Interactions on record — worth a quick check against your medications. Based on 3 of 4 ingredients. Check your meds →
Dietary supplement

Fortify Mood & Stress Ingredients & Drug Interactions

by Nature's Way

Fortify Mood & Stress label
See full label image
Capsule Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Fortify Mood & Stress against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Fortify Mood & Stress is a dietary supplement by Nature's Way with 4 active ingredients. Its ingredients are commonly taken for stress and anxiety, sleep problems, fatigue and low energy.Based on those ingredients, 1,493 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Ashwagandha (Sensoril brand) root and leaf extract, Lactobacillus helveticus Rosell-52ND, Bifidobacterium longum Rosell-175. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Fortify Mood & Stress by Nature's Way

Ask about any prescription or over-the-counter medication and we check it for interactions with Fortify Mood & Stress by Nature's Way — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Fortify Mood & Stress by Nature's Way

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 30, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 1 of its 4 active ingredients.
  • “Fortify Digestive & Emotional Health 5 billion CFU Proprietary Probiotic Blend” is a proprietary blend — the label gives one combined amount (259 mg) without saying how much of each component you get.

This product contains 4 active ingredients. The main one is ashwagandha (Sensoril brand) root and leaf extract, an adaptogenic herb traditionally used to support mood and stress resilience.

The other three are probiotics — beneficial bacteria meant to support digestive and emotional health. You're getting Lactobacillus helveticus Rosell-52ND, Bifidobacterium longum Rosell-175, and HOWARU Bifidobacterium lactis HN019, together providing 5 billion CFU (colony-forming units, a measure of live organisms).

The capsule itself is made from plant-derived material, and the inactive ingredients are potato starch, cellulose, magnesium stearate, and silica — standard excipients that help hold the capsule together.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: helps reduce stress and promotes emotional well-being.
  • We looked for evidence on: Anxiety, Stress, Generalized anxiety disorder (GAD), Depression, Psychological well-being, Insomnia — and 2 related terms.
  • The strongest evidence on file: Ashwagandha is rated "Possibly Effective" for Anxiety (Natural Medicines).
  • Also on file: Ashwagandha is rated "Possibly Effective" for Generalized anxiety disorder (GAD), Insomnia, Stress.
  • Also on file: Ashwagandha is rated "Insufficient Reliable Evidence To Rate" for Depression, Psychological well-being.

Ashwagandha in this product is rated possibly effective for insomnia, anxiety, stress, and generalized anxiety disorder. The evidence for attention deficit-hyperactivity disorder (ADHD) is insufficient, so we can't say whether it helps there.

As for the probiotic strains, the evidence we hold doesn't establish their effectiveness for any of the conditions listed — allergic rhinitis, antibiotic-associated diarrhea, cognitive function, depression, diarrhea, and exercise-induced respiratory infections all have insufficient reliable evidence to rate them.

The evidence, ingredient by ingredient Ashwagandha Lactobacillus Helveticus Bifidobacterium Longum

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 3 of the 3 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 3 of 3.
  • General safety write-ups exist for 3 of 3.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Ashwagandha is generally well tolerated short-term in healthy adults, though long-term and quality safety data are limited. The most common side effects are mild — diarrhea, nausea, stomach upset, vomiting — and don't typically occur at standard doses.

Rare but serious concerns include acute liver failure and hepatitis; case reports also describe drowsiness, headache, and in one patient, intracranial bleeding (though causality isn't clear). Ashwagandha is considered likely unsafe in pregnancy due to traditional concerns about miscarriage risk, and there's not enough safety information to recommend it while breastfeeding.

The probiotics (Lactobacillus helveticus and Bifidobacterium longum) are generally well tolerated in healthy people. Rare side effects include abdominal discomfort, flatulence, and in one case, dry cough.

People who are seriously ill or immunocompromised should be cautious; the risk of these bacteria causing serious infection is low but documented in vulnerable patients. For Bifidobacterium longum specifically, pregnancy and lactation are rated possibly safe, but data are limited — check with your doctor.

