Interactions on record — worth a quick check against your medications. Based on 5 of 6 ingredients. Check your meds →
Dietary supplement

Eye Ingredients & Drug Interactions

by iwi

Eye label
See full label image
Softgel Capsule Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 23, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Eye against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Eye is a dietary supplement by iwi with 6 active ingredients. Its ingredients are commonly taken for body and breath odor reduction, wound healing (topical), detoxification.Based on those ingredients, 672 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Algae Oil, Chlorophyll, Zinc. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Eye by iwi

Ask about any prescription or over-the-counter medication and we check it for interactions with Eye by iwi — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Eye by iwi

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 11 of its 11 active ingredients.
  • “Omega-3 Fatty Acids” is listed as a grouped ingredient — the label gives one combined amount (219 mg) without saying how much of each component you get.
  • “Algae Oil” is listed as a grouped ingredient — the label gives one combined amount (688 mg) without saying how much of each component you get.
  • “Total Omega Fatty Acids” is listed as a grouped ingredient — the label gives one combined amount (285 mg) without saying how much of each component you get.

iwi Eye is an 11-ingredient softgel capsule centered on omega fatty acids — a blend including eicosapentaenoic acid and docosahexaenoic acid (two types of omega-3s found in fish), omega-6 and omega-9 fatty acids, omega-7 fatty acids, and other omega-3 varieties sourced from algae oil. The product also contains chlorophyll, lutein, zinc, copper, and polar lipids.

Inactive ingredients include the softgel shell and excipients (fillers and binders).

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: Eye health and vision support.
  • We looked for evidence on: Age-related macular degeneration (AMD), Asthenopia (eye strain), Cataracts, Diabetic retinopathy, Dry eye, Presbyopia — and 2 related terms.
  • The strongest evidence on file: Lutein is rated "Possibly Effective" for Age-related macular degeneration (AMD) (Natural Medicines).
  • Also on file: Lutein is rated "Possibly Effective" for Cataracts.
  • Also on file: Zinc is rated "Possibly Effective" for Age-related macular degeneration (AMD).

Lutein is possibly effective for age-related macular degeneration (AMD) and cataracts, two common eye conditions. Zinc is effective for zinc deficiency and likely effective for Wilson disease, and possibly effective for acne and age-related macular degeneration.

We hold no effectiveness ratings for chlorophyll, the various omega fatty acid blends (omega-3, omega-6, omega-9, omega-7), or polar lipids for eye health or other uses. The evidence for omega-6 fatty acids suggests they may be possibly ineffective for high cholesterol, heart disease, and multiple sclerosis when used as supplements.

The evidence, ingredient by ingredient Chlorophyll Zinc Copper Algal Oil Lutein

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 5 of the 5 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 5 of 5.
  • General safety write-ups exist for 5 of 5.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Chlorophyll is generally well tolerated for short-term use, but long-term safety data are limited. The most common side effect is photosensitization — increased sensitivity to sun exposure — and in rare cases, oral chlorophyll has been associated with a condition called pseudoporphyria (blisters that form easily on the hands).

Chlorophyll is not recommended in pregnancy due to insufficient safety data, and safety during breastfeeding is unknown. Zinc is generally safe in recommended amounts; common side effects at higher doses are nausea, vomiting, diarrhea, abdominal cramps, and a metallic taste.

High doses above 40 mg daily for adults may increase the risk of copper deficiency over time. Copper is safe in food and standard supplement amounts, and contact dermatitis from copper is rare.

Lutein from food and typical supplement doses is generally well tolerated; doses up to 20 mg daily have not caused reported adverse effects. Lutein is likely safe in pregnancy and lactation.

