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Dietary supplement

Fraxinus Ingredients & Drug Interactions

by Hawaii Pharm

Fraxinus label
See full label image
Liquid Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 23, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Fraxinus against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Fraxinus is a dietary supplement by Hawaii Pharm with 1 active ingredient. Its ingredients are commonly taken for joint pain and arthritis, fever, constipation.Based on those ingredients, 258 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Fraxinus Bark Extract, Dry. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Fraxinus by Hawaii Pharm

Ask about any prescription or over-the-counter medication and we check it for interactions with Fraxinus by Hawaii Pharm — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Fraxinus by Hawaii Pharm

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: Fraxinus Bark Extract in dry form. Fraxinus is the botanical name for ash tree.

The liquid formulation also includes alcohol, water, and glycerin as inactive ingredients to deliver the extract.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Ash product and its label doesn't state a use — see Ash's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence for Fraxinus Bark Extract to support weight loss is insufficient. We don't have reliable data showing it works for obesity, so we can't rate its effectiveness for that purpose at this time.

The evidence, ingredient by ingredient Ash

How safe is it?

Some data gaps
Safety Information · database check
Some gaps

Safety data exists for these ingredients, but with some important gaps.

Why this rating?
  • We hold adverse-effect (side-effect) data for 0 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Fraxinus Bark Extract is likely fine in the amounts you'd get from food, but medicinal use doesn't have strong safety data behind it. The safety information available isn't robust enough to give you a clear picture of how well it's tolerated when used as a supplement.

This product should be avoided during pregnancy — there isn't enough safety information to know it's okay for your baby. It should also be avoided while breastfeeding for the same reason: we don't have reliable safety data for nursing infants.

Talk with your doctor or pharmacist before use if you're pregnant, planning to become pregnant, or breastfeeding.

Side effects, ingredient by ingredient Ash

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Ash.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 258 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you start, double-check this product with your pharmacist if you take any blood pressure medications or diabetes drugs. Both have Moderate-severity interactions with this extract, and dosage adjustments might be needed.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and some safety-information gaps remain.

Fraxinus Bark Extract may be worth considering if you're interested in its traditional uses, but the evidence for weight loss is thin. If you take blood pressure or diabetes medications, this product isn't a casual add-on — check with your pharmacist first.

Pregnant or breastfeeding? Skip it until you've talked with your doctor.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Nov 22, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Fraxinus, straight from the product label.

Brand Hawaii Pharm
Barcode (UPC) 840253622631
Net contents 4 Fluid Ounce(s); 120 mL
Market status On market
Date entered into DSLD Nov 22, 2023
DSLD ID 301593
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Fraxinus by Hawaii Pharm, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
0.7 mL
Maximum serving Sizes:
1 mL
Servings per container
120
UPC/BARCODE
840253622631
IngredientAmount% DV
Fraxinus Bark Extract, Dry983 mg--

Other ingredients: Alcohol, Water, Glycerin

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Brand IP Statement(s)

Hawaii Pharm Herbal Extract Highest quality since 2008

Suggested/Recommended/Usage/Directions

Suggested use: Shake well before using. For adults add about 20-30 drops (0.7-1 mL, one full squeeze of the dropper bulb) to some juice or water, up to 4 times a day.

Precautions

Warning: We recommend to seek expert medical advice before taking.

Do not use if you are allergic to any ingredients.

Consult your physician before giving to children under 18, during pregnancy, if nursing or taking medications.

Consult your physician before giving to children under 18, during pregnancy, if nursing or taking medications.

May affect the ability to drive and operate machinery. May have contraindications, can cause side effects and adverse reactions. Do not use if seal is broken or missing.

Keep out of the reach of children!

Storage

Store in a cool dry place.

Seals/Symbols

cGMP Made in compliance with cGMP 21 CFR 111 in an FDA registered and inspected facility.

Organic Alcohol Based USA Made in United States of America

FDA Disclaimer Statement

This product has not been evaluated by the FDA and is not intended to diagnose, treat, cure or prevent any disease.

General Statements

Scan this QR-code to get 15% discount on your next purchase. Limited time deal.

Formula

Fraxinus chinensis

Organic Alcohol Based

Formulation

Only natural ingredients Purity is laboratory tested and verified

All the raw materials are gluten-free by their nature No artificial colors, flavors, or preservatives

Not tested on animals

Organic Alcohol Based

Made in USA, Hawaii

FDA Statement of Identity

Herbal Supplement

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Fraxinus by Hawaii Pharm label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Fraxinus label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Fraxinus by Hawaii Pharm

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size0.7 mL Dosage formLiquid Servings per container120 Amounts shown are per serving.

Fraxinus Bark Extract, Dry

Interacts with
258 drugs
983 mg per serving Form: Fraxinus chinensis Bark Extract, Dry

Ash (Fraxinus excelsior and related species) is a tree whose leaves, bark, and seeds have a long history in folk medicine for arthritis, fever, and fl...

Fraxinus Bark Extract, Dry monograph & interactions

Other (inactive) ingredients: Alcohol, Water, Glycerin. These complete the product’s ingredient list but are not active constituents.

