No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

Extra Strength Lecithin Ingredients & Drug Interactions

by NOW

Softgel Capsule Category: Fat/fatty Acid
No known interaction
The interaction bottom line No known interaction

Extra Strength Lecithin is a dietary supplement by NOW with 1 active ingredient. Its ingredients are commonly taken for high cholesterol, liver health, brain and memory support.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Extra Strength Lecithin by NOW

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • “Soy Lecithin” is listed as a grouped ingredient — the label gives one combined amount (3.60 g) without saying how much of each component you get.

This product contains 2 active ingredients: phosphatidyl choline and soy lecithin (which is broken down into its component parts, including phosphatidyl choline). Phosphatidyl choline is a natural fatty compound found in cell membranes and is involved in nerve and liver function.

The softgel capsule itself is an inactive ingredient—the outer shell that holds everything together.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Phosphatidylcholine's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: supports brain and nerve function.
  • We looked for evidence on: Age-related cognitive decline, Alzheimer disease, Dementia, Memory, cognitive support, neurological health.
  • The closest evidence on file: Phosphatidylcholine is rated "Insufficient Reliable Evidence To Rate" for Alzheimer disease (Natural Medicines).
  • Also on file: Phosphatidylcholine is rated "Insufficient Reliable Evidence To Rate" for Memory, Dementia.

Phosphatidyl choline is possibly effective for ulcerative colitis (an inflammatory bowel condition), though the evidence is limited. For nonalcoholic fatty liver disease, alcohol-related liver disease, Alzheimer disease, and anxiety, the evidence isn't established enough to rate it one way or the other.

If you're considering this product for one of those other conditions, talk it over with your doctor about whether it makes sense for you.

The evidence, ingredient by ingredient Lecithin Phosphatidylcholine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Phosphatidyl choline is generally well tolerated when taken by mouth. At very high doses—especially 30 grams a day or more—it may cause digestive upset.

More commonly reported side effects at lower doses include altered taste, bloating, diarrhea, nausea, vomiting, itching, and sweating. Choline (a component of phosphatidyl choline) is needed during pregnancy, but safety data on supplement use beyond food sources in pregnancy isn't well studied.

For breastfeeding, there isn't enough reliable information. Talk with your doctor or pharmacist before taking this product if you're pregnant or breastfeeding.

Side effects, ingredient by ingredient Lecithin Phosphatidylcholine

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for the ingredients we could check. We were not able to verify polyunsaturated fat, so if that's a concern, ask your pharmacist or doctor to review the full ingredient list before you start.

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. No medication interactions are currently documented, and safety information is well characterized.

NOW Extra Strength Lecithin may be worth considering if you're interested in phosphatidyl choline's role in nerve and liver health, though solid evidence exists only for ulcerative colitis. If you're pregnant, breastfeeding, or take any medications, check with your own doctor or pharmacist first—no documented interactions doesn't mean there are none, and your personal health situation matters.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Oct 1, 2012.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Extra Strength Lecithin, straight from the product label.

Brand NOW
Barcode (UPC) 733739022301
Net contents 100 Softgel(s)
Market status On market
Date entered into DSLD Oct 1, 2012
DSLD ID 13531
Product type Fat/fatty Acid
Supplement form Softgel Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Extra Strength Lecithin by NOW, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Softgel(s)
Maximum serving Sizes:
3 Softgel(s)
Servings per container
33
UPC/BARCODE
733739022301
IngredientAmount% DV
Calories30 {Calories}--
Calories from Fat20 {Calories}--
Total Fat2 g3%
Saturated Fat0 g--
Polyunsaturated Fat2 g--
Trans Fat0 g--
Soy Lecithin3.6 g--
Phosphatidyl Choline1.14 g--

Other ingredients: Softgel Capsule

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

SUGGESTED USAGE: As a dietary supplement, take 2-3 softgels daily with food. Consider taking these other NOW(R) products: L-Carnitine, Omega-3 Fish Oil and CoQ10.

Brand IP Statement(s)

NOW(R) Extra Strength, Non-GMO Lecithin Softgels have over twice the Phosphatidyl Choline (1,140 mg per serving) as in our regular strength product (540 mg per serving). Phosphatidyl Choline comprises a major portion of our brain and nervous system. Lecithin also has naturally occurring essential fatty acids and Inositol. Lecithin aids in emulsifying fats, enabling them to be dispersed in water.*

Precautions

Consult physician if pregnant/nursing, taking medication, or have a medical condition.