Side effects, ingredient by ingredient Chlorophyll Zinc Copper Algal Oil Lutein

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 3 of the 5 matched ingredients can interact with medications — Chlorophyll, Copper, Zinc.
  • The most serious interaction on file is rated Moderate.
  • For scale: 406 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check with your pharmacist before taking this product if you use photosensitizing medications (drugs that increase sun sensitivity), methotrexate, any antibiotics (especially quinolones, tetracyclines, cephalexin, or penicillamine), HIV medications including ritonavir, integrase inhibitors, or bictegravir/emtricitabine/tenofovir alafenamide, chemotherapy drugs like cisplatin, or oral contraceptives. Timing and spacing of doses may be necessary to protect how well your medications work.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

iwi Eye is an omega fatty acid and micronutrient formula aimed at eye health, with lutein and zinc showing modest evidence for age-related macular degeneration. If you take antibiotics, HIV medications, chemotherapy, methotrexate, penicillamine, or oral contraceptives, check your exact medications with the tool below before starting — timing and spacing matter.

Talk to your pharmacist or doctor, especially if you're pregnant, breastfeeding, or have a history of copper deficiency.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 5 of 11 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated May 22, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Eye, straight from the product label.

Brand iwi
Net contents 30 Softgel(s)
Market status On market
Date entered into DSLD May 22, 2021
DSLD ID 247668
Product type Other Combinations
Supplement form Softgel Capsule
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Eye by iwi, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Softgel(s)
Maximum serving Sizes:
1 Softgel(s)
Servings per container
30
IngredientAmount% DV
Calories10 Calorie(s)--
Omega-3 Fatty Acids219 mg--
Eicosapentaenoic Acid100 mg--
Docosahexaenoic Acid115 mg--
Cholesterol10 mg3%
Total Fat1 Gram(s)1%
Chlorophyll6 mg--
Omega-6 Fatty Acids20 mg--
Omega-9 Fatty Acids10 mg--
Zinc25 mg167%
Other Omega-3 Fatty Acids4 mg--
Copper1 mg50%
Algae Oil688 mg--
Omega-7 Fatty Acids36 mg--
Polar Lipids60 mg--
Total Omega Fatty Acids285 mg--
Lutein7 mg--

Other ingredients: Softgel Shell, Excipients

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Better living begins within

DHA is a primary constituent of your retina and confers the ability to adjust to different lighting conditions. Not only do we avoid harming the ocean and the life in it, we also give back 1% of our net sales to Ocean Unite. iwi is good for every living thing. Learn more at: iwilife.com & oceanunite.org

Recyclable Kegan et al., 2013 Lipids Health Dis Made from recycled bottles

Ocean Unite

Formula

Almega PL, our proprietary form of algae Omega-3, offers 50% better absorption than fish, krill and other algae oils. Additionally, we added a blend of zinc, copper and lutein to protect against harmful blue light.

Omega-3 + Zinc, Copper and Lutein

Formulation

Sustainably farmed in the USA, iwi algae is cultivated in the desert with saltwater and powered by the sun.

Non GMO Certified by NSF Gluten free

Vegan

50% more absorption Sustainably sourced plant-based

Made from algae

Protect Nourish Replenish

Contains no: sugar, gelatin, nuts, wheat, yeast, pollen, dairy, hidden additives or artificial flavors or colors.

Seals/Symbols

Non GMO Certified by NSF

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Directions: Take 1 softgel daily.

Precautions

Keep out of the reach of children.

Do not use if safety seal is broken or missing.

Storage

Store in a cool, dry place.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Eye by iwi label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Eye label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Eye by iwi

These are the 6 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Softgel(s) Dosage formSoftgel Capsule Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Chlorophyll

Interacts with
337 drugs
6 mg per serving

Chlorophyll is the green pigment found in plants and algae, and supplements often use a stable form called chlorophyllin. It is most studied for reduc...

Chlorophyll monograph & interactions

Zinc

Interacts with
67 drugs
25 mg per serving Form: Zinc Oxide

Zinc is an essential mineral that your body needs for immune function, wound healing, taste, and smell. Most people get enough from food, but suppleme...

Zinc monograph & interactions

Copper

Interacts with
31 drugs
1 mg per serving Form: Copper Gluconate

Copper is an essential trace mineral your body needs in small amounts for making red blood cells, supporting nerves and bones, and helping enzymes wor...

Copper monograph & interactions

Algae Oil

Interacts with
375 drugs
688 mg per serving

Algal oil is a plant-based source of the omega-3 fats DHA and (in some products) EPA, making it a popular alternative to fish oil for vegetarians, veg...