We have no pregnancy or breastfeeding safety information on file for Lactobacillus helveticus or HOWARU Bifidobacterium lactis HN019.

Side effects, ingredient by ingredient Ashwagandha Lactobacillus Helveticus Bifidobacterium Longum

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 3 of the 3 matched ingredients can interact with medications — Ashwagandha, Bifidobacterium Longum, Lactobacillus Helveticus.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: immunosuppressants / transplant drugs; diabetes medications.
  • For scale: 1,494 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, check with your doctor or pharmacist if you take any of the following: medications that damage the liver (hepatotoxic drugs); blood pressure medications (antihypertensive drugs); diabetes medications; sedatives, sleeping aids, or benzodiazepines; immune-suppressing drugs; thyroid hormone; or antibiotics. Ashwagandha may increase sedation, lower blood pressure further, raise low blood sugar, or interfere with how your liver or thyroid work.

Antibiotics will also kill the live probiotic organisms in this capsule, reducing its effectiveness — space them at least a few hours apart if you must use both.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This product might help if you're looking to manage everyday stress or mild anxiety, and the ashwagandha has some evidence behind it for those uses. However, it's not for everyone — if you take blood pressure medication, diabetes drugs, sedatives, or any medication that affects your liver or immune system, you need to check with your doctor or pharmacist first, because ashwagandha can change how those drugs work.

People who are pregnant, breastfeeding, or seriously ill should also talk to their healthcare provider before starting. Use the medication checker on this page with your exact prescriptions, and discuss any questions with your own doctor or pharmacist.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 3 of 4 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jun 16, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Fortify Mood & Stress, straight from the product label.

Brand Nature's Way
Barcode (UPC) 033674124499
Net contents 30 Delayed Release Capsule(s)
Market status On market
Date entered into DSLD Jun 16, 2022
DSLD ID 267830
Product type Other Combinations
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Fortify Mood & Stress by Nature's Way, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
30
UPC/BARCODE
033674124499
IngredientAmount% DV
Total Carbohydrate1 Gram(s)1%
Ashwagandha (Sensoril brand) root and leaf extract250 mg--
Fortify Digestive & Emotional Health 5 billion CFU Proprietary Probiotic Blend259 mg--
Lactobacillus helveticus Rosell-52ND0 NP--
Bifidobacterium longum Rosell-1750 NP--
HOWARU Bifidobacterium lactis HN0190 NP--

Other ingredients: Potato Starch, Cellulose, plant-derived Capsule, Magnesium Stearate, Silica

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Helps reduce stress & promotes emotional well-being Supports digestive health One capsule, multiple benefits

No artificial colors.

Potency of this product guaranteed until expiration date when bottle is stored under recommended conditions.

Certified Gluten Free GFCO.ORG Non GMO project verified nongmoproject.org

Targeted care Mood & stress

5 Billion active cultures, guaranteed! Innovative new bottle technology helps ensure this product will deliver 5 Billion live probiotic cultures until the date of expiration without refrigeration to help support emotional and digestive health. Targeted Delivery Each capsule is resistant to the harmful effects of stomach acid and distributes live cultures to the proper area of the small intestine and colon, right where they're needed most!

Potency of live cultures measured in Colony Forming units (CFU).

No artificial colors Gluten free

Emotional well-being Digestive balance

Storage

Store in a dry place at 73 degrees F (23 degrees C) or below.

Keep tightly closed. Can be sotred at room temperature or refrigerated. Avoid excessive heat and direct sunlight.

No refrigeration required

Precautions

Keep out of reach of children.

Safety sealed with inner seal. Do not use if seal is broken or missing.

Warning: Do not use if you are pregnant. If you are nursing, diabetic, or taking any medications, consult a healthcare professional before use.

Contains milk and soy.

Brand IP Statement(s)

Howaru Probiotic Quality You Can Feel Howaru is a registered trademark of International Flavors & Fragrances Inc. or its affiliates.

