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Dietary supplement

EyesAlive Vision Nutrition Ingredients & Drug Interactions

by Swanson

Capsule Category: Other Combinations
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

EyesAlive Vision Nutrition is a dietary supplement by Swanson with 4 active ingredients. Its ingredients are commonly taken for eye and vision health, antioxidant support, diarrhea and digestive upset.Based on those ingredients, 871 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Astaxanthin, Bilberry extract, OmniXan Zeaxanthin. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of EyesAlive Vision Nutrition by Swanson

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 4 of its 4 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

EyesAlive Vision Nutrition contains 4 active ingredients: bilberry extract, astaxanthin, lutein, and zeaxanthin. Bilberry and zeaxanthin are carotenoid antioxidants found naturally in plants; astaxanthin is a related pigment from algae and seafood.

Lutein is a plant pigment concentrated in leafy greens and the eye. All four are aimed at supporting eye and vision health.

The product also includes inactive ingredients — microcrystalline cellulose (a filler), gelatin (capsule material), magnesium stearate (a flow agent), silica, and astaxanthin and lutein beadlets (forms of the actives).

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: eye health and vision support.
  • We looked for evidence on: Age-related macular degeneration (AMD), Asthenopia (eye strain), Cataracts, Diabetic retinopathy, Dry eye, Glaucoma — and 4 related terms.
  • The strongest evidence on file: Lutein is rated "Possibly Effective" for Age-related macular degeneration (AMD) (Natural Medicines).
  • Also on file: Lutein is rated "Possibly Effective" for Cataracts.
  • Also on file: Zeaxanthin is rated "Possibly Effective" for Age-related macular degeneration (AMD).

The evidence for this product's ingredients varies widely. Lutein and zeaxanthin are both possibly effective for age-related macular degeneration (AMD) and lutein is possibly effective for cataracts.

Bilberry extract is rated possibly ineffective for night vision, while evidence is insufficient to rate it for AMD, atherosclerosis, chronic venous insufficiency, or age-related cognitive decline. Astaxanthin has insufficient evidence for AMD, cognitive decline, aging skin, Alzheimer disease, athletic performance, or carpal tunnel syndrome.

In short, lutein and zeaxanthin may help with AMD and lutein with cataracts, but the broader benefits of this combination are not yet well established.

The evidence, ingredient by ingredient Bilberry Astaxanthin Lutein Zeaxanthin

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 3 of the 4 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 4 of 4.
  • General safety write-ups exist for 4 of 4.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Bilberry extract is generally well tolerated when eaten as food, though concentrated supplements lack long-term safety data; the safety notes advise caution with supplement doses. Most common side effects from bilberry are dark-colored stools, flatulence, and gastrointestinal discomfort; a small number of trial participants reported mild-to-moderate flatulence or temporary GI upset.

Your tongue, teeth, and stool may turn dark blue or black. Astaxanthin is generally well tolerated, though long-term safety is limited.

A small number of trial participants experienced abdominal pain, diarrhea, or red-colored stools at typical doses. Pregnancy safety data for astaxanthin are insufficient; the safety notes advise against it in pregnancy and while breastfeeding.

Lutein from food and typical supplement doses is generally well tolerated, with no adverse effects reported at doses up to 20 mg daily. Zeaxanthin is generally well tolerated at typical supplement amounts.

Both lutein and zeaxanthin are rated likely safe in pregnancy and lactation, though supplement safety while breastfeeding has not been well studied.

Side effects, ingredient by ingredient Bilberry Astaxanthin Lutein Zeaxanthin

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 3 of the 4 matched ingredients can interact with medications — Bilberry, Astaxanthin, Zeaxanthin.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications.
  • For scale: 872 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking EyesAlive Vision Nutrition, check with your doctor or pharmacist if you take blood thinners or antiplatelet drugs (moderate risk of increased bleeding), diabetes medications (moderate risk of low blood sugar), the cancer drug erlotinib, or any drugs metabolized by your liver's CYP2E1, CYP3A4, or CYP2B6 enzymes — bilberry, astaxanthin, and zeaxanthin may change how well these drugs work or how high their levels climb in your blood.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This product may be worth considering if you're interested in eye health, especially for age-related macular degeneration or cataracts — lutein and zeaxanthin have some evidence for those. However, if you take blood thinners, diabetes medications, or drugs your liver metabolizes through the CYP2E1, CYP2A4, or CYP2B6 pathways, you'll need to check with your doctor or pharmacist before starting.

Astaxanthin isn't advised in pregnancy or while breastfeeding. Talk over your full medication list and health situation with your own healthcare provider before adding this to your routine.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 4 of 4 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Feb 25, 2019.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about EyesAlive Vision Nutrition, straight from the product label.