Algae Oil monograph & interactions
  • › Total Omega Fatty Acids

Polar Lipids

60 mg per serving

Lutein

No known
interactions
7 mg per serving Form: Marigold Tagetes erecta flower extract

Lutein is a plant-based antioxidant pigment that concentrates in the eye, and the best evidence suggests it (often combined with zeaxanthin) may help...

Lutein monograph & interactions

Other (inactive) ingredients: Softgel Shell, Excipients. These complete the product’s ingredient list but are not active constituents.

Interaction report

Eye by iwi Drug Interactions

Want to check YOUR meds against Eye?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
672Drugs
640 Moderate 32 Minor

Ingredients driving the most interactions

Algae Oil 375
Chlorophyll 337
Zinc 67
Copper 31

Individual Drug Interactions

The ingredients in Eye interact with 672 drugs. Click any drug to see the details.

4 of the 6 ingredients in Eye interact with drugs. Each result below shows which ingredient is responsible. Algae Oil Chlorophyll Zinc Copper

Each ingredient & the kinds of drugs it affects

For each ingredient in Eye with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Algae Oil3 drug types · 375 drugs

Antidiabetes Drugs

Theoretically, taking algal oil with antidiabetes drugs might interfere with the effects of antidiabetes drugs and reduce their effects.
Most algal oil contains docosahexaenoic acid (DHA). Clinical research in people with type 2 diabetes, including those taking antidiabetes drugs, shows that taking DHA 4 grams daily for 6 weeks increases fasting blood glucose levels by about 18 mg/dL when compared with taking olive oil.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, taking algal oil with antihypertensive drugs might increase the risk of hypotension.
Algal oil usually contains docosahexaenoic acid (DHA) and/or eicosapentaenoic acid (EPA). There is evidence that fish oil, which also contains DHA and EPA, can modestly lower blood pressure and might have additive effects in patients treated with antihypertensive drugs.

Likelihood Possible Evidence D
Anticoagulant/Antiplatelet Drugs

Theoretically, algal oil may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
The risk of interaction is highest for algal oil containing high amounts (> 2 grams daily) of eicosapentaenoic acid (EPA), or EPA and docosahexaenoic acid (DHA). High doses of EPA or oils containing EPA and DHA can reduce platelet aggregation in humans. However, most algal oil contains very little EPA and larger amounts of DHA. While some conflicting evidence exist, most research shows that DHA alone does not affect blood clotting.

Likelihood Unlikely Evidence D
Algae Oil full monograph & interactions

Chlorophyll2 drug types · 337 drugs

Methotrexate (Trexall, Others)

Theoretically, chlorophyll may reduce the clearance of methotrexate.
In one case report, a 54-year-old male developed delayed clearance of intravenous high-dose methotrexate with concomitant use of chlorophyll. When chlorophyll was stopped 2 days prior to methotrexate treatment, methotrexate clearance was unaffected.

Likelihood Possible Evidence B
Photosensitizing Drugs

Theoretically, concomitant use of chlorophyll with photosensitizing drugs may have additive effects.
Chlorophyll has been reported to cause photosensitization. In two case reports, pseudoporphyria developed after oral intake of chlorophyll. Theoretically, concomitant use with other photosensitizing drugs may exacerbate this effect.

Likelihood Probable Evidence B
Chlorophyll full monograph & interactions

Zinc10 drug types · 67 drugs

Bictegravir/Emtricitabine/Tenofovir Alafenamide (Biktarvy)

Theoretically, zinc might decrease levels of bictegravir/emtricitabine/tenofovir alafenamide by reducing its absorption.
Advise patients that bictegravir/emtricitabine/tenofovir alafenamide should be taken at least 2 hours before or 6 hours after zinc containing products.