Keep out of reach of children.

Caution: For adults only.

Produced in a GMP facility that processes other ingredients containing these allergens.

Formula

380 mg Phosphatidyl Choline • Non-GMO - 1200 mg Lecithin

General Statements

• Supports Brain & Nerve Function*

Please Recycle.

SOFTGEL SIZE

NERVOUS SYSTEM SUPPORT

For more product information visit www.nowfoods.com/2230

Natural color variations may occur in this product.

FDA Statement of Identity

A Dietary Supplement

Seals/Symbols

GMP QUALITY ASSURED

FDA Disclaimer Statement

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Formulation

Not manufactured with yeast, wheat, gluten, milk, egg, fish, shellfish or tree nut ingredients.

Storage

Store in a cool, dry place after opening.

General

CODE 2230 V4

See for yourself

Extra Strength Lecithin by NOW label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Extra Strength Lecithin by NOW

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size2 Softgel(s) Dosage formSoftgel Capsule Servings per container33 Amounts shown are per serving.

Soy Lecithin

No known
interactions
3.6 g per serving

Lecithin is a natural fatty substance found in foods and made by the body that is widely used as a supplement and food emulsifier. Evidence supporting...

Soy Lecithin monograph & interactions

Other (inactive) ingredients: Softgel Capsule. These complete the product’s ingredient list but are not active constituents.

Interaction report

Extra Strength Lecithin by NOW Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Extra Strength Lecithin. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Extra Strength Lecithin, from the product label.

NOW

See all NOW products
Name
NOW FOODS
Street Address
395 S. Glen Ellyn Rd.
City
Bloomingdale
State
IL
ZipCode
60108
Pharmacist Counseling Corner

Extra Strength Lecithin by NOW: Common Questions

Does Extra Strength Lecithin by NOW interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Extra Strength Lecithin. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Extra Strength Lecithin contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What does phosphatidyl choline actually do?
Phosphatidyl choline is a natural fatty compound found in your cell membranes. It plays a role in nerve and liver function and is being studied for its role in digestive and brain health. It's possibly effective for ulcerative colitis, though evidence for other conditions is still being gathered.
What side effects should I watch for?
Most commonly, people report altered taste, bloating, diarrhea, nausea, vomiting, itching, or sweating. These tend to be mild. At very high doses—30 grams a day or more—digestive upset becomes more likely. If you notice any of these effects, dial back the dose or stop and talk to your pharmacist.
Is it safe to take while pregnant?
Choline is actually needed during pregnancy, but the safety of supplements beyond what you get from food hasn't been well studied. Talk with your doctor before taking this product if you're pregnant—they can help you figure out if it's right for you.
Can I take this while breastfeeding?
There isn't enough reliable data on supplement use of phosphatidyl choline while breastfeeding. Speak with your healthcare provider first to get personalized advice for your situation.
Does this product actually work?
The evidence is mixed and depends on what you're taking it for. Phosphatidyl choline is possibly effective for ulcerative colitis. For other conditions like fatty liver disease, Alzheimer disease, or anxiety, the evidence isn't established yet. Your doctor can help you decide if it's worth trying for your specific situation.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Extra Strength Lecithin is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Extra Strength Lecithin label
Sources