Brand Swanson
Barcode (UPC) 087614029153
Net contents 120 Capsule(s)
Market status On market
Date entered into DSLD Feb 25, 2019
DSLD ID 191020
Product type Other Combinations
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for EyesAlive Vision Nutrition by Swanson, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
60
UPC/BARCODE
087614029153
IngredientAmount% DV
Bilberry extract320 mg--
Astaxanthin4 mg--
Lutein20 mg--
OmniXan Zeaxanthin4 mg--

Other ingredients: Microcrystalline Cellulose, Astaxanthin powder, Gelatin, Lutein Beadlets, OmniXan beadlets, Magnesium Stearate, Silica

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Promotes a healthy and strong retina and macula Promotes healthy eyesight Fights eye fatigue and eye strain Science-Backed Quality Since 1969

Eye and Vision Health Antioxidant blend

Suggested/Recommended/Usage/Directions

Suggested use: As a dietary supplement, take two capsules per day with water before a meal.

Brand IP Statement(s)

OmniXan is a registered trademark of OmniActive Health Technologies, Ltd.

Precautions

Warning: For adults only.

Consult your physician before using this or any product if you are pregnant or nursing, taking medication, or if you have a medical condition.

Keep out of reach of children.

Do not use if seal is broken.

Storage

Store in a cool, dry place.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

FDA Statement of Identity

Dietary Supplement

General

SWU915 Rev 0 05 30 18

See for yourself

EyesAlive Vision Nutrition by Swanson label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in EyesAlive Vision Nutrition by Swanson

These are the 4 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Bilberry extract

Interacts with
275 drugs
320 mg per serving Form: Anthocyanins

Bilberry is a blueberry-like fruit rich in antioxidant plant compounds called anthocyanins, and it has a long history of traditional use for eye healt...

Bilberry extract monograph & interactions

Astaxanthin

Interacts with
671 drugs
4 mg per serving Form: natural Astaxanthin Complex

Astaxanthin is a reddish carotenoid pigment with strong antioxidant activity in the lab, and it is widely promoted for skin, eye, heart, and exercise...

Astaxanthin monograph & interactions

Lutein

No known
interactions
20 mg per serving Form: Marigold flower extract

Lutein is a plant-based antioxidant pigment that concentrates in the eye, and the best evidence suggests it (often combined with zeaxanthin) may help...

Lutein monograph & interactions

OmniXan Zeaxanthin

Interacts with
86 drugs
4 mg per serving Form: Paprika

Zeaxanthin is a carotenoid pigment that, along with lutein, concentrates in the macula of the eye and may help support long-term eye health. The stron...

OmniXan Zeaxanthin monograph & interactions

Other (inactive) ingredients: Microcrystalline Cellulose, Astaxanthin powder, Gelatin, Lutein Beadlets, OmniXan beadlets, Magnesium Stearate, Silica. These complete the product’s ingredient list but are not active constituents.

Interaction report

EyesAlive Vision Nutrition by Swanson Drug Interactions

Want to check YOUR meds against EyesAlive Vision Nutrition?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
871Drugs
871 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in EyesAlive Vision Nutrition with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Astaxanthin2 drug types · 671 drugs

Cytochrome P450 2B6 (Cyp2B6) Substrates

Theoretically, astaxanthin may decrease levels of drugs metabolized by CYP2B6.
In vitro research shows that astaxanthin induces cytochrome CYP2B6 enzyme activity in human hepatocytes. This effect has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, astaxanthin may decrease levels of drugs metabolized by CYP3A4.
In vitro research shows that astaxanthin induces CYP3A4 enzyme activity in human hepatocytes. This effect has not been reported in humans.

Likelihood Possible Evidence D

Bilberry extract4 drug types · 275 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, bilberry fruit extract might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
In vitro, animal, and clinical research suggest that anthocyanidin extracts from bilberry can inhibit platelet aggregation.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, bilberry leaf or fruit extract may increase the risk of hypoglycemia when taken with antidiabetes drugs.
Animal research suggests that bilberry leaf extract might have blood glucose-lowering activity. Also, one small clinical trial in patients with type 2 diabetes shows that taking bilberry fruit extract 470 mg as a single dose prior to an oral glucose tolerance test lowers plasma glucose levels when compared with placebo.

Likelihood Possible Evidence D
Cytochrome P450 2E1 (Cyp2E1) Substrates

Theoretically, bilberry fruit extract might decrease levels of drugs metabolized by CYP2E1.
Animal research shows that exposure to small concentrations of bilberry extract in drinking water for around one month increased CYP2E1 activity by 31%. However, exposure over a 2-month period did not increase CYP2E1 activity. This effect has not been reported in humans.