Interaction report

Fraxinus by Hawaii Pharm Drug Interactions

Want to check YOUR meds against Fraxinus?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
258Drugs
258 Moderate

Ingredients driving the most interactions

Fraxinus Bark Extract, Dry 258

Individual Drug Interactions

The ingredients in Fraxinus interact with 258 drugs. Click any drug to see the details.

1 of the 1 ingredient in Fraxinus interact with drugs. Each result below shows which ingredient is responsible. Fraxinus Bark Extract, Dry

Each ingredient & the kinds of drugs it affects

For each ingredient in Fraxinus with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Fraxinus Bark Extract, Dry2 drug types · 258 drugs

Antidiabetes Drugs

Theoretically, concomitant use with antidiabetes drugs might affect glucose control and increase the risk of hypoglycemia. Dose adjustments to diabetes medications might be necessary. Animal research shows that ash seed/fruit extract reduces fasting levels of glucose. Although clinical research in patients without diabetes shows that ash seed/fruit extract does not significantly affect blood glucose levels, insulin levels, or homeostatic model of insulin resistance (HOMA-IR), it may lower the incremental glucose area under the curve and decrease 2-hour blood glucose following an oral glucose tolerance test. Ash seed/fruit extract has not been evaluated in patients with diabetes. Until more is known, use cautiously in patients taking antidiabetes drugs.
Some antidiabetes drugs include glimepiride (Amaryl), glyburide (DiaBeta, Glynase PresTab, Micronase), insulin, metformin (Glucophage), pioglitazone (Actos), rosiglitazone (Avandia), and others.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, concomitant use of ash seed with antihypertensive drugs might have additive blood pressure lowering effects. Animal research shows that ash seed extract can decrease blood pressure. This effect has not been evaluated in humans. Until more is known, use cautiously in patients taking antihypertensive drugs.
Some antihypertensive drugs include nifedipine (Adalat, Procardia), verapamil (Calan, Isoptin, Verelan), diltiazem (Cardizem), isradipine (DynaCirc), felodipine (Plendil), amlodipine (Norvasc), and others.

Likelihood Possible Evidence D
Fraxinus Bark Extract, Dry full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Fraxinus, from the product label.

Hawaii Pharm

See all Hawaii Pharm products
Name
Hawaii Pharm LLC
Street Address
510 Sumner St. Ste. 613
City
Honolulu
State
HI
ZipCode
96817
Phone Number
888-854-2924
Web Address
www.hawaiipharm.com
Pharmacist Counseling Corner

Fraxinus by Hawaii Pharm: Common Questions

Does Fraxinus by Hawaii Pharm interact with any medications?
Yes. Based on its ingredients, Fraxinus has a known interaction with 258 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Fraxinus contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does Fraxinus Bark Extract actually help with weight loss?
The evidence isn't established in the data we have. We can't rate how well it works for obesity, so we don't know yet whether it'll help you lose weight.
Is it safe to use this while I'm on blood pressure medication?
There's a concern here. Animal research shows ash seed extract can lower blood pressure, so taking it alongside your medication could drop your pressure too low. You'll need to talk with your pharmacist or doctor first — they may want to monitor you closely or adjust your dose.
What if I have diabetes and take insulin or other diabetes drugs?
This extract appears to lower blood sugar based on animal studies, which could add to the effect of your diabetes medication and risk dropping your blood sugar too low. Your doctor may need to adjust your diabetes medication dose. Check with your pharmacist before starting.
Can I take this while I'm pregnant or breastfeeding?
No — there isn't enough safety information for either. It's best avoided during pregnancy and while breastfeeding. Talk with your doctor if you're pregnant, planning to become pregnant, or nursing.
What's in the liquid besides the extract?
The formulation includes alcohol, water, and glycerin to deliver the ash bark extract in liquid form.
Does Fraxinus Bark Extract have any documented side effects?
We don't have adverse effects data on file for this ingredient. The safety information available is limited, so we don't have a clear picture of what side effects might occur with medicinal use.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Fraxinus is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Fraxinus label
Go deeper

The Full Monographs Behind Fraxinus’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Ash

Interacts with 258 drugs

Ash (Fraxinus excelsior and related species) is a tree whose leaves, bark, and seeds have a long history in folk medicine for arthritis, fever, and fluid retention. Solid human evidence is l...

Read the full Ash monograph →
Sources

Sources & How We Checked

Fraxinus's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 3 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Ash 3 references
  1. Zulet MA, Navas-Carretero S, Lara y Sánchez D, et al. A Fraxinus excelsior L. seeds/fruits extract benefits glucose homeostasis and adiposity related markers in elderly overweight/obese subjects: a longitudinal, randomized, crossover, double-blind,
  2. Montó F, Arce C, Noguera MA, et al. Action of an extract from the seeds of Fraxinus excelsior L. on metabolic disorders in hypertensive and obese animal models. Food Funct. 2014;5(4):786-96. PubMed
  3. Visen P, Saraswat B, Visen A, et al. Acute effects of Fraxinus excelsior L. seed extract on postprandial glycemia and insulin secretion on healthy volunteers. J Ethnopharmacol. 2009;126(2):226-32. PubMed

See these in context on the Ash monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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