Likelihood Probable Evidence D
Cephalexin (Keflex)

Zinc might decrease cephalexin levels by chelating with cephalexin in the gut and preventing its absorption.
A pharmacokinetic study shows that zinc sulfate 250 mg taken concomitantly with cephalexin 500 mg decreases peak levels of cephalexin by 31% and reduces the exposure to cephalexin by 27%. Also, taking zinc sulfate 3 hours before cephalexin decreases peak levels of cephalexin by 11% and reduces the exposure to cephalexin by 18%. By decreasing cephalexin levels, zinc might increase the risk of treatment failure. This effect does not occur when zinc is taken 3 hours after the cephalexin dose. To avoid an interaction, advise patients take zinc sulfate 3 hours after taking cephalexin.

Likelihood Probable Evidence B
Cisplatin (Platinol-Aq)

Theoretically, zinc might interfere with the therapeutic effects of cisplatin.
Animal research suggests that zinc stimulates tumor cell production of the protein metallothionein, which binds and inactivates cisplatin. It is not known whether zinc supplements or high dietary zinc intake can cause clinically significant interference with cisplatin therapy. Cisplatin might also increase zinc excretion.

Likelihood Possible Evidence D
Integrase Inhibitors

Theoretically, taking zinc along with integrase inhibitors might decrease the levels and clinical effects of these drugs.
Zinc is a divalent cation. Pharmacokinetic studies have shown that other divalent cations such as calcium and iron can decrease blood levels of the integrase inhibitor dolutegravir through chelation.

Likelihood Possible Evidence D
Penicillamine (Cuprimine, Depen)

Zinc might reduce the levels and clinical effects of penicillamine.
By forming an insoluble complex with penicillamine, zinc interferes with penicillamine absorption and activity. Zinc supplements reduce the efficacy of low-dose penicillamine (0.5-1 gram/day), but do not seem to affect higher doses (1-2.75 gram/day), provided dosing times are separated. Advise patients to take zinc and penicillamine at least 2 hours apart.

Likelihood Probable Evidence B
Quinolone Antibiotics

Zinc can decrease the levels and clinical effects of quinolones antibiotics.
Quinolones form complexes with zinc in the gastrointestinal tract, reducing absorption of both the quinolone and zinc if taken at the same time. Advise patients to take these drugs at least 2 hours before, or 4-6 hours after, zinc supplements.

Likelihood Probable Evidence B
Ritonavir (Norvir)

Zinc modestly reduces levels of ritonavir.
Clinical research shows that zinc might reduce serum ritonavir levels by chelating with ritonavir in the gut and preventing its absorption. In patients with HIV, ritonavir is taken with atazanavir to prevent the metabolism and increase the effects of atazanavir. A pharmacokinetic study shows that, in patients being treated with atazanavir/ritonavir, co-administration of zinc sulfate (Solvazinc tablets) 125 mg as a single dose or as multiple daily doses for 2 weeks reduces plasma levels of ritonavir by about 16%. However, atazanavir levels still remains high enough to prevent HIV virus replication. Therefore, the decrease in ritonavir levels is not likely to be clinically significant.

Likelihood Probable Evidence B
Tetracycline Antibiotics

Zinc might reduce levels of tetracycline antibiotics.
Tetracyclines form complexes with zinc in the gastrointestinal tract, which can reduce absorption of both the tetracycline and zinc when taken at the same time. Taking zinc sulfate 200 mg with tetracycline reduces absorption of the antibiotic by 30% to 40%. Demeclocycline and minocycline cause a similar interaction. However, doxycycline does not seem to interact significantly with zinc. Advise patients to take tetracyclines at least 2 hours before, or 4-6 hours after, zinc supplements to avoid any interactions.

Likelihood Probable Evidence B
Amiloride (Midamor)

Amiloride can modestly reduce zinc excretion and increase zinc levels.
Clinical research shows that amiloride can reduce urinary zinc excretion, especially at doses of 10 mg per day or more. This zinc-sparing effect can help to counteract zinc losses caused by thiazide diuretics, but it is unlikely to cause zinc toxicity at usual amiloride doses. The other potassium-sparing diuretics, spironolactone (Aldactone) and triamterene (Dyrenium), do not seem to have a zinc-sparing effect.