Sensoril is a registered trademark of Natreon, Inc. and is protected under U.S. Patent No. 7,318,938. 2021 Nature's Way Brands, LLC

Seals/Symbols

Certified Gluten Free GFCO.ORG Non GMO project verified nongmoproject.org

Certified Authentic Tru-ID DNA authenticated probiotic strains

FDA Disclaimer Statement

These statements have not been evaluated by the Food & Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Formula

Probiotics & Ashwagandha

Powerful formula for daily mood and stress support Fortify Mood & Stress was formulated with clinically researched probiotic strains and 250 mg of Ashwagandha to support your overall emotional health by decreasing stress and normalizing the body's response to modern stressors. Emotional Well-Being Find your Zen with the specially formulated probiotic that includes clinically researched Lactobacillus helveticus and Bifidobacterium longum strains in the amount shown to promote emotional well-being and help support the body's physical and emotional response to stress. Stress Less with Ashwagandha Used traditionally to help balance the body's response to stressors, Ashwagandha has been shown to promote relaxation and support a positive mood. Healthy Digestive Balance The Fortify Mood & Stress formula contains clinically researched Bifidobacterium lactis HN019 in the amount shown to support digestive health, giving you a great foundation for your busy day.

Researched probiotic strains

Contains the Doctor Preferred Probiotic for regularity

FDA Statement of Identity

Probiotic Supplement

Suggested/Recommended/Usage/Directions

Recommendation: Adults take 1 capsule daily with a meal.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Fortify Mood & Stress by Nature's Way label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Fortify Mood & Stress label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Fortify Mood & Stress by Nature's Way

These are the 4 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Ashwagandha (Sensoril brand) root and leaf extract

Interacts with
1,372 drugs
250 mg per serving

Ashwagandha is an Ayurvedic herb most often taken to help with stress, anxiety, and sleep, and some small studies suggest it may help, though the evid...

Ashwagandha (Sensoril brand) root and leaf extract monograph & interactions

Fortify Digestive & Emotional Health 5 billion CFU Proprietary Probiotic Blend

259 mg per serving

Other (inactive) ingredients: Potato Starch, Cellulose, Plant-derived Capsule, Magnesium Stearate, Silica. These complete the product’s ingredient list but are not active constituents.

Interaction report

Fortify Mood & Stress by Nature's Way Drug Interactions

Want to check YOUR meds against Fortify Mood & Stress?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
1,493Drugs
1,051 Moderate 442 Minor

Ingredients driving the most interactions

Ashwagandha (Sensoril brand) root and leaf extract 1,372
Lactobacillus helveticus Rosell-52ND 182
Bifidobacterium longum Rosell-175 182

Individual Drug Interactions

The ingredients in Fortify Mood & Stress interact with 1,493 drugs. Click any drug to see the details.

3 of the 4 ingredients in Fortify Mood & Stress interact with drugs. Each result below shows which ingredient is responsible. Ashwagandha (Sensoril brand) root and leaf extract Lactobacillus helveticus Rosell-52ND Bifidobacterium longum Rosell-175

Each ingredient & the kinds of drugs it affects

For each ingredient in Fortify Mood & Stress with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Ashwagandha (Sensoril brand) root and leaf extract10 drug types · 1,372 drugs

Antidiabetes Drugs

Theoretically, taking ashwagandha with antidiabetes drugs might increase the risk of hypoglycemia.
There is preliminary clinical evidence suggesting that ashwagandha might lower blood glucose levels. Theoretically, ashwagandha might have additive effects when used with antidiabetes drugs and increase the risk of hypoglycemia.

Likelihood Possible Evidence B
Antihypertensive Drugs

Theoretically, taking ashwagandha with antihypertensive drugs might increase the risk of hypotension.
Animal research suggests that ashwagandha might lower systolic and diastolic blood pressure. Theoretically, ashwagandha might have additive effects when used with antihypertensive drugs and increase the risk of hypotension.