Sources & How We Checked

Extra Strength Lecithin's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 24 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Lecithin 9 references
  1. Buchman AL, Dubin M, Jenden D, et al. Lecithin increases plasma free choline and decreases hepatic steatosis in long-term total parenteral nutrition patients. Gastroenterology 1992;102:1363-70.
  2. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline (2000). Washington, DC: National Academy Press, 2000. Available at: http://b
  3. Chatellier G, Lacomblez L. Tacrine (tetrahydroaminoacridine; THA) and lecithin in senile dementia of the Alzheimer type: a multicentre trial. Groupe Francais d'Etude de la Tetrahydroaminoacridine. BMJ 1990;300:495-9.
  4. Gelenberg AJ, Dorer DJ, Wojcik JD, et al. A crossover study of lecithin treatment of tardive dyskinesia. J Clin Psychiatry 1990;51:149-53.
  5. Little A, Levy R, Chuaqui-Kidd P, Hand D. A double-blind, placebo controlled trial of high-dose lecithin in Alzheimer's disease. J Neurol Neurosurg Psychiatry 1985;48:736-42. PubMed
  6. Palm M, Moneret-Vautrin DA, Kanny G, et al. Food allergy to egg and soy lecithins. Allergy 1999;54:1116-7. PubMed
  7. Drachman DA, Glosser G, Fleming P, et al. Memory decline in the aged: treatment with lecithin and physostigmine. Neurology 1982;32:944-50. PubMed
  8. Gelenberg, A. J., Doller-Wojcik, J. C., and Growdon, J. H. Choline and lecithin in the treatment of tardive dyskinesia: preliminary results from a pilot study. Am J Psychiatry 1979;136(6):772-776. PubMed
  9. Electronic Code of Federal Regulations. Title 21, Chapter 1, Subchapter B, Part 184: Direct food substances affirmed as Generally Recognized as Safe. Subpart B - listing of specific substances affirmed as GRAS. Sec. 184.1400 Lecithin. Available at: https:

See these in context on the Lecithin monograph →

Phosphatidylcholine 15 references
  1. Domino EF, May WW, Demetriou S, et al. Lack of clinically significant improvement of patients with tardive dyskinesia following phosphatidylcholine therapy. Biol Psychiatry 1985;20:1189-96. PubMed
  2. Aronson PJ, Lorincz AL. Promotion of palmar sweating with oral phosphatidylcholine. Acta Derm Venereol 1985;65:19-24. DOI
  3. Hexsel DM, Serra M, de Oliveira Dal'Forno T, et al. Cosmetic uses of injectable phosphatidylcholine on the face. Otolaryngol Clin North Am 2005;38:1119-29. PubMed
  4. Kopera D, Binder B, Toplak H, et al. Histopathologic changes after intralesional application of phosphatidylcholine for lipoma reduction: report of a case. Am J Dermatopathol 2006;28:331-3. PubMed
  5. Rittes PG. The use of phosphatidylcholine for correction of lower lid bulging due to prominent fat pads. Dermatol Surg 2001;27:391-2. PubMed
  6. Rotunda AM, Kolodney MS. Mesotherapy and phosphatidylcholine injections: historical clarification and review. Dermatol Surg 2006;32:465-80. PubMed
  7. Hexsel D, Serra M, Mazzuco R, et al. Phosphatidylcholine in the treatment of localized fat. J Drugs Dermatol 2003;2:511-8.
  8. Hasengschwandtner F. Phosphatidylcholine treatment to induce lipolysis. Cosmet Dermatol 2005;4:308-13. PubMed
  9. Rittes PG. The use of phosphatidylcholine for correction of localized fat deposits. Aesthetic Plast Surg 2003;27:315-8. PubMed
  10. Ablon G, Rotunda AM. Treatment of lower eyelid fat pads using phosphatidylcholine: clinical trial and review. Dermatol Surg 2004;30:422-7. PubMed
  11. Loguercio C, Andreone P, Brisc C, et al. Silybin combined with phosphatidylcholine and vitamin E in patients with nonalcoholic fatty liver disease: a randomized controlled trial. Free Radic Biol Med 2012;52(9):1658-65. PubMed
  12. Panos, J. M., Palson, R., Johnson, R., Portmann, B., and Williams, R. Polyunsaturated phosphatidylcholine for acute alcoholic hepatitis: a double blind randomized placebo controlled trial. Eur.J.Gastroenterol 1990;2:351-355.
  13. Stremmel W, Braun A, Hanemann A, Ehehalt R, Autschbach F, Karner M. Delayed release phosphatidylcholine in chronic-active ulcerative colitis: a randomized, double-blinded, dose finding study. J Clin Gastroenterol 2010;44(5):e101-7. PubMed
  14. Stremmel W, Ehehalt R, Autschbach F, Karner M. Phosphatidylcholine for steroid-refractory chronic ulcerative colitis: a randomized trial. Ann Intern Med. 2007;147(9):603-10. PubMed
  15. Stremmel W, Vural H, Evliyaoglu O, Weiskirchen R. Delayed Release Phosphatidylcholine is Effective for Treatment of Ulcerative Colitis: A Meta-Analysis. Dig Dis 2021;39(5):508-515. PubMed

See these in context on the Phosphatidylcholine monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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