Likelihood Probable Evidence B
Atazanavir (Reyataz)

Zinc modestly reduces levels of atazanavir, although this effect does not seem to be clinically significant.
Clinical research shows that zinc might decrease serum atazanavir levels by chelating with atazanavir in the gut and preventing its absorption. Although a single dose of zinc sulfate (Solvazinc tablets) 125 mg orally does not affect atazanavir concentrations in patients being treated with atazanavir/ritonavir, co-administration of zinc sulfate 125 mg daily for 2 weeks reduces plasma levels of atazanavir by about 22% in these patients. However, despite this decrease, atazanavir levels still remain at high enough concentrations for the prevention of HIV virus replication.

Likelihood Probable Evidence B
Zinc full monograph & interactions

Copper2 drug types · 31 drugs

Penicillamine (Cuprimine, Depen)

Theoretically, taking copper with penicillamine might decrease the absorption of penicillamine; separate dosing by at least 2 hours.
Copper chelates penicillamine, which decreases its absorption and may reduce its clinical effects.

Likelihood Probable Evidence D
Contraceptive Drugs

Theoretically, taking copper with contraceptive drugs might increase the levels and toxic effects of copper.
A meta-analysis of clinical studies suggests that chronic use of oral contraceptives increases serum copper levels by a mean of 57 mcg/dL. In most people, this resulted in levels above the normal reference range for copper.

Likelihood Possible Evidence D
Copper full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Eye, from the product label.

iwi

See all iwi products
Name
iwi
City
Houston
State
TX
ZipCode
77056
Web Address
iwilife.com
Pharmacist Counseling Corner

Eye by iwi: Common Questions

Does Eye by iwi interact with any medications?
Yes. Based on its ingredients, Eye has a known interaction with 672 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Eye contains 6 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is iwi Eye safe to take while pregnant or breastfeeding?
Chlorophyll in this product is not recommended during pregnancy because there isn't enough safety data. Safety during breastfeeding is also unknown. Lutein is likely safe in both pregnancy and lactation. There is no pregnancy or breastfeeding safety data on file for zinc and copper in this product. Talk with your doctor or pharmacist for personalized advice before taking it while pregnant or nursing.
What is lutein, and why is it in an eye supplement?
Lutein is a yellow pigment naturally found in the eye's retina. It's possibly effective for age-related macular degeneration and cataracts, two conditions that affect vision as you age. That's why it's included in this formula.
Can this supplement cause sun sensitivity?
Yes — chlorophyll, one of the active ingredients, can cause photosensitization, which means your skin becomes more sensitive to sunlight. If you take this product and notice increased sun sensitivity, speak with your pharmacist or dermatologist.
How much zinc is in each capsule, and could it cause side effects?
The product facts don't list the exact amount of zinc per capsule. Common side effects of zinc at higher doses are nausea, vomiting, diarrhea, and a metallic taste. If you experience any of these, reduce the dose or stop and talk with your pharmacist.
Does this product contain fish, and is it safe for people with fish allergies?
The product facts don't specify whether it contains fish allergens or how the omega-3 fatty acids are sourced. Because it includes eicosapentaenoic acid and docosahexaenoic acid (components typically from fish), talk with your pharmacist about allergen content if you have a fish allergy.
Is there enough evidence that this supplement actually works for eye health?
Lutein is possibly effective for macular degeneration and cataracts, and zinc is possibly effective for macular degeneration. For the omega fatty acids and other ingredients, we hold no established evidence for eye health in our data. If you're looking for eye support, lutein and zinc are the ingredients with the most backing.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Eye label
Go deeper

The Full Monographs Behind Eye’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Chlorophyll

Interacts with 337 drugs

Chlorophyll is the green pigment found in plants and algae, and supplements often use a stable form called chlorophyllin. It is most studied for reducing body and fecal odor and as a topical...

Read the full Chlorophyll monograph → Herb & supplement monograph

Zinc

Interacts with 67 drugs

Zinc is an essential mineral that your body needs for immune function, wound healing, taste, and smell. Most people get enough from food, but supplements can help correct or prevent a defici...

Read the full Zinc monograph → Herb & supplement monograph

Copper

Interacts with 31 drugs

Copper is an essential trace mineral your body needs in small amounts for making red blood cells, supporting nerves and bones, and helping enzymes work. Most people get enough copper from fo...