Likelihood Possible Evidence D
Benzodiazepines

Theoretically, taking ashwagandha might increase the sedative effects of benzodiazepines.
There is preliminary evidence that ashwagandha might have an additive effect with diazepam (Valium) and clonazepam (Klonopin). This may also occur with other benzodiazepines.

Likelihood Possible Evidence D
Cns Depressants

Theoretically, taking ashwagandha might increase the sedative effects of CNS depressants.
Ashwagandha seems to have sedative effects. Theoretically, this may potentiate the effects of barbiturates, other sedatives, and anxiolytics.

Likelihood Possible Evidence D
Hepatotoxic Drugs

Theoretically, taking ashwagandha with hepatotoxic drugs might increase the risk of liver damage.
Ashwagandha has been linked to cases of acute hepatitis, liver failure, hepatic encephalopathy, autoimmune hepatitis, the need for liver transplantation, and death due to liver failure.

Likelihood Possible Evidence D
Immunosuppressants

Theoretically, taking ashwagandha might decrease the effects of immunosuppressants.
Ashwagandha has demonstrated immunostimulant effects in humans. Animal research has shown that ashwagandha can attenuate the immunosuppression caused by cyclophosphamide.

Likelihood Possible Evidence D
Thyroid Hormone

Ashwagandha might increase the effects and adverse effects of thyroid hormone.
Concomitant use of ashwagandha with thyroid hormones may cause additive therapeutic and adverse effects. Preliminary clinical research and animal studies suggest that ashwagandha boosts thyroid hormone synthesis and secretion. In one clinical study, ashwagandha increased triiodothyronine (T3) and thyroxine (T4) levels by 41.5% and 19.6%, respectively, and reduced serum TSH levels by 17.4% from baseline in adults with subclinical hypothyroidism.

Likelihood Probable Evidence B
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, ashwagandha might decrease the levels and clinical effects of CYP1A2 substrates.
In vitro research shows that ashwagandha extract induces CYP1A2 enzymes.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, ashwagandha might decrease the levels and clinical effects of CYP3A4 substrates.
In vitro research shows that ashwagandha extract induces CYP3A4 enzymes.

Likelihood Possible Evidence D
Serotonergic Drugs

Some animal studies have reported that ashwagandha can enhance serotonergic transmission by altering certain serotonin (5-HT) receptors. However, there is no evidence to suggest that ashwagandha increases the risk of serotonin-related effects, and there have been no published case reports of serotonin syndrome when combined with other serotonergic drugs. Nevertheless, due to the lack of extensive studies on the matter and the fact that ashwagandha appears to affect serotonergic pathways, it would be prudent to exercise caution when combining it with drugs that affect serotonin. [References: - Effects of Withania somnifera (Ashwaga ndha) on Stress and the Stress-Related Neuropsychiatric Disorders Anxiety, Depression, and Insomnia. Curr Neuropharmacol. 2021 Sep 14; 19: 1468–1495. - A Prospective, Randomized Double-Blind, Placebo-Controlled Study of Safety and Efficacy of a High-Concentration Full-Spectrum Extract of Ashwagandha Root in Reducing Stress and Anxiety in Adults. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3573577/]

Likelihood Possible Evidence C
Ashwagandha (Sensoril brand) root and leaf extract full monograph & interactions

Lactobacillus helveticus Rosell-52ND1 drug type · 182 drugs

Antibiotic Drugs

Theoretically, taking Lactobacillus helveticus with antibiotic drugs might decrease the effectiveness of L. helveticus.
Lactobacillus helveticus preparations usually contain live and active organisms. Therefore, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and L. helveticus preparations by at least two hours.

Likelihood Probable Evidence D
Lactobacillus helveticus Rosell-52ND full monograph & interactions

Bifidobacterium longum Rosell-1751 drug type · 182 drugs

Antibiotic Drugs

Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B. longum.
Since B. longum preparations usually contain live and active organisms, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and B. longum preparations by at least 2 hours.