Likelihood Possible Evidence D
Erlotinib (Tarceva)

Theoretically, bilberry fruit extract might reduce the efficacy of erlotinib.
In vitro research suggests that bilberry fruit extract and its constituents, delphinidin and delphinidin-3-O-glucoside, inhibit the activity of erlotinib. This interaction has not been reported in humans.

Likelihood Possible Evidence D

OmniXan Zeaxanthin1 drug type · 86 drugs

Antidiabetes Drugs

Theoretically, taking zeaxanthin with antidiabetes drugs might increase the risk of hypoglycemia.
In an animal diabetic model, zeaxanthin has hypoglycemic effects. However, population research has found that increasing intake of dietary zeaxanthin plus lutein does not decrease the risk of developing type 2 diabetes.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for EyesAlive Vision Nutrition, from the product label.

Swanson

See all Swanson products
Name
Swanson Health Products
City
Fargo
State
ND
ZipCode
58104
Phone Number
1-800-437-4148
Web Address
swanson.com
Pharmacist Counseling Corner

EyesAlive Vision Nutrition by Swanson: Common Questions

Does EyesAlive Vision Nutrition by Swanson interact with any medications?
Yes. Based on its ingredients, EyesAlive Vision Nutrition has a known interaction with 871 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
EyesAlive Vision Nutrition contains 4 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is this safe to take while I'm pregnant or breastfeeding?
Bilberry and lutein are rated likely safe in pregnancy and lactation. Zeaxanthin is also rated likely safe in pregnancy, though supplement safety while breastfeeding hasn't been well studied. Astaxanthin is different — safety data are not available, so the advice is to avoid it during pregnancy and breastfeeding. Talk with your doctor or pharmacist about what's right for your situation.
What do these ingredients actually do in my eyes?
All four ingredients — bilberry, astaxanthin, lutein, and zeaxanthin — are antioxidants that naturally accumulate in the eye and retina. Lutein and zeaxanthin have the strongest evidence: they're possibly effective for age-related macular degeneration and lutein is possibly effective for cataracts. Bilberry and astaxanthin's benefits for the eye are less well established.
Will this help my night vision?
No, bilberry is actually rated possibly ineffective for night vision, so if that's your main reason for taking this product, the evidence doesn't support it. The other ingredients in this product don't have established effects on night vision either.
Are there any side effects I should expect?
Bilberry most commonly causes dark-colored stools, flatulence, and GI discomfort; your stool and tongue may turn dark blue or black. Astaxanthin can cause abdominal pain, diarrhea, or red-colored stools. Lutein and zeaxanthin are generally well tolerated with no reported side effects at typical doses. Overall, this product is generally well tolerated, though long-term safety data are limited.
Does lutein interact with any medications?
No interactions are documented in our data for lutein. However, the other ingredients in this product — bilberry, astaxanthin, and zeaxanthin — do have documented interactions, so you'll still want to check your full medication list before taking it.
What are the inactive ingredients?
The product contains microcrystalline cellulose (a filler), gelatin (capsule material), magnesium stearate, silica, and beadlets of astaxanthin and lutein. If you have allergies to any of these, check the label or talk with your pharmacist.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if EyesAlive Vision Nutrition is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