Read the full Copper monograph → Herb & supplement monograph

Algal Oil

Interacts with 375 drugs

Algal oil is a plant-based source of the omega-3 fats DHA and (in some products) EPA, making it a popular alternative to fish oil for vegetarians, vegans, and people who dislike fish. There...

Read the full Algal Oil monograph → Herb & supplement monograph

Lutein

Lutein is a plant-based antioxidant pigment that concentrates in the eye, and the best evidence suggests it (often combined with zeaxanthin) may help slow progression of age-related macular...

Read the full Lutein monograph →
Sources

Sources & How We Checked

Eye's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 218 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Docosahexaenoic Acid (dha) 49 references
  1. Akedo I, Ishikawa H, Nakamura T, et al. Three cases with familial adenomatous polyposis diagnosed as having malignant lesions in the course of a long-term trial using docosahexanoic acid (DHA)-concentrated fish oil capsules (abstract). Jpn J Clin Oncol PubMed
  2. Prisco D, Paniccia R, Bandinelli B, et al. Effect of medium-term supplementation with a moderate dose of n-3 polyunsaturated fatty acids on blood pressure in mild hypertensive patients. Thromb Res 1998;1:105-12.
  3. Grimsgaard S, Bonaa KH, Hansen JB, Nordoy A. Highly purified eicosapentaenoic acid and docosahexaenoic acid in humans have similar triacylglycerol-lowering effects but divergent effects on serum fatty acids. Am J Clin Nutr 1997;66:649-59.
  4. Toft I, Bonaa KH, Ingebretsen OC, et al. Effects of n-3 polyunsaturated fatty acids on glucose homeostasis and blood pressure in essential hypertension. A randomized, controlled trial. Ann Intern Med 1995;123:911-8.
  5. Sacks FM, Hebert P, Appel LJ, et al. Short report: the effect of fish oil on blood pressure and high-density lipoprotein-cholesterol levels in phase I of the trials of hypertension prevention. J Hypertens 1994;12:209-13.
  6. Vandongen R, Mori TA, Burke V, et al. Effects on blood pressure of omega 3 fats in subjects at increased risk of cardiovascular disease. Hypertension 1993;22:371-9. PubMed
  7. FDA. Center for Food Safety and Applied Nutrition. Letter regarding dietary supplement health claim for omega-3 fatty acids and coronary heart disease. Available at: http://www.fda.gov/ohrms/dockets/dockets/95s0316/95s-0316-Rpt0272-38-Appendix-D-Reference
  8. Pedersen HS, Mulvad G, Seidelin KN, et al. N-3 fatty acids as a risk factor for haemorrhagic stroke. Lancet 1999;353:812-3. PubMed
  9. Ito Y, Suzuki K, Imai H, et al. Effects of polyunsaturated fatty acids on atrophic gastritis in a Japanese population. Cancer Lett 2001;163:171-8. PubMed
  10. Kris-Ehterton PM, Harris WS, Appel LJ, et al. Fish consumption, fish oil, omega-3 fatty acids, and cardiovascular disease. Circulation 2002;106:2747-57. PubMed
  11. Woodman RJ, Mori TA, Burke V, et al. Effects of purified eicosapentaenoic and docosahexaenoic acids on glycemic control, blood pressure, and serum lipids in type 2 diabetic patients with treated hypertension. Am J Clin Nutr 2002;76:1007-15.. PubMed
  12. Marangell LB, Martinez JM, Zboyan HA, et al. A double-blind, placebo-controlled study of the omega-3 fatty acid docosahexaenoic acid in the treatment of major depression. Am J Psychiatry 2003;160:996-8.. PubMed
  13. Leng GC, Smith FB, Fowkes FG, et al. Relationship between plasma essential fatty acids and smoking, serum lipids, blood pressure and haemostatic and rheological factors. Prostaglandins Leukot Essent Fatty Acids 1994;51:101-8. PubMed
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Copper 11 references
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Algal Oil 43 references
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Lutein 2 references
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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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