Likelihood Probable Evidence D
Bifidobacterium longum Rosell-175 full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Fortify Mood & Stress, from the product label.

Nature's Way

See all Nature's Way products
Name
Nature's Way Brands, LLC
City
Green Bay
State
WI
ZipCode
54311
Phone Number
1-800-962-8873
Web Address
fortifyprobiotics.com
Pharmacist Counseling Corner

Fortify Mood & Stress by Nature's Way: Common Questions

Does Fortify Mood & Stress by Nature's Way interact with any medications?
Yes. Based on its ingredients, Fortify Mood & Stress has a known interaction with 1,493 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Fortify Mood & Stress contains 4 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm pregnant?
Ashwagandha in this product is rated likely unsafe during pregnancy due to traditional concerns about miscarriage risk, so no — avoid it if you're pregnant. The probiotic data we hold don't address pregnancy safety for all strains, so talk with your doctor or pharmacist for personalized advice if you're considering it.
Can I take this while breastfeeding?
Ashwagandha is not recommended while breastfeeding because there isn't enough safety information. Bifidobacterium longum is rated possibly safe during lactation, but safety data are limited. For Lactobacillus helveticus and HOWARU Bifidobacterium lactis, we don't have breastfeeding safety information on file. Check with your doctor or pharmacist before using it.
Will this make me drowsy?
Ashwagandha has been reported to cause drowsiness in some people. If you're sensitive to sedation or plan to drive, start cautiously and see how you respond.
What if I'm taking antibiotics?
Antibiotics can kill the live probiotic organisms in this product, reducing its benefit. If you're on antibiotics, separate your doses — take the antibiotic and this product a few hours apart — and talk with your pharmacist about the timing.
Is there any evidence this actually helps with anxiety?
Ashwagandha is rated possibly effective for anxiety and generalized anxiety disorder, so there's preliminary evidence, but it's not proven. The probiotics' effects on anxiety aren't well established in the data we hold.
What side effects should I watch for?
Common mild ones are nausea, diarrhea, and stomach upset, though they're uncommon at normal doses. Rare but serious concerns include liver damage and, in one reported case, bleeding in the brain — if you develop severe abdominal pain, yellowing of skin or eyes, or unusual headache or vision changes, stop and seek medical care immediately.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Fortify Mood & Stress is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Fortify Mood & Stress label
Go deeper

The Full Monographs Behind Fortify Mood & Stress’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Ashwagandha

Interacts with 1,372 drugs

Ashwagandha is an Ayurvedic herb most often taken to help with stress, anxiety, and sleep, and some small studies suggest it may help, though the evidence is still limited. It is generally w...

Read the full Ashwagandha monograph → Herb & supplement monograph

Lactobacillus Helveticus

Interacts with 182 drugs

Lactobacillus helveticus is a lactic acid bacterium used as a probiotic, often combined with other strains in mood, gut, and general wellness products. Early research is interesting—especial...

Read the full Lactobacillus Helveticus monograph → Herb & supplement monograph

Bifidobacterium Longum

Interacts with 182 drugs

Bifidobacterium longum is a 'friendly' bacterium found naturally in the human gut and used as a probiotic. It is generally well tolerated and is most studied for digestive issues, though evi...