EyesAlive Vision Nutrition label
Sources

Sources & How We Checked

EyesAlive Vision Nutrition's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 23 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Bilberry 14 references
  1. Cignarella A, Nastasi M, Cavalli E, Puglisi L. Novel lipid-lowering properties of Vaccinium myrtillus L. leaves, a traditional antidiabetic treatment, in several models of rat dyslipidaemia: a comparison with ciprofibrate. Thromb Res 1996;84:311-22. PubMed
  2. Morazzoni P, Magistretti MJ. Activity of Myrtocyan, an anthosyanoside complex from Vaccinium myrtillus (VMA), on platelet aggregation and adhesiveness. Fitoterapia 1990;61:13-21.
  3. Erlund, I., Koli, R., Alfthan, G., Marniemi, J., Puukka, P., Mustonen, P., Mattila, P., and Jula, A. Favorable effects of berry consumption on platelet function, blood pressure, and HDL cholesterol. Am J Clin Nutr 2008;87(2):323-331. PubMed
  4. Hawrelak, J. A. and Myers, S. P. Effects of two natural medicine formulations on irritable bowel syndrome symptoms: a pilot study. J Altern Complement Med 2010;16(10):1065-1071. PubMed
  5. Morazzoni P and Magistretti MJ. Effects of Vaccinium myrtillus anthocyanosides on prostacyclin-like activity in rat arterial issue. Fitoterapia 1986;57:11-14.
  6. Pulliero G, Montin S, Bettini V, and et al. Ex vivo study of the inhibitory effects of Vaccinium myrtillus anthocyanosides on human platelet aggregation. Fitoterapia 1989;60:69-75.
  7. Bottecchia D. Preliminary report on the inhibitory effect of vaccinium myrtillus anthocyanosides on platelet aggregation and clot retraction. Fitoterapia 1987;48:3-8.
  8. Fdez, M., Zaragoza, F., and Alvarez, P. In vitro platelet aggregation effects of anthocyanosides of vaccinium myrtilus L. Anales de la Real Academia de Farmacia 1983;49:79-90.
  9. Biedermann L, Mwinyi J, Scharl M, Frei P, Zeitz J, Kullak-Ublick GA, et al. Bilberry ingestion improves disease activity in mild to moderate ulcerative colitis-an open pilot study. 2013 May;7(4):271-9. PubMed
  10. Hoggard N, Cruickshank M, Moar KM, Bestwick C, Holst J, Russell W, et al. A single supplement of a standardized bilberry (Vaccinium myrtillus L.) extract (36% wet weight anthocyanins) modifies glycaemic response in individuals with type 2 diabetes control
  11. Aichinger G, Pahlke G, Nagel LJ, Berger W, Marko D. Bilberry extract, its major phenolic compounds, and soy isoflavone genistein antagonize the cytostatic drug erlotinib in human epithelial cells. Food Funct 2016;7(8):3628-36.
  12. Prokop J, Lněničková K, Cibicek N, et al. Effect of bilberry extract (Vaccinium myrtillus L.) on drug-metabolizing enzymes in rats. Food Chem Toxicol 2019;129:382-90. PubMed
  13. Chan SW, Chu TTW, Choi SW, Benzie IFF, Tomlinson B. Impact of short-term bilberry supplementation on glycemic control, cardiovascular disease risk factors, and antioxidant status in Chinese patients with type 2 diabetes. Phytother Res 2021. Online ahead o PubMed
  14. Bøhn SK, Myhrstad MCW, Thoresen M, et al. Bilberry/red grape juice decreases plasma biomarkers of inflammation and tissue damage in aged men with subjective memory impairment -a randomized clinical trial. BMC Nutr 2021;7(1):75. PubMed

See these in context on the Bilberry monograph →

Astaxanthin 3 references
  1. Kupcinskas L, Lafolie P, Lignell A, et al. Efficacy of the natural antioxidant astaxanthin in the treatment of functional dyspepsia in patients with or without Helicobacter pylori infection: A prospective, randomized, double blind, and placebo-controlled
  2. Kistler, A., Liechti, H., Pichard, L., Wolz, E., Oesterhelt, G., Hayes, A., and Maurel, P. Metabolism and CYP-inducer properties of astaxanthin in man and primary human hepatocytes. Arch.Toxicol. 2002;75(11-12):665-675. PubMed
  3. Choi HD, Youn YK, Shin WG. Positive effects of astaxanthin on lipid profiles and oxidative stress in overweight subjects. Plant Foods Hum Nutr. 2011;66:363-369. PubMed

See these in context on the Astaxanthin monograph →

Lutein 2 references
  1. Brown L, Rimm EB, Seddon JM, et al. A prospective study of carotenoid intake and risk of cataract extraction in US men. Am J Clin Nutr 1999;70:517-24. PubMed
  2. Chasan-Taber L, Willett WC, Seddon JM, et al. A prospective study of carotenoid and vitamin A intakes and risk of cataract extraction in US women. Am J Clin Nutr 1999;70:509-16. PubMed

See these in context on the Lutein monograph →

Zeaxanthin 4 references
  1. Montonen J, Knekt P, Jarvinen R, Reunanen A. Dietary antioxidant intake and risk of type 2 diabetes. Diabetes Care 2004;27:362-6. PubMed
  2. Leermakers ET, Darweesh SK, Baena CP, et al. The effects of lutein on cardiometabolic health across the life course: a systematic review and meta-analysis. Am J Clin Nutr 2016;103(2):481-94. PubMed
  3. Kou L, Du M, Zhang C, Dai Z, Li X, Zhang B. The Hypoglycemic, Hypolipidemic, and Anti-Diabetic Nephritic Activities of Zeaxanthin in Diet-Streptozotocin-Induced Diabetic Sprague Dawley Rats. Appl Biochem Biotechnol 2017;182(3):944-955. PubMed
  4. Xu X, Zhao X, Berde Y, Low YL, Kuchan MJ. Milk and Plasma Lutein and Zeaxanthin Concentrations in Chinese Breast-Feeding Mother-Infant Dyads With Healthy Maternal Fruit and Vegetable Intake. J Am Coll Nutr 2019;38(2):179-184. PubMed

See these in context on the Zeaxanthin monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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