called 'blood purifier,' but high-quality human studies are lacking and mo...

Burdock root extract monograph & interactions

Other (inactive) ingredients: Gelatin, Water. These complete the product’s ingredient list but are not active constituents.

Interaction report

Extra Strength Burdock Root 450 mg 4:1 Extract by TerraVita Premium Collection Drug Interactions

Want to check YOUR meds against Extra Strength Burdock Root 450 mg 4:1 Extract?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
122Drugs
122 Moderate

Ingredients driving the most interactions

Burdock root extract 122

Individual Drug Interactions

The ingredients in Extra Strength Burdock Root 450 mg 4:1 Extract interact with 122 drugs. Click any drug to see the details.

1 of the 1 ingredient in Extra Strength Burdock Root 450 mg 4:1 Extract interact with drugs. Each result below shows which ingredient is responsible. Burdock root extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Extra Strength Burdock Root 450 mg 4:1 Extract with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Burdock root extract1 drug type · 122 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, taking burdock with anticoagulant or antiplatelet drugs might increase the risk of bleeding.

In vitro research shows that lignans from burdock reduce rabbit platelet aggregation by inhibiting platelet activating factor. This interaction has not been reported in humans.

Likelihood Possible Evidence D
Burdock root extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Extra Strength Burdock Root 450 mg 4:1 Extract, from the product label.

TerraVita Premium Collection

See all TerraVita Premium Collection products
Name
TerraVita Fine Whole Herbs
City
Brampton
State
Ontario
Pharmacist Counseling Corner

Extra Strength Burdock Root 450 mg 4:1 Extract by TerraVita Premium Collection: Common Questions

Does Extra Strength Burdock Root 450 mg 4:1 Extract by TerraVita Premium Collection interact with any medications?
Yes. Based on its ingredients, Extra Strength Burdock Root 450 mg 4:1 Extract has a known interaction with 122 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Extra Strength Burdock Root 450 mg 4:1 Extract contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm pregnant or breastfeeding?
The safety data advise against medicinal use during pregnancy due to possible effects on the uterus and lack of safety information. The same goes for breastfeeding. Talk with your doctor or pharmacist before taking this product if you're pregnant, planning to become pregnant, or breastfeeding.
What is burdock root extract, and what is the 4:1 ratio?
Burdock root is a plant root that's been used traditionally in various cultures. The 4:1 extract means the product is concentrated — four pounds of raw burdock root are processed down to one pound of extract, making it four times as potent as the raw material.
Does this actually work for acne, eczema, or other skin conditions?
The reliable evidence we hold doesn't establish that burdock works for acne, aging skin, eczema, or the other uses listed on this product. The data are insufficient to say whether it helps or doesn't.
What adverse effects might I have?
Most people who've used burdock tolerate it well, especially when consumed as food. Allergic reactions (including severe ones) are rare. Contact dermatitis can happen, especially with prolonged skin contact or use of the root oil. A single case of liver problems was reported, but it's unclear if burdock was the cause.
Can I take this with blood thinners?
Lab research suggests compounds in burdock might increase bleeding risk if taken with anticoagulant or antiplatelet drugs (blood thinners and antiplatelet medications like warfarin, aspirin, or clopidogrel). This hasn't been confirmed in humans, but because it's a documented concern, check with your doctor or pharmacist before combining this product with any blood thinner.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Extra Strength Burdock Root 450 mg 4:1 Extract label
Go deeper

The Full Monographs Behind Extra Strength Burdock Root 450 mg 4:1 Extract’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Burdock

Interacts with 122 drugs

Burdock is a traditional herb most often used for skin problems and as a so-called 'blood purifier,' but high-quality human studies are lacking and most claims are not well proven. It is wid...

Read the full Burdock monograph →
Sources

Sources & How We Checked

Extra Strength Burdock Root 450 mg 4:1 Extract's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 11 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Burdock 11 references
  1. Iwakami S, Wu JB, Ebizuka Y, Sankawa U. Platelet activating factor (PAF) antagonists contained in medicinal plants: lignans and sesquiterpenes. Chem Pharm Bull (Tokyo) 1992;40:1196-8. PubMed
  2. Sasaki Y, Kimura Y, Tsunoda T, Tagami H. Anaphylaxis due to burdock. Int J Dermatol 2003;42:472-3. PubMed
  3. Rhoads PM, Tong TG, Banner W Jr, Anderson R. Anticholinergic poisonings associated with commercial burdock root tea. J Toxicol Clin Toxicol 1984-85;22:581-4. PubMed
  4. Rodriguez P, Blanco J, Juste S, et al. Allergic contact dermatitis due to burdock (Arctium lappa). Contact Dermatitis 1995;33:134-5.
  5. Kassler, W. J., Blanc, P., and Greenblatt, R. The use of medicinal herbs by human immunodeficiency virus-infected patients. Arch Intern Med 1991;151(11):2281-2288. DOI
  6. Chan, Y. S., Cheng, L. N., Wu, J. H., Chan, E., Kwan, Y. W., Lee, S. M., Leung, G. P., Yu, P. H., and Chan, S. W. A review of the pharmacological effects of Arctium lappa (burdock). Inflammopharmacology. 2011;19(5):245-254. PubMed
  7. Breed, F. B. and Kuwabara, T. Burdock ophthalmia. Arch Ophthalmol 1966;75(1):16-20.
  8. Bryson, P. D., Watanabe, A. S., Rumack, B. H., and Murphy, R. C. Burdock root tea poisoning. Case report involving a commercial preparation. JAMA 5-19-1978;239(20):2157. DOI
  9. <p>Fletcher GF<span>, </span>Cantwell JD. Burdock root tea poisoning. JAMA <span>1978 Oct 6;240(15):1586.</span></p> DOI
  10. Latif A, Fichadiya H, Abid F, Capo G. Herbal Teas and Thrombocytopenia: A Curious Case of Yellow Dock and Burdock-Induced Thrombocytopenia. Eur J Case Rep Intern Med 2022;9(3):003247. PubMed
  11. Niazi B, Ahmed K, Ahmed M, Ali S, Song K, Elias S. Drug-Induced Liver Injury from Herbal Liver Detoxification Tea. Case Rep Gastroenterol 2022;16(3):612-617. PubMed

See these in context on the Burdock monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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