Read the full Bifidobacterium Longum monograph →
Sources

Sources & How We Checked

Fortify Mood & Stress's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 55 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Ashwagandha 32 references
  1. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  2. Upton R, ed. Ashwagandha Root (Withania somnifera): Analytical, quality control, and therapuetic monograph. Santa Cruz, CA: American Herbal Pharmacopoeia 2000:1-25.
  3. Davis L, Kuttan G. Effect of Withania somnifera on cyclophosphamide-induced urotoxicity. Cancer Lett 2000;148:9-17. PubMed
  4. Davis L, Kuttan G. Suppressive effect of cyclophosphamide-induced toxicity by Withania somnifera extract in mice. J Ethnopharmacol 1998;62:209-14. PubMed
  5. Mishra LC, Singh BB, Dagenais S. Scientific basis for the therapeutic use of Withania somnifera (ashwagandha): a review. Altern Med Rev 2000;5:334-46. DOI
  6. Andallu B, Radhika B. Hypoglycemic, diuretic and hypocholesterolemic effect of winter cherry (Withania somnifera, Dunal) root. Indian J Exp Biol 2000;38:607-9.
  7. Kulkarni RR, Patki PS, Jog VP, et al. Treatment of osteoarthritis with a herbomineral formulation: a double-blind, placebo-controlled, cross-over study. J Ethnopharmacol 1991;33:91-5. PubMed
  8. Ahumada F, Aspee F, Wikman G, Hancke J. Withania somnifera exract. Its effects on arterial blood pressure in anaesthetized dogs. Phytother Res 1991;5:111-14.
  9. Panda S, Kar A. Withania somnifera and Bauhinia purpurea in the regulation of circulating thyroid hormone concentrations in female mice. J Ethnopharmacol 1999;67:233-39. PubMed
  10. Panda S, Kar A. Changes in thyroid hormone concentrations after administration of ashwagandha root extract to adult male mice. J Pharm Pharmacol 1998;50:1065-68. PubMed
  11. Sehgal, V. N., Verma, P., and Bhattacharya, S. N. Fixed-drug eruption caused by ashwagandha (Withania somnifera): a widely used Ayurvedic drug. Skinmed. 2012;10(1):48-49.
  12. Agnihotri AP, Sontakke SD, Thawani VR, Saoji A, Goswami VS. Effects of Withania somnifera in patients of schizophrenia: a randomized, double blind, placebo controlled pilot trial study. Indian J Pharmacol. 2013;45(4):417-8. PubMed
  13. Biswal BM, Sulaiman SA, Ismail HC, Zakaria H, Musa KI. Effect of Withania somnifera (Ashwagandha) on the development of chemotherapy-induced fatigue and quality of life in breast cancer patients. Integr Cancer Ther. 2013;12(4):312-22.
  14. Sharma AK, Basu I, Singh S. Efficacy and safety of Ashwagandha root extract in subclinical hypothyroid patients: a double-blind, randomized placebo-controlled trial. J Altern Complement Med. 2018 Mar;24(3):243-248. PubMed
  15. Durg S, Bavage S, Shivaram SB. Withania somnifera (Indian ginseng) in diabetes mellitus: A systematic review and meta-analysis of scientific evidence from experimental research to clinical application. Phytother Res. 2020;34(5):1041-1059.
  16. Björnsson HK, Björnsson ES, Avula B, et al. Ashwagandha-induced liver injury: A case series from Iceland and the US Drug-Induced Liver Injury Network. Liver Int. 2020;40(4):825-829. PubMed
  17. Tharakan A, Shukla H, Benny IR, Tharakan M, George L, Koshy S. Immunomodulatory Effect of Withania somnifera (Ashwagandha) Extract-A Randomized, Double-Blind, Placebo Controlled Trial with an Open Label Extension on Healthy Participants. J Clin Med 2021;1 PubMed
  18. Ireland PJ, Hardy T, Burt AD, Donnelly MC. Drug-induced hepatocellular injury due to herbal supplement ashwagandha. J R Coll Physicians Edinb. 2021;51(4):363-365. PubMed
  19. Kamal HI, Patel K, Brdak A, Heffernan J, Ahmad N. Ashwagandha as a unique cause of thyrotoxicosis presenting with supraventricular tachycardia. Cureus. 2022 Mar 25;14(3):e23494. PubMed
  20. Suryawanshi G, Abdallah M, Thomson M, Desai N, Chauhan A, Lim N. Ashwagandha-Associated Acute Liver Failure Requiring Liver Transplantation. Am J Ther 2023;30(1):e80-e83. PubMed
  21. Pusec CM, Wolsky R, Llerena C, Sura P. A Case of Supplement-Induced Hepatitis. Cureus 2022;14(10):e30433. PubMed
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Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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